CA2344444C - Co-crystallization of sugar and n-[n-(3,3-dimethylbutyl)-l-.alpha.-aspartyl]-l-phenylalanine 1-methyl ester - Google Patents

Co-crystallization of sugar and n-[n-(3,3-dimethylbutyl)-l-.alpha.-aspartyl]-l-phenylalanine 1-methyl ester Download PDF

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Publication number
CA2344444C
CA2344444C CA002344444A CA2344444A CA2344444C CA 2344444 C CA2344444 C CA 2344444C CA 002344444 A CA002344444 A CA 002344444A CA 2344444 A CA2344444 A CA 2344444A CA 2344444 C CA2344444 C CA 2344444C
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CA
Canada
Prior art keywords
sugar
sweetener composition
composition according
crystallized
crystallized sweetener
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002344444A
Other languages
English (en)
French (fr)
Other versions
CA2344444A1 (en
Inventor
Jim Fotos
Ihab E. Bishay
Indra Prakash
Kurt Wachholder
Nitin Desai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nutrasweet Co
Original Assignee
Nutrasweet Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nutrasweet Co filed Critical Nutrasweet Co
Publication of CA2344444A1 publication Critical patent/CA2344444A1/en
Application granted granted Critical
Publication of CA2344444C publication Critical patent/CA2344444C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/346Finished or semi-finished products in the form of powders, paste or liquids
    • AHUMAN NECESSITIES
    • A21BAKING; EDIBLE DOUGHS
    • A21DTREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
    • A21D2/00Treatment of flour or dough by adding materials thereto before or during baking
    • A21D2/08Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
    • A21D2/14Organic oxygen compounds
    • A21D2/18Carbohydrates
    • A21D2/181Sugars or sugar alcohols
    • AHUMAN NECESSITIES
    • A21BAKING; EDIBLE DOUGHS
    • A21DTREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
    • A21D2/00Treatment of flour or dough by adding materials thereto before or during baking
    • A21D2/08Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
    • A21D2/24Organic nitrogen compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52Adding ingredients
    • A23L2/60Sweeteners
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • A23L27/31Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A23L27/32Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06104Dipeptides with the first amino acid being acidic
    • C07K5/06113Asp- or Asn-amino acid
    • C07K5/06121Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613Aspartame
    • CCHEMISTRY; METALLURGY
    • C13SUGAR INDUSTRY
    • C13BPRODUCTION OF SUCROSE; APPARATUS SPECIALLY ADAPTED THEREFOR
    • C13B50/00Sugar products, e.g. powdered, lump or liquid sugar; Working-up of sugar
    • C13B50/002Addition of chemicals or other foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G2200/00COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents
    • A23G2200/06COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents containing beet sugar or cane sugar if specifically mentioned or containing other carbohydrates, e.g. starches, gums, alcohol sugar, polysaccharides, dextrin or containing high or low amount of carbohydrate
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G2200/00COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents
    • A23G2200/10COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents containing amino-acids, proteins, e.g. gelatine, peptides, polypeptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Seasonings (AREA)
  • Peptides Or Proteins (AREA)
CA002344444A 1998-09-17 1999-09-16 Co-crystallization of sugar and n-[n-(3,3-dimethylbutyl)-l-.alpha.-aspartyl]-l-phenylalanine 1-methyl ester Expired - Fee Related CA2344444C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/154,568 1998-09-17
US09/154,568 US6214402B1 (en) 1998-09-17 1998-09-17 Co-crystallization of sugar and n-[n-(3,3-dimethylbutyl)-l αaspartyl]-l-phenylalanine 1-methyl ester
PCT/US1999/021476 WO2000015050A1 (en) 1998-09-17 1999-09-16 CO-CRYSTALLIZATION OF SUGAR AND N-[N-(3,3-DIMETHYLBUTYL)-1-α-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER

Publications (2)

Publication Number Publication Date
CA2344444A1 CA2344444A1 (en) 2000-03-23
CA2344444C true CA2344444C (en) 2004-11-16

Family

ID=22551843

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002344444A Expired - Fee Related CA2344444C (en) 1998-09-17 1999-09-16 Co-crystallization of sugar and n-[n-(3,3-dimethylbutyl)-l-.alpha.-aspartyl]-l-phenylalanine 1-methyl ester

Country Status (9)

Country Link
US (1) US6214402B1 (enExample)
EP (1) EP1139794B1 (enExample)
JP (1) JP4678949B2 (enExample)
AT (1) ATE248526T1 (enExample)
AU (1) AU754433B2 (enExample)
CA (1) CA2344444C (enExample)
DE (1) DE69911056T2 (enExample)
ES (1) ES2207289T3 (enExample)
WO (1) WO2000015050A1 (enExample)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6692778B2 (en) 1998-06-05 2004-02-17 Wm. Wrigley Jr. Company Method of controlling release of N-substituted derivatives of aspartame in chewing gum
US6180157B1 (en) * 1999-02-18 2001-01-30 The Nutrasweet Company Process for preparing an N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester agglomerate
US6506434B1 (en) 1999-08-06 2003-01-14 The Nutrasweet Company Process for coating N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester onto a carrier
WO2001010236A1 (en) * 1999-08-11 2001-02-15 The Nutrasweet Company CONFECTIONERY FOOD PRODUCTS SWEETENED WITH N-[N-(3,3-DIMETHYLBUTYL)-1-α-ASPARTYL]-L-PHENYLALANINE METHYL ESTER
CA2415156A1 (en) * 2000-07-18 2002-01-24 The Nutrasweet Company Drying of neotame with co-agents
US7326430B2 (en) * 2000-07-18 2008-02-05 The Nutrasweet Company Method of preparing liquid compositions for delivery of N-[N- (3,3-dimethylbutyl-L-α-aspartyl]-L-phenylalanine 1-methyl ester in food and beverage systems
US20040258589A1 (en) * 2003-06-23 2004-12-23 Golovanoff Gregory W. Method and apparatus for crystal growth
ITFI20040161A1 (it) * 2004-07-23 2004-10-23 Biosphere S P A Composizione dolcificante a basso potere calorico
US20060188628A1 (en) * 2005-02-04 2006-08-24 Coffield Joseph M Blended sugar sweetener
US7648723B2 (en) 2005-10-26 2010-01-19 Kraft Foods Global Brands Llc Production of low calorie, extruded, expanded foods having a high fiber content
US8956677B2 (en) * 2005-11-23 2015-02-17 The Coca-Cola Company High-potency sweetener composition with glucosamine and compositions sweetened therewith
US20070116836A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-Potency Sweetener Composition for Treatment and/or Prevention of Osteoporosis and Compositions Sweetened Therewith
US9144251B2 (en) * 2005-11-23 2015-09-29 The Coca-Cola Company High-potency sweetener composition with mineral and compositions sweetened therewith
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US8993027B2 (en) * 2005-11-23 2015-03-31 The Coca-Cola Company Natural high-potency tabletop sweetener compositions with improved temporal and/or flavor profile, methods for their formulation, and uses
US8956678B2 (en) * 2005-11-23 2015-02-17 The Coca-Cola Company High-potency sweetener composition with preservative and compositions sweetened therewith
US20070116822A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company High-potency sweetener composition with saponin and compositions sweetened therewith
US20070116831A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Dental Composition with High-Potency Sweetener
AP2008004494A0 (en) * 2005-11-23 2008-06-30 Coca Cola Co Synthetic sweetener compositions with improved temporal profile and/or flavour profile, methods for their formulations, ans uses
US20070134391A1 (en) * 2005-11-23 2007-06-14 The Coca-Cola Company High-Potency Sweetener Composition for Treatment and/or Prevention of Autoimmune Disorders and Compositions Sweetened Therewith
US20070116825A1 (en) * 2005-11-23 2007-05-24 The Coca-Cola Company Confection with High-Potency Sweetener
US9232537B2 (en) 2006-02-07 2016-01-05 Qualcomm Incorporated Apparatus and method for fast access in a wireless communication system
US8404297B2 (en) * 2006-06-13 2013-03-26 Ingenio del Cauca S.A.—Incauca S.A. Process for co-crystallizing sucrose and a natural sweetener and the product thereof
US20080003339A1 (en) * 2006-06-30 2008-01-03 Clinton Johnson Seasoning and method for seasoning a food product utilizing small particle sea salt
US20080038411A1 (en) * 2006-06-30 2008-02-14 Michael Jensen Seasoning and method for enhancing and potentiating food flavor
US7923047B2 (en) * 2006-06-30 2011-04-12 Conagra Foods Rdm, Inc. Seasoning and method for seasoning a food product while reducing dietary sodium intake
US20080008790A1 (en) * 2006-06-30 2008-01-10 Michael Jensen Seasoned food, seasoning, and method for seasoning a food product
US20110097449A1 (en) * 2006-06-30 2011-04-28 Conagra Foods Rdm, Inc. Seasoning and method for seasoning a food product while reducing dietary sodium intake
US20080014331A1 (en) * 2006-07-17 2008-01-17 Constantin Badalov Super sweet sugar crystals and syrups for health and method
MX2009003329A (es) * 2006-09-27 2009-07-31 Conagra Foods Rdm Inc Sazonador y metodo para mejorar y potenciar el sabor de un alimento utilizando microencapsulacion.
US9101161B2 (en) * 2006-11-02 2015-08-11 The Coca-Cola Company High-potency sweetener composition with phytoestrogen and compositions sweetened therewith
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
US20080107787A1 (en) * 2006-11-02 2008-05-08 The Coca-Cola Company Anti-Diabetic Composition with High-Potency Sweetener
US20080292775A1 (en) * 2007-05-22 2008-11-27 The Coca-Cola Company Delivery Systems for Natural High-Potency Sweetener Compositions, Methods for Their Formulation, and Uses
JP5548506B2 (ja) * 2009-04-07 2014-07-16 Dsp五協フード&ケミカル株式会社 ネオテームを含有する組成物
US20150344512A1 (en) 2011-12-19 2015-12-03 Purecircle Usa Inc. Methods of purifying steviol glycosides and uses of the same
BR112012023446A8 (pt) * 2010-03-16 2022-09-20 Imp Sugar Company Processo para fabricação de sacarose co-cristalizada-adoçantes naturais de poliol e seus produtos
AU2014271347B2 (en) * 2010-03-16 2016-07-28 United States Sugar Savannah Refinery, Llc Process for the manufacture of cocrystallized sucrose - polyol natural sweeteners and products thereof
US8357417B2 (en) 2010-03-31 2013-01-22 Purecircle Sdn Bhd Low calorie composite sweetener as sugar alternative and methods for producing the same
WO2012164383A1 (en) * 2011-06-03 2012-12-06 Abba Pharma Limited Sweetness enhanced sugars and sugar like products
AR087157A1 (es) 2011-06-20 2014-02-26 Gen Biscuit Galletita saludable
EP3735841A1 (en) 2011-12-19 2020-11-11 PureCircle SDN BHD Methods for purifying steviol glycosides and uses of the same
US20140044852A1 (en) * 2012-08-13 2014-02-13 Mcneil Nutritionals, Llc. Sweetener crystals and method of making
WO2014095674A1 (en) * 2012-12-21 2014-06-26 Firmenich Sa Co-crystallized sweeteners
CN103169059A (zh) * 2013-04-11 2013-06-26 福建科宏生物工程有限公司 一种液体复合高倍甜味剂及其制备方法
BR112017024772A2 (pt) 2015-05-20 2018-07-31 Cargill Inc composição de adoçante e bebida
MX394171B (es) * 2017-03-06 2025-03-24 Athena Pharmaceutiques Sas Una composicion farmaceutica que comprende racecadotrilo y procedimiento para preparar la misma
BR112020006437A2 (pt) 2017-09-28 2020-09-29 Purecircle Usa Inc. métodos de preparação de glicosídeos de esteviol e usos dos mesmos
FR3102041B1 (fr) 2019-10-22 2025-02-14 Aroma Sens Edulcorant pour liquides de cigarette électronique

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4031258A (en) * 1972-03-30 1977-06-21 General Foods Corporation Inorganic salts of dipeptide sweeteners
CA1028197A (en) * 1973-04-02 1978-03-21 Jeffrey H. Berg Concentrated liquid low calorie sweetener
US4362757A (en) 1980-10-22 1982-12-07 Amstar Corporation Crystallized, readily water dispersible sugar product containing heat sensitive, acidic or high invert sugar substances
JPS58155054A (ja) * 1982-03-10 1983-09-14 Ajinomoto Co Inc ジペプチド甘味料含有糖結晶及びその製造法
JPS5963158A (ja) * 1982-10-04 1984-04-10 Ajinomoto Co Inc 顆粒状若しくは結晶状甘味料又は食品の製造法
JPS60114169A (ja) * 1983-11-22 1985-06-20 Showa Sangyo Kk 甘味料の製造方法
JP2540685B2 (ja) * 1991-03-06 1996-10-09 ザ ヌトラスウィート カンパニー カラメルを含む速溶性甘味料
FR2697844B1 (fr) 1992-11-12 1995-01-27 Claude Nofre Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation.
FR2719590B1 (fr) * 1994-05-09 1996-07-26 Claude Nofre Procédé perfectionné de préparation d'un composé dérivé de l'aspartame utile comme agent édulcorant.
US5728862A (en) 1997-01-29 1998-03-17 The Nutrasweet Company Method for preparing and purifying an N-alkylated aspartame derivative
AR014129A1 (es) 1997-12-17 2001-02-07 Nutrasweet Co Bebida que comprende fundamentalmente un ester n-[n-(3,3-dimetilbutil)-l- alfa-aspartil]-l-fenilamina 1 - metilico, bebida sin alcohol carbonatada,bebida de jugo, bebida envasada caliente y bebida deportiva de bajas calorias.

Also Published As

Publication number Publication date
ATE248526T1 (de) 2003-09-15
AU754433B2 (en) 2002-11-14
EP1139794B1 (en) 2003-09-03
JP2002524098A (ja) 2002-08-06
EP1139794A1 (en) 2001-10-10
DE69911056D1 (de) 2003-10-09
US6214402B1 (en) 2001-04-10
AU6150599A (en) 2000-04-03
JP4678949B2 (ja) 2011-04-27
ES2207289T3 (es) 2004-05-16
DE69911056T2 (de) 2004-06-03
CA2344444A1 (en) 2000-03-23
WO2000015050A1 (en) 2000-03-23

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Effective date: 20110916