CA2583244A1 - Treatment of graft-versus-host disease and leukemia with beclomethasone dipropionate and prednisone - Google Patents

Treatment of graft-versus-host disease and leukemia with beclomethasone dipropionate and prednisone Download PDF

Info

Publication number
CA2583244A1
CA2583244A1 CA002583244A CA2583244A CA2583244A1 CA 2583244 A1 CA2583244 A1 CA 2583244A1 CA 002583244 A CA002583244 A CA 002583244A CA 2583244 A CA2583244 A CA 2583244A CA 2583244 A1 CA2583244 A1 CA 2583244A1
Authority
CA
Canada
Prior art keywords
bdp
day
days
treatment
administered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002583244A
Other languages
English (en)
French (fr)
Inventor
George B. Mcdonald
Nicholas Stergis
Steve Kanzer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Soligenix Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2583244A1 publication Critical patent/CA2583244A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Surgery (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002583244A 2004-12-30 2005-12-30 Treatment of graft-versus-host disease and leukemia with beclomethasone dipropionate and prednisone Abandoned CA2583244A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64017804P 2004-12-30 2004-12-30
US60/640,178 2004-12-30
PCT/US2005/047666 WO2006072093A2 (en) 2004-12-30 2005-12-30 Treatment of graft-versus-host disease and leukemia with beclomethasone dipropionate and prednisone

Publications (1)

Publication Number Publication Date
CA2583244A1 true CA2583244A1 (en) 2006-07-06

Family

ID=36615583

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002583244A Abandoned CA2583244A1 (en) 2004-12-30 2005-12-30 Treatment of graft-versus-host disease and leukemia with beclomethasone dipropionate and prednisone

Country Status (13)

Country Link
US (1) US20060252735A1 (de)
EP (1) EP1830857B1 (de)
JP (1) JP2008526773A (de)
KR (1) KR20070089701A (de)
CN (2) CN102218070A (de)
AT (1) ATE481102T1 (de)
AU (1) AU2005321826B2 (de)
CA (1) CA2583244A1 (de)
DE (1) DE602005023655D1 (de)
DK (1) DK1830857T3 (de)
IL (1) IL182462A0 (de)
NZ (1) NZ554326A (de)
WO (1) WO2006072093A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090143328A1 (en) * 2001-08-13 2009-06-04 Mcdonald George Method of Treating Cancer by Administration of Topical Active Corticosteroids
EP2373160B1 (de) * 2008-12-08 2017-10-25 Soligenix, Inc. Topisch aktive steroide zur verwendung bei strahlenschäden
ES2909662T3 (es) * 2014-08-07 2022-05-09 Laevoroc Immunology Ag Composiciones que comprenden un inhibidor de PNP para uso en el tratamiento de la recaída de malignidad después de un trasplante de células madre hematopoyéticas
CN106236736A (zh) * 2016-09-26 2016-12-21 安徽省逸欣铭医药科技有限公司 二丙酸倍氯米松肠溶缓释片及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096728A (en) * 1996-02-09 2000-08-01 Amgen Inc. Composition and method for treating inflammatory diseases
US5747474A (en) * 1996-07-29 1998-05-05 Immune Modulation, Inc. Immunosuppression by administration of N6,N6 -disubstituted cAMP's, analogues thereof, and related nucleosides
US6096731A (en) * 1998-06-24 2000-08-01 Institute For Drug Research, Inc. Method for preventing tissue damage associated with graft-versus-host or host-versus-graft disease following transplantation
US20020086857A1 (en) * 2000-09-15 2002-07-04 Mcdonald George B. Method of long-term treatment of graft-versus-host disease using topical active corticosterioids
CA2441007C (en) * 2001-03-15 2009-06-09 Enteron Pharmaceuticals, Inc. Method of treating inflammatory disorders of the gastrointestinal tract using topical active corticosteroids
US20030032631A1 (en) 2001-08-13 2003-02-13 Mcdonald George B. Method of treatment of cancer by controlling graft-versus-leukemia using topical active corticosteriods
JP4014912B2 (ja) * 2001-09-28 2007-11-28 株式会社ルネサステクノロジ 半導体装置

Also Published As

Publication number Publication date
CN101060848A (zh) 2007-10-24
DE602005023655D1 (de) 2010-10-28
US20060252735A1 (en) 2006-11-09
JP2008526773A (ja) 2008-07-24
EP1830857B1 (de) 2010-09-15
DK1830857T3 (da) 2011-02-07
IL182462A0 (en) 2008-04-13
CN101060848B (zh) 2011-06-22
WO2006072093A3 (en) 2007-03-22
AU2005321826A1 (en) 2006-07-06
CN102218070A (zh) 2011-10-19
AU2005321826B2 (en) 2012-03-15
ATE481102T1 (de) 2010-10-15
NZ554326A (en) 2010-10-29
EP1830857A2 (de) 2007-09-12
WO2006072093A2 (en) 2006-07-06
EP1830857A4 (de) 2008-02-27
KR20070089701A (ko) 2007-08-31

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20131231