CN101343243A - 制备氨基甲酸2-(取代苯基)-2-羟基-乙酯的方法 - Google Patents

制备氨基甲酸2-(取代苯基)-2-羟基-乙酯的方法 Download PDF

Info

Publication number
CN101343243A
CN101343243A CNA2008102106749A CN200810210674A CN101343243A CN 101343243 A CN101343243 A CN 101343243A CN A2008102106749 A CNA2008102106749 A CN A2008102106749A CN 200810210674 A CN200810210674 A CN 200810210674A CN 101343243 A CN101343243 A CN 101343243A
Authority
CN
China
Prior art keywords
compound
formula
group
contain
solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2008102106749A
Other languages
English (en)
Chinese (zh)
Inventor
M·雷
T·奥滕
D·科雷
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
3 Dimensional Pharmaceuticals Inc
Original Assignee
3 Dimensional Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3 Dimensional Pharmaceuticals Inc filed Critical 3 Dimensional Pharmaceuticals Inc
Publication of CN101343243A publication Critical patent/CN101343243A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/04—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/12—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNA2008102106749A 2001-12-21 2002-12-19 制备氨基甲酸2-(取代苯基)-2-羟基-乙酯的方法 Pending CN101343243A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01205097.7 2001-12-21
EP01205097 2001-12-21
US60/418084 2002-10-11

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNB028281128A Division CN100457723C (zh) 2001-12-21 2002-12-19 制备氨基甲酸2-(取代苯基)-2-羟基-乙酯的方法

Publications (1)

Publication Number Publication Date
CN101343243A true CN101343243A (zh) 2009-01-14

Family

ID=35519523

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2008102106749A Pending CN101343243A (zh) 2001-12-21 2002-12-19 制备氨基甲酸2-(取代苯基)-2-羟基-乙酯的方法

Country Status (5)

Country Link
KR (2) KR100945720B1 (ko)
CN (1) CN101343243A (ko)
CA (1) CA2752518A1 (ko)
EA (1) EA007741B1 (ko)
ZA (1) ZA200405782B (ko)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5504108A (en) * 1990-01-12 1996-04-02 The Ohio State University Research Foundation Optically pure 4-aryl-2-hydroxytetronic acids
JP3010497B2 (ja) * 1990-05-31 2000-02-21 チッソ株式会社 光学活性α―ヒドロキシエステル類の製造方法
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
WO2001040168A1 (fr) * 1999-11-29 2001-06-07 Mitsubishi Rayon Co., Ltd. Derive d'acetalsulfonate, son procede de fabrication et obtention d'un derive d'oxyde styrene

Also Published As

Publication number Publication date
ZA200405782B (en) 2005-08-29
EA007741B1 (ru) 2006-12-29
KR20100134082A (ko) 2010-12-22
EA200400850A1 (ru) 2004-10-28
CA2752518A1 (en) 2003-07-03
KR100945720B1 (ko) 2010-03-05
KR20040068588A (ko) 2004-07-31

Similar Documents

Publication Publication Date Title
CN102712585A (zh) 中性内肽酶抑制剂中间体和其制备方法
CN111592467B (zh) 尼拉帕尼中间体及其制备方法和用途和尼拉帕尼的合成方法
CN100457723C (zh) 制备氨基甲酸2-(取代苯基)-2-羟基-乙酯的方法
CN101343243A (zh) 制备氨基甲酸2-(取代苯基)-2-羟基-乙酯的方法
CN114031505B (zh) 一种制备喷他佐辛中间体的方法
CN106674281B (zh) 一种瑞舒伐他汀中间体化合物、制备方法及其用途
JP4667593B2 (ja) ２−アルキル−２−アダマンチル（メタ）アクリレート類の製造法
CN109575021B (zh) 一种哌柏西利的制备方法
CN109574860A (zh) 一种制备维兰特罗的方法
CN106554301A (zh) 一种沙格列汀关键中间体的制备方法
CN113620869B (zh) 一种贝曲西班的制备方法
CN112552200B (zh) 一种光学纯4-(1-氨基)乙基苯甲酸酯及其盐的制备方法
CN115819186B (zh) 一种3,5-二氯苯甲醇的新型制备方法
CN111072543B (zh) 一种(3r,4s)-4-乙基吡咯烷-3-羧酸类化合物的制备方法及其应用
AU2021377857A1 (en) Method for producing 4-borono-l-phenylalanine and intermediate thereof
EP2855421B1 (en) Process for the preparation of optically active 3,3-diphenylpropylamines
WO2002060888A1 (en) Processes for preparing chromanylbenzoic acids
CN118164846A (zh) 一种右酮洛芬合成方法及其中间体和用途
CN115160162A (zh) 一种α氨基β酮酸酯的不对称氢化方法
JP2004307402A (ja) ２−カルボキシエチルジメチルスルホニウム硫酸塩の製造方法
CN106349087A (zh) （r）‑2‑氨基‑3‑（联苯基‑4‑基）‑1‑丙醇的合成
WO1997034864A1 (en) STEREOSELECTIVE PROCESS FOR PREPARATION OF (2R,3S)-β-PHENYLISOSERINE DERIVATIVE
JPH01149747A (ja) テルペンジオール誘導体の製造方法
JP2006076911A (ja) スピロキラリティを有する第４級アンモニウム塩およびその製造法、並びに該アンモニウム塩を用いた不斉触媒反応
JPH05331102A (ja) 光学活性シトロネル酸誘導体又はその対掌体の製法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Open date: 20090114