CA2603987A1 - Micelle composition of polymer and passenger drug - Google Patents
Micelle composition of polymer and passenger drug Download PDFInfo
- Publication number
- CA2603987A1 CA2603987A1 CA002603987A CA2603987A CA2603987A1 CA 2603987 A1 CA2603987 A1 CA 2603987A1 CA 002603987 A CA002603987 A CA 002603987A CA 2603987 A CA2603987 A CA 2603987A CA 2603987 A1 CA2603987 A1 CA 2603987A1
- Authority
- CA
- Canada
- Prior art keywords
- peg
- micelle
- rapamycin
- tocopherol
- geldanamycin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A—HUMAN NECESSITIES
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- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US60/716,000 | 2005-09-09 | ||
| PCT/US2006/013800 WO2006110862A2 (en) | 2005-04-12 | 2006-04-12 | Micelle composition of polymer and passenger drug |
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| CA2603987A1 true CA2603987A1 (en) | 2006-10-19 |
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| AU2003230761A1 (en) * | 2002-03-29 | 2003-10-13 | Abbott Laboratories | Polymeric micelle formulations of hydrophobic compounds and methods |
| US20080082036A1 (en) * | 2006-04-25 | 2008-04-03 | Medtronic, Inc. | Cerebrospinal fluid shunt having long term anti-occlusion agent delivery |
| US20100119529A1 (en) * | 2006-05-12 | 2010-05-13 | Furgeson Darin Y | Elastin-like polymer delivery vehicles |
| DE102006038233A1 (de) * | 2006-08-07 | 2008-02-14 | Biotronik Vi Patent Ag | Markerkomposit für medizinische Implantate |
| US20080102127A1 (en) * | 2006-10-26 | 2008-05-01 | Gao Hai Y | Hybrid lipid-polymer nanoparticulate delivery composition |
| US20080248097A1 (en) * | 2007-02-26 | 2008-10-09 | Kwon Glen S | Polymeric micelles for combination drug delivery |
| WO2009006311A2 (en) * | 2007-06-29 | 2009-01-08 | Wisconsin Alumni Research Foundation | Structuring effect of cholesterol in peg-phospholipid micelles, drug delivery of amphotericin b, and combination antifungals |
| WO2009009067A2 (en) * | 2007-07-09 | 2009-01-15 | Kwon Glen S | Micelle encapsulation of theropeutic agents |
| US9422234B2 (en) * | 2007-11-30 | 2016-08-23 | The Johns Hopkins University | Prostate specific membrane antigen (PSMA) targeted nanoparticles for therapy of prostate cancer |
| US20090209757A1 (en) * | 2008-01-10 | 2009-08-20 | Santiago Ini | Processes for the preparation and purification of paliperidone palmitate |
| US20090232762A1 (en) * | 2008-03-11 | 2009-09-17 | May Pang Xiong | Compositions for delivery of therapeutic agents |
| US9271929B2 (en) * | 2008-11-25 | 2016-03-01 | École Polytechnique Fédérale De Lausanne (Epfl) | Block copolymers and uses thereof |
| EP2419136A4 (en) * | 2009-04-16 | 2013-01-02 | Merck Sharp & Dohme | COMPOSITIONS AND METHOD FOR THE TREATMENT OF CANCER |
| WO2010140869A2 (en) * | 2009-06-05 | 2010-12-09 | Iljin Copper Foil Co., Ltd. | Complex, multilayer using the same, and device coated with the multilayer |
| WO2011038278A2 (en) | 2009-09-25 | 2011-03-31 | Wisconsin Alumni Research Foundation | Micelle encapsulation of therapeutic agents |
| US9283211B1 (en) | 2009-11-11 | 2016-03-15 | Rapamycin Holdings, Llc | Oral rapamycin preparation and use for stomatitis |
| WO2015161139A1 (en) | 2014-04-16 | 2015-10-22 | Rapamycin Holdings, Llc | Oral rapamycin preparation and use for stomatitis |
| US10391059B2 (en) | 2009-11-11 | 2019-08-27 | Rapamycin Holdings, Inc. | Oral rapamycin nanoparticle preparations and use |
| AU2016202636B2 (en) * | 2009-12-30 | 2017-06-08 | Caliber Therapeutics, Llc | Balloon catheter systems for delivery of dry drug delivery vesicles to a vessel in the body |
| KR101267813B1 (ko) * | 2009-12-30 | 2013-06-04 | 주식회사 삼양바이오팜 | 향상된 수용해도를 갖는 라파마이신 함유 고분자나노입자 주사제형 조성물 및 그 제조방법, 및 방사선 요법과 병용하기 위한 항암 조성물 |
| ES2845398T3 (es) * | 2009-12-30 | 2021-07-26 | Caliber Therapeutics Llc | Sistemas de catéter de balón para administración de vesículas de administración de fármacos secos a un vaso en el cuerpo |
| EP2382966A1 (en) * | 2010-03-12 | 2011-11-02 | DSM IP Assets B.V. | Micelle compositions and process for the preparation thereof |
| CN107320734A (zh) | 2011-04-29 | 2017-11-07 | 西莱克塔生物科技公司 | 从合成纳米载体中控制释放免疫抑制剂 |
| WO2012151544A1 (en) | 2011-05-05 | 2012-11-08 | Wisconsin Alumni Research Foundation | Micelles for the solubilization of gossypol |
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| IL180785A (en) | 2004-07-19 | 2014-03-31 | Celator Pharmaceuticals Inc | Preparations containing particulate structures for the release of active substances |
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| US8173167B2 (en) | 2012-05-08 |
| JP2008535927A (ja) | 2008-09-04 |
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| US20060251710A1 (en) | 2006-11-09 |
| WO2006110862A2 (en) | 2006-10-19 |
| WO2006110862A3 (en) | 2007-07-05 |
| WO2006110862A9 (en) | 2008-08-07 |
| AU2006235538A1 (en) | 2006-10-19 |
| US20120309780A1 (en) | 2012-12-06 |
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