CA2677771A1 - Method for cloning cognate antibodies - Google Patents

Method for cloning cognate antibodies Download PDF

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Publication number
CA2677771A1
CA2677771A1 CA002677771A CA2677771A CA2677771A1 CA 2677771 A1 CA2677771 A1 CA 2677771A1 CA 002677771 A CA002677771 A CA 002677771A CA 2677771 A CA2677771 A CA 2677771A CA 2677771 A1 CA2677771 A1 CA 2677771A1
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CA
Canada
Prior art keywords
cells
multiplex
variable region
sequences
primer
Prior art date
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Abandoned
Application number
CA002677771A
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English (en)
French (fr)
Inventor
Per-Johan Meijer
Lars Soegaard Nielsen
Jesper Kastrup
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Symphogen AS
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Individual
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Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38561767&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2677771(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CA2677771A1 publication Critical patent/CA2677771A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/005—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1282—Clostridium (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA002677771A 2007-03-01 2008-02-27 Method for cloning cognate antibodies Abandoned CA2677771A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200700316 2007-03-01
DKPA200700316 2007-03-01
US90477207P 2007-03-05 2007-03-05
US60/904,772 2007-03-05
PCT/DK2008/050048 WO2008104184A2 (en) 2007-03-01 2008-02-27 Method for cloning cognate antibodies

Publications (1)

Publication Number Publication Date
CA2677771A1 true CA2677771A1 (en) 2008-09-04

Family

ID=38561767

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002677771A Abandoned CA2677771A1 (en) 2007-03-01 2008-02-27 Method for cloning cognate antibodies

Country Status (23)

Country Link
US (2) US8283294B2 (https=)
EP (1) EP2121920B1 (https=)
JP (1) JP5669397B2 (https=)
KR (1) KR20090118993A (https=)
CN (1) CN101622346A (https=)
AT (1) ATE521704T1 (https=)
AU (1) AU2008221119B2 (https=)
BR (1) BRPI0808171A2 (https=)
CA (1) CA2677771A1 (https=)
CY (1) CY1112664T1 (https=)
DK (1) DK2121920T3 (https=)
ES (1) ES2369946T3 (https=)
HR (1) HRP20110686T1 (https=)
IL (1) IL199773A0 (https=)
MX (1) MX2009008908A (https=)
NZ (1) NZ578851A (https=)
PL (1) PL2121920T3 (https=)
PT (1) PT2121920E (https=)
RU (1) RU2459868C2 (https=)
SI (1) SI2121920T1 (https=)
TW (1) TW200911986A (https=)
WO (1) WO2008104184A2 (https=)
ZA (1) ZA200905831B (https=)

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BRPI0808171A2 (pt) 2014-08-05
HK1133905A1 (en) 2010-04-09
JP2010535150A (ja) 2010-11-18
CN101622346A (zh) 2010-01-06
WO2008104184A2 (en) 2008-09-04
ZA200905831B (en) 2011-02-23
AU2008221119A1 (en) 2008-09-04
KR20090118993A (ko) 2009-11-18
JP5669397B2 (ja) 2015-02-12
US8283294B2 (en) 2012-10-09
SI2121920T1 (sl) 2011-12-30
US20130023447A1 (en) 2013-01-24
IL199773A0 (en) 2010-04-15
US20080227660A1 (en) 2008-09-18
EP2121920A2 (en) 2009-11-25
AU2008221119B2 (en) 2013-11-14
PL2121920T3 (pl) 2012-01-31
NZ578851A (en) 2011-09-30
EP2121920B1 (en) 2011-08-24
MX2009008908A (es) 2009-08-28
ES2369946T3 (es) 2011-12-09
WO2008104184A3 (en) 2008-10-16
PT2121920E (pt) 2011-10-03
RU2459868C2 (ru) 2012-08-27
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ATE521704T1 (de) 2011-09-15
TW200911986A (en) 2009-03-16

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