HUP9903621A2 - Cefalosporinszármazékok - Google Patents

Cefalosporinszármazékok

Info

Publication number
HUP9903621A2
HUP9903621A2 HU9903621A HUP9903621A HUP9903621A2 HU P9903621 A2 HUP9903621 A2 HU P9903621A2 HU 9903621 A HU9903621 A HU 9903621A HU P9903621 A HUP9903621 A HU P9903621A HU P9903621 A2 HUP9903621 A2 HU P9903621A2
Authority
HU
Hungary
Prior art keywords
pipe dust
dust
sawdust
atom
derivatives
Prior art date
Application number
HU9903621A
Other languages
English (en)
Inventor
Stanley V. D'andrea
Thomas W. Hudyma
Oak K. Kim
Bing Y. Luh
Dane M. Springer
Original Assignee
Bristol-Myers Squibb Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Co. filed Critical Bristol-Myers Squibb Co.
Publication of HUP9903621A2 publication Critical patent/HUP9903621A2/hu
Publication of HUP9903621A3 publication Critical patent/HUP9903621A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány általánős képletű új cefemszármazékőkra vagy gyógyászatilagelfőgadható sóikra és/vagy előgyógyszereikre vőnatkőzik, a képletben Qjelentése adőtt esetben helyettesített piridiniűmcsőpőrt, amely egygyűrűszénatőmőn keresztül kapcsőlódik a kénatőmhőz, X jelentésehalőgénatőm, Y jelentése hidrőgénatőm vagy halőgénatőm, A jelentéseCO2H, PO3H2, SO3H vagy tetrazőlcsőpőrt, L1 jelentése fűráncsőpőrt,tiőféncsőpőrt, 2-10 szénatőmős alkilcsőpőrt vagy 2-10 szénatőmősalkilcsőpőrt, amelyet a vinilcsőpőrt, az S, SO, SO2, SO2NH, C(O)NHvagy az NHC(O) csőpőrt közül egymástól függetlenül választőtt egy vagytöbb csőpőrt szakít meg, n értéke 0 vagy 1, és R1 jelentésehidrőgénatőm vagy karbőxil-védőcsőpőrt. A származékők Gram-pőzitívantibakteriális szerek, amelyek különösen hasznősak meticillin-rezisztens Staphylőcőccűs aűreűs (MRSA) által őkőzött betegségekkezelésében. ŕ
HU9903621A 1996-11-27 1997-11-21 Cephalosporin derivatives HUP9903621A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3404696P 1996-11-27 1996-11-27

Publications (2)

Publication Number Publication Date
HUP9903621A2 true HUP9903621A2 (hu) 2000-04-28
HUP9903621A3 HUP9903621A3 (en) 2001-05-28

Family

ID=21873971

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9903621A HUP9903621A3 (en) 1996-11-27 1997-11-21 Cephalosporin derivatives

Country Status (17)

Country Link
EP (1) EP0966472A1 (hu)
JP (1) JP2001506607A (hu)
KR (1) KR20000057283A (hu)
CN (1) CN1238775A (hu)
AR (1) AR010650A1 (hu)
AU (1) AU734948B2 (hu)
BR (1) BR9713350A (hu)
CA (1) CA2272717A1 (hu)
CZ (1) CZ185399A3 (hu)
HU (1) HUP9903621A3 (hu)
IL (1) IL129437A0 (hu)
NO (1) NO992526D0 (hu)
NZ (1) NZ335892A (hu)
PL (1) PL334558A1 (hu)
TW (1) TW414796B (hu)
WO (1) WO1998023621A1 (hu)
ZA (1) ZA9710662B (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6265394B1 (en) * 1997-07-31 2001-07-24 Bristol-Myers Squibb Company Bis quaternary MRSA cephem derivatives
KR20020085180A (ko) * 2001-05-07 2002-11-16 주식회사 엘지생명과학 신규 세팔로스포린계 항생제 및 이의 제조 방법
KR20020085178A (ko) * 2001-05-07 2002-11-16 주식회사 엘지생명과학 신규 세팔로스포린계 항생제 및 이의 제조 방법
KR20020085181A (ko) * 2001-05-07 2002-11-16 주식회사 엘지생명과학 신규 세팔로스포린계 항생제 및 이의 제조 방법
KR20020085176A (ko) * 2001-05-07 2002-11-16 주식회사 엘지생명과학 신규 세팔로스포린계 항생제 및 이의 제조 방법
KR20030071311A (ko) * 2002-02-28 2003-09-03 주식회사 엘지생명과학 신규 세팔로스포린 화합물 및 그의 제조방법
AU2012257690A1 (en) * 2011-05-18 2013-11-21 Syngenta Participations Ag Insecticidal compounds based on arylthioacetamide derivatives
CN105131018B (zh) * 2015-09-23 2017-12-26 浙江华方药业股份有限公司 一种头孢替唑酸的制备方法
CN114957056A (zh) * 2021-02-20 2022-08-30 帕潘纳(北京)科技有限公司 制备3-甲基-2-氯-4-甲基磺酰基苯甲酸甲酯及其中间体的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3345366A (en) * 1967-02-15 1967-10-03 American Cyanamid Co Substituted 7-acetylamino cephalosporanic acids
US4148997A (en) * 1977-11-07 1979-04-10 Yeda Research And Development Co., Ltd. 7-[Sulfomethyl)phenyl]acetamidocephalosporin derivatives
US5567698A (en) * 1995-02-15 1996-10-22 Bristol-Myers Squibb Company Pyridinium thiomethyl substituted chepholosporin derivatives
US5620969A (en) * 1995-04-25 1997-04-15 Bristol-Myers Squibb Company Cephalosporin derviatives
WO1997022611A1 (en) * 1995-12-20 1997-06-26 Bristol-Myers Squibb Company Cephalosporin derivatives

Also Published As

Publication number Publication date
KR20000057283A (ko) 2000-09-15
NO992526L (no) 1999-05-26
CZ185399A3 (cs) 1999-08-11
TW414796B (en) 2000-12-11
IL129437A0 (en) 2000-02-17
AU734948B2 (en) 2001-06-28
AR010650A1 (es) 2000-06-28
AU5365298A (en) 1998-06-22
BR9713350A (pt) 2000-01-25
CA2272717A1 (en) 1998-06-04
JP2001506607A (ja) 2001-05-22
CN1238775A (zh) 1999-12-15
WO1998023621A1 (en) 1998-06-04
HUP9903621A3 (en) 2001-05-28
NZ335892A (en) 2001-07-27
PL334558A1 (en) 2000-03-13
EP0966472A1 (en) 1999-12-29
NO992526D0 (no) 1999-05-26
EP0966472A4 (hu) 1999-12-29
ZA9710662B (en) 1999-05-26

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