CA2341314A1 - Procede d'etude d'interactions de proteines in vivo - Google Patents

Procede d'etude d'interactions de proteines in vivo Download PDF

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Publication number
CA2341314A1
CA2341314A1 CA002341314A CA2341314A CA2341314A1 CA 2341314 A1 CA2341314 A1 CA 2341314A1 CA 002341314 A CA002341314 A CA 002341314A CA 2341314 A CA2341314 A CA 2341314A CA 2341314 A1 CA2341314 A1 CA 2341314A1
Authority
CA
Canada
Prior art keywords
protein
complexed
acceptor fluorophore
leu
pro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002341314A
Other languages
English (en)
Inventor
Aladar A. Szalay
Yubao Wang
Gefu Wang-Pruski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Loma Linda University
Original Assignee
Loma Linda University
Aladar A. Szalay
Yubao Wang
Gefu Wang-Pruski
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Loma Linda University, Aladar A. Szalay, Yubao Wang, Gefu Wang-Pruski filed Critical Loma Linda University
Publication of CA2341314A1 publication Critical patent/CA2341314A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1055—Protein x Protein interaction, e.g. two hybrid selection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
CA002341314A 1998-09-03 1999-09-02 Procede d'etude d'interactions de proteines in vivo Abandoned CA2341314A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US9906898P 1998-09-03 1998-09-03
US60/099,068 1998-09-03
US13583599P 1999-05-24 1999-05-24
US60/135,835 1999-05-24
PCT/US1999/020207 WO2000014271A1 (fr) 1998-09-03 1999-09-02 PROCEDE D'ETUDE D'INTERACTIONS DE PROTEINES $i(IN VIVO)

Publications (1)

Publication Number Publication Date
CA2341314A1 true CA2341314A1 (fr) 2000-03-16

Family

ID=26795497

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002341314A Abandoned CA2341314A1 (fr) 1998-09-03 1999-09-02 Procede d'etude d'interactions de proteines in vivo

Country Status (6)

Country Link
EP (1) EP1109931A4 (fr)
JP (1) JP2002524087A (fr)
CN (1) CN1160470C (fr)
AU (1) AU752675B2 (fr)
CA (1) CA2341314A1 (fr)
WO (1) WO2000014271A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004003150A2 (fr) 2002-06-26 2004-01-08 Yale University Modulateurs et modulation de l'interaction entre les rgm et la neogenine
DE602004020855D1 (de) 2003-11-20 2009-06-10 Hoffmann La Roche Spezifische Marker für Stoffwechselssyndrome
CN1920021B (zh) * 2005-08-24 2010-05-05 中国医学科学院基础医学研究所 胰岛素样生长因子结合蛋白-6介导的有活性胰岛素样生长因子-ⅱ的制备方法
JP2009510002A (ja) 2005-09-30 2009-03-12 アボット ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト 反発誘導分子（ｒｇｍ）タンパク質ファミリーのタンパク質の結合ドメイン、及びその機能的断片、及びそれらの使用
US8962803B2 (en) 2008-02-29 2015-02-24 AbbVie Deutschland GmbH & Co. KG Antibodies against the RGM A protein and uses thereof
US8647887B2 (en) 2009-01-29 2014-02-11 Commonwealth Scientific And Industrial Research Organisation Measuring G protein coupled receptor activation
CN101620233B (zh) * 2009-05-27 2012-10-31 华中科技大学 一种蛋白质相互作用的检测方法
MX2012006560A (es) 2009-12-08 2012-10-05 Abbott Gmbh & Co Kg Anticuerpos monoclonales contra la proteina rgm a para utilizarse en el tratamiento de degeneracion de capa de fibra de nervio retinal.
WO2011083147A1 (fr) 2010-01-08 2011-07-14 Cemm-Forschungsinstitut Für Molekulare Medizin Gmbh Inhibition de wave1 dans l'intervention médicale de maladies inflammatoires et/ou d'infections causées par un pathogène
WO2011131626A1 (fr) 2010-04-19 2011-10-27 Medizinische Universität Innsbruck Tmem195 code pour l'activité alkylglycérol monooxygénase dépendante de la tétrahydrobioptérine
PL2807192T3 (pl) 2012-01-27 2019-02-28 Abbvie Deutschland Kompozycja oraz sposób diagnostyki i leczenia chorób związanych ze zwyrodnieniem neurytów
CN102798717B (zh) * 2012-06-15 2014-11-26 杭州师范大学 一种o6-甲基鸟嘌呤-dna甲基转移酶活性检测方法
CN103616502B (zh) * 2013-09-12 2016-05-25 西北农林科技大学 基于细菌荧光素酶bret技术检测蛋白质相互作用的方法
US10415960B2 (en) 2015-04-06 2019-09-17 Worldvu Satellites Limited Elevation angle estimating system and method for user terminal placement
CA3022981A1 (fr) 2017-11-01 2019-05-01 Queen's University At Kingston Biocapteur bioluminescent de parcours hippo
CN110794129B (zh) * 2018-08-01 2020-12-01 清华大学 细胞内检测生物分子间相互作用及其调控因子的方法与所用试剂

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4604364A (en) * 1974-01-04 1986-08-05 Kosak Kenneth M Bioluminescent tracer composition and method of use in immunoassays
US4318707A (en) * 1978-11-24 1982-03-09 Syva Company Macromolecular fluorescent quencher particle in specific receptor assays
DK487784A (da) * 1983-10-13 1985-04-14 Univ Georgia Immunoassay
US5683888A (en) * 1989-07-22 1997-11-04 University Of Wales College Of Medicine Modified bioluminescent proteins and their use
US5292658A (en) * 1989-12-29 1994-03-08 University Of Georgia Research Foundation, Inc. Boyd Graduate Studies Research Center Cloning and expressions of Renilla luciferase
AT401526B (de) * 1993-02-10 1996-09-25 Scheirer Winfried Reagenzlösung zur stabilisierung der lumineszenz bei der luciferasemessung
US5491084A (en) * 1993-09-10 1996-02-13 The Trustees Of Columbia University In The City Of New York Uses of green-fluorescent protein
US5605793A (en) * 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5976796A (en) * 1996-10-04 1999-11-02 Loma Linda University Construction and expression of renilla luciferase and green fluorescent protein fusion genes
US5891646A (en) * 1997-06-05 1999-04-06 Duke University Methods of assaying receptor activity and constructs useful in such methods
DE69928255T2 (de) * 1998-06-16 2006-11-09 PerkinElmer BioSignal Inc., Montréal Biolumineszentes resonanz-energie-transfersystem (bret) und seine anwendung

Also Published As

Publication number Publication date
EP1109931A4 (fr) 2004-12-15
CN1323353A (zh) 2001-11-21
EP1109931A1 (fr) 2001-06-27
JP2002524087A (ja) 2002-08-06
CN1160470C (zh) 2004-08-04
AU752675B2 (en) 2002-09-26
WO2000014271A1 (fr) 2000-03-16
AU5805699A (en) 2000-03-27

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued