CA2465800C - Instrument - Google Patents

Instrument Download PDF

Info

Publication number
CA2465800C
CA2465800C CA002465800A CA2465800A CA2465800C CA 2465800 C CA2465800 C CA 2465800C CA 002465800 A CA002465800 A CA 002465800A CA 2465800 A CA2465800 A CA 2465800A CA 2465800 C CA2465800 C CA 2465800C
Authority
CA
Canada
Prior art keywords
blood
concentration
measurement
glucose
control
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002465800A
Other languages
English (en)
French (fr)
Other versions
CA2465800A1 (en
Inventor
Zindel Herbert Heller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoffmann La Roche Inc
Original Assignee
Hoffmann La Roche Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche Inc filed Critical Hoffmann La Roche Inc
Publication of CA2465800A1 publication Critical patent/CA2465800A1/en
Application granted granted Critical
Publication of CA2465800C publication Critical patent/CA2465800C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y10T436/144444—Glucose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Ecology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
CA002465800A 2001-11-07 2002-11-07 Instrument Expired - Lifetime CA2465800C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/046,030 2001-11-07
US10/046,030 US7018843B2 (en) 2001-11-07 2001-11-07 Instrument
PCT/EP2002/012422 WO2003040728A2 (en) 2001-11-07 2002-11-07 Method and apparatus for the determination of glucose

Publications (2)

Publication Number Publication Date
CA2465800A1 CA2465800A1 (en) 2003-05-15
CA2465800C true CA2465800C (en) 2009-09-01

Family

ID=21941198

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002465800A Expired - Lifetime CA2465800C (en) 2001-11-07 2002-11-07 Instrument

Country Status (5)

Country Link
US (3) US7018843B2 (enExample)
EP (1) EP1456666B1 (enExample)
JP (2) JP4180518B2 (enExample)
CA (1) CA2465800C (enExample)
WO (1) WO2003040728A2 (enExample)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071384B2 (en) 1997-12-22 2011-12-06 Roche Diagnostics Operations, Inc. Control and calibration solutions and methods for their use
US7407811B2 (en) * 1997-12-22 2008-08-05 Roche Diagnostics Operations, Inc. System and method for analyte measurement using AC excitation
US7494816B2 (en) * 1997-12-22 2009-02-24 Roche Diagnostic Operations, Inc. System and method for determining a temperature during analyte measurement
US7390667B2 (en) * 1997-12-22 2008-06-24 Roche Diagnostics Operations, Inc. System and method for analyte measurement using AC phase angle measurements
EP2151683A3 (en) 1999-11-15 2010-07-28 Panasonic Corporation Biosensor, thin film electrode forming method, quantification apparatus, and quantification method
EP2096437B1 (en) 2000-11-30 2014-11-19 Panasonic Healthcare Co., Ltd. Biosensor for quantifying substrate
US7195923B2 (en) * 2001-01-31 2007-03-27 Scripps Laboratories, Inc. Ratiometric determination of glycated protein
US7018843B2 (en) * 2001-11-07 2006-03-28 Roche Diagnostics Operations, Inc. Instrument
US7452457B2 (en) 2003-06-20 2008-11-18 Roche Diagnostics Operations, Inc. System and method for analyte measurement using dose sufficiency electrodes
US7597793B2 (en) 2003-06-20 2009-10-06 Roche Operations Ltd. System and method for analyte measurement employing maximum dosing time delay
US7488601B2 (en) * 2003-06-20 2009-02-10 Roche Diagnostic Operations, Inc. System and method for determining an abused sensor during analyte measurement
US8148164B2 (en) 2003-06-20 2012-04-03 Roche Diagnostics Operations, Inc. System and method for determining the concentration of an analyte in a sample fluid
EP2579031B1 (en) 2003-12-04 2017-09-27 Panasonic Healthcare Holdings Co., Ltd. Biosensor for measuring blood component and hematocrit.
EP3285068B1 (en) * 2003-12-04 2020-02-12 PHC Holdings Corporation Method of electrochemically measuring hematocrit (hct)
BRPI0507376A (pt) 2004-02-06 2007-07-10 Bayer Healthcare Llc espécie oxidável como uma referência interna para biossensores e método de uso
CA2557690C (en) * 2004-03-31 2022-04-12 George A. Mecklenburg Method and apparatus for implementing threshold based correction functions for biosensors
WO2005103669A1 (ja) 2004-04-19 2005-11-03 Matsushita Electric Industrial Co., Ltd. 血液成分の測定方法、それに用いるバイオセンサおよび測定装置
JP5065013B2 (ja) * 2004-05-14 2012-10-31 バイエル・ヘルスケア・エルエルシー グルコースアッセイにおいてヘマトクリットの調整を行う方法、およびそのための装置
US7356366B2 (en) * 2004-08-02 2008-04-08 Cardiac Pacemakers, Inc. Device for monitoring fluid status
US7344626B2 (en) * 2005-04-15 2008-03-18 Agamatrix, Inc. Method and apparatus for detection of abnormal traces during electrochemical analyte detection
US20070129618A1 (en) * 2005-06-20 2007-06-07 Daniel Goldberger Blood parameter testing system
BRPI0613592A2 (pt) 2005-07-20 2011-01-18 Bayer Healthcare Llc amperometria conectada por porta
WO2007040913A1 (en) 2005-09-30 2007-04-12 Bayer Healthcare Llc Gated voltammetry
EP2184348B1 (en) * 2006-03-23 2013-11-27 Ajinomoto Co., Inc. A method for producing an L-amino acid using bacterium of the Enterobacteriaceae family with attenuated expression of a gene coding for small RNA
US8529751B2 (en) 2006-03-31 2013-09-10 Lifescan, Inc. Systems and methods for discriminating control solution from a physiological sample
BRPI0716296B1 (pt) 2006-11-01 2019-01-15 Dow Global Technologies Inc composição, artigo, estrutura laminada, dispersão, artigo moldado por injeção, artigo moldado, artigo para calçados e peça automotiva
WO2009015316A1 (en) * 2007-07-26 2009-01-29 Home Diagnostics, Inc, System and methods for determination of analyte concentration using time resolved amperometry
US8101062B2 (en) * 2007-07-26 2012-01-24 Nipro Diagnostics, Inc. System and methods for determination of analyte concentration using time resolved amperometry
US8778168B2 (en) 2007-09-28 2014-07-15 Lifescan, Inc. Systems and methods of discriminating control solution from a physiological sample
WO2009076302A1 (en) 2007-12-10 2009-06-18 Bayer Healthcare Llc Control markers for auto-detection of control solution and methods of use
US8603768B2 (en) * 2008-01-17 2013-12-10 Lifescan, Inc. System and method for measuring an analyte in a sample
EP2241883A4 (en) * 2008-01-22 2014-10-29 Univ Nat Chonnam Ind Found METHOD AND DEVICE FOR ASSESSING THE CHARACTERISTICS OF TARGET MATERIALS USING INFORMATION ABOUT KINETIC CHANGES
JP5427362B2 (ja) * 2008-03-25 2014-02-26 テルモ株式会社 ヘマトクリット値または血液成分濃度の測定方法および測定装置
US8551320B2 (en) * 2008-06-09 2013-10-08 Lifescan, Inc. System and method for measuring an analyte in a sample
WO2010006253A1 (en) 2008-07-10 2010-01-14 Bayer Healthcare Llc Systems and methods including amperometric and voltammetric duty cycles
GB0814238D0 (en) * 2008-08-04 2008-09-10 Oxford Biosensors Ltd Enhancement of electrochemical response
US8760178B2 (en) 2009-09-30 2014-06-24 Arkray, Inc. Method for measuring target component in erythrocyte-containing specimen
JP5350960B2 (ja) * 2009-09-30 2013-11-27 アークレイ株式会社 赤血球含有試料における目的成分の測定方法
US8877034B2 (en) * 2009-12-30 2014-11-04 Lifescan, Inc. Systems, devices, and methods for measuring whole blood hematocrit based on initial fill velocity
US8101065B2 (en) * 2009-12-30 2012-01-24 Lifescan, Inc. Systems, devices, and methods for improving accuracy of biosensors using fill time
US8617370B2 (en) 2010-09-30 2013-12-31 Cilag Gmbh International Systems and methods of discriminating between a control sample and a test fluid using capacitance
US8932445B2 (en) 2010-09-30 2015-01-13 Cilag Gmbh International Systems and methods for improved stability of electrochemical sensors
TWI470226B (zh) * 2011-03-01 2015-01-21 Eps Bio Technology Corp 補償血糖濃度的方法
EP2607492A1 (de) * 2011-12-22 2013-06-26 Roche Diagniostics GmbH Verfahren zur Bestimmung einer Analytkonzentration
US9903830B2 (en) 2011-12-29 2018-02-27 Lifescan Scotland Limited Accurate analyte measurements for electrochemical test strip based on sensed physical characteristic(s) of the sample containing the analyte
EP3385706A1 (en) 2013-03-15 2018-10-10 Roche Diabetes Care GmbH Methods of scaling data used to construct biosensor algorithms as well as devices, apparatuses and systems incorporating the same
CA2900572C (en) 2013-03-15 2018-02-13 F. Hoffmann-La Roche Ag Methods of detecting high antioxidant levels during electrochemical measurements and failsafing an analyte concentration therefrom as well as devices, apparatuses and systems incorporting the same
CN105283757B (zh) 2013-03-15 2019-04-23 豪夫迈·罗氏有限公司 对分析物的电化学测量进行防故障的方法以及结合该方法的设备、装置和系统
WO2014140164A1 (en) 2013-03-15 2014-09-18 Roche Diagnostics Gmbh Methods of using information from recovery pulses in electrochemical analyte measurements as well as devices, apparatuses and systems incorporating the same
US9243276B2 (en) 2013-08-29 2016-01-26 Lifescan Scotland Limited Method and system to determine hematocrit-insensitive glucose values in a fluid sample
US9459231B2 (en) 2013-08-29 2016-10-04 Lifescan Scotland Limited Method and system to determine erroneous measurement signals during a test measurement sequence
TWI586333B (zh) * 2013-09-06 2017-06-11 A blood volume detecting method and a detecting device using the same
WO2015178924A1 (en) * 2014-05-23 2015-11-26 Nova Biomedical Corporation Hemolysis detection method and system
EP3216076B1 (en) 2014-11-03 2024-03-06 F. Hoffmann-La Roche AG Method of using electrochemical test elements having multiple electrode arrangements
US9903832B2 (en) 2015-04-28 2018-02-27 Industrial Technology Research Institute Methods for measuring analyte concentration
TWI591330B (zh) 2016-06-06 2017-07-11 盛群半導體股份有限公司 血球容積比的全血量測方法及其全血量測電路
PL3523639T3 (pl) 2016-10-05 2025-03-17 F. Hoffmann-La Roche Ag Odczynniki wykrywające i układy elektrod do elementów diagnostycznych testów wieloanalitowych oraz sposoby ich zastosowania
CA3041623A1 (en) 2016-10-24 2018-05-03 F. Hoffmann-La Roche Ag Methods of correcting for uncompensated resistances in the conductive elements of biosensors, as well as devices and systems

Family Cites Families (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB973807A (en) 1959-12-24 1964-10-28 Yellow Springs Instr Improvements in instruments for determining characteristics of blood
US3648159A (en) 1970-03-11 1972-03-07 Us Air Force Portable, self-contained system for analyzing biological fluids or the like
US3770607A (en) * 1970-04-07 1973-11-06 Secretary Glucose determination apparatus
CH559912A5 (enExample) * 1971-09-09 1975-03-14 Hoffmann La Roche
US3925183A (en) * 1972-06-16 1975-12-09 Energetics Science Gas detecting and quantitative measuring device
US3902970A (en) * 1973-07-30 1975-09-02 Leeds & Northrup Co Flow-through amperometric measuring system and method
CH585907A5 (enExample) * 1973-08-06 1977-03-15 Hoffmann La Roche
US3922598A (en) * 1974-08-15 1975-11-25 Robert R Steuer Hematocrit measurements by electrical conductivity
US3937615A (en) * 1974-12-17 1976-02-10 Leeds & Northrup Company Auto-ranging glucose measuring system
US4052596A (en) * 1974-12-23 1977-10-04 Hycel, Inc. Automatic hematology analyzer
US4230537A (en) * 1975-12-18 1980-10-28 Monsanto Company Discrete biochemical electrode system
US4040908A (en) * 1976-03-12 1977-08-09 Children's Hospital Medical Center Polarographic analysis of cholesterol and other macromolecular substances
US4123701A (en) * 1976-07-01 1978-10-31 United States Surgical Corporation Disposable sample card having a well with electrodes for testing a liquid sample
US4127448A (en) * 1977-02-28 1978-11-28 Schick Karl G Amperometric-non-enzymatic method of determining sugars and other polyhydroxy compounds
JPS5912135B2 (ja) * 1977-09-28 1984-03-21 松下電器産業株式会社 酵素電極
JPS5460996A (en) * 1977-10-22 1979-05-16 Mitsubishi Chem Ind Method of measuring amount of sugar
US4214968A (en) * 1978-04-05 1980-07-29 Eastman Kodak Company Ion-selective electrode
DE2817363C2 (de) * 1978-04-20 1984-01-26 Siemens AG, 1000 Berlin und 8000 München Verfahren zur Konzentrationsbestimmung von Zucker und dafür geeigneter elektrokatalytischer Zuckersensor
DE2823485C2 (de) * 1978-05-30 1986-03-27 Albert Prof. Dr. 3550 Marburg Huch Trogelektrode
US4240027A (en) * 1978-08-31 1980-12-16 The United States Of America As Represented By The Secretary Of The Army Electromagnetic method for the noninvasive analysis of cell membrane physiology and pharmacology
US4225410A (en) * 1978-12-04 1980-09-30 Technicon Instruments Corporation Integrated array of electrochemical sensors
US4273134A (en) * 1979-05-22 1981-06-16 Biochem International Inc. Fixation ring assembly and method of assembling a sensor head
US4265250A (en) * 1979-07-23 1981-05-05 Battle Research And Development Associates Electrode
US4263343A (en) * 1979-08-13 1981-04-21 Eastman Kodak Company Reference elements for ion-selective membrane electrodes
US4301414A (en) * 1979-10-29 1981-11-17 United States Surgical Corporation Disposable sample card and method of making same
US4303887A (en) * 1979-10-29 1981-12-01 United States Surgical Corporation Electrical liquid conductivity measuring system
US4301412A (en) * 1979-10-29 1981-11-17 United States Surgical Corporation Liquid conductivity measuring system and sample cards therefor
DE3029579C2 (de) * 1980-08-05 1985-12-12 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut
US4816224A (en) * 1980-08-05 1989-03-28 Boehringer Mannheim Gmbh Device for separating plasma or serum from whole blood and analyzing the same
US4407959A (en) * 1980-10-29 1983-10-04 Fuji Electric Co., Ltd. Blood sugar analyzing apparatus
US4413628A (en) * 1980-11-19 1983-11-08 Tamulis Walter G pH Monitor electrode electrolyte cartridge
US4420564A (en) * 1980-11-21 1983-12-13 Fuji Electric Company, Ltd. Blood sugar analyzer having fixed enzyme membrane sensor
DE3047782A1 (de) * 1980-12-18 1982-07-08 Drägerwerk AG, 2400 Lübeck Schaltungsanordnung zur korrektur der sensorausgangsgroesse
US4436094A (en) * 1981-03-09 1984-03-13 Evreka, Inc. Monitor for continuous in vivo measurement of glucose concentration
AT369254B (de) * 1981-05-07 1982-12-27 Otto Dipl Ing Dr Tech Prohaska Medizinische sonde
US4440175A (en) * 1981-08-10 1984-04-03 University Patents, Inc. Membrane electrode for non-ionic species
US4431004A (en) * 1981-10-27 1984-02-14 Bessman Samuel P Implantable glucose sensor
DE3202067C2 (de) 1982-01-23 1984-06-20 Holger Dr. 5100 Aachen Kiesewetter Vorrichtung zur Bestimmung des Hämatokritwertes
JPS5913948A (ja) * 1982-07-15 1984-01-24 Shimadzu Corp 静電容量式ヘマトクリツト測定装置
DE3228551A1 (de) * 1982-07-30 1984-02-02 Siemens AG, 1000 Berlin und 8000 München Verfahren zur bestimmung der zuckerkonzentration
DE3228542A1 (de) 1982-07-30 1984-02-02 Siemens AG, 1000 Berlin und 8000 München Verfahren zur bestimmung der konzentration elektrochemisch umsetzbarer stoffe
US4679562A (en) * 1983-02-16 1987-07-14 Cardiac Pacemakers, Inc. Glucose sensor
CA1219040A (en) * 1983-05-05 1987-03-10 Elliot V. Plotkin Measurement of enzyme-catalysed reactions
US5509410A (en) * 1983-06-06 1996-04-23 Medisense, Inc. Strip electrode including screen printing of a single layer
US4517291A (en) * 1983-08-15 1985-05-14 E. I. Du Pont De Nemours And Company Biological detection process using polymer-coated electrodes
SE8305704D0 (sv) * 1983-10-18 1983-10-18 Leo Ab Cuvette
US4820399A (en) * 1984-08-31 1989-04-11 Shimadzu Corporation Enzyme electrodes
US4671288A (en) * 1985-06-13 1987-06-09 The Regents Of The University Of California Electrochemical cell sensor for continuous short-term use in tissues and blood
US4897173A (en) * 1985-06-21 1990-01-30 Matsushita Electric Industrial Co., Ltd. Biosensor and method for making the same
US4938860A (en) * 1985-06-28 1990-07-03 Miles Inc. Electrode for electrochemical sensors
US4734184A (en) * 1985-08-29 1988-03-29 Diamond Sensor Systems, Inc. Self-activating hydratable solid-state electrode apparatus
US4805624A (en) * 1985-09-09 1989-02-21 The Montefiore Hospital Association Of Western Pa Low-potential electrochemical redox sensors
EP0215669A3 (en) * 1985-09-17 1989-08-30 Seiko Instruments Inc. Analytical device and method for analysis of biochemicals, microbes and cells
US4935106A (en) * 1985-11-15 1990-06-19 Smithkline Diagnostics, Inc. Ion selective/enzymatic electrode medical analyzer device and method of use
GB8608700D0 (en) 1986-04-10 1986-05-14 Genetics Int Inc Measurement of electroactive species in solution
US4795542A (en) * 1986-04-24 1989-01-03 St. Jude Medical, Inc. Electrochemical concentration detector device
US4703756A (en) * 1986-05-06 1987-11-03 The Regents Of The University Of California Complete glucose monitoring system with an implantable, telemetered sensor module
GB8612861D0 (en) * 1986-05-27 1986-07-02 Cambridge Life Sciences Immobilised enzyme biosensors
US4750496A (en) * 1987-01-28 1988-06-14 Xienta, Inc. Method and apparatus for measuring blood glucose concentration
JPS636451A (ja) * 1986-06-27 1988-01-12 Terumo Corp 酵素センサ
GB8618022D0 (en) 1986-07-23 1986-08-28 Unilever Plc Electrochemical measurements
US4935346A (en) * 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
JPS63111453A (ja) 1986-10-29 1988-05-16 Omron Tateisi Electronics Co 酵素電極
US4894137A (en) 1986-09-12 1990-01-16 Omron Tateisi Electronics Co. Enzyme electrode
US4897162A (en) * 1986-11-14 1990-01-30 The Cleveland Clinic Foundation Pulse voltammetry
JPS63128252A (ja) 1986-11-18 1988-05-31 Matsushita Electric Ind Co Ltd バイオセンサ
US4759828A (en) * 1987-04-09 1988-07-26 Nova Biomedical Corporation Glucose electrode and method of determining glucose
US4975647A (en) * 1987-06-01 1990-12-04 Nova Biomedical Corporation Controlling machine operation with respect to consumable accessory units
US5160980A (en) * 1987-07-27 1992-11-03 Boehringer Mannheim Corp. Test piece coloration comparative decision unit
US4940945A (en) * 1987-11-02 1990-07-10 Biologix Inc. Interface circuit for use in a portable blood chemistry measuring apparatus
AU601635B2 (en) * 1987-11-09 1990-09-13 Boehringer Mannheim Corporation Test sample color comparison device
US5108564A (en) * 1988-03-15 1992-04-28 Tall Oak Ventures Method and apparatus for amperometric diagnostic analysis
US5128015A (en) * 1988-03-15 1992-07-07 Tall Oak Ventures Method and apparatus for amperometric diagnostic analysis
US4871258A (en) * 1988-04-29 1989-10-03 Boehringer Mannheim Corporation Color test meter
US5053199A (en) * 1989-02-21 1991-10-01 Boehringer Mannheim Corporation Electronically readable information carrier
US5269891A (en) * 1989-03-09 1993-12-14 Novo Nordisk A/S Method and apparatus for determination of a constituent in a fluid
US5312762A (en) * 1989-03-13 1994-05-17 Guiseppi Elie Anthony Method of measuring an analyte by measuring electrical resistance of a polymer film reacting with the analyte
GB8927377D0 (en) * 1989-12-04 1990-01-31 Univ Edinburgh Improvements in and relating to amperometric assays
ATE124990T1 (de) * 1989-12-15 1995-07-15 Boehringer Mannheim Corp Redox-vermittlungs-reagenz und biosensor.
US4999582A (en) * 1989-12-15 1991-03-12 Boehringer Mannheim Corp. Biosensor electrode excitation circuit
US5508171A (en) * 1989-12-15 1996-04-16 Boehringer Mannheim Corporation Assay method with enzyme electrode system
US5243516A (en) * 1989-12-15 1993-09-07 Boehringer Mannheim Corporation Biosensing instrument and method
US4999632A (en) * 1989-12-15 1991-03-12 Boehringer Mannheim Corporation Analog to digital conversion with noise reduction
JPH0820412B2 (ja) 1990-07-20 1996-03-04 松下電器産業株式会社 使い捨てセンサを用いた定量分析方法、及び装置
US5232668A (en) * 1991-02-27 1993-08-03 Boehringer Mannheim Corporation Test strip holding and reading mechanism for a meter
US5246858A (en) * 1991-02-27 1993-09-21 Boehringer Mannheim Corporation Apparatus and method for analyzing a body fluid
WO1992015859A1 (en) * 1991-02-27 1992-09-17 Boehringer Mannheim Corporation Apparatus and method for analyzing body fluids
JP3251583B2 (ja) * 1991-02-27 2002-01-28 ロシュ ダイアグノスティックス コーポレーション マイクロコンピュータ制御の器械と通信する方法
US5264103A (en) * 1991-10-18 1993-11-23 Matsushita Electric Industrial Co., Ltd. Biosensor and a method for measuring a concentration of a substrate in a sample
JPH05297039A (ja) * 1992-04-10 1993-11-12 M Jones Sado コンピュータによるキャパシタンス変化の検知方法及び装置
US5387327A (en) * 1992-10-19 1995-02-07 Duquesne University Of The Holy Ghost Implantable non-enzymatic electrochemical glucose sensor
US5371687A (en) * 1992-11-20 1994-12-06 Boehringer Mannheim Corporation Glucose test data acquisition and management system
FR2701117B1 (fr) * 1993-02-04 1995-03-10 Asulab Sa Système de mesures électrochimiques à capteur multizones, et son application au dosage du glucose.
US5385846A (en) * 1993-06-03 1995-01-31 Boehringer Mannheim Corporation Biosensor and method for hematocrit determination
US5366609A (en) * 1993-06-08 1994-11-22 Boehringer Mannheim Corporation Biosensing meter with pluggable memory key
US5352351A (en) * 1993-06-08 1994-10-04 Boehringer Mannheim Corporation Biosensing meter with fail/safe procedures to prevent erroneous indications
DE9422380U1 (de) * 1993-06-08 2000-12-14 Roche Diagnostics Corp., Indianapolis, Ind. Biosensor-Meßgerät mit Fehlerschutzprozeduren zur Vermeidung fehlerhafter Anzeigen
US5508203A (en) * 1993-08-06 1996-04-16 Fuller; Milton E. Apparatus and method for radio frequency spectroscopy using spectral analysis
JP3322726B2 (ja) * 1993-08-17 2002-09-09 長野計器株式会社 静電容量検出回路
JPH09502119A (ja) * 1993-08-31 1997-03-04 ベーリンガー・マンハイム・コーポレーション 医療装置用電源の監視制御装置
JPH09502268A (ja) * 1993-08-31 1997-03-04 ベーリンガー・マンハイム・コーポレーション 医療装置用アナログヒータ制御装置
US5841023A (en) * 1993-08-31 1998-11-24 Boehringer Mannheim Corporation Magnet for medical instrument
US5522255A (en) * 1993-08-31 1996-06-04 Boehringer Mannheim Corporation Fluid dose, flow and coagulation sensor for medical instrument
US6153069A (en) * 1995-02-09 2000-11-28 Tall Oak Ventures Apparatus for amperometric Diagnostic analysis
AUPN661995A0 (en) * 1995-11-16 1995-12-07 Memtec America Corporation Electrochemical cell 2
ATE227844T1 (de) 1997-02-06 2002-11-15 Therasense Inc Kleinvolumiger sensor zur in-vitro bestimmung
US6121050A (en) * 1997-08-29 2000-09-19 Han; Chi-Neng Arthur Analyte detection systems
CA2547299C (en) 1997-12-04 2009-03-03 Roche Diagnostics Corporation Instrument and method
US5997817A (en) * 1997-12-05 1999-12-07 Roche Diagnostics Corporation Electrochemical biosensor test strip
EP1042667B1 (en) * 1997-12-22 2009-06-17 Roche Diagnostics Operations, Inc. Meter
JP3848993B2 (ja) * 1998-01-06 2006-11-22 アークレイ株式会社 共存物質の存在下における成分量の測定方法及び測定装置
JP4256588B2 (ja) * 1998-05-20 2009-04-22 アークレイ株式会社 統計的手法を用いた電気化学的測定方法および測定装置
US6475372B1 (en) * 2000-02-02 2002-11-05 Lifescan, Inc. Electrochemical methods and devices for use in the determination of hematocrit corrected analyte concentrations
US6287451B1 (en) * 1999-06-02 2001-09-11 Handani Winarta Disposable sensor and method of making
US7018843B2 (en) * 2001-11-07 2006-03-28 Roche Diagnostics Operations, Inc. Instrument

Also Published As

Publication number Publication date
US7927882B2 (en) 2011-04-19
JP2005509161A (ja) 2005-04-07
US20080293082A1 (en) 2008-11-27
CA2465800A1 (en) 2003-05-15
WO2003040728A2 (en) 2003-05-15
EP1456666A2 (en) 2004-09-15
JP4180518B2 (ja) 2008-11-12
JP4722900B2 (ja) 2011-07-13
US20030096420A1 (en) 2003-05-22
US7018843B2 (en) 2006-03-28
JP2008046141A (ja) 2008-02-28
US7923258B2 (en) 2011-04-12
US20060035384A1 (en) 2006-02-16
EP1456666B1 (en) 2012-07-18
WO2003040728A3 (en) 2004-02-19

Similar Documents

Publication Publication Date Title
CA2465800C (en) Instrument
JP3848993B2 (ja) 共存物質の存在下における成分量の測定方法及び測定装置
CA2566495C (en) Performing hematocrit adjustment in glucose assays
US20070264721A1 (en) System and method for analyte measurement using a nonlinear sample response
EP1042667B1 (en) Meter
CA2798938C (en) Slope-based compensation including secondary output signals
US11268925B2 (en) Intertwined electrical input signals
JP2005518527A (ja) 電気化学的特性についてのアッセイのための方法および装置
JP2015155919A (ja) 信号調整を持つバイオセンサシステム
JP2013528289A5 (enExample)
CN106908501B (zh) 分析物浓度测定的系统误差补偿
EP3213059B1 (en) Method for determining diffusion
CA2481622C (en) An apparatus and method for determining the concentration of a component in a fluid
HK1242768B (en) Method for determining diffusion
HK1242768A1 (en) Method for determining diffusion
HK1142399A (en) System and method for analyte measurement using a nonlinear sample response

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20221107