CA2583710A1 - Aryl sulfonamide peri-substituted bicyclics for occlusive artery disease - Google Patents
Aryl sulfonamide peri-substituted bicyclics for occlusive artery disease Download PDFInfo
- Publication number
- CA2583710A1 CA2583710A1 CA002583710A CA2583710A CA2583710A1 CA 2583710 A1 CA2583710 A1 CA 2583710A1 CA 002583710 A CA002583710 A CA 002583710A CA 2583710 A CA2583710 A CA 2583710A CA 2583710 A1 CA2583710 A1 CA 2583710A1
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- Prior art keywords
- substituted
- mmol
- compound according
- chosen
- loweralkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
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- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
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| Application Number | Priority Date | Filing Date | Title |
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| US61820204P | 2004-10-12 | 2004-10-12 | |
| US60/618,202 | 2004-10-12 | ||
| PCT/US2005/036558 WO2006044405A1 (en) | 2004-10-12 | 2005-10-11 | Aryl sulfonamide peri-substituted bicyclics for occlusive artery disease |
Publications (1)
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| CA2583710A1 true CA2583710A1 (en) | 2006-04-27 |
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| CA002583710A Abandoned CA2583710A1 (en) | 2004-10-12 | 2005-10-11 | Aryl sulfonamide peri-substituted bicyclics for occlusive artery disease |
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| AP2007004244A0 (en) | 2005-05-10 | 2007-12-31 | Intermune Inc | Method of modulating stress-activated protein kinase system |
| US20090163586A1 (en) | 2007-12-20 | 2009-06-25 | Astrazeneca Ab | Bis-(Sulfonylamino) Derivatives in Therapy 205 |
| EP2296653B1 (en) | 2008-06-03 | 2016-01-27 | Intermune, Inc. | Compounds and methods for treating inflammatory and fibrotic disorders |
| FR2938538B1 (fr) * | 2008-11-17 | 2011-08-05 | Univ Nice Sophia Antipolis | Procede de preparation d'acides et d'esters boroniques en presence de magnesium metallique |
| AU2010232729A1 (en) | 2009-03-31 | 2011-10-20 | Arqule, Inc. | Substituted indolo-pyridinone compounds |
| JP5841361B2 (ja) * | 2011-06-29 | 2016-01-13 | 壽製薬株式会社 | 三環性化合物及びそれを含有する医薬組成物 |
| JO3407B1 (ar) | 2012-05-31 | 2019-10-20 | Eisai R&D Man Co Ltd | مركبات رباعي هيدرو بيرازولو بيريميدين |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| CA2924843A1 (en) * | 2013-09-27 | 2015-04-02 | Allergan, Inc. | Compounds and methods for skin repair |
| RU2692485C2 (ru) | 2014-04-02 | 2019-06-25 | Интермьюн, Инк. | Противофиброзные пиридиноны |
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| GB201810581D0 (en) | 2018-06-28 | 2018-08-15 | Ctxt Pty Ltd | Compounds |
| SI4299135T1 (sl) | 2019-06-18 | 2025-12-31 | Pfizer Inc. | Benzizoksazolni sulfonamidni derivati |
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| JP4249804B2 (ja) * | 1995-04-03 | 2009-04-08 | ノバルティス・アクチエンゲゼルシャフト | ピラゾール誘導体およびその製造法 |
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| BR0015995A (pt) * | 1999-11-30 | 2002-08-06 | Pfizer Prod Inc | Compostos 2,4-diaminopirimidina úteis como imunossupressores |
| MXPA04001253A (es) * | 2001-08-09 | 2004-06-03 | Ono Pharmaceutical Co | Derivados de acidos carboxilicos y agente farmaceutico que comprende los mismos como ingrediente activo. |
| WO2004078719A1 (ja) * | 2003-03-06 | 2004-09-16 | Ono Pharmaceutical Co., Ltd. | インドール誘導体化合物およびその化合物を有効成分とする薬剤 |
| JP2007516203A (ja) * | 2003-07-09 | 2007-06-21 | バイオリポックス エービー | 炎症の治療に有用なインドール類 |
| JP5138938B2 (ja) * | 2003-12-19 | 2013-02-06 | プレキシコン インコーポレーテッド | Ｒｅｔ調節剤の開発のための化合物および方法 |
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2008
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Also Published As
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| KR20070085340A (ko) | 2007-08-27 |
| NO20072269L (no) | 2007-07-06 |
| WO2006044405A1 (en) | 2006-04-27 |
| RU2407736C2 (ru) | 2010-12-27 |
| RU2007115520A (ru) | 2008-10-27 |
| EP1812426A1 (en) | 2007-08-01 |
| IL182489A0 (en) | 2007-09-20 |
| SG156637A1 (en) | 2009-11-26 |
| HK1110580A1 (en) | 2008-07-18 |
| BRPI0517417A (pt) | 2008-10-07 |
| JP2008515980A (ja) | 2008-05-15 |
| CN101076529A (zh) | 2007-11-21 |
| ATE512144T1 (de) | 2011-06-15 |
| AU2005295902A1 (en) | 2006-04-27 |
| NZ554493A (en) | 2009-09-25 |
| US20090075985A1 (en) | 2009-03-19 |
| MX2007004526A (es) | 2007-09-21 |
| US20060142348A1 (en) | 2006-06-29 |
| EP1812426B1 (en) | 2011-06-08 |
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| FZDE | Discontinued |