CA2544373A1 - Blood test prototypes and methods for the detection of circulating tumor and endothelial cells - Google Patents

Blood test prototypes and methods for the detection of circulating tumor and endothelial cells Download PDF

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Publication number
CA2544373A1
CA2544373A1 CA002544373A CA2544373A CA2544373A1 CA 2544373 A1 CA2544373 A1 CA 2544373A1 CA 002544373 A CA002544373 A CA 002544373A CA 2544373 A CA2544373 A CA 2544373A CA 2544373 A1 CA2544373 A1 CA 2544373A1
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CA
Canada
Prior art keywords
cells
cell
blood
cell adhesion
cam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002544373A
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English (en)
French (fr)
Inventor
Wen-Tien Chen
Lee Chen
Che Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vitatex Inc
Original Assignee
Vitatex, Inc.
Wen-Tien Chen
Lee Chen
Che Chen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vitatex, Inc., Wen-Tien Chen, Lee Chen, Che Chen filed Critical Vitatex, Inc.
Publication of CA2544373A1 publication Critical patent/CA2544373A1/en
Abandoned legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • B01L3/50825—Closing or opening means, corks, bungs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04—Cell isolation or sorting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0093—Purging against cancer cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/75—Fibrin; Fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physiology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sustainable Development (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002544373A 2003-10-31 2004-10-30 Blood test prototypes and methods for the detection of circulating tumor and endothelial cells Abandoned CA2544373A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US51657103P 2003-10-31 2003-10-31
US60/516,571 2003-10-31
PCT/US2004/036177 WO2005043121A2 (en) 2003-10-31 2004-10-30 Blood test prototypes and methods for the detection of circulating tumor and endothelial cells

Publications (1)

Publication Number Publication Date
CA2544373A1 true CA2544373A1 (en) 2005-05-12

Family

ID=34549552

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002544373A Abandoned CA2544373A1 (en) 2003-10-31 2004-10-30 Blood test prototypes and methods for the detection of circulating tumor and endothelial cells

Country Status (7)

Country Link
EP (1) EP1706720A4 (zh)
JP (1) JP2007526761A (zh)
CN (2) CN1922304A (zh)
AU (1) AU2004286307A1 (zh)
CA (1) CA2544373A1 (zh)
HK (1) HK1209778A1 (zh)
WO (1) WO2005043121A2 (zh)

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US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
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CN106796237B (zh) * 2014-07-22 2018-12-04 株式会社癌症免疫研究所 末梢循环癌细胞的检测装置
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JP6901253B2 (ja) * 2015-10-21 2021-07-14 株式会社日本触媒 接着性細胞培養用基材、ならびにこれを利用した細胞培養容器および細胞培養方法
CN105420088B (zh) * 2015-11-11 2017-12-29 深圳市达科为生物工程有限公司 一种细胞分离管
KR20170070839A (ko) * 2015-12-14 2017-06-22 주식회사 퀀타매트릭스 이종 세포들의 혼합물로부터 특정 세포를 구별하는 방법
JP6518985B2 (ja) * 2016-09-29 2019-05-29 住友ゴム工業株式会社 がん細胞捕捉方法
JP7118059B2 (ja) * 2016-11-02 2022-08-15 イー・エム・デイー・ミリポア・コーポレイシヨン 細胞培養液からマイクロキャリアを分離するための容器
CN110366597B (zh) * 2016-12-20 2024-03-29 善威生物私人有限公司 用蛋白酶抑制剂进行血液图谱分析
CN108220233B (zh) * 2016-12-21 2021-07-09 上海透景诊断科技有限公司 细胞分离器具表面处理方法、相关器具、外周血稀有细胞或循环肿瘤细胞快速高效分离方法
EP3342485B1 (de) * 2017-01-02 2020-07-08 Thinxxs Microtechnology Ag Halterung für reagenzträgerelemente
CN106754650B (zh) * 2017-02-24 2018-10-02 哈尔滨中科赛恩斯生物技术有限公司 一种骨髓来源的内皮祖细胞培养方法
CN106840816A (zh) * 2017-03-14 2017-06-13 骏实生物科技(上海)有限公司 一种全自动循环肿瘤细胞阴性富集装置
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CN108031614B (zh) * 2017-12-14 2020-04-17 四川福德机器人股份有限公司 一种燃气表的涂胶自动补偿方法及采用该方法的装置
WO2019185874A1 (en) * 2018-03-30 2019-10-03 Exosomics S.p.A. Use of hollow fibers to obtain blood or a blood derivative impoverished from blood cells and platelets derived extracellular vesicles
CN109294973A (zh) * 2018-10-18 2019-02-01 重庆医科大学 一种基于磁珠法阴性去除血尿白细胞富集上皮细胞的方法
CN109887542A (zh) * 2019-02-12 2019-06-14 嘉兴海云惠智医疗科技有限公司 一种基于云计算的肿瘤个体化基因检测智能解读系统
CN111751543A (zh) * 2019-03-27 2020-10-09 南方医科大学南方医院 一种稀有肿瘤细胞富集方法及试剂盒
JP6886667B2 (ja) * 2019-03-27 2021-06-16 住友ゴム工業株式会社 がん細胞捕捉方法
CN111235021B (zh) * 2020-03-06 2022-09-27 大连海事大学 一种双液相外周血中循环肿瘤细胞分离与检测装置及方法
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Also Published As

Publication number Publication date
HK1209778A1 (zh) 2016-04-08
CN104531529A (zh) 2015-04-22
WO2005043121A2 (en) 2005-05-12
WO2005043121A3 (en) 2006-08-24
EP1706720A2 (en) 2006-10-04
CN1922304A (zh) 2007-02-28
AU2004286307A1 (en) 2005-05-12
EP1706720A4 (en) 2007-02-28
JP2007526761A (ja) 2007-09-20

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