CA2638913A1 - Phosphatase inhibitor protein-1 as a regulator of cardiac function - Google Patents
Phosphatase inhibitor protein-1 as a regulator of cardiac function Download PDFInfo
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- CA2638913A1 CA2638913A1 CA002638913A CA2638913A CA2638913A1 CA 2638913 A1 CA2638913 A1 CA 2638913A1 CA 002638913 A CA002638913 A CA 002638913A CA 2638913 A CA2638913 A CA 2638913A CA 2638913 A1 CA2638913 A1 CA 2638913A1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77232706P | 2006-02-10 | 2006-02-10 | |
| US60/772,327 | 2006-02-10 | ||
| PCT/US2007/003470 WO2007100465A2 (en) | 2006-02-10 | 2007-02-09 | Phosphatase inhibitor protein-1 as a regulator of cardiac function |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2638913A1 true CA2638913A1 (en) | 2007-09-07 |
Family
ID=38459499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002638913A Abandoned CA2638913A1 (en) | 2006-02-10 | 2007-02-09 | Phosphatase inhibitor protein-1 as a regulator of cardiac function |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7989606B2 (enExample) |
| EP (2) | EP1994043A4 (enExample) |
| JP (2) | JP2009525757A (enExample) |
| CN (1) | CN101437833A (enExample) |
| AU (1) | AU2007221470B2 (enExample) |
| CA (1) | CA2638913A1 (enExample) |
| WO (1) | WO2007100465A2 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2579519A1 (en) | 2004-09-09 | 2006-03-16 | The General Hospital Corporation | Modulating phosphatase activity in cardiac cells |
| WO2009090049A1 (en) * | 2008-01-14 | 2009-07-23 | European Molecular Biology Laboratory | Peptides for the specific binding and regulation of protein targets |
| EP2396343B1 (en) | 2009-02-11 | 2017-05-17 | The University of North Carolina At Chapel Hill | Modified virus vectors and methods of making and using the same |
| CN101942481B (zh) * | 2009-04-30 | 2012-07-25 | 中南大学 | 一种针对PKC γ基因RNA干扰的重组慢病毒载体的构建及其应用 |
| KR20130096731A (ko) | 2010-09-08 | 2013-08-30 | 할로자임, 아이엔씨 | 조건부 활성 치료적 단백질을 평가，확인 또는 진화시키는 방법 |
| CA2826273C (en) | 2011-02-10 | 2021-11-02 | The University Of North Carolina At Chapel Hill | Viral vectors with modified transduction profiles and methods of making and using the same |
| CA2866612C (en) | 2012-03-08 | 2018-01-16 | Halozyme, Inc. | Conditionally active ph-dependent cetuximab variant anti-epidermal growth factor receptor antibodies and method of use thereof |
| US10208085B2 (en) | 2012-07-05 | 2019-02-19 | Gwangju Institute Of Science And Technology | Decoy peptides inhibiting protein phosphatase 1-mediated dephosphorylation of phospholamban |
| ES2926774T3 (es) | 2013-03-15 | 2022-10-28 | Univ North Carolina Chapel Hill | Métodos y composiciones para vectores AAV de doble unión de glicano |
| AU2016206624B2 (en) | 2015-01-14 | 2020-08-06 | The University Of North Carolina At Chapel Hill | Methods and compositions for targeted gene transfer |
| WO2016134300A1 (en) | 2015-02-20 | 2016-08-25 | Board Of Regents, The University Of Texas System | Methods and compositions for attenuated chlamydia as vaccine and vector |
| IL314171A (en) | 2015-09-28 | 2024-09-01 | Univ Florida | Methods and compositions for antibody-evading virus vectors |
| WO2018170310A1 (en) | 2017-03-15 | 2018-09-20 | The University Of North Carolina At Chapel Hill | Polyploid adeno-associated virus vectors and methods of making and using the same |
| CA3092107A1 (en) | 2018-02-28 | 2019-09-06 | The University Of North Carolina At Chapel Hill | Methods and compositions for antibody-evading virus vectors |
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| AU2020263392A1 (en) | 2019-04-26 | 2021-10-28 | The University Of North Carolina At Chapel Hill | Methods and compositions for dual glycan binding AAV2.5 vector |
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| JP2024515626A (ja) | 2021-04-16 | 2024-04-10 | アスクレピオス バイオファーマシューティカル， インコーポレイテッド | 血液脳関門を横断し低減された液性応答を惹起する合理的ポリプロイドａａｖビリオン |
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| US5328470A (en) | 1989-03-31 | 1994-07-12 | The Regents Of The University Of Michigan | Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
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| US5858784A (en) | 1991-12-17 | 1999-01-12 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol- and liposome-based delivery |
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| WO1998017683A2 (en) * | 1996-10-23 | 1998-04-30 | Duke University | Human phosphatase inhibitor-1 gene and methods of screening for non-insulin dependent diabetes mellitus |
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| US20020159978A1 (en) | 2001-02-06 | 2002-10-31 | James Allen | Muscle-directed gene transfer by use of recombinant AAV-1 and AAV-6 virions |
| US20060275770A1 (en) * | 2002-11-27 | 2006-12-07 | Daniel Bednarik | Heart failure gene determination and therapeutic screening |
| JP2007505628A (ja) | 2003-09-19 | 2007-03-15 | チルドレンズ ホスピタル メディカル センター | 心収縮能及び心不全傾向の調節 |
| CA2579519A1 (en) * | 2004-09-09 | 2006-03-16 | The General Hospital Corporation | Modulating phosphatase activity in cardiac cells |
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| AU2007221470A1 (en) | 2007-09-07 |
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| WO2007100465A3 (en) | 2008-07-31 |
| US7989606B2 (en) | 2011-08-02 |
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