CA2391008C - Crystalline mixtures of partial methyl ethers of beta-cyclodextrin and related compounds - Google Patents

Crystalline mixtures of partial methyl ethers of beta-cyclodextrin and related compounds Download PDF

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Publication number
CA2391008C
CA2391008C CA002391008A CA2391008A CA2391008C CA 2391008 C CA2391008 C CA 2391008C CA 002391008 A CA002391008 A CA 002391008A CA 2391008 A CA2391008 A CA 2391008A CA 2391008 C CA2391008 C CA 2391008C
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CA
Canada
Prior art keywords
cyclodextrin
beta
crystalline
ethers
cyclodextrins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002391008A
Other languages
English (en)
French (fr)
Other versions
CA2391008A1 (en
Inventor
Josef Pitha
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roquette Freres SA
Original Assignee
Roquette Freres SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roquette Freres SA filed Critical Roquette Freres SA
Publication of CA2391008A1 publication Critical patent/CA2391008A1/en
Application granted granted Critical
Publication of CA2391008C publication Critical patent/CA2391008C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/16—Cyclodextrin; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CA002391008A 1999-11-12 2000-11-09 Crystalline mixtures of partial methyl ethers of beta-cyclodextrin and related compounds Expired - Lifetime CA2391008C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16494999P 1999-11-12 1999-11-12
US60/164,949 1999-11-12
PCT/US2000/042064 WO2001036490A2 (en) 1999-11-12 2000-11-09 Crystalline mixtures of partial methyl ethers of beta-cyclodextrin and related compounds

Publications (2)

Publication Number Publication Date
CA2391008A1 CA2391008A1 (en) 2001-05-25
CA2391008C true CA2391008C (en) 2009-12-22

Family

ID=22596786

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002391008A Expired - Lifetime CA2391008C (en) 1999-11-12 2000-11-09 Crystalline mixtures of partial methyl ethers of beta-cyclodextrin and related compounds

Country Status (10)

Country Link
US (1) US6602860B1 (de)
EP (1) EP1272531B8 (de)
JP (1) JP2003514925A (de)
CN (1) CN1303107C (de)
AT (1) ATE348116T1 (de)
AU (1) AU3643301A (de)
CA (1) CA2391008C (de)
DE (1) DE60032388T2 (de)
MX (1) MXPA02004743A (de)
WO (1) WO2001036490A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1462512B1 (de) * 2003-03-24 2007-08-01 The Procter & Gamble Company Zusammensetzungen enthaltend Cyclodextrinkomplexe und mindestens ein Waschmitteladditiv
US11020363B2 (en) 2009-05-29 2021-06-01 Cydex Pharmaceuticals, Inc. Injectable nitrogen mustard compositions comprising a cyclodextrin derivative and methods of making and using the same
CN102458114A (zh) 2009-05-29 2012-05-16 锡德克斯药物公司 包含环糊精衍生物的可注射美法仑组合物及其制备和使用方法
FR2953139B1 (fr) * 2009-11-27 2012-04-13 Servier Lab Composition pharmaceutique comprenant un sel de strontium, de la vitamine d et une cyclodextrine
FR3014694B1 (fr) 2013-12-13 2016-11-11 Roquette Freres Compositions a base de methyl-cyclodextrines pour le traitement et/ou la prevention de maladies par augmentation du taux de cholesterol-hdl
FR3042501B1 (fr) 2015-10-16 2017-11-03 Roquette Freres Nouvelles cyclodextrines methylees et leurs procedes de preparation
WO2021180742A1 (en) 2020-03-09 2021-09-16 Virtexx Methyl-cyclodextrin for use in treating enveloped virus infections such as cov-2
FR3115682B1 (fr) 2020-11-05 2023-02-24 Roquette Freres Compositions à base de méthyl-cyclodextrines pour le traitement et/ou la prévention de la stéatose hépatique
CN113529418B (zh) * 2021-06-29 2023-06-09 安徽三宝棉纺针织投资有限公司 利用有机棉制备抗菌防螨襁褓用品的工艺

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0651725B2 (ja) * 1985-02-28 1994-07-06 メルシャン株式会社 部分メチル化シクロデキストリン及びその製造方法
US4933948A (en) * 1989-05-30 1990-06-12 Eastman Kodak Company Dye laser solutions
US5472954A (en) * 1992-07-14 1995-12-05 Cyclops H.F. Cyclodextrin complexation
HU218280B (en) * 1994-04-26 2000-07-28 Cyclodextrin inclusion complexes containing sin-1a which are stable intheir solid state, process for their preparation and pharmaceutical compositions containing the comlexes
DE19505263A1 (de) * 1995-02-16 1996-08-22 Consortium Elektrochem Ind Verfahren zur Reinigung von wasserlöslichen Cyclodextrinderivaten

Also Published As

Publication number Publication date
WO2001036490A2 (en) 2001-05-25
EP1272531A2 (de) 2003-01-08
CA2391008A1 (en) 2001-05-25
DE60032388T2 (de) 2008-01-10
CN1303107C (zh) 2007-03-07
ATE348116T1 (de) 2007-01-15
EP1272531B1 (de) 2006-12-13
EP1272531B8 (de) 2007-02-14
AU3643301A (en) 2001-05-30
US6602860B1 (en) 2003-08-05
CN1620469A (zh) 2005-05-25
WO2001036490A3 (en) 2001-11-08
EP1272531A4 (de) 2003-03-19
DE60032388D1 (de) 2007-01-25
MXPA02004743A (es) 2003-10-14
JP2003514925A (ja) 2003-04-22

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