JP5559159B2 - 修飾オリゴヌクレオチドを使用するｈｒｐ−３の阻害 - Google Patents
修飾オリゴヌクレオチドを使用するｈｒｐ−３の阻害 Download PDFInfo
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- JP5559159B2 JP5559159B2 JP2011512892A JP2011512892A JP5559159B2 JP 5559159 B2 JP5559159 B2 JP 5559159B2 JP 2011512892 A JP2011512892 A JP 2011512892A JP 2011512892 A JP2011512892 A JP 2011512892A JP 5559159 B2 JP5559159 B2 JP 5559159B2
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6057108P | 2008-06-11 | 2008-06-11 | |
| US61/060,571 | 2008-06-11 | ||
| PCT/EP2009/004186 WO2009149921A2 (en) | 2008-06-11 | 2009-06-10 | Inhibition of hrp-3 using modified oligonucleotides |
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| Publication Number | Publication Date |
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| JP2011524745A JP2011524745A (ja) | 2011-09-08 |
| JP2011524745A5 JP2011524745A5 (enExample) | 2012-07-12 |
| JP5559159B2 true JP5559159B2 (ja) | 2014-07-23 |
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| JP2011512892A Expired - Fee Related JP5559159B2 (ja) | 2008-06-11 | 2009-06-10 | 修飾オリゴヌクレオチドを使用するｈｒｐ−３の阻害 |
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| EP (1) | EP2304031A2 (enExample) |
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| WO2011130371A1 (en) | 2010-04-13 | 2011-10-20 | Life Technologies Corporation | Compositions and methods for inhibition of nucleic acids function |
| US9963701B2 (en) | 2013-09-30 | 2018-05-08 | Korea Institute Of Radiological & Medical Sciences | Pharmaceutical composition for treatment of radiation- or drug-resistant cancer comprising HRP-3 inhibitor |
| GB201410693D0 (en) | 2014-06-16 | 2014-07-30 | Univ Southampton | Splicing modulation |
| EP3201339A4 (en) | 2014-10-03 | 2018-09-19 | Cold Spring Harbor Laboratory | Targeted augmentation of nuclear gene output |
| KR102422625B1 (ko) | 2015-10-09 | 2022-07-20 | 유니버시티 오브 사우스앰톤 | 유전자 발현의 조절 및 탈조절된 단백질 발현의 스크리닝 |
| US11096956B2 (en) | 2015-12-14 | 2021-08-24 | Stoke Therapeutics, Inc. | Antisense oligomers and uses thereof |
| KR102604132B1 (ko) | 2015-12-14 | 2023-11-17 | 콜드스프링하버러보러토리 | 상염색체 우성 정신 지체 5 및 드라베 증후군의 치료를 위한 안티센스 올리고머 |
| SG11202001590RA (en) | 2017-08-25 | 2020-03-30 | Stoke Therapeutics Inc | Antisense oligomers for treatment of conditions and diseases |
| EP3788169A4 (en) | 2018-05-04 | 2022-08-10 | Stoke Therapeutics, Inc. | Methods and compositions for treatment of cholesteryl ester storage disease |
| MX2022014151A (es) | 2020-05-11 | 2022-11-30 | Stoke Therapeutics Inc | Oligomeros antisentido de opa1 para tratamiento de afecciones y enfermedades. |
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| AU4770093A (en) * | 1992-07-02 | 1994-01-31 | Hybridon, Inc. | Self-stabilized oligonucleotides as therapeutic agents |
| US6699843B2 (en) * | 1995-06-07 | 2004-03-02 | Gilead Sciences, Inc. | Method for treatment of tumors using nucleic acid ligands to PDGF |
| US6893844B1 (en) * | 1998-09-22 | 2005-05-17 | Long Yu | DNA encoding a new human hepatoma derived growth factor and producing method thereof |
| US20030198953A1 (en) | 2000-03-30 | 2003-10-23 | Spytek Kimberly A. | Novel proteins and nucleic acids encoding same |
| US20040058886A1 (en) * | 2002-08-08 | 2004-03-25 | Dharmacon, Inc. | Short interfering RNAs having a hairpin structure containing a non-nucleotide loop |
| GB0321805D0 (en) | 2003-09-18 | 2003-10-15 | Univ Wales Medicine | Human tumour growth patterns |
| EP1526177A1 (en) * | 2003-10-24 | 2005-04-27 | Institut Curie | Nucleic acids useful for triggering tumor cell lethality |
| US20060105975A1 (en) * | 2004-04-19 | 2006-05-18 | Shannon Pendergrast | Aptamer-mediated intracellular delivery of therapeutic oligonucleotides |
| PT1768677E (pt) | 2004-07-02 | 2008-10-06 | Creabilis Therapeutics Spa | Ácidos nucleicos para o tratamento de patologias relacionadas com hmgb1 |
| MEP0208A (xx) * | 2005-08-26 | 2010-02-10 | Archemix Corp | Aptameri koji vezuje trombin sa visokim afininitetom |
| CA2634783A1 (en) * | 2005-12-23 | 2008-05-08 | Board Of Regents Of The University Of Texas System | Anti-hyperproliferative therapies targeting hdgf |
| WO2007093409A2 (en) * | 2006-02-14 | 2007-08-23 | Noxxon Pharma Ag | Mcp-i binding nucleic acids |
| US8367629B2 (en) * | 2006-02-14 | 2013-02-05 | Noxxon Pharma Ag | MCP-1 binding nucleic acids and use thereof |
| MX2009000656A (es) * | 2006-07-18 | 2009-03-25 | Noxxon Pharma Ag | Acidos nucleicos que se fijan a sdf-i. |
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- 2009-06-10 CA CA2727285A patent/CA2727285A1/en not_active Abandoned
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| JP2011524745A (ja) | 2011-09-08 |
| WO2009149921A2 (en) | 2009-12-17 |
| US8710021B2 (en) | 2014-04-29 |
| EP2304031A2 (en) | 2011-04-06 |
| WO2009149921A3 (en) | 2010-04-08 |
| US20110190445A1 (en) | 2011-08-04 |
| AU2009256906A1 (en) | 2009-12-17 |
| WO2009149921A8 (en) | 2010-02-18 |
| CA2727285A1 (en) | 2009-12-17 |
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