CA2513572A1 - Treatment of benign prostatic hyperplasia - Google Patents
Treatment of benign prostatic hyperplasia Download PDFInfo
- Publication number
- CA2513572A1 CA2513572A1 CA002513572A CA2513572A CA2513572A1 CA 2513572 A1 CA2513572 A1 CA 2513572A1 CA 002513572 A CA002513572 A CA 002513572A CA 2513572 A CA2513572 A CA 2513572A CA 2513572 A1 CA2513572 A1 CA 2513572A1
- Authority
- CA
- Canada
- Prior art keywords
- lonidamine
- bph
- treatment
- administered
- analog
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/342—Prostate diseases, e.g. BPH, prostatitis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44111003P | 2003-01-17 | 2003-01-17 | |
| US60/441,110 | 2003-01-17 | ||
| US44234403P | 2003-01-23 | 2003-01-23 | |
| US60/442,344 | 2003-01-23 | ||
| US45866503P | 2003-03-28 | 2003-03-28 | |
| US45884603P | 2003-03-28 | 2003-03-28 | |
| US45866303P | 2003-03-28 | 2003-03-28 | |
| US60/458,665 | 2003-03-28 | ||
| US60/458,846 | 2003-03-28 | ||
| US60/458,663 | 2003-03-28 | ||
| US46001203P | 2003-04-02 | 2003-04-02 | |
| US60/460,012 | 2003-04-02 | ||
| US47290703P | 2003-05-22 | 2003-05-22 | |
| US60/472,907 | 2003-05-22 | ||
| US48826503P | 2003-07-18 | 2003-07-18 | |
| US60/488,265 | 2003-07-18 | ||
| US49616303P | 2003-08-18 | 2003-08-18 | |
| US60/496,163 | 2003-08-18 | ||
| PCT/US2004/001141 WO2004064735A2 (en) | 2003-01-17 | 2004-01-16 | Treatment of benign prostatic hyperplasia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2513572A1 true CA2513572A1 (en) | 2004-08-05 |
Family
ID=32777423
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002513575A Abandoned CA2513575A1 (en) | 2003-01-17 | 2004-01-16 | Treatment of benign prostatic hyperplasia using energolytic agents |
| CA002513572A Abandoned CA2513572A1 (en) | 2003-01-17 | 2004-01-16 | Treatment of benign prostatic hyperplasia |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002513575A Abandoned CA2513575A1 (en) | 2003-01-17 | 2004-01-16 | Treatment of benign prostatic hyperplasia using energolytic agents |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US6989400B2 (enExample) |
| EP (2) | EP1592430A4 (enExample) |
| JP (2) | JP2006518343A (enExample) |
| KR (2) | KR20050098249A (enExample) |
| AU (2) | AU2004206870A1 (enExample) |
| BR (1) | BRPI0406796A (enExample) |
| CA (2) | CA2513575A1 (enExample) |
| DE (1) | DE04702967T1 (enExample) |
| ES (1) | ES2254046T1 (enExample) |
| IL (1) | IL169685A0 (enExample) |
| MX (2) | MXPA05007572A (enExample) |
| NO (1) | NO20053783L (enExample) |
| WO (2) | WO2004064735A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7795227B2 (en) | 2004-06-17 | 2010-09-14 | Wisconsin Alumni Research Foundation | Compounds and methods for treating seizure disorders |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7547673B2 (en) * | 2001-09-13 | 2009-06-16 | The Johns Hopkins University | Therapeutics for cancer using 3-bromopyruvate and other selective inhibitors of ATP production |
| US7524885B2 (en) * | 2002-04-01 | 2009-04-28 | The Governors Of The University Of Alberta | Compounds that stimulate glucose utilization and methods of use |
| AU2004206870A1 (en) | 2003-01-17 | 2004-08-05 | Threshold Pharmaceuticals, Inc. | Treatment of benign prostatic hyperplasia using energolytic agents |
| US7208611B2 (en) | 2005-02-23 | 2007-04-24 | Xenoport, Inc. | Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use |
| US20060287253A1 (en) * | 2005-06-17 | 2006-12-21 | Kriegler Steven M | Compounds and methods for treating seizure disorders |
| US8324175B2 (en) * | 2006-02-16 | 2012-12-04 | Young Hee Ko | Compositions and methods for the treatment of cancer |
| KR20080096807A (ko) * | 2006-02-24 | 2008-11-03 | 보오드 오브 리젠츠, 더 유니버시티 오브 텍사스 시스템 | 암 치료용 6탄당 화합물 |
| KR20080114711A (ko) | 2006-03-02 | 2008-12-31 | 아스텔라스세이야쿠 가부시키가이샤 | 17β ＨＳＤ 타입 5 저해제 |
| WO2008076964A1 (en) * | 2006-12-18 | 2008-06-26 | The Johns Hopkins University | Therapeutics for cancer using 3-bromopyruvate and other selective inhibitors of atp production |
| US20080245375A1 (en) * | 2007-04-05 | 2008-10-09 | Medtronic Vascular, Inc. | Benign Prostatic Hyperplasia Treatments |
| MX2010000918A (es) | 2007-07-24 | 2010-03-15 | Astellas Pharma Inc | Derivado de bencimidazol. |
| AU2008292420A1 (en) | 2007-08-31 | 2009-03-05 | Astellas Pharma Inc. | Piperidine derivative |
| US8603123B2 (en) | 2008-04-28 | 2013-12-10 | Urotech, Inc. | Benign prostatic hyperplasia surgical system featuring mechanical coring probe with live aspiration |
| WO2010021750A2 (en) | 2008-08-21 | 2010-02-25 | The Johns Hopkins University | Methods and compositions for administration of 3-halopyruvate and related compounds for the treatment of cancer |
| WO2010088564A2 (en) * | 2009-01-29 | 2010-08-05 | Young Hee Ko | Compositions and methods for the treatment of cancer |
| JPWO2013153821A1 (ja) * | 2012-04-12 | 2015-12-17 | 学校法人北里研究所 | Ｐｄｋ４阻害剤及びその利用 |
| US10441561B2 (en) | 2012-07-26 | 2019-10-15 | The William M. Yanbrough Foundation | Method for treating benign prostatic hyperplasia (BPH), prostatitis, and prostate cancer |
| JP6552509B2 (ja) | 2014-01-14 | 2019-07-31 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 選択的ａｔｐ阻害剤をカプセル化するシクロデキストリン組成物およびその使用 |
| US10751306B2 (en) | 2015-11-06 | 2020-08-25 | The Johns Hopkins University | Methods of treating liver fibrosis by administering 3-bromopyruvate |
| EP3564214B1 (en) | 2018-05-04 | 2024-07-03 | Universita' Degli Studi G. D'annunzio Chieti - Pescara | Indazole derivatives as modulators of the cannabinoid system |
| EP4213839A4 (en) * | 2020-09-17 | 2024-08-07 | Escient Pharmaceuticals, Inc. | MODULATORS OF THE MAS-RELATED G-PROTEIN RECEPTOR X4 AND RELATED PRODUCTS AND METHODS |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1052111B (it) | 1972-02-29 | 1981-06-20 | Acraf | Acidi i benzil i h indazol 3 carbossilici sostituiti e loro derivati |
| US4684627A (en) | 1981-09-08 | 1987-08-04 | Leveen Harry H | Treatment of cancer with phlorizin and its derivatives |
| CA1289077C (en) | 1984-08-13 | 1991-09-17 | Harry H. Leveen | Treatment of cancer with phlorizin and its derivatives |
| US5260327A (en) * | 1985-10-02 | 1993-11-09 | Sloan-Kettering Institute For Cancer Research | Methods for inhibiting the proliferation of brain and hepatic metastases by using lonidamine |
| WO1992018132A1 (en) * | 1991-04-17 | 1992-10-29 | Merck & Co., Inc. | Pharmaceutical combination for the treatment of benign prostatic hyperplasia comtaining a 5 alpha-reductase inhibitor |
| US6063911A (en) * | 1993-12-01 | 2000-05-16 | Marine Polymer Technologies, Inc. | Methods and compositions for treatment of cell proliferative disorders |
| US5654320A (en) * | 1995-03-16 | 1997-08-05 | Eli Lilly And Company | Indazolecarboxamides |
| ATE247469T1 (de) | 1995-06-07 | 2003-09-15 | Pfizer | Heterocyclische kondensierte pyrimidin-derivate |
| FR2737721B1 (fr) | 1995-08-08 | 1997-09-05 | Roussel Uclaf | Nouveaux composes biphenyles, leur procede de preparation et les intermediaires de ce procede, leur application a titre de medicament et les compositions pharmaceutiques les contenant |
| EP0797564B1 (en) | 1995-10-18 | 2001-06-27 | Kanoldt Arzneimittel Gmbh | Lignans, a process for their production and pharmaceutical compositions and uses thereof |
| DE19621319A1 (de) | 1996-05-28 | 1997-12-04 | Hoechst Ag | Bis-ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| US6054432A (en) | 1996-09-12 | 2000-04-25 | Asta Medica Aktiengesellschaft | Means for treating prostate hypertrophy and prostate cancer |
| IT1289938B1 (it) | 1997-02-20 | 1998-10-19 | Angelini Ricerche Spa | Preparazione farmaceutica comprendente liposomi liofilizzati in cui e' incapsulato un principio attivo altamente insolubile in acqua e |
| IT1289939B1 (it) | 1997-02-20 | 1998-10-19 | Angelini Ricerche Spa | Composizione farmaceutica acquosa comprendente un principio attivo altamente insolubile in acqua |
| CN1078462C (zh) * | 1997-07-09 | 2002-01-30 | 辛国芳 | 棉酚和/或其衍生物作为有效成分在制备用于治疗前列腺炎的栓剂中的应用 |
| US6482802B1 (en) * | 1998-05-11 | 2002-11-19 | Endowment For Research In Human Biology, Inc. | Use of neomycin for treating angiogenesis-related diseases |
| US6428968B1 (en) * | 1999-03-15 | 2002-08-06 | The Trustees Of The University Of Pennsylvania | Combined therapy with a chemotherapeutic agent and an oncolytic virus for killing tumor cells in a subject |
| US6001865A (en) * | 1999-05-04 | 1999-12-14 | Angelini Pharmaceuticals Inc. | 3-substituted 1-benzyl-1H-indazole derivatives as antifertility agents |
| AU2004206870A1 (en) | 2003-01-17 | 2004-08-05 | Threshold Pharmaceuticals, Inc. | Treatment of benign prostatic hyperplasia using energolytic agents |
| KR20080097496A (ko) * | 2004-03-25 | 2008-11-05 | 더 리젠츠 오브 더 유니버시티 오브 미시간 | 고시폴 공결정 및 그의 용도 |
-
2004
- 2004-01-16 AU AU2004206870A patent/AU2004206870A1/en not_active Abandoned
- 2004-01-16 EP EP04702976A patent/EP1592430A4/en not_active Withdrawn
- 2004-01-16 US US10/759,337 patent/US6989400B2/en not_active Expired - Fee Related
- 2004-01-16 AU AU2004206869A patent/AU2004206869A1/en not_active Abandoned
- 2004-01-16 WO PCT/US2004/001141 patent/WO2004064735A2/en not_active Ceased
- 2004-01-16 MX MXPA05007572A patent/MXPA05007572A/es unknown
- 2004-01-16 ES ES04702967T patent/ES2254046T1/es active Pending
- 2004-01-16 JP JP2006500983A patent/JP2006518343A/ja not_active Withdrawn
- 2004-01-16 DE DE04702967T patent/DE04702967T1/de active Pending
- 2004-01-16 MX MXPA05007571A patent/MXPA05007571A/es unknown
- 2004-01-16 KR KR1020057013198A patent/KR20050098249A/ko not_active Withdrawn
- 2004-01-16 CA CA002513575A patent/CA2513575A1/en not_active Abandoned
- 2004-01-16 EP EP04702967A patent/EP1610778A4/en not_active Withdrawn
- 2004-01-16 JP JP2006500981A patent/JP2006516571A/ja active Pending
- 2004-01-16 KR KR1020057013200A patent/KR20050098250A/ko not_active Withdrawn
- 2004-01-16 BR BR0406796-7A patent/BRPI0406796A/pt not_active Application Discontinuation
- 2004-01-16 CA CA002513572A patent/CA2513572A1/en not_active Abandoned
- 2004-01-16 WO PCT/US2004/001146 patent/WO2004064736A2/en not_active Ceased
-
2005
- 2005-06-29 US US11/171,020 patent/US20050272795A1/en not_active Abandoned
- 2005-06-29 US US11/172,050 patent/US20050271723A1/en not_active Abandoned
- 2005-06-29 US US11/171,138 patent/US20050272796A1/en not_active Abandoned
- 2005-07-14 IL IL169685A patent/IL169685A0/en unknown
- 2005-08-09 NO NO20053783A patent/NO20053783L/no unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7795227B2 (en) | 2004-06-17 | 2010-09-14 | Wisconsin Alumni Research Foundation | Compounds and methods for treating seizure disorders |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004064736A3 (en) | 2005-05-06 |
| EP1610778A2 (en) | 2006-01-04 |
| AU2004206870A1 (en) | 2004-08-05 |
| MXPA05007572A (es) | 2005-11-17 |
| AU2004206869A1 (en) | 2004-08-05 |
| NO20053783D0 (no) | 2005-08-09 |
| KR20050098250A (ko) | 2005-10-11 |
| CA2513575A1 (en) | 2004-08-05 |
| DE04702967T1 (de) | 2006-06-22 |
| WO2004064735A3 (en) | 2004-12-16 |
| ES2254046T1 (es) | 2006-06-16 |
| US20050271723A1 (en) | 2005-12-08 |
| US20050272795A1 (en) | 2005-12-08 |
| EP1610778A4 (en) | 2006-05-31 |
| NO20053783L (no) | 2005-09-27 |
| MXPA05007571A (es) | 2005-11-17 |
| KR20050098249A (ko) | 2005-10-11 |
| US6989400B2 (en) | 2006-01-24 |
| JP2006518343A (ja) | 2006-08-10 |
| US20050272796A1 (en) | 2005-12-08 |
| US20040167196A1 (en) | 2004-08-26 |
| WO2004064735A2 (en) | 2004-08-05 |
| WO2004064736A2 (en) | 2004-08-05 |
| EP1592430A2 (en) | 2005-11-09 |
| EP1592430A4 (en) | 2006-05-31 |
| IL169685A0 (en) | 2007-07-04 |
| BRPI0406796A (pt) | 2006-01-17 |
| JP2006516571A (ja) | 2006-07-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |