CA2645358C - Humanized monoclonal antibodies to hepatocyte growth factor - Google Patents
Humanized monoclonal antibodies to hepatocyte growth factor Download PDFInfo
- Publication number
- CA2645358C CA2645358C CA2645358A CA2645358A CA2645358C CA 2645358 C CA2645358 C CA 2645358C CA 2645358 A CA2645358 A CA 2645358A CA 2645358 A CA2645358 A CA 2645358A CA 2645358 C CA2645358 C CA 2645358C
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- Prior art keywords
- ser
- thr
- gly
- mab
- val
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
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- General Health & Medical Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78824306P | 2006-04-01 | 2006-04-01 | |
| US60/788,243 | 2006-04-01 | ||
| PCT/US2007/065385 WO2007115049A2 (en) | 2006-04-01 | 2007-03-28 | Humanized monoclonal antibodies to hepatocyte growth factor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2645358A1 CA2645358A1 (en) | 2007-10-11 |
| CA2645358C true CA2645358C (en) | 2015-05-05 |
Family
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2007
- 2007-03-16 AR ARP070101084A patent/AR059922A1/es not_active Application Discontinuation
- 2007-03-26 PE PE2007000342A patent/PE20080008A1/es not_active Application Discontinuation
- 2007-03-28 ZA ZA200807903A patent/ZA200807903B/xx unknown
- 2007-03-28 UA UAA200812789A patent/UA94452C2/ru unknown
- 2007-03-28 GE GEAP200710944A patent/GEP20125517B/en unknown
- 2007-03-28 CN CN2012105645795A patent/CN103172736A/zh active Pending
- 2007-03-28 EP EP07759598.1A patent/EP2016162B1/en active Active
- 2007-03-28 MX MX2008012619A patent/MX2008012619A/es active IP Right Grant
- 2007-03-28 WO PCT/US2007/065385 patent/WO2007115049A2/en not_active Ceased
- 2007-03-28 NZ NZ571132A patent/NZ571132A/en not_active IP Right Cessation
- 2007-03-28 KR KR1020087026853A patent/KR101516289B1/ko not_active Expired - Fee Related
- 2007-03-28 EP EP11192887A patent/EP2476704A3/en not_active Withdrawn
- 2007-03-28 JP JP2009503254A patent/JP5312315B2/ja not_active Expired - Fee Related
- 2007-03-28 RU RU2008143318/10A patent/RU2461570C2/ru not_active IP Right Cessation
- 2007-03-28 CN CN2007800123673A patent/CN101415811B/zh not_active Expired - Fee Related
- 2007-03-28 CA CA2645358A patent/CA2645358C/en not_active Expired - Fee Related
- 2007-03-28 BR BRPI0709932-0A patent/BRPI0709932A2/pt not_active IP Right Cessation
- 2007-03-28 AU AU2007233242A patent/AU2007233242B2/en not_active Ceased
- 2007-03-28 ES ES07759598.1T patent/ES2465668T3/es active Active
- 2007-03-29 US US11/731,774 patent/US7632926B2/en not_active Expired - Fee Related
- 2007-03-30 TW TW096111376A patent/TWI417300B/zh not_active IP Right Cessation
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2008
- 2008-09-18 MY MYPI20083653A patent/MY145042A/en unknown
- 2008-09-21 IL IL194221A patent/IL194221A/en not_active IP Right Cessation
- 2008-09-22 CR CR10308A patent/CR10308A/es not_active Application Discontinuation
- 2008-10-17 MA MA31306A patent/MA30382B1/fr unknown
- 2008-10-28 NO NO20084539A patent/NO20084539L/no not_active Application Discontinuation
- 2008-10-28 CO CO08115094A patent/CO6140067A2/es unknown
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2009
- 2009-09-29 US US12/569,463 patent/US8628778B2/en not_active Expired - Fee Related
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2014
- 2014-01-08 US US14/150,674 patent/US20140335076A1/en not_active Abandoned
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