CA2457362C - Anticorps monoclonaux humains neutralisant le virus de la rage et les procedes de fabrication et d'utilisation desdits anticorps - Google Patents
Anticorps monoclonaux humains neutralisant le virus de la rage et les procedes de fabrication et d'utilisation desdits anticorps Download PDFInfo
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- CA2457362C CA2457362C CA2457362A CA2457362A CA2457362C CA 2457362 C CA2457362 C CA 2457362C CA 2457362 A CA2457362 A CA 2457362A CA 2457362 A CA2457362 A CA 2457362A CA 2457362 C CA2457362 C CA 2457362C
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La présente invention concerne des anticorps de recombinaison. Cette invention concerne aussi l'acide nucléique et les séquences d'amino acides codées de la chaîne lourde et légère d'immunoglobulines d'anticorps monoclonaux humains neutralisant le virus de la rage et l'utilisation de ceux-ci.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31402301P | 2001-08-21 | 2001-08-21 | |
| US60/314,023 | 2001-08-21 | ||
| PCT/US2002/026584 WO2003016501A2 (fr) | 2001-08-21 | 2002-08-21 | Anticorps de recombinaison, compositions et techniques de fabrication et d'utilisation de ces anticorps |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2457362A1 CA2457362A1 (fr) | 2003-02-27 |
| CA2457362C true CA2457362C (fr) | 2012-01-17 |
Family
ID=23218208
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2457362A Expired - Fee Related CA2457362C (fr) | 2001-08-21 | 2002-08-21 | Anticorps monoclonaux humains neutralisant le virus de la rage et les procedes de fabrication et d'utilisation desdits anticorps |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1530579B1 (fr) |
| CN (1) | CN1636019B (fr) |
| AT (1) | ATE557040T1 (fr) |
| AU (1) | AU2002332600B2 (fr) |
| CA (1) | CA2457362C (fr) |
| HK (1) | HK1071898A1 (fr) |
| MX (1) | MXPA04001609A (fr) |
| NZ (1) | NZ531291A (fr) |
| RU (1) | RU2292353C2 (fr) |
| WO (1) | WO2003016501A2 (fr) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040013672A1 (en) * | 2000-05-16 | 2004-01-22 | Thomas Jefferson University | Recombinant antibodies, and compositions and methods for making and using the same |
| CN101537180B (zh) | 2002-07-18 | 2016-02-10 | 莫鲁斯有限公司 | 抗体混合物的重组生产 |
| USRE47770E1 (en) | 2002-07-18 | 2019-12-17 | Merus N.V. | Recombinant production of mixtures of antibodies |
| ES2408582T3 (es) * | 2003-05-30 | 2013-06-21 | Merus B.V. | Biblioteca de Fab para la preparación de una mezcla de anticuerpos |
| US20100069614A1 (en) | 2008-06-27 | 2010-03-18 | Merus B.V. | Antibody producing non-human mammals |
| WO2005000225A2 (fr) * | 2003-06-02 | 2005-01-06 | University Of Oxford | Production d'anticorps contre la rage dans des plantes |
| DK1737971T3 (da) | 2004-01-20 | 2017-11-13 | Merus Nv | Blandinger af bindingsproteiner |
| RS53269B (en) * | 2004-05-27 | 2014-08-29 | Crucell Holland B.V. | BINDING MOLECULES WHICH MAY NEUTRALIZE FRAGILE VIRUS AND USE |
| EP1941043B1 (fr) * | 2005-10-21 | 2011-04-13 | F. Hoffmann-La Roche AG | Procede d'expression par recombinaison d'un polypeptide |
| CN101100663B (zh) * | 2006-07-05 | 2011-08-24 | 华北制药集团新药研究开发有限责任公司 | 重组人抗狂犬病毒单克隆抗体的制备方法 |
| KR101522036B1 (ko) | 2006-12-05 | 2015-05-20 | 크루셀 홀란드 비.브이. | 액체 항-광견병 항체 조성물 |
| CN101337990B (zh) * | 2008-06-25 | 2011-04-06 | 中国人民解放军军事医学科学院微生物流行病研究所 | 人源抗狂犬病毒中和性抗体及其制备方法与用途 |
| CN101696242B (zh) * | 2009-10-26 | 2011-12-28 | 中国人民解放军南京军区军事医学研究所 | 人源抗狂犬病毒中和抗体Fab及其制备方法和应用 |
| PT2838918T (pt) | 2012-04-20 | 2019-08-23 | Merus Nv | Métodos e meios para a produção de moléculas heterrodiméricas do tipo ig |
| RU2682677C2 (ru) * | 2017-09-07 | 2019-03-20 | Федеральное бюджетное учреждение науки "Екатеринбургский научно-исследовательский институт вирусных инфекций" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФБУН "ЕНИИВИ" Роспотребнадзора) | Способ постэкспозиционной профилактики клещевого энцефалита |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1282703B1 (fr) * | 2000-05-16 | 2008-10-15 | Thomas Jefferson University | Anticorps monoclonaux humains de neutralisation du virus de la rage, acides nucleiques et procedes associes |
-
2002
- 2002-08-21 MX MXPA04001609A patent/MXPA04001609A/es active IP Right Grant
- 2002-08-21 AT AT02794932T patent/ATE557040T1/de active
- 2002-08-21 NZ NZ531291A patent/NZ531291A/en not_active IP Right Cessation
- 2002-08-21 CA CA2457362A patent/CA2457362C/fr not_active Expired - Fee Related
- 2002-08-21 EP EP02794932A patent/EP1530579B1/fr not_active Expired - Lifetime
- 2002-08-21 AU AU2002332600A patent/AU2002332600B2/en not_active Ceased
- 2002-08-21 WO PCT/US2002/026584 patent/WO2003016501A2/fr active IP Right Grant
- 2002-08-21 CN CN028164334A patent/CN1636019B/zh not_active Expired - Lifetime
- 2002-08-21 RU RU2004108115/13A patent/RU2292353C2/ru not_active IP Right Cessation
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- 2005-06-01 HK HK05104601.8A patent/HK1071898A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1530579A2 (fr) | 2005-05-18 |
| AU2002332600B2 (en) | 2007-03-22 |
| ATE557040T1 (de) | 2012-05-15 |
| EP1530579B1 (fr) | 2012-05-09 |
| RU2292353C2 (ru) | 2007-01-27 |
| CN1636019B (zh) | 2010-06-16 |
| EP1530579A4 (fr) | 2006-02-08 |
| WO2003016501A3 (fr) | 2005-03-24 |
| WO2003016501A2 (fr) | 2003-02-27 |
| NZ531291A (en) | 2006-02-24 |
| CA2457362A1 (fr) | 2003-02-27 |
| RU2004108115A (ru) | 2005-09-27 |
| CN1636019A (zh) | 2005-07-06 |
| MXPA04001609A (es) | 2005-03-07 |
| HK1071898A1 (en) | 2005-08-05 |
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