CA2379605C - Topical suspension formulations containing ciprofloxacin and dexamethasone - Google Patents

Topical suspension formulations containing ciprofloxacin and dexamethasone Download PDF

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Publication number
CA2379605C
CA2379605C CA002379605A CA2379605A CA2379605C CA 2379605 C CA2379605 C CA 2379605C CA 002379605 A CA002379605 A CA 002379605A CA 2379605 A CA2379605 A CA 2379605A CA 2379605 C CA2379605 C CA 2379605C
Authority
CA
Canada
Prior art keywords
composition
dexamethasone
ciprofloxacin
present
tyloxapol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002379605A
Other languages
English (en)
French (fr)
Other versions
CA2379605A1 (en
Inventor
Onkar N. Singh
Haresh G. Bhagat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22557406&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2379605(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of CA2379605A1 publication Critical patent/CA2379605A1/en
Application granted granted Critical
Publication of CA2379605C publication Critical patent/CA2379605C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
CA002379605A 1999-09-24 2000-08-10 Topical suspension formulations containing ciprofloxacin and dexamethasone Expired - Lifetime CA2379605C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15594299P 1999-09-24 1999-09-24
US60/155,942 1999-09-24
PCT/US2000/021961 WO2001022936A1 (en) 1999-09-24 2000-08-10 Topical suspension formulations containing ciprofloxacin and dexamethasone

Publications (2)

Publication Number Publication Date
CA2379605A1 CA2379605A1 (en) 2001-04-05
CA2379605C true CA2379605C (en) 2007-06-26

Family

ID=22557406

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002379605A Expired - Lifetime CA2379605C (en) 1999-09-24 2000-08-10 Topical suspension formulations containing ciprofloxacin and dexamethasone

Country Status (22)

Country Link
US (2) US6284804B1 (und)
EP (1) EP1214056B1 (und)
JP (2) JP2003510263A (und)
KR (1) KR100722502B1 (und)
CN (1) CN1158994C (und)
AR (1) AR025661A1 (und)
AT (1) ATE252887T1 (und)
AU (1) AU776609B2 (und)
BR (1) BR0014203A (und)
CA (1) CA2379605C (und)
DE (1) DE60006262T2 (und)
DK (1) DK1214056T3 (und)
ES (1) ES2207549T3 (und)
HK (1) HK1045653B (und)
MX (1) MXPA02003130A (und)
PL (1) PL201130B1 (und)
PT (1) PT1214056E (und)
SA (1) SA00210418B1 (und)
TR (1) TR200200737T2 (und)
TW (1) TWI228423B (und)
WO (1) WO2001022936A1 (und)
ZA (1) ZA200201904B (und)

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Also Published As

Publication number Publication date
ZA200201904B (en) 2003-05-28
DK1214056T3 (da) 2004-02-09
CA2379605A1 (en) 2001-04-05
JP2003510263A (ja) 2003-03-18
PT1214056E (pt) 2004-02-27
CN1376054A (zh) 2002-10-23
EP1214056A1 (en) 2002-06-19
US6359016B2 (en) 2002-03-19
WO2001022936A8 (en) 2002-01-24
PL201130B1 (pl) 2009-03-31
JP2011032293A (ja) 2011-02-17
CN1158994C (zh) 2004-07-28
KR20020069508A (ko) 2002-09-04
DE60006262D1 (de) 2003-12-04
US20010034339A1 (en) 2001-10-25
AU7057000A (en) 2001-04-30
EP1214056B1 (en) 2003-10-29
ES2207549T3 (es) 2004-06-01
AU776609B2 (en) 2004-09-16
SA00210418B1 (ar) 2006-04-22
TWI228423B (en) 2005-03-01
US6284804B1 (en) 2001-09-04
PL359623A1 (en) 2004-08-23
KR100722502B1 (ko) 2007-05-28
DE60006262T2 (de) 2004-05-13
WO2001022936A1 (en) 2001-04-05
TR200200737T2 (tr) 2002-08-21
AR025661A1 (es) 2002-12-11
BR0014203A (pt) 2002-05-21
MXPA02003130A (es) 2004-04-21
ATE252887T1 (de) 2003-11-15
HK1045653B (zh) 2004-01-30
HK1045653A1 (en) 2002-12-06

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