CA2304498C - Aerosol medication delivery apparatus and system - Google Patents
Aerosol medication delivery apparatus and system Download PDFInfo
- Publication number
- CA2304498C CA2304498C CA002304498A CA2304498A CA2304498C CA 2304498 C CA2304498 C CA 2304498C CA 002304498 A CA002304498 A CA 002304498A CA 2304498 A CA2304498 A CA 2304498A CA 2304498 C CA2304498 C CA 2304498C
- Authority
- CA
- Canada
- Prior art keywords
- chamber housing
- medication
- canister
- aerosol
- mouthpiece
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229940079593 drug Drugs 0.000 title claims abstract description 112
- 239000003814 drug Substances 0.000 title claims abstract description 112
- 239000000443 aerosol Substances 0.000 title claims abstract description 94
- 239000003380 propellant Substances 0.000 claims abstract description 16
- 238000011144 upstream manufacturing Methods 0.000 claims description 9
- 229940071648 metered dose inhaler Drugs 0.000 claims 6
- 230000007246 mechanism Effects 0.000 abstract description 12
- 230000008878 coupling Effects 0.000 abstract description 9
- 238000010168 coupling process Methods 0.000 abstract description 9
- 238000005859 coupling reaction Methods 0.000 abstract description 9
- 238000003860 storage Methods 0.000 abstract description 7
- 239000002245 particle Substances 0.000 description 44
- 239000000203 mixture Substances 0.000 description 10
- 239000000725 suspension Substances 0.000 description 9
- 229960000676 flunisolide Drugs 0.000 description 8
- 238000009472 formulation Methods 0.000 description 8
- 210000004072 lung Anatomy 0.000 description 8
- MIXMJCQRHVAJIO-TZHJZOAOSA-N qk4dys664x Chemical compound O.C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O.C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]2(C)C[C@@H]1O MIXMJCQRHVAJIO-TZHJZOAOSA-N 0.000 description 8
- 238000000151 deposition Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 230000008021 deposition Effects 0.000 description 5
- 230000003434 inspiratory effect Effects 0.000 description 5
- 230000008901 benefit Effects 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 230000002411 adverse Effects 0.000 description 3
- 239000003570 air Substances 0.000 description 3
- 239000003246 corticosteroid Substances 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 210000003300 oropharynx Anatomy 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 229960001334 corticosteroids Drugs 0.000 description 2
- 239000013536 elastomeric material Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 206010001382 Adrenal suppression Diseases 0.000 description 1
- 206010013952 Dysphonia Diseases 0.000 description 1
- 208000010473 Hoarseness Diseases 0.000 description 1
- 206010050346 Oropharyngeal candidiasis Diseases 0.000 description 1
- 102000004067 Osteocalcin Human genes 0.000 description 1
- 108090000573 Osteocalcin Proteins 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000012080 ambient air Substances 0.000 description 1
- 238000000889 atomisation Methods 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 150000005828 hydrofluoroalkanes Chemical class 0.000 description 1
- 230000003116 impacting effect Effects 0.000 description 1
- 238000002664 inhalation therapy Methods 0.000 description 1
- 229940125369 inhaled corticosteroids Drugs 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 229940124624 oral corticosteroid Drugs 0.000 description 1
- 230000011164 ossification Effects 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- -1 polypropylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0086—Inhalation chambers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/003—Particle size control by passing the aerosol trough sieves or filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2689736A CA2689736C (en) | 1997-09-26 | 1998-09-16 | Aerosol medication delivery apparatus and system |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/938,686 US6345617B1 (en) | 1997-09-26 | 1997-09-26 | Aerosol medication delivery apparatus and system |
| US08/938,686 | 1997-09-26 | ||
| PCT/IB1998/001681 WO1999016490A1 (en) | 1997-09-26 | 1998-09-16 | Aerosol medication delivery apparatus and system |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2689736A Division CA2689736C (en) | 1997-09-26 | 1998-09-16 | Aerosol medication delivery apparatus and system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2304498A1 CA2304498A1 (en) | 1999-04-08 |
| CA2304498C true CA2304498C (en) | 2010-01-05 |
Family
ID=25471799
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2790025A Abandoned CA2790025A1 (en) | 1997-09-26 | 1998-09-16 | Aerosol medication delivery apparatus and system |
| CA002304498A Expired - Lifetime CA2304498C (en) | 1997-09-26 | 1998-09-16 | Aerosol medication delivery apparatus and system |
| CA2689736A Expired - Lifetime CA2689736C (en) | 1997-09-26 | 1998-09-16 | Aerosol medication delivery apparatus and system |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2790025A Abandoned CA2790025A1 (en) | 1997-09-26 | 1998-09-16 | Aerosol medication delivery apparatus and system |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2689736A Expired - Lifetime CA2689736C (en) | 1997-09-26 | 1998-09-16 | Aerosol medication delivery apparatus and system |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6345617B1 (enExample) |
| EP (1) | EP1019127B1 (enExample) |
| JP (2) | JP2001518323A (enExample) |
| AR (1) | AR013968A1 (enExample) |
| AU (1) | AU739002B2 (enExample) |
| CA (3) | CA2790025A1 (enExample) |
| DE (1) | DE69819541T2 (enExample) |
| WO (1) | WO1999016490A1 (enExample) |
| ZA (1) | ZA988203B (enExample) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5823179A (en) * | 1996-02-13 | 1998-10-20 | 1263152 Ontario Inc. | Nebulizer apparatus and method |
| US6293279B1 (en) | 1997-09-26 | 2001-09-25 | Trudell Medical International | Aerosol medication delivery apparatus and system |
| US6345617B1 (en) | 1997-09-26 | 2002-02-12 | 1263152 Ontario Inc. | Aerosol medication delivery apparatus and system |
| US7967011B2 (en) * | 1997-11-14 | 2011-06-28 | Astrazeneca Ab | Inhalation device |
| SE9704185D0 (sv) * | 1997-11-14 | 1997-11-14 | Astra Pharma Prod | Inhalation device |
| US20060213505A1 (en) * | 1997-11-14 | 2006-09-28 | Astrazeneca Ab | Inhalation device |
| US6397837B1 (en) * | 1999-07-22 | 2002-06-04 | Martin W. Ferris | Inhaler assistive device |
| GB2360219A (en) | 2000-03-18 | 2001-09-19 | Astrazeneca Uk Ltd | Inhaler |
| WO2001076671A2 (en) | 2000-04-11 | 2001-10-18 | Trudell Medical International | Aerosol delivery apparatus with positive expiratory pressure capacity |
| US6501052B2 (en) * | 2000-12-22 | 2002-12-31 | Chrysalis Technologies Incorporated | Aerosol generator having multiple heating zones and methods of use thereof |
| US6698422B2 (en) * | 2001-03-12 | 2004-03-02 | Birdsong Medical Devices, Inc. | Canister inhaler having a spacer and easy to operate lever mechanism and a flexible, elastic mouthpiece |
| ES2375333T3 (es) | 2001-03-20 | 2012-02-28 | Trudell Medical International | Aparato nebulizador. |
| PT1414508E (pt) * | 2001-06-26 | 2011-07-08 | Norton Healthcare Ltd | Um accionador de aerossol melhorado |
| US7767872B2 (en) * | 2001-09-06 | 2010-08-03 | Mpg Biotechnologies, Llc | Thimerosal removal device |
| US8440791B2 (en) * | 2001-09-06 | 2013-05-14 | Mgp Biotechnologies, Llc | Thimerosal removal device |
| US20030205226A1 (en) | 2002-05-02 | 2003-11-06 | Pre Holding, Inc. | Aerosol medication inhalation system |
| AU2003225071A1 (en) * | 2002-05-03 | 2003-11-17 | Trudell Medical International | Aerosol medication delivery apparatus with narrow orifice |
| US6904908B2 (en) | 2002-05-21 | 2005-06-14 | Trudell Medical International | Visual indicator for an aerosol medication delivery apparatus and system |
| US7360537B2 (en) * | 2003-04-16 | 2008-04-22 | Trudell Medical International | Antistatic medication delivery apparatus |
| US8235036B2 (en) * | 2005-09-09 | 2012-08-07 | Vedat Obuz | Portable universal inhaler system |
| US20070074718A1 (en) * | 2005-10-04 | 2007-04-05 | Sp Medical Llc | Metered dose inhaler having spacing device |
| JP2009543658A (ja) * | 2006-07-14 | 2009-12-10 | アストラゼネカ・アクチエボラーグ | 乾燥粉末状の薬を投与するための吸入装置及び配送装置 |
| WO2008024375A2 (en) | 2006-08-21 | 2008-02-28 | Trudell Medical International | Respiratory muscle endurance training device and method for the use thereof |
| JP2011505882A (ja) * | 2007-12-08 | 2011-03-03 | エフティミウ，ディミトリオス | 増幅器およびバイブレータ付個人用エアフィルタ |
| CA2716511C (en) * | 2008-02-21 | 2015-06-02 | Trudell Medical International | Respiratory muscle endurance training device and method for the use thereof |
| US8251876B2 (en) * | 2008-04-22 | 2012-08-28 | Hill-Rom Services, Inc. | Breathing exercise apparatus |
| US8539951B1 (en) | 2008-05-27 | 2013-09-24 | Trudell Medical International | Oscillating positive respiratory pressure device |
| US8327849B2 (en) * | 2008-10-28 | 2012-12-11 | Trudell Medical International | Oscillating positive expiratory pressure device |
| US9149589B2 (en) | 2009-02-23 | 2015-10-06 | Trudell Medical International | Method and device for performing orientation dependent oscillating positive expiratory pressure therapy |
| US8485179B1 (en) | 2009-02-23 | 2013-07-16 | Trudell Medical International | Oscillating positive expiratory pressure device |
| US9364621B2 (en) * | 2010-09-21 | 2016-06-14 | Koninklijke Philips N.V. | Valved holding chamber including valve retention system |
| AU2011335408B2 (en) | 2010-11-30 | 2015-06-11 | Teva Pharmaceutical Industries Ltd. | Inhalers and housing caps for inhalers |
| BR112013031207B1 (pt) | 2011-06-06 | 2020-12-08 | Trudell Medical International | dispositivo de tratamento respiratório |
| US8695589B2 (en) | 2011-12-06 | 2014-04-15 | Anthony J. Mullane | Inhaler assist device |
| US9180271B2 (en) | 2012-03-05 | 2015-11-10 | Hill-Rom Services Pte. Ltd. | Respiratory therapy device having standard and oscillatory PEP with nebulizer |
| US9364622B2 (en) | 2012-04-20 | 2016-06-14 | Fsc Laboratories, Inc. | Inhalation devices and systems and methods including the same |
| US9517315B2 (en) | 2012-11-30 | 2016-12-13 | Trudell Medical International | Oscillating positive expiratory pressure device |
| CA151549S (en) | 2013-02-14 | 2014-06-04 | Clement Clarke Int Ltd | Spacer for an asthma inhaler |
| USD735316S1 (en) | 2013-03-11 | 2015-07-28 | Fsc Laboratories, Inc. | Inhalation spacer |
| TWI568463B (zh) | 2013-07-12 | 2017-02-01 | Ｈ 斯圖爾特 坎貝爾 | 用於吸入器之吹嘴 |
| CA2915949C (en) | 2013-07-12 | 2020-01-28 | Trudell Medical International | Huff cough simulation device |
| US9849257B2 (en) | 2013-08-22 | 2017-12-26 | Trudell Medical International | Oscillating positive respiratory pressure device |
| JP5990866B2 (ja) * | 2013-10-11 | 2016-09-14 | 株式会社リーチハイアー | 経口粉末の吸入補助器具 |
| US10363383B2 (en) | 2014-02-07 | 2019-07-30 | Trudell Medical International | Pressure indicator for an oscillating positive expiratory pressure device |
| GB201408561D0 (en) * | 2014-05-14 | 2014-06-25 | The Technology Partnership Plc | Aerosolisation engine for liquid drug delivery |
| USD748242S1 (en) * | 2014-07-11 | 2016-01-26 | H. Stuart Campbell | Inhaler mouthpiece |
| US10004872B1 (en) | 2015-03-06 | 2018-06-26 | D R Burton Healthcare, Llc | Positive expiratory pressure device having an oscillating valve |
| CN205924624U (zh) * | 2015-05-12 | 2017-02-08 | 深圳瑞之谷医疗科技有限公司 | 药杯组件及医用雾化器 |
| EP4134118B1 (en) | 2015-07-30 | 2024-11-27 | Trudell Medical International Inc. | Combined respiratory muscle training and oscillating positive expiratory pressure device |
| USD778429S1 (en) | 2015-09-02 | 2017-02-07 | Trudell Medical International | Respiratory treatment device |
| USD780906S1 (en) | 2015-09-02 | 2017-03-07 | Trudell Medical International | Respiratory treatment device |
| EP3383465B1 (en) | 2015-12-04 | 2021-02-03 | Trudell Medical International | Huff cough simulation device |
| CA3020577C (en) | 2016-05-19 | 2023-08-01 | Trudell Medical International | Smart valved holding chamber |
| US10537693B2 (en) | 2016-05-30 | 2020-01-21 | Medical Developments International Limited | Collapsible disposable spacer for metered dose inhalers |
| US10881818B2 (en) | 2016-07-08 | 2021-01-05 | Trudell Medical International | Smart oscillating positive expiratory pressure device |
| US10786638B2 (en) | 2016-07-08 | 2020-09-29 | Trudell Medical International | Nebulizer apparatus and method |
| WO2018102870A1 (en) * | 2016-12-06 | 2018-06-14 | Heath Rainbow | Inhaler housing |
| JP7093353B2 (ja) | 2016-12-09 | 2022-06-29 | トゥルーデル メディカル インターナショナル | スマートネブライザ |
| CA3240360A1 (en) | 2017-05-03 | 2018-11-08 | Trudell Medical International | Combined oscillating positive expiratory pressure therapy and huff cough simulation device |
| DE102017219364B4 (de) | 2017-10-27 | 2022-07-07 | Weiss Klimatechnik Gmbh | Klimagerät und Verfahren zur Desinfektion eines Klimageräts |
| JP7312754B2 (ja) | 2018-01-04 | 2023-07-21 | トゥルーデル メディカル インターナショナル | スマート振動型呼気陽圧器具 |
| US10953278B2 (en) | 2018-02-02 | 2021-03-23 | Trudell Medical International | Oscillating positive expiratory pressure device |
| WO2019236662A1 (en) | 2018-06-05 | 2019-12-12 | Teleflex Medical Incorporated | Valved spacer for inhalation device |
| WO2020102229A1 (en) | 2018-11-14 | 2020-05-22 | Loop Laboratories, LLC | Inhalant dispensing system and apparatus |
| KR20220039657A (ko) * | 2019-05-24 | 2022-03-29 | 블루 오션 그룹 엘엘씨 | 정량식 분무흡입기용 소형 스페이서 |
| GB201909172D0 (en) * | 2019-06-26 | 2019-08-07 | Royal College Of Art | Inhaler |
| EP4003471B1 (en) | 2019-07-24 | 2024-09-04 | Trudell Medical International Inc. | Portable holding chamber for pressurized metered dose inhaler |
| AU2020338979B2 (en) | 2019-08-27 | 2025-09-25 | Trudell Medical International Inc. | Smart oscillating positive expiratory pressure device |
| USD1010101S1 (en) | 2020-09-18 | 2024-01-02 | Trudell Medical International | Holding chamber |
Family Cites Families (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2670739A (en) | 1951-07-02 | 1954-03-02 | Charles M Mcneill | Inhaler |
| GB975754A (en) | 1961-05-15 | 1964-11-18 | Pfizer Ltd | Medicament administering apparatus |
| FR1322998A (fr) * | 1962-02-23 | 1963-04-05 | Perfectionnements aux dispositifs de production d'aérosols | |
| GB1017032A (en) | 1963-12-12 | 1966-01-12 | Aerosmoke Ltd | Aerosol compositions |
| DE1972590U (de) | 1964-06-15 | 1967-11-16 | Asmund S Laerdal | Ventil fuer wiederbelebungsapparate. |
| US3565071A (en) | 1968-09-19 | 1971-02-23 | Abbott Lab | Self-regulating therapeutic inhaler |
| US3809084A (en) | 1970-02-16 | 1974-05-07 | American Cyanamid Co | Pressurized portable dispenser |
| US3643686A (en) | 1970-10-21 | 1972-02-22 | Ewald Koegel | High-velocity breathing valve |
| US3838686A (en) | 1971-10-14 | 1974-10-01 | G Szekely | Aerosol apparatus for inhalation therapy |
| US3809294A (en) | 1973-06-27 | 1974-05-07 | American Cyanamid Co | Dispensing lung contacting powdered medicaments |
| US3897779A (en) | 1973-06-27 | 1975-08-05 | American Cyanamid Co | Triamcinolone acetonide inhalation therapy |
| US3994421A (en) | 1975-09-29 | 1976-11-30 | American Cyanamid Company | Unitary therapeutic aerosol dispenser |
| SE411705B (sv) | 1976-11-09 | 1980-02-04 | Draco Ab | Anordning for generering av en avskermad, vesentligen drivmedelsfri aerosol |
| GB2000555A (en) | 1977-07-01 | 1979-01-10 | Ici Ltd | Aerosol dispensing device |
| GR69682B (enExample) | 1978-09-11 | 1982-07-08 | Newhouse Michael T | |
| SE415957B (sv) | 1979-02-16 | 1980-11-17 | Draco Ab | Aerosolinhalationsanordning |
| SE433443B (sv) * | 1981-09-15 | 1984-05-28 | Draco Ab | Aerosolinhalationsanordning |
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| EP0134847B1 (en) | 1983-08-02 | 1987-05-27 | Trutek Research Inc. | Inhalation valve |
| FI69962C (fi) | 1983-12-28 | 1986-09-12 | Huhtamaeki Oy | Inhalationsanordning |
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| SE453566B (sv) * | 1986-03-07 | 1988-02-15 | Draco Ab | Anordning vid pulverinhalatorer |
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| JPS63143081A (ja) | 1986-12-05 | 1988-06-15 | メクト株式会社 | 吸入器 |
| US4796614A (en) * | 1987-02-26 | 1989-01-10 | Trutek Research, Inc. | Collapsible inhalation valve |
| JPH0199570A (ja) * | 1987-09-30 | 1989-04-18 | Bootran Medical Technol Inc | 吸入装置と吸入方法 |
| IT1217890B (it) | 1988-06-22 | 1990-03-30 | Chiesi Farma Spa | Dispositivo per l'inalazione di aerosol dosati |
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| IT1244441B (it) | 1990-09-13 | 1994-07-15 | Chiesi Farma Spa | Dispositivo per l'inalazione boccale di farmaci aerosol |
| GB9021433D0 (en) * | 1990-10-02 | 1990-11-14 | Atomic Energy Authority Uk | Power inhaler |
| US5040527A (en) | 1990-12-18 | 1991-08-20 | Healthscan Products Inc. | Metered dose inhalation unit with slide means |
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-
1997
- 1997-09-26 US US08/938,686 patent/US6345617B1/en not_active Expired - Lifetime
-
1998
- 1998-09-08 ZA ZA9808203A patent/ZA988203B/xx unknown
- 1998-09-16 DE DE69819541T patent/DE69819541T2/de not_active Expired - Lifetime
- 1998-09-16 WO PCT/IB1998/001681 patent/WO1999016490A1/en not_active Ceased
- 1998-09-16 JP JP2000513619A patent/JP2001518323A/ja active Pending
- 1998-09-16 CA CA2790025A patent/CA2790025A1/en not_active Abandoned
- 1998-09-16 EP EP98946684A patent/EP1019127B1/en not_active Expired - Lifetime
- 1998-09-16 CA CA002304498A patent/CA2304498C/en not_active Expired - Lifetime
- 1998-09-16 AU AU93644/98A patent/AU739002B2/en not_active Expired
- 1998-09-16 CA CA2689736A patent/CA2689736C/en not_active Expired - Lifetime
- 1998-09-25 AR ARP980104800A patent/AR013968A1/es unknown
-
2009
- 2009-10-09 JP JP2009235307A patent/JP5137929B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999016490A1 (en) | 1999-04-08 |
| JP2001518323A (ja) | 2001-10-16 |
| DE69819541D1 (de) | 2003-12-11 |
| JP2010046500A (ja) | 2010-03-04 |
| EP1019127A1 (en) | 2000-07-19 |
| AR013968A1 (es) | 2001-01-31 |
| AU739002B2 (en) | 2001-10-04 |
| EP1019127B1 (en) | 2003-11-05 |
| DE69819541T2 (de) | 2004-04-15 |
| AU9364498A (en) | 1999-04-23 |
| ZA988203B (en) | 2000-03-22 |
| CA2790025A1 (en) | 1999-04-08 |
| US6345617B1 (en) | 2002-02-12 |
| CA2304498A1 (en) | 1999-04-08 |
| CA2689736C (en) | 2012-12-18 |
| CA2689736A1 (en) | 1999-04-08 |
| JP5137929B2 (ja) | 2013-02-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20180917 |