CA2727285A1 - Inhibition of hrp-3 using modified oligonucleotides - Google Patents
Inhibition of hrp-3 using modified oligonucleotides Download PDFInfo
- Publication number
- CA2727285A1 CA2727285A1 CA2727285A CA2727285A CA2727285A1 CA 2727285 A1 CA2727285 A1 CA 2727285A1 CA 2727285 A CA2727285 A CA 2727285A CA 2727285 A CA2727285 A CA 2727285A CA 2727285 A1 CA2727285 A1 CA 2727285A1
- Authority
- CA
- Canada
- Prior art keywords
- hrp
- building blocks
- oligonucleotide molecule
- nucleotide
- oligonucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US6057108P | 2008-06-11 | 2008-06-11 | |
| US61/060,571 | 2008-06-11 | ||
| PCT/EP2009/004186 WO2009149921A2 (en) | 2008-06-11 | 2009-06-10 | Inhibition of hrp-3 using modified oligonucleotides |
Publications (1)
| Publication Number | Publication Date |
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| CA2727285A1 true CA2727285A1 (en) | 2009-12-17 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2727285A Abandoned CA2727285A1 (en) | 2008-06-11 | 2009-06-10 | Inhibition of hrp-3 using modified oligonucleotides |
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| EP (1) | EP2304031A2 (enExample) |
| JP (1) | JP5559159B2 (enExample) |
| AU (1) | AU2009256906A1 (enExample) |
| CA (1) | CA2727285A1 (enExample) |
| WO (1) | WO2009149921A2 (enExample) |
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| WO2011130371A1 (en) * | 2010-04-13 | 2011-10-20 | Life Technologies Corporation | Compositions and methods for inhibition of nucleic acids function |
| KR101701235B1 (ko) * | 2013-09-30 | 2017-02-03 | 한국원자력의학원 | Ｈｒｐ-3 억제제를 포함하는 방사선 또는 약물내성 암의 치료용 약학 조성물 |
| GB201410693D0 (en) | 2014-06-16 | 2014-07-30 | Univ Southampton | Splicing modulation |
| CN107109411B (zh) | 2014-10-03 | 2022-07-01 | 冷泉港实验室 | 核基因输出的定向增加 |
| CN108603230A (zh) | 2015-10-09 | 2018-09-28 | 南安普敦大学 | 基因表达的调节与蛋白质表达失调的筛选 |
| US11096956B2 (en) | 2015-12-14 | 2021-08-24 | Stoke Therapeutics, Inc. | Antisense oligomers and uses thereof |
| CN116059236A (zh) | 2015-12-14 | 2023-05-05 | 冷泉港实验室 | 用于治疗常染色体显性精神发育迟滞5型和Dravet综合征的反义寡聚体 |
| KR20260009385A (ko) | 2017-08-25 | 2026-01-19 | 스톡 테라퓨틱스, 인크. | 병태 및 질환 치료용 안티센스 올리고머 |
| JP2021523227A (ja) | 2018-05-04 | 2021-09-02 | ストーク セラピューティクス，インク． | コレステリルエステル蓄積症の処置のための方法及び組成物 |
| KR20210134003A (ko) | 2019-02-27 | 2021-11-08 | 스톡 테라퓨틱스, 인크. | 병태 및 질환의 치료를 위한 안티센스 올리고머 |
| US12338437B2 (en) | 2020-05-11 | 2025-06-24 | Stoke Therapeutics, Inc. | OPA1 antisense oligomers for treatment of conditions and diseases |
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| WO1994001550A1 (en) * | 1992-07-02 | 1994-01-20 | Hybridon, Inc. | Self-stabilized oligonucleotides as therapeutic agents |
| US6699843B2 (en) * | 1995-06-07 | 2004-03-02 | Gilead Sciences, Inc. | Method for treatment of tumors using nucleic acid ligands to PDGF |
| US6893844B1 (en) * | 1998-09-22 | 2005-05-17 | Long Yu | DNA encoding a new human hepatoma derived growth factor and producing method thereof |
| US20030198953A1 (en) | 2000-03-30 | 2003-10-23 | Spytek Kimberly A. | Novel proteins and nucleic acids encoding same |
| AU2003256857A1 (en) | 2002-08-08 | 2004-02-25 | Dharmacon, Inc. | Short interfering rnas having a hairpin structure containing a non-nucleotide loop |
| GB0321805D0 (en) | 2003-09-18 | 2003-10-15 | Univ Wales Medicine | Human tumour growth patterns |
| EP1526177A1 (en) | 2003-10-24 | 2005-04-27 | Institut Curie | Nucleic acids useful for triggering tumor cell lethality |
| WO2005111238A2 (en) * | 2004-04-19 | 2005-11-24 | Archemix Corporation | Aptamer-mediated intracellular delivery of therapeutic oligonucleotides |
| PT1768677E (pt) | 2004-07-02 | 2008-10-06 | Creabilis Therapeutics Spa | Ácidos nucleicos para o tratamento de patologias relacionadas com hmgb1 |
| JP2009508473A (ja) * | 2005-08-26 | 2009-03-05 | アーケミツクス・コーポレイシヨン | 高親和性でトロンビンに結合するアプタマー |
| WO2008054431A2 (en) | 2005-12-23 | 2008-05-08 | Board Of Regents Of The University Of Texas System | Anti-hyperproliferative therapies targeting hdgf |
| PL2135949T3 (pl) * | 2006-02-14 | 2013-03-29 | Noxxon Pharma Ag | Kwasy nukleinowe wiążące MCP-1 |
| US8367629B2 (en) * | 2006-02-14 | 2013-02-05 | Noxxon Pharma Ag | MCP-1 binding nucleic acids and use thereof |
| JP5380287B2 (ja) * | 2006-07-18 | 2014-01-08 | ノクソン・ファルマ・アクチエンゲゼルシャフト | Ｓｄｆ−１結合核酸 |
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- 2009-06-10 AU AU2009256906A patent/AU2009256906A1/en not_active Abandoned
Also Published As
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|---|---|
| JP2011524745A (ja) | 2011-09-08 |
| AU2009256906A1 (en) | 2009-12-17 |
| US20110190445A1 (en) | 2011-08-04 |
| JP5559159B2 (ja) | 2014-07-23 |
| WO2009149921A3 (en) | 2010-04-08 |
| WO2009149921A2 (en) | 2009-12-17 |
| WO2009149921A8 (en) | 2010-02-18 |
| EP2304031A2 (en) | 2011-04-06 |
| US8710021B2 (en) | 2014-04-29 |
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Effective date: 20150610 |