ATE557040T1 - Rekombinante antikörper sowie zusammensetzungen und verfahren zu deren herstellung und verwendung - Google Patents
Rekombinante antikörper sowie zusammensetzungen und verfahren zu deren herstellung und verwendungInfo
- Publication number
- ATE557040T1 ATE557040T1 AT02794932T AT02794932T ATE557040T1 AT E557040 T1 ATE557040 T1 AT E557040T1 AT 02794932 T AT02794932 T AT 02794932T AT 02794932 T AT02794932 T AT 02794932T AT E557040 T1 ATE557040 T1 AT E557040T1
- Authority
- AT
- Austria
- Prior art keywords
- recombinant antibodies
- compositions
- production
- methods
- antibodies
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- 102000006496 Immunoglobulin Heavy Chains Human genes 0.000 abstract 1
- 108010019476 Immunoglobulin Heavy Chains Proteins 0.000 abstract 1
- 102000013463 Immunoglobulin Light Chains Human genes 0.000 abstract 1
- 108010065825 Immunoglobulin Light Chains Proteins 0.000 abstract 1
- 241000711798 Rabies lyssavirus Species 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31402301P | 2001-08-21 | 2001-08-21 | |
| PCT/US2002/026584 WO2003016501A2 (en) | 2001-08-21 | 2002-08-21 | Recombinant antibodies, and compositions and methods for making and using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE557040T1 true ATE557040T1 (de) | 2012-05-15 |
Family
ID=23218208
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02794932T ATE557040T1 (de) | 2001-08-21 | 2002-08-21 | Rekombinante antikörper sowie zusammensetzungen und verfahren zu deren herstellung und verwendung |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1530579B1 (de) |
| CN (1) | CN1636019B (de) |
| AT (1) | ATE557040T1 (de) |
| AU (1) | AU2002332600B2 (de) |
| CA (1) | CA2457362C (de) |
| HK (1) | HK1071898A1 (de) |
| MX (1) | MXPA04001609A (de) |
| NZ (1) | NZ531291A (de) |
| RU (1) | RU2292353C2 (de) |
| WO (1) | WO2003016501A2 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040013672A1 (en) * | 2000-05-16 | 2004-01-22 | Thomas Jefferson University | Recombinant antibodies, and compositions and methods for making and using the same |
| USRE47770E1 (en) | 2002-07-18 | 2019-12-17 | Merus N.V. | Recombinant production of mixtures of antibodies |
| CN101537180B (zh) | 2002-07-18 | 2016-02-10 | 莫鲁斯有限公司 | 抗体混合物的重组生产 |
| AU2004242614B2 (en) * | 2003-05-30 | 2011-09-22 | Merus N.V. | Fab library for the preparation of anti vegf and anti rabies virus fabs |
| US20100069614A1 (en) | 2008-06-27 | 2010-03-18 | Merus B.V. | Antibody producing non-human mammals |
| US20060134099A1 (en) * | 2003-06-02 | 2006-06-22 | Biotechnology Foundation, Inc. | Production of rabies antibodies in plants |
| NZ548828A (en) | 2004-01-20 | 2009-07-31 | Merus B V | Mixtures of binding proteins |
| EP2314621B1 (de) | 2004-05-27 | 2014-03-05 | Crucell Holland B.V. | Bindungsmoleküle, die zur Neutralisierung des Tollwutvirus fähig sind, sowie deren Verwendungen |
| JP4860702B2 (ja) | 2005-10-21 | 2012-01-25 | エフ．ホフマン−ラ ロシュ アーゲー | ポリペプチドのリコンビナント発現のための方法 |
| CN101100663B (zh) * | 2006-07-05 | 2011-08-24 | 华北制药集团新药研究开发有限责任公司 | 重组人抗狂犬病毒单克隆抗体的制备方法 |
| WO2008068246A1 (en) | 2006-12-05 | 2008-06-12 | Crucell Holland B.V. | Liquid anti-rabies antibody formulations |
| CN101337990B (zh) * | 2008-06-25 | 2011-04-06 | 中国人民解放军军事医学科学院微生物流行病研究所 | 人源抗狂犬病毒中和性抗体及其制备方法与用途 |
| CN101696242B (zh) * | 2009-10-26 | 2011-12-28 | 中国人民解放军南京军区军事医学研究所 | 人源抗狂犬病毒中和抗体Fab及其制备方法和应用 |
| EP3594232A1 (de) | 2012-04-20 | 2020-01-15 | Merus N.V. | Verfahren und mittel zur herstellung von ig-like-molekülen |
| RU2682677C2 (ru) * | 2017-09-07 | 2019-03-20 | Федеральное бюджетное учреждение науки "Екатеринбургский научно-исследовательский институт вирусных инфекций" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФБУН "ЕНИИВИ" Роспотребнадзора) | Способ постэкспозиционной профилактики клещевого энцефалита |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60136174D1 (de) * | 2000-05-16 | 2008-11-27 | Univ Jefferson | Rabiesvirus-spezifische neutralisierende humane monoklonale antikörper und nukleinsäure und relatierte verfahren |
-
2002
- 2002-08-21 MX MXPA04001609A patent/MXPA04001609A/es active IP Right Grant
- 2002-08-21 EP EP02794932A patent/EP1530579B1/de not_active Expired - Lifetime
- 2002-08-21 AU AU2002332600A patent/AU2002332600B2/en not_active Ceased
- 2002-08-21 RU RU2004108115/13A patent/RU2292353C2/ru not_active IP Right Cessation
- 2002-08-21 CN CN028164334A patent/CN1636019B/zh not_active Expired - Lifetime
- 2002-08-21 CA CA2457362A patent/CA2457362C/en not_active Expired - Fee Related
- 2002-08-21 AT AT02794932T patent/ATE557040T1/de active
- 2002-08-21 WO PCT/US2002/026584 patent/WO2003016501A2/en active IP Right Grant
- 2002-08-21 NZ NZ531291A patent/NZ531291A/en not_active IP Right Cessation
-
2005
- 2005-06-01 HK HK05104601.8A patent/HK1071898A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1636019A (zh) | 2005-07-06 |
| NZ531291A (en) | 2006-02-24 |
| RU2292353C2 (ru) | 2007-01-27 |
| EP1530579B1 (de) | 2012-05-09 |
| CA2457362C (en) | 2012-01-17 |
| EP1530579A4 (de) | 2006-02-08 |
| HK1071898A1 (en) | 2005-08-05 |
| RU2004108115A (ru) | 2005-09-27 |
| CA2457362A1 (en) | 2003-02-27 |
| CN1636019B (zh) | 2010-06-16 |
| AU2002332600B2 (en) | 2007-03-22 |
| WO2003016501A3 (en) | 2005-03-24 |
| WO2003016501A2 (en) | 2003-02-27 |
| MXPA04001609A (es) | 2005-03-07 |
| EP1530579A2 (de) | 2005-05-18 |
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