CA2564066A1 - Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation - Google Patents
Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation Download PDFInfo
- Publication number
- CA2564066A1 CA2564066A1 CA002564066A CA2564066A CA2564066A1 CA 2564066 A1 CA2564066 A1 CA 2564066A1 CA 002564066 A CA002564066 A CA 002564066A CA 2564066 A CA2564066 A CA 2564066A CA 2564066 A1 CA2564066 A1 CA 2564066A1
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- Prior art keywords
- derivative
- carotenoid
- analog
- subject
- formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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- A—HUMAN NECESSITIES
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- A61K31/66—Phosphorus compounds
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
- A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
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- A—HUMAN NECESSITIES
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- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
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- Public Health (AREA)
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- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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US20050009788A1 (en) * | 2002-07-29 | 2005-01-13 | Lockwood Samuel Fournier | Carotenoid ester analogs or derivatives for controlling connexin 43 expression |
US7375133B2 (en) * | 2002-07-29 | 2008-05-20 | Cardax Pharmaceuticals, Inc. | Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease |
US7345091B2 (en) * | 2002-07-29 | 2008-03-18 | Cardax Pharmaceuticals, Inc. | Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease |
US20050059659A1 (en) * | 2002-07-29 | 2005-03-17 | Lockwood Samuel Fournier | Carotenoid analogs or derivatives for controlling C-reactive protein levels |
US20050049248A1 (en) * | 2002-07-29 | 2005-03-03 | Lockwood Samuel Fournier | Carotenoid ether analogs or derivatives for controlling C-reactive protein levels |
US20050059635A1 (en) * | 2002-07-29 | 2005-03-17 | Lockwood Samuel Fournier | Carotenoid ester analogs or derivatives for controlling C-reactive protein levels |
US7763649B2 (en) * | 2002-07-29 | 2010-07-27 | Cardax Pharmaceuticals, Inc. | Carotenoid analogs or derivatives for controlling connexin 43 expression |
CA2495167C (en) * | 2002-07-29 | 2018-08-21 | Hawaii Biotech, Inc. | Structural carotenoid analogs for the inhibition and amelioration of disease |
US7723327B2 (en) * | 2002-07-29 | 2010-05-25 | Cardax Pharmaceuticals, Inc. | Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease |
US7320997B2 (en) * | 2002-07-29 | 2008-01-22 | Cardax Pharmaceuticals, Inc. | Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease |
US20050026874A1 (en) * | 2002-07-29 | 2005-02-03 | Lockwood Samuel Fournier | Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease |
US20050004235A1 (en) * | 2002-07-29 | 2005-01-06 | Lockwood Samuel Fournier | Carotenoid analogs or derivatives for the inhibition and amelioration of liver disease |
US20060058269A1 (en) * | 2004-04-14 | 2006-03-16 | Lockwood Samuel F | Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation |
US7247752B2 (en) * | 2004-10-01 | 2007-07-24 | Cardax Pharmaceuticals, Inc. | Methods for the synthesis of astaxanthin |
CA2611137A1 (en) * | 2005-03-23 | 2006-09-28 | Cardax Pharmaceuticals, Inc. | Water-dispersible carotenoids, including analogs and derivatives |
WO2006105214A2 (en) * | 2005-03-29 | 2006-10-05 | Cardax Pharmaceuticals, Inc. | Reduction in complement activation and inflammation during tissue injury by carotenoids, carotenoid analogs, or derivatives thereof |
WO2006119125A2 (en) * | 2005-04-29 | 2006-11-09 | Cardax Pharmaceuticals, Inc. | Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates |
EP1957057A1 (en) * | 2005-12-07 | 2008-08-20 | Cardax Pharmaceuticals, Inc. | Structural carotenoid analogs or derivatives for the modulation of systemic and/or target organ redox status |
JP2007254411A (ja) * | 2006-03-24 | 2007-10-04 | Tokyo Univ Of Pharmacy & Life Science | アグリカナーゼ産生阻害剤 |
US20070293568A1 (en) * | 2006-06-16 | 2007-12-20 | Yamaha Hatsudoki Kabushiki Kaisha | Neurocyte Protective Agent |
US20090118227A1 (en) | 2007-11-07 | 2009-05-07 | Bristol-Myers Squibb Company | Carotenoid-containing compositions and methods |
AU2009319860B2 (en) | 2008-11-26 | 2016-07-21 | Board Of Regents, The University Of Texas System | A new family of pain producing substances and methods to produce novel analgesic drugs |
US11055332B1 (en) | 2010-10-08 | 2021-07-06 | Google Llc | Adaptive sorting of results |
US9029342B2 (en) | 2012-09-17 | 2015-05-12 | Board Of Regents Of The University Of Texas System | Compositions of matter that reduce pain, shock, and inflammation by blocking linoleic acid metabolites and uses thereof |
TWI654171B (zh) * | 2014-05-20 | 2019-03-21 | 日商艾斯塔製藥股份有限公司 | 類胡蘿蔔素衍生物、其藥理學上可容許之鹽或者其藥理學上可容許之酯類或醯胺類 |
US20160367620A1 (en) | 2015-06-19 | 2016-12-22 | Harry B. Demopoulos | Glutathione |
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US3989757A (en) | 1973-08-29 | 1976-11-02 | Hoffmann-La Roche Inc. | Isomerizing cis-carotenoids to all-trans-carotenoids |
US3965261A (en) | 1975-04-29 | 1976-06-22 | University Of Virginia | Method for treating papillomas |
US3975519A (en) | 1975-06-09 | 1976-08-17 | University Of Virginia | Method for increasing the oxygen partial pressure in the bloodstream of mammals |
US4070460A (en) | 1975-11-10 | 1978-01-24 | University Of Virginia Patents Foundation | Method for treating cerebral edema |
US4009270A (en) | 1975-11-21 | 1977-02-22 | The University Of Virginia | Method for treating spinal cord injury |
US4038144A (en) | 1976-04-19 | 1977-07-26 | The University Of Virginia | Method of increasing fermentation yields |
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-
2005
- 2005-04-14 WO PCT/US2005/012811 patent/WO2005102356A1/en active Application Filing
- 2005-04-14 US US11/106,378 patent/US7691901B2/en not_active Expired - Fee Related
- 2005-04-14 CA CA002564066A patent/CA2564066A1/en not_active Abandoned
- 2005-04-14 EP EP05735338A patent/EP1750723A1/en not_active Ceased
Also Published As
Publication number | Publication date |
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US20050261254A1 (en) | 2005-11-24 |
EP1750723A1 (en) | 2007-02-14 |
WO2005102356A1 (en) | 2005-11-03 |
US7691901B2 (en) | 2010-04-06 |
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