CA2743322A1 - Apparatus and methods for processing tissue to release cells - Google Patents

Apparatus and methods for processing tissue to release cells Download PDF

Info

Publication number
CA2743322A1
CA2743322A1 CA2743322A CA2743322A CA2743322A1 CA 2743322 A1 CA2743322 A1 CA 2743322A1 CA 2743322 A CA2743322 A CA 2743322A CA 2743322 A CA2743322 A CA 2743322A CA 2743322 A1 CA2743322 A1 CA 2743322A1
Authority
CA
Canada
Prior art keywords
housing
tissue
wall
housings
relative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2743322A
Other languages
English (en)
French (fr)
Inventor
Kyungyoon Min
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter Healthcare SA
Original Assignee
Baxter Healthcare SA
Baxalta GmbH
Baxter International Inc
Baxalta Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/263,984 external-priority patent/US20100112695A1/en
Application filed by Baxter Healthcare SA, Baxalta GmbH, Baxter International Inc, Baxalta Inc filed Critical Baxter Healthcare SA
Publication of CA2743322A1 publication Critical patent/CA2743322A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00Means for pre-treatment of biological substances
    • C12M45/02Means for pre-treatment of biological substances by mechanical forces; Stirring; Trituration; Comminuting
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00Means for pre-treatment of biological substances
    • C12M45/09Means for pre-treatment of biological substances by enzymatic treatment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04Cell isolation or sorting

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Mechanical Engineering (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Sampling And Sample Adjustment (AREA)
CA2743322A 2008-11-03 2009-10-29 Apparatus and methods for processing tissue to release cells Abandoned CA2743322A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12/263,984 US20100112695A1 (en) 2008-11-03 2008-11-03 Apparatus And Methods For Processing Tissue to Release Cells
US12/263,984 2008-11-03
US12/407,946 US20100112696A1 (en) 2008-11-03 2009-03-20 Apparatus And Methods For Processing Tissue To Release Cells
US12/407,946 2009-03-20
PCT/US2009/062584 WO2010062665A1 (en) 2008-11-03 2009-10-29 Apparatus and methods for processing tissue to release cells

Publications (1)

Publication Number Publication Date
CA2743322A1 true CA2743322A1 (en) 2010-06-03

Family

ID=41786235

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2743322A Abandoned CA2743322A1 (en) 2008-11-03 2009-10-29 Apparatus and methods for processing tissue to release cells

Country Status (8)

Country Link
US (2) US20100112696A1 (es)
EP (1) EP2352813B1 (es)
JP (1) JP5422661B2 (es)
CN (1) CN102264889B (es)
CA (1) CA2743322A1 (es)
ES (1) ES2397064T3 (es)
MX (1) MX2011004686A (es)
WO (1) WO2010062665A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
PL2502986T3 (pl) * 2011-03-22 2019-12-31 Cartiregen B.V. Układ do przetwarzania komórek chrzęstnych
JP5848541B2 (ja) 2011-07-26 2016-01-27 日本光電工業株式会社 細胞単離器具
EP2677024B1 (de) 2012-06-22 2019-11-20 Human Med AG Vorrichtung zum Separieren von adulten Stammzellen
GB2509780B (en) * 2013-01-15 2019-08-28 Brightwake Ltd Fat Processing Device
EP3027235A1 (en) 2013-07-30 2016-06-08 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
CA2986702C (en) 2015-05-21 2023-04-04 David Wang Modified demineralized cortical bone fibers
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
DK3430122T3 (da) * 2016-03-17 2021-08-23 Synova Life Sciences Inc Separering, adskillelse og/eller opdeling af celler ved hjælp af mekaniske stød
EP3239286A1 (en) * 2016-04-26 2017-11-01 Ludwig Boltzmann Gesellschaft Non-enzymatic method and milling device
EP3238760B1 (en) * 2016-04-29 2019-10-02 Fenwal, Inc. System and method for selecting and culturing cells
US10251990B2 (en) 2016-04-29 2019-04-09 Fenwal, Inc. System and method for processing, incubating, and/or selecting biological cells
US11724036B2 (en) 2016-12-12 2023-08-15 Orchid Holdings, Llc Syringe for processing fat grafts and related methods
US10274495B2 (en) 2016-12-21 2019-04-30 Fenwal, Inc. System and method for separating cells incorporating magnetic separation
IT201700059930A1 (it) * 2017-06-01 2017-09-01 C T S V S R L Dispositivo disgregatore di sostanze biologiche.
EP3650531A1 (en) * 2018-11-09 2020-05-13 DSM IP Assets B.V. Adipose tissue processing device
US11879121B2 (en) 2021-04-20 2024-01-23 CisNovo Tissue disaggregation system and methods
KR102507420B1 (ko) * 2021-10-05 2023-03-07 의료법인 명지의료재단 세포배양용 조직 분쇄 및 효소 반응기

Family Cites Families (108)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1002347A (en) * 1910-07-18 1911-09-05 John Wemer Agitator.
US3750645A (en) * 1970-10-20 1973-08-07 Becton Dickinson Co Method of collecting blood and separating cellular components thereof
US4035294A (en) * 1975-05-23 1977-07-12 Denver Chemical Manufacturing Company Pressure differential filtering device and method
US4040959A (en) * 1976-06-22 1977-08-09 Berman Irwin R Multi-purpose blood bag
US4066414A (en) * 1977-02-15 1978-01-03 Donald Selby One piece tube and microscope slide manipulative laboratory device
US4268393A (en) * 1980-05-05 1981-05-19 The Institutes Of Medical Sciences Apparatus for centrifugal separation of platelet-rich plasma
US4582606A (en) * 1984-01-30 1986-04-15 Neotech, Inc. Apparatus for separating or collecting different density liquid components
IL74967A (en) * 1985-04-18 1988-10-31 Assaf Pharmaceutical Ind Separation of materials from a liquid dispersion by sedimentation
US5628781A (en) * 1985-06-06 1997-05-13 Thomas Jefferson University Implant materials, methods of treating the surface of implants with microvascular endothelial cells, and the treated implants themselves
US5035708A (en) * 1985-06-06 1991-07-30 Thomas Jefferson University Endothelial cell procurement and deposition kit
US5441539A (en) * 1985-06-06 1995-08-15 Thomas Jefferson University Endothelial cell deposition device
US5230693A (en) * 1985-06-06 1993-07-27 Thomas Jefferson University Implantable prosthetic device for implantation into a human patient having a surface treated with microvascular endothelial cells
US4820626A (en) * 1985-06-06 1989-04-11 Thomas Jefferson University Method of treating a synthetic or naturally occuring surface with microvascular endothelial cells, and the treated surface itself
US4772273A (en) * 1985-12-13 1988-09-20 Becton, Dickinson And Company Variable-volume vented container
GB8604497D0 (en) * 1986-02-24 1986-04-03 Connaught Lab Separation of islets of langerhans
ES2004281A6 (es) * 1986-04-04 1988-12-16 Univ Jefferson Una superficie protesica implantable para implantacion en un paciente humano
EP0258795B1 (en) * 1986-08-27 1993-11-03 Kawasumi Laboratories, Inc. A method for cultivating cells and an instrument therefor
US4683916A (en) * 1986-09-25 1987-08-04 Burron Medical Inc. Normally closed automatic reflux valve
US4811866A (en) * 1987-01-02 1989-03-14 Helena Laboratories Corporation Method and apparatus for dispensing liquids
US6780333B1 (en) * 1987-01-30 2004-08-24 Baxter International Inc. Centrifugation pheresis method
US5079160A (en) * 1987-06-08 1992-01-07 Lacy Paul E Method to isolate clusters of cell subtypes from organs
US4834703A (en) * 1987-11-23 1989-05-30 Dubrul Will R Liposuction filter and lipoplasty device
CA1335167C (en) * 1988-01-25 1995-04-11 Steven C. Jepson Pre-slit injection site and associated cannula
DE68927896T2 (de) * 1988-01-25 1997-10-23 Baxter Int Vorgeschlitzte Injektionsstelle und Spritz zulaufende Kanüle
US4981654A (en) * 1988-05-06 1991-01-01 Davstar Industries, Inc. Unitary centrifuge tube and separable dispensing receptacle
US5536475A (en) * 1988-10-11 1996-07-16 Baxter International Inc. Apparatus for magnetic cell separation
US5312386A (en) * 1989-02-15 1994-05-17 Johnson & Johnson Disposable sanitary pad
US5103821A (en) * 1989-03-06 1992-04-14 Angeion Corporation Method of providing a biological pacemaker
US5019512A (en) * 1989-03-17 1991-05-28 Baxter International Inc. Spin filter for removing substantially cell-free culture medium from suspension cell culture system
JPH0394828A (ja) * 1989-09-05 1991-04-19 Mochida Pharmaceut Co Ltd 反応容器着脱装置および固相と液相との反応装置
US5030215A (en) * 1990-01-03 1991-07-09 Cryolife, Inc. Preparation of fibrinogen/factor XIII precipitate
EP0459949B1 (de) * 1990-05-30 1996-01-03 Ciba-Geigy Ag Sulfonylharnstoffe mit herbizider und pflanzenwuchsregulierender Wirkung
US5115054A (en) * 1990-10-12 1992-05-19 Phillips Petroleum Company Catalysts containing poly(3-ethyl-1-hexene) and uses thereof
NZ242533A (en) * 1991-05-03 1995-05-26 Becton Dickinson Co Device for collecting and processing fat tissue; vessel with rinsing and digesting chamber, drain chamber and isolation chamber
US5238922A (en) * 1991-09-30 1993-08-24 Merck & Co., Inc. Inhibitors of farnesyl protein transferase
AU665813B2 (en) * 1992-05-11 1996-01-18 Sulzer Medizinaltechnik Ag Process and apparatus for producing endoprostheses
US5957972A (en) * 1992-09-29 1999-09-28 Arizona Board Of Regents On Behalf Of The University Of Arizona Implants possessing a surface of endothelial cells genetically-modified to inhibit intimal thickening
US5316681A (en) * 1992-11-06 1994-05-31 Baxter International Inc. Method of filtering body fluid using a rinse chamber bag
US6832996B2 (en) * 1995-06-07 2004-12-21 Arthrocare Corporation Electrosurgical systems and methods for treating tissue
US5409833A (en) * 1993-07-01 1995-04-25 Baxter International Inc. Microvessel cell isolation apparatus
US5686301A (en) * 1993-09-02 1997-11-11 Heraeus Instruments Gmbh Culture vessel for cell cultures
US5437998A (en) * 1993-09-09 1995-08-01 Synthecon, Inc. Gas permeable bioreactor and method of use
US5931969A (en) * 1994-07-29 1999-08-03 Baxter International Inc. Methods and apparatuses for treating biological tissue to mitigate calcification
FR2729398A1 (fr) * 1995-01-17 1996-07-19 Hospal R & D Int Dispositif de digestion d'organe et procede pour isoler des cellules ou amas de cellules d'interet biologique a partir d'un organe
US5804366A (en) * 1995-02-09 1998-09-08 Baxter International Inc. Method and apparatus for sodding microvessel cells onto a synthetic vascular graft
US5679565A (en) * 1995-04-10 1997-10-21 The Regents Of The University Of California Method of preserving pancreatic islets
US5707331A (en) * 1995-05-05 1998-01-13 John R. Wells Automatic multiple-decanting centrifuge
USRE38730E1 (en) * 1995-05-05 2005-04-26 Harvest Technologies Corporation Automatic multiple-decanting centrifuge and method of treating physiological fluids
US5888409A (en) * 1995-06-07 1999-03-30 Cedars-Sinai Medical Center Methods for cell isolation and collection
US5656154A (en) * 1995-06-07 1997-08-12 Organ, Inc. Method and apparatus for separating a fluid into components and for washing a material
US5707876A (en) * 1996-03-25 1998-01-13 Stephen C. Wardlaw Method and apparatus for harvesting constituent layers from a centrifuged material mixture
AU6467796A (en) * 1996-04-24 1997-05-15 Claude Fell Cell separation system for biological fluids like blood
WO2000062828A1 (en) * 1996-04-30 2000-10-26 Medtronic, Inc. Autologous fibrin sealant and method for making the same
PT952868E (pt) * 1996-11-18 2004-08-31 Nypro Inc Valvula conica-luer lavavel
US5957898A (en) * 1997-05-20 1999-09-28 Baxter International Inc. Needleless connector
NZ333508A (en) * 1997-05-20 2000-07-28 Baxter Int Needleless luer connector, resilient diaphragm with central slit seals against luer
US5786207A (en) * 1997-05-28 1998-07-28 University Of Pittsburgh Tissue dissociating system and method
GB9808460D0 (en) * 1997-07-07 1998-06-17 Univ Bristol Porous container,and apparatus for use with the porous container
DE19729028C1 (de) * 1997-07-08 1999-05-06 Fraunhofer Ges Forschung Vorrichtung sowie Verfahren zur Isolierung von Zellmaterial aus einem Gewebeverband und/oder einer Flüssigkeit
US6123696A (en) * 1998-07-16 2000-09-26 Thermogenesis Corp. Centrifugation bag with yieldable partitions
US6448076B2 (en) * 1998-09-15 2002-09-10 The Regents Of The University Of Michigan Method for chemically acellularizing a biological tissue sample
US6280400B1 (en) * 1998-12-05 2001-08-28 Becton Dickinson And Company Device and method for separating component of a liquid sample
EP1025904B1 (en) * 1999-02-02 2007-05-09 Nipro Corporation Tube for sperm washing and concentration and method for sperm washing and concentration
US20050153442A1 (en) * 1999-03-10 2005-07-14 Adam Katz Adipose-derived stem cells and lattices
US6777231B1 (en) * 1999-03-10 2004-08-17 The Regents Of The University Of California Adipose-derived stem cells and lattices
US20050076396A1 (en) * 1999-03-10 2005-04-07 Katz Adam J. Adipose-derived stem cells and lattices
US20030082152A1 (en) * 1999-03-10 2003-05-01 Hedrick Marc H. Adipose-derived stem cells and lattices
US20030050591A1 (en) * 2000-02-08 2003-03-13 Patrick Mchale Anthony Loading system and method for using the same
US6988004B2 (en) * 2000-05-16 2006-01-17 Bioheart, Inc. Method for inducing angiogenesis by electrical stimulation of muscles
US7686799B2 (en) * 2000-07-13 2010-03-30 Abbott Cardiovascular Systems Inc. Deployment system for myocardial cellular material
US20020146817A1 (en) * 2000-10-02 2002-10-10 Cannon Thomas F. Automated bioculture and bioculture experiments system
JP4195287B2 (ja) * 2000-10-02 2008-12-10 エフ.キャノン トーマス 自動化されたバイオカルチャー及びバイオカルチャー実験システム
US6602718B1 (en) * 2000-11-08 2003-08-05 Becton, Dickinson And Company Method and device for collecting and stabilizing a biological sample
US20020077687A1 (en) * 2000-12-14 2002-06-20 Ahn Samuel S. Catheter assembly for treating ischemic tissue
US7045349B2 (en) * 2001-01-23 2006-05-16 Benedict Daniel J Method of islet isolation using process control
US7341062B2 (en) * 2001-03-12 2008-03-11 Bioheart, Inc. Method of providing a dynamic cellular cardiac support
JP2004536794A (ja) * 2001-04-09 2004-12-09 メドトロニック、インコーポレイテッド マイクロ遠心機を用いる血液成分の分離方法及びその使用法
US6610002B2 (en) * 2001-04-09 2003-08-26 Medtronic, Inc. Method for handling blood sample to ensure blood components are isolated
US7483749B2 (en) * 2001-06-13 2009-01-27 Bioheart, Inc. Method of enhancing myogenesis by electrical stimulation
US6623959B2 (en) * 2001-06-13 2003-09-23 Ethicon, Inc. Devices and methods for cell harvesting
US6589153B2 (en) * 2001-09-24 2003-07-08 Medtronic, Inc. Blood centrifuge with exterior mounted, self-balancing collection chambers
US7514075B2 (en) * 2001-12-07 2009-04-07 Cytori Therapeutics, Inc. Systems and methods for separating and concentrating adipose derived stem cells from tissue
WO2003053346A2 (en) * 2001-12-07 2003-07-03 Macropore Biosurgery, Inc. Systems and methods for treating patients with processed lipoaspirate cells
US7651684B2 (en) * 2001-12-07 2010-01-26 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in augmenting autologous fat transfer
US7595043B2 (en) * 2001-12-07 2009-09-29 Cytori Therapeutics, Inc. Method for processing and using adipose-derived stem cells
US7188994B2 (en) * 2002-02-22 2007-03-13 Biorep Technologies, Inc. Orbital shaker for cell extraction
US9144583B2 (en) * 2002-03-29 2015-09-29 Tissue Genesis, Inc. Cell separation apparatus and methods of use
US6905612B2 (en) * 2003-03-21 2005-06-14 Hanuman Llc Plasma concentrate apparatus and method
EP1549552B1 (en) * 2002-09-19 2013-06-26 Harvest Technologies Corporation Sterile disposable unit
EP1578995A2 (en) * 2002-11-18 2005-09-28 Agency for Science, Technology and Research Method and system for cell and/or nucleic acid molecules isolation
SG150387A1 (en) * 2003-05-02 2009-03-30 Insception Bioscience Inc Apparatus and methods for amplification of blood stem cell numbers
US7333736B2 (en) * 2003-07-02 2008-02-19 Ciena Corporation Method and apparatus for controlling modulator phase alignment in a transmitter of an optical communications system
CA2539177A1 (en) * 2003-09-22 2005-04-07 Lawrence Bullen Tissue dissociation device
US20050125049A1 (en) * 2003-10-21 2005-06-09 The Regents Of The University Of Michigan Tissue engineered vascular construct and method for producing same
US7108679B2 (en) * 2004-03-11 2006-09-19 Becton, Dickinson And Company Intradermal syringe and needle assembly
DE202004010672U1 (de) * 2004-07-07 2004-11-25 Biotek Technology Corp., Chung-Li Mixerfilter
US20060045872A1 (en) * 2004-08-25 2006-03-02 Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco Use of adipose tissue-derived stromal stem cells in treating fistula
WO2006062989A1 (en) * 2004-12-07 2006-06-15 Bacterin International, Inc. Three-dimensional cell culsture system
TWI266631B (en) * 2004-12-16 2006-11-21 Chih Shin Biomedical Technolog Method and apparatus are provided for rapid cell separation
EP1981963A1 (de) * 2004-12-27 2008-10-22 Fresenius Medical Care Deutschland GmbH Reaktor und reaktoreinheit mit hohlfasern
PL1848473T3 (pl) * 2005-02-07 2013-11-29 Hanuman Llc Urządzenie - koncentrator osocza
KR20060129647A (ko) * 2005-06-13 2006-12-18 노틸러스효성 주식회사 금융자동화기기의 출금장치
US7771590B2 (en) * 2005-08-23 2010-08-10 Biomet Manufacturing Corp. Method and apparatus for collecting biological materials
KR100679642B1 (ko) * 2005-11-16 2007-02-06 주식회사 알앤엘바이오 인간 지방조직 유래 다분화능 줄기세포 및 이를 함유하는세포치료제
US20070154465A1 (en) * 2005-12-30 2007-07-05 Alexandar Kharazi Stem cell therapy for retinal disease
CA2661935C (en) * 2006-08-29 2013-07-09 Tissue Genesis, Inc. Catheter for cell delivery
CN101517067B (zh) * 2006-09-21 2014-08-06 特苏詹尼斯公司 细胞递送基质
DE102007005369A1 (de) * 2007-02-02 2008-08-07 Eppendorf Ag Vorrichtung und Verfahren zur mechanischen Vereinzelung von Zellen aus einem Zellverbund

Also Published As

Publication number Publication date
WO2010062665A1 (en) 2010-06-03
CN102264889B (zh) 2013-11-06
EP2352813B1 (en) 2012-10-03
CN102264889A (zh) 2011-11-30
JP5422661B2 (ja) 2014-02-19
EP2352813A1 (en) 2011-08-10
US20130005024A1 (en) 2013-01-03
JP2012507298A (ja) 2012-03-29
ES2397064T3 (es) 2013-03-04
US20100112696A1 (en) 2010-05-06
MX2011004686A (es) 2011-07-19

Similar Documents

Publication Publication Date Title
EP2352813B1 (en) Apparatus and methods for processing tissue to release cells
US20100112695A1 (en) Apparatus And Methods For Processing Tissue to Release Cells
US6642019B1 (en) Vessel, preferably spherical or oblate spherical for growing or culturing cells, cellular aggregates, tissues and organoids and methods for using same
US10428301B2 (en) System, apparatus and method for material preparation and/or handling
CN104363972B (zh) 离心动态过滤装置及利用其的细胞分离系统
JP5774608B2 (ja) 流体媒質において化学的変換を実施する装置
US8317168B2 (en) Mixer, mixing device and unit for measuring medical component
KR20190128546A (ko) 생물 반응기 시스템 및 그 방법
US8741136B2 (en) Device and method for treating or cleaning sample material, in particular nucleic acids
WO2018235102A1 (en) DEVICE FOR INSULATING STROMAL VASCULAR FRACTION FROM ADIPOSE TISSUE
CN103501913A (zh) 磁性颗粒清除装置及方法
US9314753B2 (en) Multi plane mixer and separator (MPMS) system
CN207793239U (zh) 一种干细胞分离装置
AU2013308131B2 (en) Multi plane mixer and separator (MPMS) system
JP2017501018A (ja) 生物学的または化学的形質転換用リアクタ
CN211329002U (zh) 一种用于生物医药药品制备的搅拌灌装设备
CN111154645A (zh) 搅拌器、细胞培养罐以及培养方法
JP3680080B2 (ja) 反応装置およびその使用方法
JPWO2002042430A1 (ja) 核酸抽出装置

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20180102