CA2752389C - Use of ingenols in the treatment of aged skin - Google Patents

Use of ingenols in the treatment of aged skin Download PDF

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Publication number
CA2752389C
CA2752389C CA2752389A CA2752389A CA2752389C CA 2752389 C CA2752389 C CA 2752389C CA 2752389 A CA2752389 A CA 2752389A CA 2752389 A CA2752389 A CA 2752389A CA 2752389 C CA2752389 C CA 2752389C
Authority
CA
Canada
Prior art keywords
euphorbia
pep005
skin
ingenol
hyaluronan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2752389A
Other languages
English (en)
French (fr)
Other versions
CA2752389A1 (en
Inventor
Steven Martin Ogbourne
David Thomas
Ryan Moseley
James Harrison Aylward
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leo Laboratories Ltd
Original Assignee
Leo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Laboratories Ltd filed Critical Leo Laboratories Ltd
Publication of CA2752389A1 publication Critical patent/CA2752389A1/en
Application granted granted Critical
Publication of CA2752389C publication Critical patent/CA2752389C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/18—Antioxidants, e.g. antiradicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Emergency Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
CA2752389A 2009-02-13 2010-02-12 Use of ingenols in the treatment of aged skin Expired - Fee Related CA2752389C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15259909P 2009-02-13 2009-02-13
US61/152,599 2009-02-13
PCT/AU2010/000152 WO2010091472A1 (en) 2009-02-13 2010-02-12 Skin treatment

Publications (2)

Publication Number Publication Date
CA2752389A1 CA2752389A1 (en) 2010-08-19
CA2752389C true CA2752389C (en) 2017-01-03

Family

ID=42561329

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2752389A Expired - Fee Related CA2752389C (en) 2009-02-13 2010-02-12 Use of ingenols in the treatment of aged skin

Country Status (14)

Country Link
US (1) US10143638B2 (enExample)
EP (1) EP2395993B1 (enExample)
JP (1) JP5638008B2 (enExample)
CN (1) CN102316866A (enExample)
AU (1) AU2010213362B2 (enExample)
CA (1) CA2752389C (enExample)
DK (1) DK2395993T3 (enExample)
ES (1) ES2633755T3 (enExample)
IL (1) IL214133A (enExample)
NZ (1) NZ594184A (enExample)
PL (1) PL2395993T3 (enExample)
PT (1) PT2395993T (enExample)
RU (1) RU2491050C2 (enExample)
WO (1) WO2010091472A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012080466A2 (en) 2010-12-17 2012-06-21 Leo Pharma A/S Ingenols for treating seborrheic keratosis
US9388124B2 (en) 2010-12-22 2016-07-12 Leo Laboratories Limited Ingenol-3-acylates I
AU2011348638B2 (en) * 2010-12-22 2015-05-21 Leo Laboratories Limited 3-acyl-ingenols II
WO2012176015A1 (en) 2011-06-24 2012-12-27 Leo Pharma A/S Methods for treating uv-damaged skin and scc tumors and for removing tattoos with topical ingenol mebutate
EP2790670A1 (en) * 2011-12-12 2014-10-22 Leo Laboratories Limited Gel compositions
WO2013088381A1 (en) * 2011-12-12 2013-06-20 Leo Laboratories Limited Gel compositions
US20150366789A1 (en) * 2013-03-13 2015-12-24 Avon Place, Inc. Glochidium wallichianum extracts and methods of use
US9526714B2 (en) 2014-03-24 2016-12-27 Leo Laboratories Limited Method for treating skin lesions with ingenol mebutate
AU2014100280B4 (en) * 2014-03-24 2015-01-15 Leo Pharma A/S A method of treating skin lesions
US11478409B2 (en) * 2016-05-24 2022-10-25 Natura Cosmeticos S.A. Anti-wrinkle cosmetic composition, composition system and method for cosmetic skin treatment
JP7557192B2 (ja) 2020-08-19 2024-09-27 日本メナード化粧品株式会社 皮膚外用剤及び内用剤

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08176004A (ja) * 1994-12-21 1996-07-09 Lion Corp 生体老化防止剤及び皮膚用組成物
JPH0987136A (ja) * 1995-07-13 1997-03-31 Shiseido Co Ltd 皮膚外用剤
AUPO864097A0 (en) * 1997-08-19 1997-09-11 Peplin Pty Ltd Anti-cancer compounds
AU750624B2 (en) * 1997-08-19 2002-07-25 Leo Laboratories Limited Anti-cancer compounds-I
KR20010057776A (ko) * 1999-12-23 2001-07-05 성재갑 피부미백제
JP4880816B2 (ja) 2000-12-15 2012-02-22 株式会社ヤクルト本社 皮膚老化防止剤
JP3935360B2 (ja) * 2002-01-22 2007-06-20 丸善製薬株式会社 ヒアルロン酸産生促進剤並びに皮膚化粧料及び美容用飲食品
RU2229293C1 (ru) * 2003-04-24 2004-05-27 Хазанов Вениамин Абрамович Лечебно-профилактическое средство для использования в геронтологической практике
US20070224150A1 (en) * 2005-03-24 2007-09-27 Yongji Chung Growth factor for hair and skin treatment
JP2007084448A (ja) * 2005-09-20 2007-04-05 Shiseido Co Ltd ヒアルロン酸産生促進剤および皮膚外用剤
BRPI0504797B1 (pt) * 2005-10-27 2020-02-04 Pele Nova Biotecnologia S.A. formulação tópica, método de tratamento cosmético para rejuvenescimento da pele, método de tratamento cosmético e uso de uma formulação
CN101360506A (zh) * 2005-11-25 2009-02-04 派普林研究股份有限公司 创伤愈合的方法
HRP20160181T1 (hr) * 2007-04-30 2016-05-06 Leo Laboratories Limited Tretman virusno induciranih lezija
AU2011241893B2 (en) * 2010-04-16 2014-11-06 Leo Pharma A/S Crystalline ingenol mebutate

Also Published As

Publication number Publication date
EP2395993B1 (en) 2017-06-21
EP2395993A1 (en) 2011-12-21
US20120041064A1 (en) 2012-02-16
CN102316866A (zh) 2012-01-11
RU2011137530A (ru) 2013-03-20
IL214133A0 (en) 2011-08-31
NZ594184A (en) 2014-01-31
JP5638008B2 (ja) 2014-12-10
AU2010213362B2 (en) 2015-07-02
ES2633755T3 (es) 2017-09-25
IL214133A (en) 2015-03-31
RU2491050C2 (ru) 2013-08-27
AU2010213362A1 (en) 2011-08-04
DK2395993T3 (en) 2017-08-07
PT2395993T (pt) 2017-07-18
EP2395993A4 (en) 2014-09-03
WO2010091472A1 (en) 2010-08-19
PL2395993T3 (pl) 2017-10-31
JP2012517450A (ja) 2012-08-02
CA2752389A1 (en) 2010-08-19
US10143638B2 (en) 2018-12-04

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Effective date: 20150122

MKLA Lapsed

Effective date: 20200212