CA2272717A1 - Cephalosporin derivatives - Google Patents

Cephalosporin derivatives Download PDF

Info

Publication number
CA2272717A1
CA2272717A1 CA002272717A CA2272717A CA2272717A1 CA 2272717 A1 CA2272717 A1 CA 2272717A1 CA 002272717 A CA002272717 A CA 002272717A CA 2272717 A CA2272717 A CA 2272717A CA 2272717 A1 CA2272717 A1 CA 2272717A1
Authority
CA
Canada
Prior art keywords
group
alkyl
hydrogen
compound
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002272717A
Other languages
English (en)
French (fr)
Inventor
Oak K. Kim
Stanley V. D'andrea
Bing Y. Luh
Thomas W. Hudyma
Dane M. Springer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2272717A1 publication Critical patent/CA2272717A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002272717A 1996-11-27 1997-11-21 Cephalosporin derivatives Abandoned CA2272717A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3404696P 1996-11-27 1996-11-27
US60/034,046 1996-11-27
PCT/US1997/021785 WO1998023621A1 (en) 1996-11-27 1997-11-21 Cephalosporin derivatives

Publications (1)

Publication Number Publication Date
CA2272717A1 true CA2272717A1 (en) 1998-06-04

Family

ID=21873971

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002272717A Abandoned CA2272717A1 (en) 1996-11-27 1997-11-21 Cephalosporin derivatives

Country Status (17)

Country Link
EP (1) EP0966472A1 (cs)
JP (1) JP2001506607A (cs)
KR (1) KR20000057283A (cs)
CN (1) CN1238775A (cs)
AR (1) AR010650A1 (cs)
AU (1) AU734948B2 (cs)
BR (1) BR9713350A (cs)
CA (1) CA2272717A1 (cs)
CZ (1) CZ185399A3 (cs)
HU (1) HUP9903621A3 (cs)
IL (1) IL129437A0 (cs)
NO (1) NO992526D0 (cs)
NZ (1) NZ335892A (cs)
PL (1) PL334558A1 (cs)
TW (1) TW414796B (cs)
WO (1) WO1998023621A1 (cs)
ZA (1) ZA9710662B (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6265394B1 (en) * 1997-07-31 2001-07-24 Bristol-Myers Squibb Company Bis quaternary MRSA cephem derivatives
KR20020085180A (ko) * 2001-05-07 2002-11-16 주식회사 엘지생명과학 신규 세팔로스포린계 항생제 및 이의 제조 방법
KR20020085176A (ko) * 2001-05-07 2002-11-16 주식회사 엘지생명과학 신규 세팔로스포린계 항생제 및 이의 제조 방법
KR20020085181A (ko) * 2001-05-07 2002-11-16 주식회사 엘지생명과학 신규 세팔로스포린계 항생제 및 이의 제조 방법
KR20020085178A (ko) * 2001-05-07 2002-11-16 주식회사 엘지생명과학 신규 세팔로스포린계 항생제 및 이의 제조 방법
KR20030071311A (ko) * 2002-02-28 2003-09-03 주식회사 엘지생명과학 신규 세팔로스포린 화합물 및 그의 제조방법
US8895587B2 (en) * 2011-05-18 2014-11-25 Syngenta Participations Ag Insecticidal compounds based on arylthioacetamide derivatives
CN105131018B (zh) * 2015-09-23 2017-12-26 浙江华方药业股份有限公司 一种头孢替唑酸的制备方法
CN114957056A (zh) * 2021-02-20 2022-08-30 帕潘纳(北京)科技有限公司 制备3-甲基-2-氯-4-甲基磺酰基苯甲酸甲酯及其中间体的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3345366A (en) * 1967-02-15 1967-10-03 American Cyanamid Co Substituted 7-acetylamino cephalosporanic acids
US4148997A (en) * 1977-11-07 1979-04-10 Yeda Research And Development Co., Ltd. 7-[Sulfomethyl)phenyl]acetamidocephalosporin derivatives
US5567698A (en) * 1995-02-15 1996-10-22 Bristol-Myers Squibb Company Pyridinium thiomethyl substituted chepholosporin derivatives
US5620969A (en) * 1995-04-25 1997-04-15 Bristol-Myers Squibb Company Cephalosporin derviatives
AU1278197A (en) * 1995-12-20 1997-07-14 Bristol-Myers Squibb Company Cephalosporin derivatives

Also Published As

Publication number Publication date
JP2001506607A (ja) 2001-05-22
TW414796B (en) 2000-12-11
PL334558A1 (en) 2000-03-13
KR20000057283A (ko) 2000-09-15
HUP9903621A3 (en) 2001-05-28
AR010650A1 (es) 2000-06-28
NZ335892A (en) 2001-07-27
ZA9710662B (en) 1999-05-26
AU734948B2 (en) 2001-06-28
BR9713350A (pt) 2000-01-25
EP0966472A1 (en) 1999-12-29
NO992526L (no) 1999-05-26
NO992526D0 (no) 1999-05-26
EP0966472A4 (cs) 1999-12-29
IL129437A0 (en) 2000-02-17
HUP9903621A2 (hu) 2000-04-28
CZ185399A3 (cs) 1999-08-11
CN1238775A (zh) 1999-12-15
WO1998023621A1 (en) 1998-06-04
AU5365298A (en) 1998-06-22

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Legal Events

Date Code Title Description
FZDE Discontinued