ATE548643T1 - System und verfahren zur verstärkung von fluoreszenzsignalen - Google Patents

System und verfahren zur verstärkung von fluoreszenzsignalen

Info

Publication number
ATE548643T1
ATE548643T1 AT08742395T AT08742395T ATE548643T1 AT E548643 T1 ATE548643 T1 AT E548643T1 AT 08742395 T AT08742395 T AT 08742395T AT 08742395 T AT08742395 T AT 08742395T AT E548643 T1 ATE548643 T1 AT E548643T1
Authority
AT
Austria
Prior art keywords
fluorescent signals
illumination light
metal particle
amplifying fluorescent
reflectance
Prior art date
Application number
AT08742395T
Other languages
English (en)
Inventor
Jonas Korlach
Kevan Samiee
Stephen Turner
Jake Freudenthal
Original Assignee
Pacific Biosciences California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pacific Biosciences California filed Critical Pacific Biosciences California
Application granted granted Critical
Publication of ATE548643T1 publication Critical patent/ATE548643T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Luminescent Compositions (AREA)
AT08742395T 2007-03-30 2008-03-27 System und verfahren zur verstärkung von fluoreszenzsignalen ATE548643T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92116707P 2007-03-30 2007-03-30
PCT/US2008/004148 WO2008121374A2 (en) 2007-03-30 2008-03-27 Systems and methods for enhancing fluorescent signals

Publications (1)

Publication Number Publication Date
ATE548643T1 true ATE548643T1 (de) 2012-03-15

Family

ID=39795079

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08742395T ATE548643T1 (de) 2007-03-30 2008-03-27 System und verfahren zur verstärkung von fluoreszenzsignalen

Country Status (4)

Country Link
US (1) US20080241866A1 (de)
EP (1) EP2134871B1 (de)
AT (1) ATE548643T1 (de)
WO (1) WO2008121374A2 (de)

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EP3460458B1 (de) 2010-02-19 2021-08-11 Pacific Biosciences of California, Inc. Verfahren zur nukleinsäuresequenzierung
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EP2564191B1 (de) 2010-04-28 2017-11-01 Pacific Biosciences Of California, Inc. Nanoskalige öffnungen mit funktionsinseln
JP2013525811A (ja) * 2010-05-03 2013-06-20 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア オンチップの広視野のレンズフリー蛍光画像化
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US8735175B2 (en) 2011-03-18 2014-05-27 Chris D. Geddes Multicolor microwave-accelerated metal-enhanced fluorescence (M-MAMEF)
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EP3471402B1 (de) 2014-08-08 2023-05-31 Quantum-Si Incorporated Integrierte vorrichtung zur temporären gruppierung von empfangenen photonen
US10174363B2 (en) 2015-05-20 2019-01-08 Quantum-Si Incorporated Methods for nucleic acid sequencing
CA2957543A1 (en) 2014-08-08 2016-02-11 Quantum-Si Incorporated Optical system and assay chip for probing, detecting and analyzing molecules
EP4421188A3 (de) 2014-08-08 2024-10-23 Quantum-Si Incorporated Integrierte vorrichtung mit externer lichtquelle zur sondierung, detektion und analyse von molekülen
EP2997883A1 (de) * 2014-09-17 2016-03-23 Universität Stuttgart Verfahren und Anordnung zur optischen Absorptionsmessung
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CN105352922B (zh) * 2016-01-04 2017-12-19 广东省生态环境与土壤研究所 一种y形dna组装结合信号扩增用于汞离子的检测方法及检测试剂盒
KR20180111999A (ko) 2016-02-17 2018-10-11 테서렉트 헬스, 인코포레이티드 수명 촬상 및 검출 응용을 위한 센서 및 디바이스
US10876969B2 (en) * 2016-08-10 2020-12-29 Atila Biosystems Incorporated Apparatus for detecting fluorescent signals emitted by samples
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Also Published As

Publication number Publication date
WO2008121374A2 (en) 2008-10-09
EP2134871B1 (de) 2012-03-07
WO2008121374A4 (en) 2009-01-15
EP2134871A2 (de) 2009-12-23
EP2134871A4 (de) 2010-05-26
US20080241866A1 (en) 2008-10-02
WO2008121374A3 (en) 2008-12-04

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