CA2674238A1 - Targeting nbs1-atm interaction to sensitize cancer cells to radiotherapy and chemotherapy - Google Patents
Targeting nbs1-atm interaction to sensitize cancer cells to radiotherapy and chemotherapy Download PDFInfo
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- CA2674238A1 CA2674238A1 CA002674238A CA2674238A CA2674238A1 CA 2674238 A1 CA2674238 A1 CA 2674238A1 CA 002674238 A CA002674238 A CA 002674238A CA 2674238 A CA2674238 A CA 2674238A CA 2674238 A1 CA2674238 A1 CA 2674238A1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
- C07K14/43—Sweetening agents, e.g. thaumatin, monellin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
Landscapes
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- Chemical & Material Sciences (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86345706P | 2006-10-30 | 2006-10-30 | |
| US60/863,457 | 2006-10-30 | ||
| PCT/US2007/022886 WO2008054726A2 (en) | 2006-10-30 | 2007-10-30 | Targeting nbs1-atm interaction to sensitize cancer cells to radiotherapy and chemotherapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2674238A1 true CA2674238A1 (en) | 2008-05-08 |
Family
ID=39344878
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002674238A Abandoned CA2674238A1 (en) | 2006-10-30 | 2007-10-30 | Targeting nbs1-atm interaction to sensitize cancer cells to radiotherapy and chemotherapy |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20100120679A1 (enExample) |
| EP (1) | EP2091964A2 (enExample) |
| JP (1) | JP2010508022A (enExample) |
| KR (1) | KR20090102744A (enExample) |
| CN (1) | CN101631799A (enExample) |
| AU (1) | AU2007314366A1 (enExample) |
| CA (1) | CA2674238A1 (enExample) |
| MX (1) | MX2009004748A (enExample) |
| WO (1) | WO2008054726A2 (enExample) |
Families Citing this family (27)
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| US8118754B1 (en) | 2007-11-15 | 2012-02-21 | Flynn Edward R | Magnetic needle biopsy |
| US9964469B2 (en) | 2005-02-28 | 2018-05-08 | Imagion Biosystems, Inc. | Magnetic needle separation and optical monitoring |
| US8841414B1 (en) * | 2006-01-27 | 2014-09-23 | University Of Mississippi Medical Center | Targeted delivery of therapeutic peptides by thermally responsive biopolymers |
| US8447379B2 (en) | 2006-11-16 | 2013-05-21 | Senior Scientific, LLC | Detection, measurement, and imaging of cells such as cancer and other biologic substances using targeted nanoparticles and magnetic properties thereof |
| US10194825B2 (en) | 2009-11-06 | 2019-02-05 | Imagion Biosystems Inc. | Methods and apparatuses for the localization and treatment of disease such as cancer |
| EP2496175A4 (en) | 2009-11-06 | 2014-08-06 | Scient Nanomedicine Inc | DETECTION, MEASUREMENT, AND IMAGING OF (eg, CANCER) CELLS AND OTHER BIOLOGICAL SUBSTANCES USING TARGETED NANOPARTICLES AND THEIR MAGNETIC PROPERTIES |
| JP6081447B2 (ja) * | 2011-04-29 | 2017-02-15 | オーフス ユニバーシティAarhus Universitet | 癌における臨床的に関連する低酸素症を判定する方法 |
| WO2013098339A1 (en) * | 2011-12-27 | 2013-07-04 | Universite Pierre Et Marie Curie (Paris 6) | Anti-tumor adjuvant therapy |
| GB201209517D0 (en) * | 2012-05-29 | 2012-07-11 | Univ Birmingham | Nanoparticles |
| CN104046644A (zh) * | 2013-03-14 | 2014-09-17 | 中国科学院上海生命科学研究院 | 人源化小鼠模型的构建方法和应用 |
| KR101447901B1 (ko) * | 2013-04-16 | 2014-10-16 | 한양대학교 산학협력단 | 지방세포 표적 비바이러스성 유전자 전달체 |
| CN106029172B (zh) * | 2014-02-27 | 2019-12-24 | 皇家飞利浦有限公司 | 用于高剂量率短距离放射治疗的医学仪器 |
| US10213284B2 (en) | 2015-06-30 | 2019-02-26 | Tela Bio, Inc. | Corner-lock stitch patterns |
| WO2017015421A1 (en) | 2015-07-21 | 2017-01-26 | Tela Bio, Inc. | Compliance control stitching in substrate materials |
| US9820843B2 (en) | 2016-04-26 | 2017-11-21 | Tela Bio, Inc. | Hernia repair grafts having anti-adhesion barriers |
| KR101875111B1 (ko) * | 2016-04-29 | 2018-07-09 | 한국수력원자력 주식회사 | 저선량 방사선을 이용한 암화유전자 Ras-유도 악성 암화 억제 |
| MX2019009753A (es) * | 2017-02-16 | 2019-12-18 | Firststring Res Inc | Composicion y metodos para prevenir lesion por radiacion y promover la regeneracion de tejidos. |
| WO2018195434A1 (en) | 2017-04-21 | 2018-10-25 | Lisanti Michael P | Vitamin c and doxycycline: a synthetic lethal combination therapy for eradicating cancer stem cells (cscs) |
| EP3612177A4 (en) | 2017-04-21 | 2021-01-13 | Lunella Biotech, Inc. | TARGETING HYPOXIC CARCINOUS STEM CELLS (SCC) USING DOXYCYCLINE: IMPLICATIONS FOR IMPROVING ANTI-ANGIOGENIC THERAPY |
| CA3063717C (en) | 2017-05-19 | 2021-08-24 | Lunella Biotech, Inc. | Antimitoscins: targeted inhibitors of mitochondrial biogenesis for eradicating cancer stem cells |
| WO2018213764A1 (en) | 2017-05-19 | 2018-11-22 | Lunella Biotech, Inc. | Companion diagnostics for mitochondrial inhibitors |
| BR112019026097A2 (pt) | 2017-06-26 | 2020-07-07 | Lunella Biotech, Inc. | mitoketoscins: terapêuticos à base de mitocôndrias com direcionamento no metabolismo da cetona em células cancerígenas |
| WO2019173792A1 (en) * | 2018-03-09 | 2019-09-12 | Tela Bio, Inc. | Surgical repair graft |
| EP4585235A3 (en) | 2019-03-08 | 2025-08-20 | Tela Bio, Inc. | Textured medical textiles |
| US20240335575A1 (en) * | 2021-10-20 | 2024-10-10 | Aphios Corporation | Method and apparatus for inactivating pathogens in units of whole blood using superparamagnetic nanoparticles coated with chemiluminescence reagents and broad-spectrum anti-viral therapeutics |
| CN115300449B (zh) * | 2022-02-07 | 2023-06-27 | 郑州大学第一附属医院 | 榄香烯在制备抑制肿瘤耐药性的控释制剂中的应用 |
| CN118126155B (zh) * | 2024-02-05 | 2025-04-25 | 中山大学附属第七医院(深圳) | 一种人nbs1蛋白赖氨酸388位点乳酸化抗原、抗体及其制备方法与应用 |
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|---|---|---|---|---|
| US6077880A (en) * | 1997-08-08 | 2000-06-20 | Cordis Corporation | Highly radiopaque polyolefins and method for making the same |
| US7122343B1 (en) * | 1998-04-27 | 2006-10-17 | Wisconsin Alumni Research Foundation | Methods to alter levels of a DNA repair protein |
| US7074902B1 (en) * | 1998-04-27 | 2006-07-11 | Warf Wisconsin Alumni Research Foundation | Antibody specific for a DNA repair protein |
| US6530944B2 (en) * | 2000-02-08 | 2003-03-11 | Rice University | Optically-active nanoparticles for use in therapeutic and diagnostic methods |
| US20030104427A1 (en) * | 2001-06-25 | 2003-06-05 | Petrini John H.J. | Methods to modulate telomere structure and function |
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2007
- 2007-10-30 MX MX2009004748A patent/MX2009004748A/es not_active Application Discontinuation
- 2007-10-30 EP EP07867306A patent/EP2091964A2/en not_active Withdrawn
- 2007-10-30 WO PCT/US2007/022886 patent/WO2008054726A2/en not_active Ceased
- 2007-10-30 JP JP2009534698A patent/JP2010508022A/ja not_active Withdrawn
- 2007-10-30 KR KR1020097011353A patent/KR20090102744A/ko not_active Withdrawn
- 2007-10-30 US US12/447,717 patent/US20100120679A1/en not_active Abandoned
- 2007-10-30 CN CN200780048001A patent/CN101631799A/zh active Pending
- 2007-10-30 CA CA002674238A patent/CA2674238A1/en not_active Abandoned
- 2007-10-30 AU AU2007314366A patent/AU2007314366A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20090102744A (ko) | 2009-09-30 |
| EP2091964A2 (en) | 2009-08-26 |
| WO2008054726A2 (en) | 2008-05-08 |
| CN101631799A (zh) | 2010-01-20 |
| WO2008054726A3 (en) | 2009-02-05 |
| US20100120679A1 (en) | 2010-05-13 |
| MX2009004748A (es) | 2009-08-25 |
| JP2010508022A (ja) | 2010-03-18 |
| AU2007314366A1 (en) | 2008-05-08 |
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