CA2291721C - Ribosome complexes as selection particles for in vitro display and evolution of proteins - Google Patents

Ribosome complexes as selection particles for in vitro display and evolution of proteins Download PDF

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Publication number
CA2291721C
CA2291721C CA2291721A CA2291721A CA2291721C CA 2291721 C CA2291721 C CA 2291721C CA 2291721 A CA2291721 A CA 2291721A CA 2291721 A CA2291721 A CA 2291721A CA 2291721 C CA2291721 C CA 2291721C
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CA
Canada
Prior art keywords
mrna
protein
peptide
complexed
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2291721A
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English (en)
French (fr)
Other versions
CA2291721A1 (en
Inventor
Michael John Taussig
Mingyue He
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Crescendo Biologics Ltd
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Crescendo Biologics Ltd
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27268863&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2291721(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9710829.4A external-priority patent/GB9710829D0/en
Priority claimed from GBGB9724850.4A external-priority patent/GB9724850D0/en
Priority claimed from GBGB9804195.7A external-priority patent/GB9804195D0/en
Application filed by Crescendo Biologics Ltd filed Critical Crescendo Biologics Ltd
Publication of CA2291721A1 publication Critical patent/CA2291721A1/en
Application granted granted Critical
Publication of CA2291721C publication Critical patent/CA2291721C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1041—Ribosome/Polysome display, e.g. SPERT, ARM
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
CA2291721A 1997-05-28 1998-05-28 Ribosome complexes as selection particles for in vitro display and evolution of proteins Expired - Fee Related CA2291721C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GBGB9710829.4A GB9710829D0 (en) 1997-05-28 1997-05-28 Selection particles for in vitro display and evolution of antibody combining sites
GBGB9724850.4A GB9724850D0 (en) 1997-11-26 1997-11-26 Selection particles for in vitro display and evolution of antibody combining sites
GB9724850.4 1998-02-28
GBGB9804195.7A GB9804195D0 (en) 1998-02-28 1998-02-28 Selection particles for in vitro display and evolution of antibody combining sites
GB9710829.4 1998-02-28
GB9804195.7 1998-02-28
PCT/GB1998/001564 WO1998054312A1 (en) 1997-05-28 1998-05-28 Ribosome complexes as selection particles for in vitro display and evolution of proteins

Publications (2)

Publication Number Publication Date
CA2291721A1 CA2291721A1 (en) 1998-12-03
CA2291721C true CA2291721C (en) 2011-08-09

Family

ID=27268863

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2291721A Expired - Fee Related CA2291721C (en) 1997-05-28 1998-05-28 Ribosome complexes as selection particles for in vitro display and evolution of proteins

Country Status (10)

Country Link
US (1) US6620587B1 (enExample)
EP (1) EP0985032B2 (enExample)
JP (1) JP4060892B2 (enExample)
AT (1) ATE250668T1 (enExample)
CA (1) CA2291721C (enExample)
DE (1) DE69818458T3 (enExample)
DK (1) DK0985032T4 (enExample)
ES (1) ES2209145T5 (enExample)
PT (1) PT985032E (enExample)
WO (1) WO1998054312A1 (enExample)

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Also Published As

Publication number Publication date
DE69818458T2 (de) 2004-07-08
CA2291721A1 (en) 1998-12-03
WO1998054312A1 (en) 1998-12-03
US6620587B1 (en) 2003-09-16
DK0985032T4 (da) 2009-08-31
AU7666698A (en) 1998-12-30
ES2209145T5 (es) 2009-10-30
DK0985032T3 (da) 2004-02-02
EP0985032B1 (en) 2003-09-24
ATE250668T1 (de) 2003-10-15
EP0985032B2 (en) 2009-06-03
JP2002500514A (ja) 2002-01-08
DE69818458D1 (de) 2003-10-30
EP0985032A1 (en) 2000-03-15
DE69818458T3 (de) 2009-12-17
AU725957B2 (en) 2000-10-26
PT985032E (pt) 2004-02-27
JP4060892B2 (ja) 2008-03-12
ES2209145T3 (es) 2004-06-16

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