CA2335134A1 - Therapeutic combinations of (selective) estrogen receptor modulators (serm) and growth hormone secretagogues (ghs) for treating musculoskeletal frailty - Google Patents

Therapeutic combinations of (selective) estrogen receptor modulators (serm) and growth hormone secretagogues (ghs) for treating musculoskeletal frailty Download PDF

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Publication number
CA2335134A1
CA2335134A1 CA002335134A CA2335134A CA2335134A1 CA 2335134 A1 CA2335134 A1 CA 2335134A1 CA 002335134 A CA002335134 A CA 002335134A CA 2335134 A CA2335134 A CA 2335134A CA 2335134 A1 CA2335134 A1 CA 2335134A1
Authority
CA
Canada
Prior art keywords
bone
phenyl
oxo
compound
kit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002335134A
Other languages
English (en)
French (fr)
Inventor
Hua Zhu Ke
Mei Li
David Duane Thompson
Lydia Codetta Pan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2335134A1 publication Critical patent/CA2335134A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
CA002335134A 1998-06-16 1999-06-16 Therapeutic combinations of (selective) estrogen receptor modulators (serm) and growth hormone secretagogues (ghs) for treating musculoskeletal frailty Abandoned CA2335134A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8946998P 1998-06-16 1998-06-16
US60/089,469 1998-06-16
PCT/IB1999/001117 WO1999065486A1 (en) 1998-06-16 1999-06-16 Therapeutic combinations of (selective) estrogen receptor modulators (serm) and growth hormone secretagogues (ghs) for treating musculoskeletal frailty

Publications (1)

Publication Number Publication Date
CA2335134A1 true CA2335134A1 (en) 1999-12-23

Family

ID=22217825

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002335134A Abandoned CA2335134A1 (en) 1998-06-16 1999-06-16 Therapeutic combinations of (selective) estrogen receptor modulators (serm) and growth hormone secretagogues (ghs) for treating musculoskeletal frailty

Country Status (30)

Country Link
EP (1) EP1087764A1 (no)
JP (1) JP2002518326A (no)
KR (1) KR20010052852A (no)
CN (1) CN1301160A (no)
AP (1) AP9901582A0 (no)
AR (1) AR018869A1 (no)
AU (1) AU4054799A (no)
BG (1) BG105041A (no)
BR (1) BR9911324A (no)
CA (1) CA2335134A1 (no)
CO (1) CO5070587A1 (no)
EA (1) EA200001186A1 (no)
GT (1) GT199900087A (no)
HN (1) HN1999000097A (no)
HR (1) HRP20000859A2 (no)
HU (1) HUP0102505A3 (no)
ID (1) ID27599A (no)
IL (1) IL138630A0 (no)
IS (1) IS5691A (no)
MA (1) MA26652A1 (no)
NO (1) NO20006312L (no)
OA (1) OA11505A (no)
PA (1) PA8475901A1 (no)
PE (1) PE20000646A1 (no)
PL (1) PL344981A1 (no)
SK (1) SK18912000A3 (no)
TN (1) TNSN99124A1 (no)
TR (1) TR200003544T2 (no)
WO (1) WO1999065486A1 (no)
ZA (1) ZA993975B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000047735A2 (en) * 1999-02-08 2000-08-17 Mcgill University NON-HUMAN TRANSGENIC ANIMAL WHOSE GERM CELLS AND SOMATIC CELLS CONTAIN A KNOCKOUT MUTATION IN DNA ENCODING ORPHAN NUCLEAR RECEPTOR ERRalpha
ES2274854T3 (es) 2000-05-08 2007-06-01 Pfizer Products Inc. Resolucion enzimatica de moduladores selectivos del receptor de estrogeno.
JP2004507502A (ja) 2000-08-30 2004-03-11 ファイザー・プロダクツ・インク 成長ホルモン分泌促進物質のための徐放性製剤
IL145106A0 (en) * 2000-08-30 2002-06-30 Pfizer Prod Inc Intermittent administration of a geowth hormone secretagogue
US7476653B2 (en) 2003-06-18 2009-01-13 Tranzyme Pharma, Inc. Macrocyclic modulators of the ghrelin receptor
WO2006024931A2 (en) * 2004-08-31 2006-03-09 Pfizer Products Inc. Therapeutic combinations comprising a selective estrogen receptor modulator and a selective androgen receptor modulator
CU23558A1 (es) 2006-02-28 2010-07-20 Ct Ingenieria Genetica Biotech Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento
JP2010518090A (ja) 2007-02-09 2010-05-27 トランザイム・ファーマ，インコーポレイテッド 大環状グレリン受容体修飾因子およびその使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA51676C2 (uk) * 1995-11-02 2002-12-16 Пфайзер Інк. (-)цис-6(s)-феніл-5(r)[4-(2-піролідин-1-ілетокси)феніл]-5,6,7,8-тетрагідронафталін-2-ол d-тартрат, спосіб його одержання, спосіб лікування захворювань, що піддаються лікуванню агоністами естрогену, та фармацевтична композиція
TW432073B (en) * 1995-12-28 2001-05-01 Pfizer Pyrazolopyridine compounds
HN1996000101A (es) * 1996-02-28 1997-06-26 Inc Pfizer Terapia combinada para la osteoporosis

Also Published As

Publication number Publication date
ID27599A (id) 2001-04-12
CO5070587A1 (es) 2001-08-28
JP2002518326A (ja) 2002-06-25
NO20006312D0 (no) 2000-12-12
OA11505A (en) 2004-05-07
ZA993975B (en) 2000-12-15
PL344981A1 (en) 2001-11-19
HUP0102505A3 (en) 2002-12-28
HRP20000859A2 (en) 2001-04-30
GT199900087A (es) 2000-12-07
TNSN99124A1 (fr) 2005-11-10
TR200003544T2 (tr) 2001-04-20
KR20010052852A (ko) 2001-06-25
NO20006312L (no) 2000-12-12
PE20000646A1 (es) 2000-08-05
CN1301160A (zh) 2001-06-27
HUP0102505A2 (hu) 2001-11-28
IL138630A0 (en) 2001-10-31
AR018869A1 (es) 2001-12-12
EP1087764A1 (en) 2001-04-04
BG105041A (en) 2001-08-31
MA26652A1 (fr) 2004-12-20
SK18912000A3 (sk) 2001-10-08
AP9901582A0 (en) 1999-06-30
EA200001186A1 (ru) 2001-06-25
PA8475901A1 (es) 2000-05-24
WO1999065486A1 (en) 1999-12-23
IS5691A (is) 2000-10-27
AU4054799A (en) 2000-01-05
BR9911324A (pt) 2001-04-03
HN1999000097A (es) 1999-11-03

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued