CA2509632A1 - Me-5, me-2, and epp2: human protein antigens reactive with autoantibodies present in the serum of woman suffering from endometriosis - Google Patents

Me-5, me-2, and epp2: human protein antigens reactive with autoantibodies present in the serum of woman suffering from endometriosis Download PDF

Info

Publication number
CA2509632A1
CA2509632A1 CA002509632A CA2509632A CA2509632A1 CA 2509632 A1 CA2509632 A1 CA 2509632A1 CA 002509632 A CA002509632 A CA 002509632A CA 2509632 A CA2509632 A CA 2509632A CA 2509632 A1 CA2509632 A1 CA 2509632A1
Authority
CA
Canada
Prior art keywords
seq
endometriosis
polypeptide
epp2
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002509632A
Other languages
English (en)
French (fr)
Inventor
A. Said El Shami
Bruce A. Campbell
Dennis Sustarsic
Niver P. Sahakian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics Inc
Original Assignee
Diagnostic Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diagnostic Products Corp filed Critical Diagnostic Products Corp
Publication of CA2509632A1 publication Critical patent/CA2509632A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/364—Endometriosis, i.e. non-malignant disorder in which functioning endometrial tissue is present outside the uterine cavity
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/811—Drug, bio-affecting and body treating compositions involving sex selection or contraception
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/85—Reproductive organs or embryos
    • Y10S530/852—Sperm
    • Y10S530/853—Ovary; eggs; embryos
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Diabetes (AREA)
  • General Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
CA002509632A 2004-07-07 2005-07-05 Me-5, me-2, and epp2: human protein antigens reactive with autoantibodies present in the serum of woman suffering from endometriosis Abandoned CA2509632A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/887,540 2004-07-07
US10/887,540 US20060008876A1 (en) 2004-07-07 2004-07-07 ME-5, ME-2, and EPP2: human protein antigens reactive with autoantibodies present in the serum of women suffering from endometriosis

Publications (1)

Publication Number Publication Date
CA2509632A1 true CA2509632A1 (en) 2006-01-07

Family

ID=35124497

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002509632A Abandoned CA2509632A1 (en) 2004-07-07 2005-07-05 Me-5, me-2, and epp2: human protein antigens reactive with autoantibodies present in the serum of woman suffering from endometriosis

Country Status (9)

Country Link
US (7) US20060008876A1 (enExample)
EP (1) EP1614692B1 (enExample)
JP (1) JP2006051019A (enExample)
AT (1) ATE433462T1 (enExample)
AU (1) AU2005202925A1 (enExample)
CA (1) CA2509632A1 (enExample)
DE (1) DE602005014828D1 (enExample)
ES (1) ES2326324T3 (enExample)
NZ (1) NZ541063A (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2087152B1 (en) * 2006-10-27 2015-03-11 Walfish, Paul Endometrial biomarkers
US8279789B2 (en) * 2008-06-10 2012-10-02 Qualcomm Incorporated Intelligent setting of hysteresis activation timer to enter hysteresis sooner and save battery
US20110171291A1 (en) * 2010-01-07 2011-07-14 Sanford-Burnham Medical Research Institute Pathologically-activated therapeutics
DE102012002929A1 (de) 2012-02-14 2013-08-14 Jürgen Lewald Minimalinvasives Verfahren für die Diagnose und die Therapieverlaufskontrolle der Endometriose
GB202310300D0 (en) 2023-07-05 2023-08-16 Univ Edinburgh Endometrosis markers and methods of diagnosing nedometriosis

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US652187A (en) * 1899-11-02 1900-06-19 Sigvald Krohn System of electrical distribution.
US4489166A (en) * 1982-05-27 1984-12-18 Research Corporation Monitoring of human endometrial function by radioimmunoassay of PEP
NZ232801A (en) 1989-03-07 1992-01-29 Adeza Biomedical Corp Diagnostic test for endometriosis
JP3204668B2 (ja) 1991-03-15 2001-09-04 エフ・ホフマン―ラ ロシユ アーゲー キラルなホスフイン
CA2062675A1 (en) 1991-04-09 1992-10-10 Sandra S. Fenton Endometrial antigen, composition, test kit and method for endometrial antibody determination
AU6960694A (en) * 1993-05-28 1994-12-20 Medical University Of South Carolina Endometrial proteins, antigenic compositions and methods for detecting endometriosis
US5877284A (en) * 1993-08-12 1999-03-02 The Trustees Of The University Of Pennsylvania Isolated chemotactic factor from patients with endometriosis
US7122322B2 (en) * 1994-10-25 2006-10-17 The Curators Of The University Of Missouri Endometriosis-specific secretory protein
US5843673A (en) * 1994-10-25 1998-12-01 Curators Of The University Of Missouri Method of screening for endometriosis
US6531277B2 (en) * 1994-10-25 2003-03-11 The Curators Of The University Of Missouri Endometriosis-specific secretory protein
US5618680A (en) * 1994-12-28 1997-04-08 Institut De Medecine De La Reproduction De Montreal Use of ligands specific to major histocompatibility complex-class I antigens for diagnosing endometriosis
US6376201B2 (en) * 1994-12-28 2002-04-23 Procrea Biosciences Inc. Use of ligands specific to major histocompatibility complex-class I antigens for diagnosing endometriosis
AU2077197A (en) 1996-03-18 1997-10-10 Novo Nordisk Biotech, Inc. Polypeptides having phytase activity and nucleic acids encoding same
WO1997035018A1 (en) 1996-03-21 1997-09-25 New York University Growth factor inducible serine/threonine phosphatase fin13
US6294662B1 (en) * 1996-08-27 2001-09-25 University Of South Florida Nucleic acids encoding an endometrial bleeding associated factor (ebaf)
JP2001516009A (ja) 1997-07-17 2001-09-25 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ ガン関連核酸及びポリペプチド
US6165767A (en) * 1998-03-20 2000-12-26 Incyte Pharmaceuticals, Inc. Protein phosphatase-related molecules
EP1076723A2 (en) * 1998-06-04 2001-02-21 Reprogen, Inc. Use of cathepsin s in the diagnosis and treatment of endometriosis
AU760613B2 (en) 1998-06-04 2003-05-22 Reprogen, Inc. Use of prothymosin in the diagnosis and treatment of endometriosis
US6525187B1 (en) * 1998-07-31 2003-02-25 Diagnostic Products Corporation Polynucleotide encoding autoantigens associated with endometriosis
NZ513692A (en) 1999-01-25 2001-09-28 Procrea Biosciences Inc Method and diagnostic kit for diagnosis of endometriosis
JP2002541124A (ja) * 1999-04-02 2002-12-03 センター・フォー・モレキュラー・メディシン・アンド・イムノロジー 子宮内膜症を検出する方法
WO2000063675A1 (en) 1999-04-16 2000-10-26 Bioincept, Inc. Identification of a serum marker for endometriosis
WO2000075321A2 (en) * 1999-06-03 2000-12-14 Curagen Corporation Polynucleotides and membrane-bound polypeptide encoded thereby
AU1159601A (en) 1999-11-03 2001-05-14 Metris Therapeutics Limited Agents implicated in endometriosis
GB0004232D0 (en) 2000-02-24 2000-04-12 Zeneca Ltd Diagnostic method
US6777182B2 (en) * 2000-02-25 2004-08-17 Metriogene Biosciences Inc. Methods for determining the likelihood of endometriosis in a female subject
CA2406496A1 (en) * 2000-04-19 2001-11-01 Research Corporation Technologies, Inc. Diagnostic assay for endometriosis
US20010044158A1 (en) * 2000-04-19 2001-11-22 Yeaman Grant R. Diagnostic assay for endometriosis
DE10048633A1 (de) 2000-09-25 2002-04-18 Schering Ag Methode zur in vitro Diagnostik von Endometriose
US6780594B2 (en) * 2000-09-25 2004-08-24 Schering Aktiengesellschaft Method for in vitro diagnosis of endometriosis
WO2002068579A2 (en) 2001-01-10 2002-09-06 Pe Corporation (Ny) Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof
US7049069B2 (en) * 2001-07-17 2006-05-23 University Of Florida Detecting and treating reproductive tract disorders
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WO2004087874A2 (en) 2003-03-28 2004-10-14 Nuvelo, Inc. Novel nucleic acids and polypeptides
WO2005019258A2 (en) * 2003-08-11 2005-03-03 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
US6843673B1 (en) * 2004-04-30 2005-01-18 Speed Tech Corp. Coaxial connector structure

Also Published As

Publication number Publication date
US20100062453A1 (en) 2010-03-11
EP1614692A2 (en) 2006-01-11
EP1614692A3 (en) 2006-04-05
AU2005202925A1 (en) 2006-02-02
US20060008876A1 (en) 2006-01-12
NZ541063A (en) 2008-07-31
ATE433462T1 (de) 2009-06-15
US20100330696A1 (en) 2010-12-30
US20070141600A1 (en) 2007-06-21
US20110201129A1 (en) 2011-08-18
DE602005014828D1 (de) 2009-07-23
EP1614692B1 (en) 2009-06-10
ES2326324T3 (es) 2009-10-07
US7981626B2 (en) 2011-07-19
US20080153106A1 (en) 2008-06-26
US7879562B2 (en) 2011-02-01
US8030007B2 (en) 2011-10-04
JP2006051019A (ja) 2006-02-23
US20070178528A1 (en) 2007-08-02

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued