CA2442635A1 - Gastrokines and derived peptides including inhibitors - Google Patents

Gastrokines and derived peptides including inhibitors Download PDF

Info

Publication number
CA2442635A1
CA2442635A1 CA002442635A CA2442635A CA2442635A1 CA 2442635 A1 CA2442635 A1 CA 2442635A1 CA 002442635 A CA002442635 A CA 002442635A CA 2442635 A CA2442635 A CA 2442635A CA 2442635 A1 CA2442635 A1 CA 2442635A1
Authority
CA
Canada
Prior art keywords
protein
peptide
sequence
amino acid
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002442635A
Other languages
English (en)
French (fr)
Inventor
Terence E. Martin
F. Gary Toback
C. Thomas Powell
Kan Agarwal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Chicago
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25234151&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2442635(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CA2442635A1 publication Critical patent/CA2442635A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002442635A 2001-03-29 2002-03-29 Gastrokines and derived peptides including inhibitors Abandoned CA2442635A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/821,726 2001-03-29
US09/821,726 US6734289B2 (en) 2001-03-29 2001-03-29 Gastrokines and derived peptides including inhibitors
PCT/US2002/010148 WO2002092758A2 (en) 2001-03-29 2002-03-29 Gastrokines and derived peptides including inhibitors

Publications (1)

Publication Number Publication Date
CA2442635A1 true CA2442635A1 (en) 2002-11-21

Family

ID=25234151

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002442635A Abandoned CA2442635A1 (en) 2001-03-29 2002-03-29 Gastrokines and derived peptides including inhibitors
CA2442684A Expired - Fee Related CA2442684C (en) 2001-03-29 2002-03-29 Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2442684A Expired - Fee Related CA2442684C (en) 2001-03-29 2002-03-29 Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors

Country Status (10)

Country Link
US (4) US6734289B2 (OSRAM)
EP (2) EP1423409A4 (OSRAM)
JP (3) JP4281947B2 (OSRAM)
AT (1) ATE446510T1 (OSRAM)
AU (2) AU2002303199B2 (OSRAM)
CA (2) CA2442635A1 (OSRAM)
DE (1) DE60234103D1 (OSRAM)
ES (1) ES2332882T3 (OSRAM)
MX (2) MXPA03008855A (OSRAM)
WO (2) WO2002078640A2 (OSRAM)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7629317B2 (en) * 2001-03-29 2009-12-08 The University Of Chicago Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors
US6734289B2 (en) * 2001-03-29 2004-05-11 The University Of Chicago Gastrokines and derived peptides including inhibitors
DE102004047968A1 (de) * 2004-10-01 2006-04-06 B.R.A.H.M.S Ag Bestimmung von Gastrokine 1 (GKN1) als Biomarker für Entzündungen und Infektionen
AU2006244080C1 (en) * 2005-05-10 2012-02-02 The University Of Chicago Use of peptides derived from the growth factor AMP-18 for the treatment of mucositis
US8017576B2 (en) * 2005-05-10 2011-09-13 The University Of Chicago Methods and compositions to treat mucositis
CA2643736C (en) * 2005-05-10 2015-06-23 The University Of Chicago Methods and compositions to treat mucositis
KR101423344B1 (ko) * 2006-01-04 2014-07-30 백스터 인터내셔널 인코포레이티드 올리고펩티드-무함유 세포 배양 배지를 이용하여 단백질을 발현시키는 방법
EP2082674A1 (en) 2008-01-22 2009-07-29 Trelleborg Building Systems AB Waterproof sealing profile
US20100331827A1 (en) * 2008-02-18 2010-12-30 Koninklijke Philips Electronics N.V. Administration of drugs to a patient
EP2943211A4 (en) 2012-12-19 2017-01-25 David Boone Uses of a gastrokine protein
JP7438757B2 (ja) * 2017-02-06 2024-02-27 バイオテンプト・ベー・フェー 治療用途のためのヒトｃペプチドとヒトエラスチン受容体との相互作用のペプチドモジュレーター
KR102590757B1 (ko) * 2020-12-11 2023-10-17 가톨릭대학교 산학협력단 GKN1(Gastrokine 1) 특이적 항체 및 이의 용도

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5476922A (en) 1987-06-24 1995-12-19 Arch Development Corporation Methods and compositions for the preparation and use of autocrine growth factors
US5135856A (en) 1987-06-24 1992-08-04 Arch Development Corp. Production of autocrine growth factors
US5102870A (en) 1989-04-14 1992-04-07 Schering Ag Treatment and prevention of oral mucositis with growth factors
JP2938129B2 (ja) 1989-05-02 1999-08-23 武田薬品工業株式会社 虚血性腎疾患の予防・治療剤
US5644026A (en) * 1994-05-03 1997-07-01 La Jolla Cancer Research Foundation Epitaxin, a cell motility factor
JPH08231413A (ja) 1994-12-29 1996-09-10 Mochida Pharmaceut Co Ltd 臓器障害に基づく疾患の予防・治療剤
JP3859710B2 (ja) 1995-04-21 2006-12-20 三菱化学株式会社 虚血性疾患の予防及び／又は治療剤
AU6229098A (en) * 1997-02-21 1998-09-09 Takara Shuzo Co., Ltd. Cancer-associated genes
US20030068623A1 (en) * 1997-06-16 2003-04-10 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
JP2003516709A (ja) * 1997-08-06 2003-05-20 ジェネティックス・インスチチュート・リミテッド・ライアビリティ・カンパニー 分泌蛋白およびそれらをコードするポリヌクレオチド
CA2331386A1 (en) 1998-06-26 2000-01-06 Incyte Pharmaceuticals, Inc. Human signal peptide-containing proteins
ATE322681T1 (de) 1999-01-21 2006-04-15 Metamorphix Inc Inhibitoren für wachstumdifferenzierungsfaktor und ihre anwendungen
AU3774300A (en) * 1999-06-02 2000-12-18 Genentech Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
ES2287020T3 (es) * 1999-06-02 2007-12-16 Genentech, Inc. Procedimiento y composiciones para inhibir el crecimiento de celulas neoplasicas.
US7629317B2 (en) 2001-03-29 2009-12-08 The University Of Chicago Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors
US6734289B2 (en) 2001-03-29 2004-05-11 The University Of Chicago Gastrokines and derived peptides including inhibitors
US8017576B2 (en) 2005-05-10 2011-09-13 The University Of Chicago Methods and compositions to treat mucositis

Also Published As

Publication number Publication date
US7557083B2 (en) 2009-07-07
CA2442684C (en) 2013-11-19
DE60234103D1 (de) 2009-12-03
US20030017548A1 (en) 2003-01-23
US20130086701A1 (en) 2013-04-04
ES2332882T3 (es) 2010-02-15
EP1423409A2 (en) 2004-06-02
WO2002092758A9 (en) 2004-06-24
JP4295516B2 (ja) 2009-07-15
EP1415154B1 (en) 2009-10-21
WO2002092758A2 (en) 2002-11-21
MXPA03008861A (es) 2004-10-15
US8278269B2 (en) 2012-10-02
US6734289B2 (en) 2004-05-11
ATE446510T1 (de) 2009-11-15
AU2002303199B2 (en) 2008-03-13
AU2002258663B2 (en) 2008-02-21
WO2002092758A3 (en) 2004-04-01
JP2007217422A (ja) 2007-08-30
WO2002078640A3 (en) 2004-03-04
CA2442684A1 (en) 2002-10-10
US8791068B2 (en) 2014-07-29
JP2004537284A (ja) 2004-12-16
EP1415154A2 (en) 2004-05-06
US20050054564A1 (en) 2005-03-10
WO2002092758A8 (en) 2003-02-20
WO2002078640A2 (en) 2002-10-10
JP2004532037A (ja) 2004-10-21
MXPA03008855A (es) 2004-12-06
EP1415154A4 (en) 2004-12-22
US20050065328A1 (en) 2005-03-24
JP4281947B2 (ja) 2009-06-17
EP1423409A4 (en) 2005-12-07

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued