CA2622079A1 - Amide and carbamate derivatives of alkyl substituted n-[4-(4-amino-1h-imidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamides and methods - Google Patents

Amide and carbamate derivatives of alkyl substituted n-[4-(4-amino-1h-imidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamides and methods Download PDF

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Publication number
CA2622079A1
CA2622079A1 CA002622079A CA2622079A CA2622079A1 CA 2622079 A1 CA2622079 A1 CA 2622079A1 CA 002622079 A CA002622079 A CA 002622079A CA 2622079 A CA2622079 A CA 2622079A CA 2622079 A1 CA2622079 A1 CA 2622079A1
Authority
CA
Canada
Prior art keywords
compound
salt
quinolin
animal
imidazo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002622079A
Other languages
English (en)
French (fr)
Inventor
Tushar A. Kshirsagar
Shri Niwas
Bryon A. Merrill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Coley Pharmaceutical Group Inc
Original Assignee
Coley Pharmaceutical Group, Inc.
Tushar A. Kshirsagar
Shri Niwas
Bryon A. Merrill
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coley Pharmaceutical Group, Inc., Tushar A. Kshirsagar, Shri Niwas, Bryon A. Merrill filed Critical Coley Pharmaceutical Group, Inc.
Publication of CA2622079A1 publication Critical patent/CA2622079A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541—Non-condensed thiazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
CA002622079A 2005-09-09 2006-09-08 Amide and carbamate derivatives of alkyl substituted n-[4-(4-amino-1h-imidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamides and methods Abandoned CA2622079A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71594905P 2005-09-09 2005-09-09
US60/715,949 2005-09-09
PCT/US2006/035181 WO2007030777A2 (en) 2005-09-09 2006-09-08 Amide and carbamate derivatives of alkyl substituted n-[4-(4-amino-1h-imidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamides and methods

Publications (1)

Publication Number Publication Date
CA2622079A1 true CA2622079A1 (en) 2007-03-15

Family

ID=37836552

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002622079A Abandoned CA2622079A1 (en) 2005-09-09 2006-09-08 Amide and carbamate derivatives of alkyl substituted n-[4-(4-amino-1h-imidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamides and methods

Country Status (12)

Country Link
US (1) US8188111B2 (US08188111-20120529-C00016.png)
EP (1) EP1924582A4 (US08188111-20120529-C00016.png)
JP (1) JP2009507857A (US08188111-20120529-C00016.png)
KR (1) KR20080043877A (US08188111-20120529-C00016.png)
CN (1) CN101300257A (US08188111-20120529-C00016.png)
AU (1) AU2006287272A1 (US08188111-20120529-C00016.png)
BR (1) BRPI0615663A2 (US08188111-20120529-C00016.png)
CA (1) CA2622079A1 (US08188111-20120529-C00016.png)
EA (1) EA200800781A1 (US08188111-20120529-C00016.png)
IL (1) IL190032A0 (US08188111-20120529-C00016.png)
WO (1) WO2007030777A2 (US08188111-20120529-C00016.png)
ZA (1) ZA200803029B (US08188111-20120529-C00016.png)

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