CA2447222C - Polynucleotide sequencing method - Google Patents

Polynucleotide sequencing method Download PDF

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Publication number
CA2447222C
CA2447222C CA2447222A CA2447222A CA2447222C CA 2447222 C CA2447222 C CA 2447222C CA 2447222 A CA2447222 A CA 2447222A CA 2447222 A CA2447222 A CA 2447222A CA 2447222 C CA2447222 C CA 2447222C
Authority
CA
Canada
Prior art keywords
enzyme
polynucleotide
immobilised
molecule
solid support
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2447222A
Other languages
English (en)
French (fr)
Other versions
CA2447222A1 (en
Inventor
Daniel Henry Densham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gen Probe Inc
Original Assignee
Gen Probe Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Probe Inc filed Critical Gen Probe Inc
Publication of CA2447222A1 publication Critical patent/CA2447222A1/en
Application granted granted Critical
Publication of CA2447222C publication Critical patent/CA2447222C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
CA2447222A 2001-05-18 2002-05-20 Polynucleotide sequencing method Expired - Lifetime CA2447222C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0112238.1 2001-05-18
GBGB0112238.1A GB0112238D0 (en) 2001-05-18 2001-05-18 Sequencing method
PCT/GB2002/002345 WO2002095070A2 (en) 2001-05-18 2002-05-20 Polynucleotide sequencing method

Publications (2)

Publication Number Publication Date
CA2447222A1 CA2447222A1 (en) 2002-11-28
CA2447222C true CA2447222C (en) 2012-09-18

Family

ID=9914926

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2447222A Expired - Lifetime CA2447222C (en) 2001-05-18 2002-05-20 Polynucleotide sequencing method

Country Status (21)

Country Link
US (3) US9476094B2 (zh)
EP (1) EP1389241B1 (zh)
JP (2) JP4094961B2 (zh)
KR (1) KR20030094412A (zh)
CN (1) CN1537172B (zh)
AT (1) ATE383442T1 (zh)
AU (1) AU2002257933B2 (zh)
BR (1) BR0209841A (zh)
CA (1) CA2447222C (zh)
DE (1) DE60224524T2 (zh)
DK (1) DK1389241T3 (zh)
ES (1) ES2299569T3 (zh)
GB (1) GB0112238D0 (zh)
HK (1) HK1061047A1 (zh)
IL (1) IL158743A0 (zh)
IS (1) IS7039A (zh)
MX (1) MXPA03010411A (zh)
NZ (1) NZ529349A (zh)
PT (1) PT1389241E (zh)
RU (1) RU2291197C2 (zh)
WO (1) WO2002095070A2 (zh)

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US7998672B2 (en) 2006-05-30 2011-08-16 The University Of Utah Research Foundation Simultaneous amplification and detection of ribonucleic acid be an optical method using surface plasmon resonance
US8697138B2 (en) 2007-03-28 2014-04-15 Aker Biomarine As Methods of using krill oil to treat risk factors for cardiovascular, metabolic, and inflammatory disorders
ATE548643T1 (de) * 2007-03-30 2012-03-15 Pacific Biosciences California System und verfahren zur verstärkung von fluoreszenzsignalen
JP5222599B2 (ja) * 2007-07-20 2013-06-26 株式会社日立ハイテクノロジーズ 核酸分析デバイス及びそれを用いた核酸分析装置
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JP5175584B2 (ja) * 2008-03-13 2013-04-03 地方独立行政法人 東京都立産業技術研究センター 局所表面プラズモン共鳴イメージング装置
MX2010010600A (es) 2008-03-28 2011-03-30 Pacific Biosciences California Inc Composiciones y metodos para secuenciacion de acidos nucleicos.
US9182406B2 (en) 2008-08-04 2015-11-10 Biodesy, Inc. Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability
JP5854350B2 (ja) * 2010-12-08 2016-02-09 公立大学法人大阪府立大学 金属ナノ粒子集積構造体を利用した圧力検出装置、温度検出装置、圧力検出方法、および温度検出方法
GB2503604B (en) 2011-03-21 2020-04-22 Biodesy Llc Classification of kinase inhibitors using second harmonic optical techniques
US9279154B2 (en) 2011-12-21 2016-03-08 Illumina, Inc. Apparatus and methods for kinetic analysis and determination of nucleic acid sequences
US9395358B2 (en) 2012-02-05 2016-07-19 Biodesy, Inc. Methods for detecting allosteric modulators of protein
US20130288271A1 (en) 2012-04-25 2013-10-31 Biodesy, Llc Methods for detecting allosteric modulators of protein
US9938560B2 (en) 2012-02-05 2018-04-10 Biodesy, Inc. Methods for identifying modulators of Ras using nonlinear techniques
WO2014182630A1 (en) 2013-05-06 2014-11-13 Pacific Biosciences Of California , Inc. Real-time electronic sequencing
US9989534B2 (en) 2014-06-30 2018-06-05 Biodesy, Inc. Systems and methods for high throughput analysis of conformation in biological entities
WO2016106286A1 (en) 2014-12-23 2016-06-30 Biodesy, Inc. Attachment of proteins to interfaces for use in nonlinear optical detection
US10672502B2 (en) 2015-04-02 2020-06-02 Biodesy, Inc. Methods for determining protein structure using a surface-selective nonlinear optical technique
US10077470B2 (en) 2015-07-21 2018-09-18 Omniome, Inc. Nucleic acid sequencing methods and systems
CN107849605B (zh) * 2015-07-21 2021-08-20 欧姆尼欧美公司 核酸测序方法和系统
WO2017196891A1 (en) 2016-05-09 2017-11-16 Biodesy, Inc. Methods and devices for detection of peripheral membrane protein interactions using nonlinear optical techniques
DK3566158T3 (da) 2017-01-06 2022-07-18 Illumina Inc Faseinddelingskorrektion
CA3046015A1 (en) * 2017-03-07 2018-09-13 Illumina, Inc. Single light source, two-optical channel sequencing
CN107064106B (zh) * 2017-04-11 2019-07-05 北京航空航天大学 一种二维表面等离子体最佳激发角位置的高精度识别方法
CN110511991A (zh) * 2019-09-11 2019-11-29 胡志刚 大规模dna芯片技术
GB2593729B (en) 2020-03-31 2022-05-11 Perkins Engines Co Ltd Spacer for use in an air intake system of an internal combustion chamber

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Also Published As

Publication number Publication date
NZ529349A (en) 2006-10-27
CN1537172A (zh) 2004-10-13
EP1389241A2 (en) 2004-02-18
EP1389241B1 (en) 2008-01-09
AU2002257933B2 (en) 2006-08-10
PT1389241E (pt) 2008-04-17
WO2002095070A2 (en) 2002-11-28
CA2447222A1 (en) 2002-11-28
GB0112238D0 (en) 2001-07-11
JP4094961B2 (ja) 2008-06-04
WO2002095070A3 (en) 2003-09-18
RU2003136429A (ru) 2005-05-27
JP4907498B2 (ja) 2012-03-28
DE60224524D1 (de) 2008-02-21
ES2299569T3 (es) 2008-06-01
DE60224524T2 (de) 2009-01-08
JP2004535800A (ja) 2004-12-02
US20090029383A1 (en) 2009-01-29
RU2291197C2 (ru) 2007-01-10
DK1389241T3 (da) 2008-05-26
US9476094B2 (en) 2016-10-25
US20170022556A1 (en) 2017-01-26
US20040241678A1 (en) 2004-12-02
JP2008104463A (ja) 2008-05-08
IS7039A (is) 2003-11-17
BR0209841A (pt) 2006-02-07
ATE383442T1 (de) 2008-01-15
MXPA03010411A (es) 2004-06-25
CN1537172B (zh) 2013-02-20
HK1061047A1 (en) 2004-09-03
IL158743A0 (en) 2004-05-12
KR20030094412A (ko) 2003-12-11

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