CA2532078A1 - Derives de naphtylene constituant des inhibiteurs du cytochrome p450 - Google Patents
Derives de naphtylene constituant des inhibiteurs du cytochrome p450 Download PDFInfo
- Publication number
- CA2532078A1 CA2532078A1 CA002532078A CA2532078A CA2532078A1 CA 2532078 A1 CA2532078 A1 CA 2532078A1 CA 002532078 A CA002532078 A CA 002532078A CA 2532078 A CA2532078 A CA 2532078A CA 2532078 A1 CA2532078 A1 CA 2532078A1
- Authority
- CA
- Canada
- Prior art keywords
- 10alkyl
- 10alkynyl
- 10alkenyl
- cycloc3
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4192—1,2,3-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48638203P | 2003-07-10 | 2003-07-10 | |
US60/486,382 | 2003-07-10 | ||
PCT/US2004/022282 WO2005007631A1 (fr) | 2003-07-10 | 2004-07-12 | Derives de naphtylene constituant des inhibiteurs du cytochrome p450 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2532078A1 true CA2532078A1 (fr) | 2005-01-27 |
Family
ID=34079229
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002532078A Abandoned CA2532078A1 (fr) | 2003-07-10 | 2004-07-12 | Derives de naphtylene constituant des inhibiteurs du cytochrome p450 |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1654236A1 (fr) |
JP (1) | JP4832295B2 (fr) |
KR (1) | KR20060052799A (fr) |
CN (1) | CN1819996B (fr) |
AU (1) | AU2004257257B2 (fr) |
BR (1) | BRPI0412424A (fr) |
CA (1) | CA2532078A1 (fr) |
IL (1) | IL172812A0 (fr) |
IS (1) | IS8223A (fr) |
MX (1) | MXPA06000401A (fr) |
NO (1) | NO20060114L (fr) |
RU (1) | RU2363696C2 (fr) |
SG (1) | SG144941A1 (fr) |
UA (1) | UA87822C2 (fr) |
WO (1) | WO2005007631A1 (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1696899A1 (fr) * | 2003-12-17 | 2006-09-06 | Allergan, Inc. | Procedes permettant de traiter des troubles sensibles au retinoide au moyen d'inhibiteurs selectifs de cyp26a et de cyp26b |
US7662844B2 (en) | 2004-07-12 | 2010-02-16 | Osi Pharmaceuticals, Inc. | Naphthylene derivatives as cytochrome P450 inhibitors |
US8513291B2 (en) | 2010-06-01 | 2013-08-20 | Angion Biomedica Corp. | Cytochrome P450 inhibitors and uses thereof |
US10414760B2 (en) | 2016-11-29 | 2019-09-17 | Angion Biomedica Corp. | Cytochrome P450 inhibitors and uses thereof |
KR20180039185A (ko) * | 2010-11-13 | 2018-04-17 | 이노크린 파마슈티컬즈, 인크. | 금속효소 억제제 화합물 |
EP2651905B1 (fr) * | 2010-12-13 | 2017-07-19 | Innocrin Pharmaceuticals, Inc. | Composés inhibiteurs de métalloenzyme |
CN102586187A (zh) * | 2012-02-23 | 2012-07-18 | 深圳市中美康士生物科技有限公司 | 一种中性粒细胞体外保存方法及培养基 |
WO2014015137A2 (fr) * | 2012-07-18 | 2014-01-23 | Angion Biomedica Corp. | Compositions et méthodes de traitement de maladies dysprolifératives |
AU2015301891B2 (en) | 2014-08-11 | 2019-12-05 | Angion Biomedica Corporation | Cytochrome P450 inhibitors and uses thereof |
CN104523967B (zh) * | 2014-12-12 | 2017-08-01 | 扬子江药业集团北京海燕药业有限公司 | 一种柏艾胶囊作为cyp酶抑制剂的应用 |
AU2015374231B2 (en) | 2014-12-31 | 2020-07-23 | Angion Biomedica Corp. | Methods and agents for treating disease |
GB201602572D0 (en) * | 2016-02-12 | 2016-03-30 | Eriksson Leif And Strid Ake And Sirsjö Allan | New compound and uses |
WO2018065288A1 (fr) | 2016-10-07 | 2018-04-12 | Bayer Cropscience Aktiengesellschaft | Dérivés de 2-[2-phényl-1-(sulfonylméthyl)vinyl]-imidazo[4,5-b]pyridine et composés apparentés utilisés comme pesticides en protection des plantes |
EP3568395A1 (fr) | 2017-01-10 | 2019-11-20 | Bayer Aktiengesellschaft | Dérivés hétérocycliques utilisés comme pesticides |
TW201837036A (zh) | 2017-01-10 | 2018-10-16 | 德商拜耳廠股份有限公司 | 作為除害劑之雜環衍生物(一) |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL291944A (fr) * | 1960-05-04 | |||
NL131915C (fr) * | 1966-07-27 | |||
DE3508903A1 (de) * | 1985-03-13 | 1986-09-18 | Hoechst Ag, 6230 Frankfurt | Neue 3-pyridylmethylnaphtylderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
DE3628545A1 (de) * | 1985-09-23 | 1987-04-23 | Hoechst Ag | Arylmethylazole und deren salze, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung |
AU5285593A (en) * | 1992-10-21 | 1994-05-09 | Sankyo Company Limited | Azole compound |
JP4546589B2 (ja) * | 1998-04-23 | 2010-09-15 | 武田薬品工業株式会社 | ナフタレン誘導体 |
ATE293102T1 (de) * | 1998-04-23 | 2005-04-15 | Takeda Pharmaceutical | Naphthalene derivate ,ihre herstellung und verwendung |
FR2796070B1 (fr) * | 1999-07-06 | 2003-02-21 | Lipha | Derives de benzodiazepines utilisables dans le traitement de dyslipidemies, de l'atherosclerose et du diabete, compositions pharmaceutiques les contenant et procedes de preparation |
PE20010781A1 (es) * | 1999-10-22 | 2001-08-08 | Takeda Chemical Industries Ltd | Compuestos 1-(1h-imidazol-4-il)-1-(naftil-2-sustituido)etanol, su produccion y utilizacion |
JP4520012B2 (ja) * | 1999-10-22 | 2010-08-04 | 武田薬品工業株式会社 | 1−置換−1−(1h−イミダゾール−4−イル)メタノール類 |
-
2004
- 2004-07-12 SG SG200805435-5A patent/SG144941A1/en unknown
- 2004-07-12 JP JP2006518965A patent/JP4832295B2/ja not_active Expired - Fee Related
- 2004-07-12 WO PCT/US2004/022282 patent/WO2005007631A1/fr active Application Filing
- 2004-07-12 KR KR1020067000669A patent/KR20060052799A/ko not_active Application Discontinuation
- 2004-07-12 BR BRPI0412424-3A patent/BRPI0412424A/pt not_active IP Right Cessation
- 2004-07-12 MX MXPA06000401A patent/MXPA06000401A/es active IP Right Grant
- 2004-07-12 AU AU2004257257A patent/AU2004257257B2/en not_active Expired - Fee Related
- 2004-07-12 CA CA002532078A patent/CA2532078A1/fr not_active Abandoned
- 2004-07-12 EP EP04756894A patent/EP1654236A1/fr not_active Withdrawn
- 2004-07-12 RU RU2006103996/04A patent/RU2363696C2/ru not_active IP Right Cessation
- 2004-07-12 CN CN200480019732XA patent/CN1819996B/zh not_active Expired - Fee Related
- 2004-12-07 UA UAA200601312A patent/UA87822C2/ru unknown
-
2005
- 2005-12-26 IL IL172812A patent/IL172812A0/en unknown
-
2006
- 2006-01-06 NO NO20060114A patent/NO20060114L/no not_active Application Discontinuation
- 2006-01-10 IS IS8223A patent/IS8223A/is unknown
Also Published As
Publication number | Publication date |
---|---|
CN1819996B (zh) | 2010-10-27 |
RU2363696C2 (ru) | 2009-08-10 |
WO2005007631A1 (fr) | 2005-01-27 |
EP1654236A1 (fr) | 2006-05-10 |
KR20060052799A (ko) | 2006-05-19 |
UA87822C2 (ru) | 2009-08-25 |
JP4832295B2 (ja) | 2011-12-07 |
SG144941A1 (en) | 2008-08-28 |
MXPA06000401A (es) | 2006-03-17 |
AU2004257257B2 (en) | 2011-05-12 |
IL172812A0 (en) | 2006-06-11 |
CN1819996A (zh) | 2006-08-16 |
BRPI0412424A (pt) | 2006-09-05 |
RU2006103996A (ru) | 2006-07-10 |
NO20060114L (no) | 2006-02-09 |
JP2007523866A (ja) | 2007-08-23 |
AU2004257257A1 (en) | 2005-01-27 |
IS8223A (is) | 2006-01-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2532078A1 (fr) | Derives de naphtylene constituant des inhibiteurs du cytochrome p450 | |
US7994204B2 (en) | Binding inhibitor of sphingosine-1-phosphate | |
AU2012328034B2 (en) | (4-phenylimidazol-2-yl) ethylamine derivatives useful as sodium channel modulators | |
EP2368887B1 (fr) | Dérivés de 1,2,3-triazole destinés à être utilisés comme inhibiteurs de la stéaroyl-coa désaturase | |
US7662844B2 (en) | Naphthylene derivatives as cytochrome P450 inhibitors | |
AU2008247102A1 (en) | 2 -pyridine carboxamide derivatives as sodium channel modulators | |
EP1442034A1 (fr) | Derives de benzimidazoles et leur utilisation comme inhibiteurs de proteine kinase kdr | |
WO2004022523A2 (fr) | Derives de promedicaments a base de 1, 3-diamino-2-hydroxypropane | |
FR2542315A1 (fr) | Nouveaux composes azoliques, leur preparation et leur utilisation comme antifongiques et fongicides | |
CA2126972C (fr) | Derive du styrene et ses sels | |
AU758246B2 (en) | N,N-substituted cyclic amine derivatives | |
KR20010101730A (ko) | 매트릭스 금속단백질분해효소 억제제로서의2,3,4,5-테트라하이드로-1에이치-[1,4]벤조디아제핀-3-하이드록삼산 | |
CA2893239A1 (fr) | Composes de triazole et d'imidazole substitues | |
JP3415865B2 (ja) | 光学活性アゾール化合物およびその用途 | |
WO1996031491A1 (fr) | Agent antifongique de triazole | |
CZ72095A3 (en) | Benzenealkanoic acids as such and for use in medicine, process of their preparation and their use for the preparation of medicaments and pharmaceutical preparations based thereon | |
CN109195947B (zh) | 安眠蛋白α和β的新型抑制剂 | |
KR20030025931A (ko) | 2-아미노티아졸린 유도체 및 no-신타제 억제제로서의이의 용도 | |
AU2017224343A1 (en) | Novel pyrrolidine derivatives | |
US7288541B2 (en) | Propylcarbamate derivatives as inhibitors of serine and cysteine proteases | |
WO1998033778A1 (fr) | Derives triazole | |
OA16888A (en) | (4-phenylimidazol-2-YL) ethylamine derivatives useful as sodium channel modulators | |
JPH07291965A (ja) | 新規なピロリジン誘導体 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued |