CA2681302C - Proliposomal and liposomal compositions of poorly water-soluble compounds - Google Patents
Proliposomal and liposomal compositions of poorly water-soluble compounds Download PDFInfo
- Publication number
- CA2681302C CA2681302C CA2681302A CA2681302A CA2681302C CA 2681302 C CA2681302 C CA 2681302C CA 2681302 A CA2681302 A CA 2681302A CA 2681302 A CA2681302 A CA 2681302A CA 2681302 C CA2681302 C CA 2681302C
- Authority
- CA
- Canada
- Prior art keywords
- composition
- proliposomal
- docetaxel
- solution
- liposomal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN590DE2007 | 2007-03-19 | ||
IN590/DEL/2007 | 2007-03-19 | ||
PCT/IN2008/000003 WO2008114274A1 (en) | 2007-03-19 | 2008-01-04 | Proliposomal and liposomal compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2681302A1 CA2681302A1 (en) | 2008-09-25 |
CA2681302C true CA2681302C (en) | 2013-07-23 |
Family
ID=39620132
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2681302A Expired - Fee Related CA2681302C (en) | 2007-03-19 | 2008-01-04 | Proliposomal and liposomal compositions of poorly water-soluble compounds |
Country Status (8)
Country | Link |
---|---|
US (1) | US20090017105A1 (es) |
EP (1) | EP2146692A1 (es) |
AR (1) | AR065805A1 (es) |
AU (1) | AU2008227852B2 (es) |
CA (1) | CA2681302C (es) |
CL (1) | CL2008000786A1 (es) |
TW (1) | TWI355946B (es) |
WO (1) | WO2008114274A1 (es) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8476010B2 (en) | 2003-07-10 | 2013-07-02 | App Pharmaceuticals Llc | Propofol formulations with non-reactive container closures |
US20140335166A1 (en) * | 2013-05-08 | 2014-11-13 | Michael W. Fountain | Methods of Making and Using Nano Scale Particles |
KR101066197B1 (ko) * | 2009-04-06 | 2011-09-20 | 한국생명공학연구원 | 코엔자임 q10 나노입자, 그 제조방법 및 상기 나노입자를 포함하는 조성물 |
PL214538B1 (pl) * | 2009-05-28 | 2013-08-30 | P P F Hasco Lek Spolka Akcyjna | Kompozycja liposomowa zawierajaca naproksen i sposób wytwarzania kompozycji liposomowej zawierajacej naproksen |
US9402812B2 (en) * | 2009-09-23 | 2016-08-02 | Indu JAVERI | Methods for the preparation of liposomes |
US10143652B2 (en) | 2009-09-23 | 2018-12-04 | Curirx Inc. | Methods for the preparation of liposomes |
RU2526114C2 (ru) | 2009-12-03 | 2014-08-20 | Цзянсу Хэнжуй Медицин Ко., Лтд. | Липосомы иринотекана или его солей, способ их получения |
MX341082B (es) | 2010-05-03 | 2016-08-08 | Teikoku Pharma Usa Inc | Formulaciones de pro-emulsion de taxano no acuosas y metodos para hacer y usar las mismas. |
WO2013170012A2 (en) * | 2012-05-09 | 2013-11-14 | Western University Of Health Sciences | Proliposomal testosterone formulations |
CA2871820C (en) * | 2012-05-10 | 2020-11-03 | Painreform Ltd. | Depot formulations of a hydrophobic active ingredient and methods for preparation thereof |
JO3685B1 (ar) | 2012-10-01 | 2020-08-27 | Teikoku Pharma Usa Inc | صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها |
CN103768018A (zh) * | 2012-10-17 | 2014-05-07 | 南京绿叶思科药业有限公司 | 一种卡巴他赛脂质体注射剂及其制备方法 |
US20150132369A1 (en) * | 2013-11-09 | 2015-05-14 | Exir Nano Sina Company | Nanoliposomal cyclosorin formulations for immunosuppresion and methods for the production thereof |
CN107530283A (zh) * | 2015-03-03 | 2018-01-02 | 奎尔波特股份有限公司 | 组合脂质体药物制剂 |
JP2018507227A (ja) * | 2015-03-03 | 2018-03-15 | キュアポート インコーポレイテッド | 二薬搭載リポソーム医薬製剤 |
CA2992789A1 (en) | 2015-08-20 | 2017-02-23 | Ipsen Biopharm Ltd. | Combination therapy using liposomal irinotecan and a parp inhibitor for cancer treatment |
CN105055322A (zh) * | 2015-09-02 | 2015-11-18 | 厦门市壳聚糖生物科技有限公司 | 甲氨喋呤磷脂复合物、其纳米粒子及其靶向缓释制剂三者的制备方法 |
EP3360577A4 (en) * | 2015-10-07 | 2019-06-12 | Ensuiko Sugar Refining Co., Ltd. | LIPOSOME COMPRISING A TAXANE COMPOUND |
KR20180101452A (ko) * | 2016-01-08 | 2018-09-12 | 웨스턴 유니버시티 오브 헬스 사이언시스 | 프로리포솜성 테스토스테론 운데카노에이트 제제 |
CN107362142B (zh) * | 2016-05-13 | 2023-04-25 | 山东新时代药业有限公司 | 一种氟维司群脂质体注射液及其制备方法 |
MX2019002733A (es) | 2016-09-09 | 2019-08-29 | Irisys Inc | Composiciones anticancerígenas liposomales. |
ES2923929T3 (es) | 2016-10-28 | 2022-10-03 | Servier Lab | Formulación liposomal para uso en el tratamiento del cáncer |
NZ753214A (en) * | 2016-11-11 | 2022-02-25 | Univ Western Health Sciences | Methods of treating upper tract urothelial carcinomas |
CN108926533B (zh) * | 2017-05-24 | 2022-03-25 | 江苏天士力帝益药业有限公司 | 一种替西罗莫司脂质体及其制备方法 |
WO2019082139A1 (en) * | 2017-10-27 | 2019-05-02 | Shilpa Medicare Limited | LIPOSOMAL FINGOLIMOD HYDROCHLORIDE INJECTION |
CN111372570A (zh) * | 2017-11-30 | 2020-07-03 | 希尔帕医疗保健有限公司 | 高载药量的多西他赛脂质体注射组合物 |
CN110368500B (zh) * | 2019-07-12 | 2020-06-30 | 浙江大学 | 一种两亲性共聚物药物前体、制备方法以及包载钙泊三醇的纳米颗粒 |
CN112076158B (zh) * | 2020-08-28 | 2023-12-08 | 西南民族大学 | 一种治疗慢性肾炎的脂质体-纳米粒复合体 |
CN113181113A (zh) * | 2021-04-28 | 2021-07-30 | 四川科伦药业股份有限公司 | 一种甲硝唑氯化钠注射液的制备方法 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4744989A (en) * | 1984-02-08 | 1988-05-17 | E. R. Squibb & Sons, Inc. | Method of preparing liposomes and products produced thereby |
EP0158441B2 (en) * | 1984-03-08 | 2001-04-04 | Phares Pharmaceutical Research N.V. | Liposome-forming composition |
US4837028A (en) * | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
US5262168A (en) * | 1987-05-22 | 1993-11-16 | The Liposome Company, Inc. | Prostaglandin-lipid formulations |
DE69026820T2 (de) * | 1989-03-31 | 1996-11-28 | Univ California | Zubereitung von liposomen- und lipid-komplexzusammensetzungen |
US5013556A (en) * | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
US5498420A (en) * | 1991-04-12 | 1996-03-12 | Merz & Co. Gmbh & Co. | Stable small particle liposome preparations, their production and use in topical cosmetic, and pharmaceutical compositions |
JP3479535B2 (ja) * | 1993-07-08 | 2003-12-15 | ザ リポソーム カンパニー、インコーポレーテッド | リポソームの粒径を制御する方法 |
SA95160463B1 (ar) * | 1994-12-22 | 2005-10-04 | استرا أكتيبولاج | مساحيق للاستنشاق |
US5753262A (en) * | 1995-06-07 | 1998-05-19 | Aronex Pharmaceuticals, Inc. | Cationic lipid acid salt of 3beta N- (N', N'-dimethylaminoethane) - carbamoyl!cholestrol and halogenated solvent-free preliposomal lyophilate thereof |
GB2331924A (en) * | 1997-12-08 | 1999-06-09 | Phares Pharm Res Nv | Lipid compositions and their use |
EP1217989B1 (en) * | 1999-10-01 | 2005-12-14 | Lipoxen Technologies Limited | Vaccines for oral use which contain liposome-entrapped dna |
US6761901B1 (en) * | 2000-05-02 | 2004-07-13 | Enzrel Inc. | Liposome drug delivery |
AU2003280505B2 (en) * | 2002-06-26 | 2009-01-15 | Syncore Biotechnology Co., Ltd | Method of producing a cationic liposomal preparation comprising a lipophilic compound |
AU2003298738A1 (en) * | 2002-11-26 | 2004-06-18 | Su-Ming Chiang | Liposomal formulations |
KR20050105455A (ko) * | 2003-02-11 | 2005-11-04 | 네오팜 인코포레이티드 | 리포좀 제제의 제조 방법 |
US7696359B2 (en) * | 2003-09-03 | 2010-04-13 | Kyowa Hakko Kirin Co., Ltd. | Compound modified with glycerol derivative |
KR101376895B1 (ko) * | 2004-05-03 | 2014-03-25 | 헤르메스 바이오사이언스, 인코포레이티드 | 약물 전달에 유용한 리포좀 |
BRPI0619565A2 (pt) * | 2005-12-08 | 2011-10-04 | Wyeth Corp | composições lipossÈmicas |
US9814672B2 (en) * | 2007-03-09 | 2017-11-14 | Susan T. Laing | Echogenic vehicle for clinical delivery of plasminogen activator and other fibrin-binding therapeutics to thrombi |
-
2008
- 2008-01-04 WO PCT/IN2008/000003 patent/WO2008114274A1/en active Search and Examination
- 2008-01-04 AU AU2008227852A patent/AU2008227852B2/en not_active Ceased
- 2008-01-04 CA CA2681302A patent/CA2681302C/en not_active Expired - Fee Related
- 2008-01-04 EP EP08702731A patent/EP2146692A1/en not_active Withdrawn
- 2008-03-10 TW TW097108323A patent/TWI355946B/zh not_active IP Right Cessation
- 2008-03-11 US US12/045,958 patent/US20090017105A1/en not_active Abandoned
- 2008-03-18 CL CL200800786A patent/CL2008000786A1/es unknown
- 2008-03-19 AR ARP080101166A patent/AR065805A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
AU2008227852A1 (en) | 2008-09-25 |
US20090017105A1 (en) | 2009-01-15 |
WO2008114274A1 (en) | 2008-09-25 |
TW200904483A (en) | 2009-02-01 |
AR065805A1 (es) | 2009-07-01 |
AU2008227852B2 (en) | 2011-02-24 |
CL2008000786A1 (es) | 2008-09-26 |
CA2681302A1 (en) | 2008-09-25 |
TWI355946B (en) | 2012-01-11 |
EP2146692A1 (en) | 2010-01-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20160104 |