CA2727285A1 - Inhibition of hrp-3 using modified oligonucleotides - Google Patents
Inhibition of hrp-3 using modified oligonucleotides Download PDFInfo
- Publication number
- CA2727285A1 CA2727285A1 CA2727285A CA2727285A CA2727285A1 CA 2727285 A1 CA2727285 A1 CA 2727285A1 CA 2727285 A CA2727285 A CA 2727285A CA 2727285 A CA2727285 A CA 2727285A CA 2727285 A1 CA2727285 A1 CA 2727285A1
- Authority
- CA
- Canada
- Prior art keywords
- hrp
- building blocks
- oligonucleotide molecule
- nucleotide
- oligonucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- C12N2310/00—Structure or type of the nucleic acid
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US6057108P | 2008-06-11 | 2008-06-11 | |
| US61/060,571 | 2008-06-11 | ||
| PCT/EP2009/004186 WO2009149921A2 (en) | 2008-06-11 | 2009-06-10 | Inhibition of hrp-3 using modified oligonucleotides |
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| CA2727285A1 true CA2727285A1 (en) | 2009-12-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CA2727285A Abandoned CA2727285A1 (en) | 2008-06-11 | 2009-06-10 | Inhibition of hrp-3 using modified oligonucleotides |
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| EP (1) | EP2304031A2 (enExample) |
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| AU (1) | AU2009256906A1 (enExample) |
| CA (1) | CA2727285A1 (enExample) |
| WO (1) | WO2009149921A2 (enExample) |
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| WO2011130371A1 (en) | 2010-04-13 | 2011-10-20 | Life Technologies Corporation | Compositions and methods for inhibition of nucleic acids function |
| WO2015046783A1 (en) * | 2013-09-30 | 2015-04-02 | Korea Institute Of Radiological & Medical Sciences | Pharmaceutical composition for treatment of radiation- or drug-resistant cancer comprising hrp-3 inhibitor |
| GB201410693D0 (en) | 2014-06-16 | 2014-07-30 | Univ Southampton | Splicing modulation |
| CA2963288A1 (en) | 2014-10-03 | 2016-04-07 | Cold Spring Harbor Laboratory | Targeted augmentation of nuclear gene output |
| AU2016334804B2 (en) | 2015-10-09 | 2022-03-31 | University Of Southampton | Modulation of gene expression and screening for deregulated protein expression |
| WO2017106377A1 (en) | 2015-12-14 | 2017-06-22 | Cold Spring Harbor Laboratory | Antisense oligomers for treatment of autosomal dominant mental retardation-5 and dravet syndrome |
| US11096956B2 (en) | 2015-12-14 | 2021-08-24 | Stoke Therapeutics, Inc. | Antisense oligomers and uses thereof |
| LT3673080T (lt) | 2017-08-25 | 2023-12-27 | Stoke Therapeutics, Inc. | Priešprasminiai oligomerai, skirti būklėms ir ligoms gydyti |
| BR112020022512A2 (pt) | 2018-05-04 | 2021-05-04 | Stoke Therapeutics, Inc. | métodos e composições para tratamento de doença de armazenamento de éster de colesteril |
| EP4150092A4 (en) | 2020-05-11 | 2024-11-06 | Stoke Therapeutics, Inc. | OPA1 ANTISENSE OLIGOMERS FOR THE TREATMENT OF DISEASES AND CONDITIONS |
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| JPH08501928A (ja) * | 1992-07-02 | 1996-03-05 | ハイブライドン インコーポレイテッド | 治療剤としての自己安定化オリゴヌクレオチド |
| US6699843B2 (en) * | 1995-06-07 | 2004-03-02 | Gilead Sciences, Inc. | Method for treatment of tumors using nucleic acid ligands to PDGF |
| US6893844B1 (en) * | 1998-09-22 | 2005-05-17 | Long Yu | DNA encoding a new human hepatoma derived growth factor and producing method thereof |
| US20030198953A1 (en) | 2000-03-30 | 2003-10-23 | Spytek Kimberly A. | Novel proteins and nucleic acids encoding same |
| US20040058886A1 (en) | 2002-08-08 | 2004-03-25 | Dharmacon, Inc. | Short interfering RNAs having a hairpin structure containing a non-nucleotide loop |
| GB0321805D0 (en) | 2003-09-18 | 2003-10-15 | Univ Wales Medicine | Human tumour growth patterns |
| EP1526177A1 (en) * | 2003-10-24 | 2005-04-27 | Institut Curie | Nucleic acids useful for triggering tumor cell lethality |
| US20060105975A1 (en) * | 2004-04-19 | 2006-05-18 | Shannon Pendergrast | Aptamer-mediated intracellular delivery of therapeutic oligonucleotides |
| US20080305073A1 (en) * | 2004-07-02 | 2008-12-11 | Barone Domenico G | Therapeutic Agents for the Treatment of Hmgb1-Related Pathologies |
| RS20080075A (sr) * | 2005-08-26 | 2009-07-15 | Archemix Corp., | Aptameri koji vezuju trombin sa visokim afinitetom |
| EP1978985A2 (en) * | 2005-12-23 | 2008-10-15 | Board Of Regents Of The University Of Texas System | Anti-hyperproliferative therapies targeting hdgf |
| EP2135949B1 (en) * | 2006-02-14 | 2012-10-17 | Noxxon Pharma AG | MCP-1 binding nucleic acids |
| US8367629B2 (en) * | 2006-02-14 | 2013-02-05 | Noxxon Pharma Ag | MCP-1 binding nucleic acids and use thereof |
| AR061929A1 (es) * | 2006-07-18 | 2008-10-01 | Noxxon Pharma Ag | Acidos nucleicos de union al factor derivado de celulas estomales sdf-1 |
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Also Published As
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| US20110190445A1 (en) | 2011-08-04 |
| WO2009149921A3 (en) | 2010-04-08 |
| EP2304031A2 (en) | 2011-04-06 |
| US8710021B2 (en) | 2014-04-29 |
| WO2009149921A2 (en) | 2009-12-17 |
| JP5559159B2 (ja) | 2014-07-23 |
| WO2009149921A8 (en) | 2010-02-18 |
| AU2009256906A1 (en) | 2009-12-17 |
| JP2011524745A (ja) | 2011-09-08 |
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