CA2595894C - Percutaneously absorbable preparation, percutaneously absorbable preparation holding sheet, and percutaneously absorbable preparation holding equipment - Google Patents

Percutaneously absorbable preparation, percutaneously absorbable preparation holding sheet, and percutaneously absorbable preparation holding equipment Download PDF

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Publication number
CA2595894C
CA2595894C CA2595894A CA2595894A CA2595894C CA 2595894 C CA2595894 C CA 2595894C CA 2595894 A CA2595894 A CA 2595894A CA 2595894 A CA2595894 A CA 2595894A CA 2595894 C CA2595894 C CA 2595894C
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CA
Canada
Prior art keywords
percutaneously absorbable
preparations
base
percutaneously
needle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2595894A
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English (en)
French (fr)
Other versions
CA2595894A1 (en
Inventor
Kanji Takada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioserentach Co Ltd
Original Assignee
Bioserentach Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36740525&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2595894(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bioserentach Co Ltd filed Critical Bioserentach Co Ltd
Publication of CA2595894A1 publication Critical patent/CA2595894A1/en
Application granted granted Critical
Publication of CA2595894C publication Critical patent/CA2595894C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/375Ascorbic acid, i.e. vitamin C; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727Heparin; Heparan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046Solid microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061Methods for using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2595894A 2005-01-31 2006-01-30 Percutaneously absorbable preparation, percutaneously absorbable preparation holding sheet, and percutaneously absorbable preparation holding equipment Expired - Fee Related CA2595894C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2005023276 2005-01-31
JP2005-023276 2005-01-31
JP2005-296691 2005-10-11
JP2005296691 2005-10-11
PCT/JP2006/301480 WO2006080508A1 (ja) 2005-01-31 2006-01-30 経皮吸収製剤、経皮吸収製剤保持シート、及び経皮吸収製剤保持用具

Publications (2)

Publication Number Publication Date
CA2595894A1 CA2595894A1 (en) 2006-08-03
CA2595894C true CA2595894C (en) 2013-09-10

Family

ID=36740525

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2595894A Expired - Fee Related CA2595894C (en) 2005-01-31 2006-01-30 Percutaneously absorbable preparation, percutaneously absorbable preparation holding sheet, and percutaneously absorbable preparation holding equipment

Country Status (7)

Country Link
US (2) US20080262444A1 (OSRAM)
EP (1) EP1844763B2 (OSRAM)
JP (2) JP4913030B2 (OSRAM)
KR (1) KR20070100820A (OSRAM)
AU (1) AU2006209421A1 (OSRAM)
CA (1) CA2595894C (OSRAM)
WO (1) WO2006080508A1 (OSRAM)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6445933A (en) * 1987-08-12 1989-02-20 Nissan Motor Control device in internal combustion engine with automatic gear
US20080262444A1 (en) 2005-01-31 2008-10-23 Bioserentach Co., Ltd. Percutaneously Absorbable Preparation, Percutaneously Absorbable Preparation Holding Sheet, and Percutaneously Absorbable Preparation Holding Equipment
EP2062611A4 (en) * 2006-08-18 2010-01-06 Toppan Printing Co Ltd MICRONADEL AND MICRONADEL
JP4954656B2 (ja) * 2006-09-28 2012-06-20 凸版印刷株式会社 針状体および針状体の製造方法
WO2008062832A1 (en) * 2006-11-22 2008-05-29 Toppan Printing Co., Ltd. Microneedle array and process for production thereof
EP2127693A1 (en) * 2007-01-29 2009-12-02 Medrx Co., Ltd. Process for producing microneedle of thermosensitive substance
US8546333B2 (en) 2007-02-01 2013-10-01 Technion Research & Development Foundation Limited Albumin fibers and fabrics and methods of generating and using same
JP2008284318A (ja) * 2007-05-15 2008-11-27 Kosumedei Seiyaku Kk 生体由来物質からなる投薬用微細針
KR20140143461A (ko) * 2007-08-06 2014-12-16 알레간 인코포레이티드 데스모프레신 약물 전달을 위한 방법 및 장치
US20100221314A1 (en) * 2007-10-18 2010-09-02 Hisamitsu Pharmaceutical Co., Inc. Microneedle Device
EP2213284B1 (en) * 2007-11-21 2017-11-15 BioSerenTach Co., Ltd. Preparation for application to body surface and preparation holding sheet for application to body surface
US20100298808A1 (en) * 2007-11-28 2010-11-25 Janisys Limited Method and a delivery device for administering an active substance to a subject
JP5267910B2 (ja) * 2008-02-28 2013-08-21 コスメディ製薬株式会社 マイクロニードルアレイ
US9028463B2 (en) 2008-06-30 2015-05-12 Hisamitsu Pharmaceutical Co., Inc. Microneedle device, and method for enhancing the efficacy of influenza vaccine by using microneedle device
JP5179976B2 (ja) * 2008-07-08 2013-04-10 富士フイルム株式会社 ニードルシートの製造方法
JP2010069270A (ja) * 2008-09-17 2010-04-02 Yoshiichi Tobinaga 機能剤投与デバイス、その製造方法及び製造装置
JP5063543B2 (ja) * 2008-09-22 2012-10-31 富士フイルム株式会社 経皮吸収シートの製造方法
JP5472673B2 (ja) * 2008-09-29 2014-04-16 コスメディ製薬株式会社 マイクロニードルアレイ
KR20100037389A (ko) * 2008-10-01 2010-04-09 연세대학교 산학협력단 다중 약물방출조절이 가능한 솔리드 마이크로구조체 및 이의 제조방법
US20110177297A1 (en) * 2008-10-02 2011-07-21 Nurim Wellness Co. Ltd. Method of manufacturing solid microstructure and solid microstructure manufactured based on same
DK2346563T3 (da) * 2008-10-07 2019-01-02 Tuo Jin Polymere faseovergangsmikronåle
WO2010109544A1 (ja) * 2009-03-27 2010-09-30 株式会社メドレックス 核酸を有効成分とする外用剤組成物
JP5514807B2 (ja) 2009-04-24 2014-06-04 株式会社 メドレックス 薬液担持用治具とそれを用いたマイクロニードルへの薬剤塗布方法
EP2429627B1 (en) * 2009-04-24 2017-06-14 Corium International, Inc. Methods for manufacturing microprojection arrays
JP2011012050A (ja) * 2009-06-03 2011-01-20 Bioserentack Co Ltd 多孔性基盤を用いたマイクロニードル・アレイとその製造方法
US8834423B2 (en) 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
KR101224939B1 (ko) * 2009-12-07 2013-01-22 가천대학교 산학협력단 활성 성분의 흡수 속도가 개선된 마이크로니들
WO2011094476A1 (en) * 2010-01-29 2011-08-04 Icon Medical Corp. Biodegradable protrusions on inflatable device
JPWO2011105496A1 (ja) * 2010-02-24 2013-06-20 久光製薬株式会社 マイクロニードルデバイス
AU2011228020A1 (en) * 2010-03-19 2012-09-27 Otsuka Pharmaceutical Co., Ltd. Proteoglycan-containing microneedle array
JP6327852B2 (ja) 2010-05-04 2018-05-23 コリウム インターナショナル, インコーポレイテッド 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス
JP5808102B2 (ja) * 2010-07-22 2015-11-10 コスメディ製薬株式会社 抗原を含有する経皮免疫製剤およびその製造方法
JP5672554B2 (ja) * 2010-08-19 2015-02-18 Jcrファーマ株式会社 皮下又は経皮吸収用組成物
EP4218891A1 (en) 2010-10-19 2023-08-02 Trustees Of Tufts College Silk fibroin-based microneedles and methods of making the same
WO2012105546A1 (ja) * 2011-01-31 2012-08-09 株式会社シクロケムバイオ 脂溶性物質を含む水溶液の製造方法
CA2795995C (en) * 2011-06-28 2020-03-24 Bioserentach Co. Ltd. Microneedle assembly formulation for skin treatment
JP2013162861A (ja) * 2012-02-10 2013-08-22 Bioserentack Co Ltd 細胞間液モニター用マイクロニードル
EP2821096B1 (en) 2012-02-29 2019-05-22 Toppan Printing Co., Ltd. Method for manufacturing needle-like material
HK1209658A1 (en) * 2012-05-01 2016-04-08 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Tip-loaded microneedle arrays for transdermal insertion
JP6213975B2 (ja) * 2012-09-13 2017-10-18 テイカ製薬株式会社 薬物含有超極細ファイバーおよびその利用
BR112015005073B1 (pt) 2012-09-13 2021-06-01 Amir Avraham Aplicador configurado para a administração de uma composição de melhoria de pele para uma pele e/ou subcútis de um sujeito, uso de um, microagulha e método para manufaturar uma microagulha
US12161831B2 (en) 2012-09-13 2024-12-10 Avraham Amir Microneedles and compositions for skin augmentation
AU2013364053B2 (en) 2012-12-21 2018-08-30 Corium Pharma Solutions, Inc. Microarray for delivery of therapeutic agent and methods of use
EP2946805A4 (en) * 2013-01-21 2016-10-26 Bukyoung Pharm Co Ltd MICRONADEL, FORM FOR THE PRODUCTION THEREOF AND METHOD OF MANUFACTURING THEREOF
US20140243763A1 (en) * 2013-02-25 2014-08-28 Sara Heikali Devices for the Placement of Medical Compounds in Natural Orifices of a Body
BR112015022625B1 (pt) 2013-03-15 2023-01-31 Corium, Inc Aparelho de microestrutura para entrega de agente terapêutico
ITMI20130586A1 (it) * 2013-04-11 2014-10-12 Azienda Ospedaliero Universitaria P Isana Microago e matrice di microaghi per uso medicale, e processo di produzione di detta matrice
GB201307262D0 (en) 2013-04-23 2013-05-29 Chowdhury Dewan F H Device for containment and release of drug formulation
JP5806701B2 (ja) 2013-05-07 2015-11-10 日本写真印刷株式会社 経皮投与用貼付剤の製造方法及び経皮投与用貼付剤
JP6428611B2 (ja) * 2013-06-06 2018-11-28 凸版印刷株式会社 針状体
EP3028735A4 (en) * 2013-07-30 2017-04-12 Asti Corporation Microneedle array and microneedle array manufacturing method
EP3068408A4 (en) * 2013-11-14 2017-09-06 University Medical Pharmaceuticals Corporation Microneedles for therapeutic agent delivery with improved mechanical properties
EP3117867B1 (en) 2014-03-12 2019-07-24 Labo Juversa Co., Ltd. Micro-needle preparation administration member for intradermal placement of target substance and apparatus for rapid administration of micro-needle preparation
JP5931110B2 (ja) * 2014-03-26 2016-06-08 日本写真印刷株式会社 錐体状突起シートの梱包体の製造方法
JP6565917B2 (ja) 2014-07-30 2019-08-28 凸版印刷株式会社 マイクロニードルユニット
MA41048A (fr) * 2014-10-07 2017-08-15 Qualyst Transp Solutions Llc Utilité d'une protéine dans la prédiction d'effets in vivo
JP6482323B2 (ja) 2015-03-03 2019-03-13 富士フイルム株式会社 経皮吸収シート
JP6317690B2 (ja) 2015-03-03 2018-04-25 富士フイルム株式会社 経皮吸収シート、及びその製造方法
US10441768B2 (en) 2015-03-18 2019-10-15 University of Pittsburgh—of the Commonwealth System of Higher Education Bioactive components conjugated to substrates of microneedle arrays
US10391289B2 (en) * 2015-04-13 2019-08-27 Lg Household & Health Care Ltd. Soluble microneedle containing ingredient for controlling release of neurotransmitters
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
WO2017002466A1 (ja) * 2015-06-30 2017-01-05 日本写真印刷株式会社 マイクロニードルシート及びその製造方法
JPWO2017018086A1 (ja) * 2015-07-29 2018-02-01 Nissha株式会社 マイクロニードルシート
WO2017066768A1 (en) 2015-10-16 2017-04-20 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Mullti-component biio-active drug delivery and controlled release to the skin by microneedle array devices
KR101785930B1 (ko) * 2015-12-30 2017-10-16 주식회사 쿼드메디슨 수분 환경에서 변형 및 변성 억제를 위한 마이크로 니들 및 그 제작 방법
US11744889B2 (en) 2016-01-05 2023-09-05 University of Pittsburgh—of the Commonwealth System of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
JP6970954B2 (ja) * 2016-03-16 2021-11-24 コスメディ製薬株式会社 フコイダン育毛剤
CN110917176B (zh) * 2018-08-31 2021-03-30 中科微针(北京)科技有限公司 一种可植入型缓释微针贴片及其制备方法
KR102175312B1 (ko) * 2018-10-08 2020-11-06 연세대학교 산학협력단 마이크로 구조체
TWI851964B (zh) * 2019-04-02 2024-08-11 寶齡富錦生技股份有限公司 微針裝置
JP2022532215A (ja) 2019-05-16 2022-07-13 ユニバーシティ オブ ピッツバーグ - オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 皮膚および非皮膚薬物送達のためのアンダーカット特徴を有するマイクロニードルアレイ
US20240198070A1 (en) * 2021-12-31 2024-06-20 Small'lab Co., Ltd. Microneedles comprising surface-modified microspheres and method of preparing the same
CN119451722A (zh) * 2022-06-30 2025-02-14 琳得科株式会社 微针结构体
KR102685131B1 (ko) * 2023-10-25 2024-07-15 주식회사 스몰랩 안정성이 증진된 리라글루타이드-함유 마이크로니들용 조성물 및 이의 이용

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4774091A (en) 1983-10-14 1988-09-27 Sumitomo Pharmaceuticals Company, Ltd. Long-term sustained-release preparation
US4754745A (en) * 1984-11-21 1988-07-05 Horowitz Bruce S Conformable sheet material for use in brachytherapy
US5582591A (en) * 1994-09-02 1996-12-10 Delab Delivery of solid drug compositions
US5837276A (en) 1994-09-02 1998-11-17 Delab Apparatus for the delivery of elongate solid drug compositions
US5542920A (en) 1994-09-12 1996-08-06 Delab Needle-less parenteral introduction device
JP3001381B2 (ja) 1994-09-16 2000-01-24 株式会社ディ・ディ・エス研究所 臓器移行性を有する多糖誘導体および薬物担体
JP3699141B2 (ja) 1994-09-24 2005-09-28 伸彦 由井 超分子構造の生体内分解性医薬高分子集合体及びその調製方法
JP3536186B2 (ja) 1995-02-27 2004-06-07 独立行政法人 科学技術振興機構 生体内分解性高分子ヒドロゲル
JP3538741B2 (ja) 1995-05-23 2004-06-14 独立行政法人 科学技術振興機構 複合刺激応答型生体内分解性高分子ヒドロゲル
TW487582B (en) 1995-08-11 2002-05-21 Nissan Chemical Ind Ltd Method for converting sparingly water-soluble medical substance to amorphous state
JP3832970B2 (ja) 1998-05-11 2006-10-11 独立行政法人科学技術振興機構 温度応答型生体内分解性高分子
AU767122B2 (en) * 1998-06-10 2003-10-30 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
US6503231B1 (en) 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
IL131074A0 (en) 1999-07-23 2001-03-19 Polygene Ltd A biodegradable polycation composition for delivery of an anionic macromolecule
AU2736501A (en) * 1999-12-30 2001-07-16 Redeon, Inc. Stacked microneedle systems
FR2809112B1 (fr) 2000-05-16 2004-05-07 Centre Nat Rech Scient Materiaux a base de polymeres biodegradables et son procede de preparation
GB0017999D0 (en) * 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
US6514193B2 (en) * 2000-11-16 2003-02-04 Microspherix Llc Method of administering a therapeutically active substance
EP1545705A4 (en) * 2000-11-16 2010-04-28 Microspherix Llc FLEXIBLE AND / OR ELASTIC BRACHYTHERAPY SEED OR STRAND
US6638246B1 (en) * 2000-11-28 2003-10-28 Scimed Life Systems, Inc. Medical device for delivery of a biologically active material to a lumen
EP1345646A2 (en) * 2000-12-14 2003-09-24 Georgia Tech Research Corporation Microneedle devices and production thereof
TWI259836B (en) 2001-04-12 2006-08-11 Astrazeneca Ab Modified release formulation suitable for antiarrhythmic compounds
CA2444391A1 (en) * 2001-04-13 2002-10-24 Becton Dickinson And Company Methods and devices for administration of substances into the intradermal layer of skin for systemic absorption
US6767341B2 (en) * 2001-06-13 2004-07-27 Abbott Laboratories Microneedles for minimally invasive drug delivery
EP1469903A2 (en) * 2001-09-28 2004-10-27 BioValve Technologies, Inc. Microneedle with membrane
JP4090018B2 (ja) * 2002-02-18 2008-05-28 For Head株式会社 機能性マイクロパイル及びその製造方法
ES2607128T3 (es) 2002-06-25 2017-03-29 Theraject, Inc. Microperforador de rápida disolución para administración de medicamentos y otras aplicaciones
JP2004081739A (ja) 2002-08-29 2004-03-18 Mitsuru Akashi ハイドロキシアパタイト−ポリマー複合材料の止血用組成物
US20040106904A1 (en) * 2002-10-07 2004-06-03 Gonnelli Robert R. Microneedle array patch
JP2004277325A (ja) * 2003-03-14 2004-10-07 Intorasu Ltd 皮膚吸収による物質のデリバリ方法、皮膚吸収による物質のデリバリに用いるピーリング剤、ピーリング装置、ならびにピーリング装置用ディスポーザブルパッド
JP2005023276A (ja) 2003-07-03 2005-01-27 Nippon Purai Kk ウインドモール用接着フィルム
KR20070001886A (ko) * 2003-10-28 2007-01-04 알자 코포레이션 치료용 펩타이드 및 단백질의 폴리머 컨쥬게이트의 피복된미세돌출부를 통한 전달
JP2005154321A (ja) * 2003-11-25 2005-06-16 Nano Device & System Research Inc アスコルビン酸投与用マイクロニードル
JP2005152180A (ja) * 2003-11-25 2005-06-16 Nano Device & System Research Inc インスリン投与用マイクロニードル
US7361182B2 (en) 2003-12-19 2008-04-22 Lightnix, Inc. Medical lancet
JP4210231B2 (ja) 2004-03-25 2009-01-14 株式会社資生堂 皮膚のシワを改善する美容方法及びシワ改善具
US7591806B2 (en) * 2004-05-18 2009-09-22 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
US20080262444A1 (en) 2005-01-31 2008-10-23 Bioserentach Co., Ltd. Percutaneously Absorbable Preparation, Percutaneously Absorbable Preparation Holding Sheet, and Percutaneously Absorbable Preparation Holding Equipment
JP2005296691A (ja) 2005-07-13 2005-10-27 Aruze Corp 遊技機
US20090099502A1 (en) * 2006-04-07 2009-04-16 Hisamitsu Pharmaceutical Co., Inc. Microneedle Device And Transdermal Administration Device Provided With Microneedles

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JP2009138010A (ja) 2009-06-25
US8506980B2 (en) 2013-08-13
EP1844763A1 (en) 2007-10-17
EP1844763A4 (en) 2010-08-18
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JPWO2006080508A1 (ja) 2008-06-19
CA2595894A1 (en) 2006-08-03
EP1844763B2 (en) 2022-09-07
JP4913030B2 (ja) 2012-04-11
JP4800399B2 (ja) 2011-10-26
KR20070100820A (ko) 2007-10-11
US20080262444A1 (en) 2008-10-23
US20110046575A1 (en) 2011-02-24

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