CA2271843A1 - Topical formulations containing as a therapeutic active agent fatty acids or fatty alcohols or monoglyceride derivatives thereof for treating of mucosa infections - Google Patents
Topical formulations containing as a therapeutic active agent fatty acids or fatty alcohols or monoglyceride derivatives thereof for treating of mucosa infections Download PDFInfo
- Publication number
- CA2271843A1 CA2271843A1 CA002271843A CA2271843A CA2271843A1 CA 2271843 A1 CA2271843 A1 CA 2271843A1 CA 002271843 A CA002271843 A CA 002271843A CA 2271843 A CA2271843 A CA 2271843A CA 2271843 A1 CA2271843 A1 CA 2271843A1
- Authority
- CA
- Canada
- Prior art keywords
- lipid
- pharmaceutical formulation
- titer
- formulation
- millimolar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 208000011580 syndromic disease Diseases 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- ILLKMACMBHTSHP-UHFFFAOYSA-N tetradecaethylene glycol Chemical compound OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO ILLKMACMBHTSHP-UHFFFAOYSA-N 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical class [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 230000036269 ulceration Effects 0.000 description 1
- PSVXZQVXSXSQRO-UHFFFAOYSA-N undecaethylene glycol Chemical compound OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO PSVXZQVXSXSQRO-UHFFFAOYSA-N 0.000 description 1
- 241001430294 unidentified retrovirus Species 0.000 description 1
- 229940044950 vaginal gel Drugs 0.000 description 1
- 239000000029 vaginal gel Substances 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 239000012873 virucide Substances 0.000 description 1
- 238000003260 vortexing Methods 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 201000000752 white piedra Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/08—Ethers or acetals acyclic, e.g. paraformaldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Reproductive Health (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Gynecology & Obstetrics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- AIDS & HIV (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IS4386 | 1996-11-14 | ||
| IS4386 | 1996-11-14 | ||
| PCT/DK1997/000524 WO1998020872A1 (en) | 1996-11-14 | 1997-11-14 | Topical formulations containing as a therapeutic active agent fatty acids or fatty alcohols or monoglyceride derivatives thereof for treating of mucosa infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2271843A1 true CA2271843A1 (en) | 1998-05-22 |
Family
ID=36699955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002271843A Abandoned CA2271843A1 (en) | 1996-11-14 | 1997-11-14 | Topical formulations containing as a therapeutic active agent fatty acids or fatty alcohols or monoglyceride derivatives thereof for treating of mucosa infections |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6596763B1 (https=) |
| EP (1) | EP0941087B1 (https=) |
| JP (1) | JP2001504461A (https=) |
| AP (1) | AP1209A (https=) |
| AT (1) | ATE442844T1 (https=) |
| AU (1) | AU729546B2 (https=) |
| CA (1) | CA2271843A1 (https=) |
| DE (1) | DE69739583D1 (https=) |
| IS (1) | IS5051A (https=) |
| WO (1) | WO1998020872A1 (https=) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19648545B4 (de) † | 1996-11-25 | 2009-05-07 | Ceramtec Ag | Monolithischer Vielschichtaktor mit Außenelektroden |
| IL133608A0 (en) * | 1997-06-20 | 2001-04-30 | Eggers Sabine | A protective composition for inhibiting bacterial, viral and fungal growth on the skin and use thereof |
| US6096332A (en) * | 1998-06-30 | 2000-08-01 | Mcneil-Ppc, Inc. | Adding pharmaceutically active compounds to substrates |
| RU2186563C2 (ru) * | 2000-02-25 | 2002-08-10 | Государственное унитарное предприятие Тихоокеанский научно-исследовательский рыбохозяйственный центр | Средство для лечения ожоговой раны |
| IL137559A (en) * | 2000-07-27 | 2006-12-31 | Amnon Sintov | A system for administering drugs through the skin |
| WO2002045695A2 (en) * | 2000-12-05 | 2002-06-13 | Alexander Macgregor | Hydrostatic delivery system for controlled delivery of agent |
| DE10156794B4 (de) * | 2001-11-19 | 2006-05-18 | Medigene Ag | Arzneimittel zur Behandlung von Warzen |
| MXPA04004532A (es) * | 2001-11-19 | 2004-08-11 | Medigene Ag | Medicamento para el tratamiento de enfermedades tumorales y virales de la piel. |
| US20050032896A1 (en) * | 2002-06-21 | 2005-02-10 | Liisa Neumann | Use of synthetic retinoic acid in form of 13-cis vitamin A for treatment of autism |
| US20050095281A1 (en) * | 2003-03-14 | 2005-05-05 | Optime Therapeutics, Inc. | Liposomal formulations and methods of use |
| ES2237298B1 (es) | 2003-07-16 | 2006-11-01 | Italfarmaco, S.A. | Formulaciones mucoadhesivas semisolidas. |
| GB0317999D0 (en) * | 2003-07-31 | 2003-09-03 | Univ Liege | Improvements in or relating to drug delivery systems |
| US20050058673A1 (en) | 2003-09-09 | 2005-03-17 | 3M Innovative Properties Company | Antimicrobial compositions and methods |
| CA2538119C (en) * | 2003-09-09 | 2013-05-14 | 3M Innovative Properties Company | Concentrated antimicrobial compositions and methods |
| US7910138B2 (en) | 2003-10-09 | 2011-03-22 | Medigene Ag | Use of a polyphenol for the treatment of a cancerous or precancerous lesion of the skin |
| US20050079235A1 (en) * | 2003-10-09 | 2005-04-14 | Eggert Stockfleth | Use of a polyphenol for the treatment of actinic keratosis |
| US20050215634A1 (en) * | 2003-11-11 | 2005-09-29 | Schlievert Patrick M | Regulation of cell membrane-mediated effects |
| US8796332B2 (en) * | 2004-08-03 | 2014-08-05 | Regents Of The University Of Minnesota | Compositions and methods for controlling infections |
| CA2578404A1 (en) * | 2004-08-23 | 2006-03-02 | Auckland Uniservices Limited | Gastric therapies and compositions therefor |
| US8535709B2 (en) * | 2004-12-13 | 2013-09-17 | Southeastern Medical Technologies, Llc | Agents for controlling biological fluids and methods of use thereof |
| ES2411054T3 (es) * | 2004-12-17 | 2013-07-04 | Halldor Thormar | Emulsiones antibacterianas concentradas estables de monocaprina en agua |
| MX2007010904A (es) * | 2005-03-10 | 2007-12-05 | 3M Innovative Properties Co | Panuelo para mascota antimicrobiano. |
| WO2006099325A2 (en) | 2005-03-10 | 2006-09-21 | 3M Innovative Properties Company | Methods of treating ear infections |
| US20060229364A1 (en) * | 2005-03-10 | 2006-10-12 | 3M Innovative Properties Company | Antiviral compositions and methods of use |
| BRPI0608691A2 (pt) | 2005-03-10 | 2010-12-07 | 3M Innovative Properties Company | composição antimicrobiana, e, métodos para matar ou inativar microorganismos em tecido da mucosa de um mamìfero, para tratar uma lesão ou ferimento infectado, para descolonização de microorganismos, para proporcionar eficácia antimicrobiana residual sobre uma superfìcie e para tratar uma condição |
| BRPI0608690B8 (pt) | 2005-03-10 | 2021-05-25 | 3M Innovative Properties Co | uso de uma composição antimicrobiana |
| US20080075793A1 (en) * | 2006-09-21 | 2008-03-27 | Dunshee Wayne K | Antiviral compositions and methods of use |
| EP2060192B9 (en) * | 2007-10-17 | 2016-05-04 | Rudolf Wild GmbH & Co. KG | Composition comprising lemon balm extracts |
| JP2009155257A (ja) * | 2007-12-26 | 2009-07-16 | Taiyo Corp | 抗菌剤及びそれを含有する口腔用組成物並びに飲食品 |
| ES2344673B1 (es) | 2008-08-07 | 2011-05-03 | Italfarmaco, S.A. | Uso de estriol en la preparacion de una formulacion farmaceutica parael tratamiento de atrofia vaginal en mujeres con riesgo de potologiatumoral. |
| ES2344675B1 (es) | 2008-12-19 | 2011-04-28 | Italfarmaco, S.A. | Uso de estriol en la preparacion de una formulacion farrmaceutica para el tratamiento de atrofia vaginal en mujeres con riesgo de patologiacardiovascular. |
| DE102009008094A1 (de) | 2009-02-09 | 2010-08-19 | Barnikol-Keuten, Doris, Dr. | In situ Haft-Gelbildende Zubereitungen, insbesondere zur topischen Anwendung auf befeuchtete Haut/Schleimhaut |
| UA104899C2 (uk) | 2009-08-06 | 2014-03-25 | Анітокс Корпорейшн | Консервант для води та корму |
| CN106913902A (zh) | 2009-11-09 | 2017-07-04 | 聚光灯技术合伙有限责任公司 | 多糖基水凝胶 |
| CN102695501A (zh) | 2009-11-09 | 2012-09-26 | 聚光灯技术合伙有限责任公司 | 碎裂水凝胶 |
| US12075777B2 (en) | 2010-08-27 | 2024-09-03 | Anitox Corporation | Antimicrobial formulation |
| CN103119144B (zh) * | 2010-09-14 | 2014-08-27 | 日油株式会社 | 一种抗菌洗涤剂组合物 |
| JP5749915B2 (ja) * | 2010-11-02 | 2015-07-15 | 花王株式会社 | オートインデューサー−２阻害剤 |
| WO2012078155A1 (en) * | 2010-12-09 | 2012-06-14 | The Research Foundation Of State University Of New York | Nitric oxide and its biomedical significance |
| US9055745B2 (en) | 2011-04-13 | 2015-06-16 | Natureza, Inc. | Compositions for internal and external insecticides, ovicides, repellents and wound healing |
| PT2768539T (pt) | 2011-10-20 | 2017-03-13 | Anitox Corp | Formulações antimicrobianas com ácido pelargónico |
| KR20140097253A (ko) | 2011-11-30 | 2014-08-06 | 아니톡스 코포레이션 | 알데히드, 유기산 및 유기산 에스테르의 항미생물성 혼합물 |
| DK3471541T3 (da) * | 2016-06-20 | 2021-08-09 | Capretto Ehf | Synergistiske virkninger, der forøger de antimikrobielle virkninger af lipider |
| CA3030408A1 (en) * | 2016-07-11 | 2018-01-18 | Hennepin Life Sciences, Llc | Compositions for sexually transmitted diseases |
| JP6754030B2 (ja) * | 2017-04-20 | 2020-09-09 | マイクロアルジェコーポレーション株式会社 | モノアシルグリセロール、抗菌剤、及びモノアシルグリセロールの製造方法 |
| CN114302707A (zh) | 2019-06-14 | 2022-04-08 | 普洛拉治疗公司 | 局部阿昔洛韦制剂及其用途 |
| US11572342B2 (en) | 2020-09-18 | 2023-02-07 | Niche Biopharmaceuticals LLC | Antimicrobial and antiviral sulfur containing glycerol monoester derivatives |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4406884A (en) | 1981-06-23 | 1983-09-27 | The Procter & Gamble Company | Topical antimicrobial composition |
| US4520132A (en) | 1982-09-27 | 1985-05-28 | Pennwalt Corporation | Use of undecylenic acid to treat herpes labialis |
| MX168518B (es) * | 1982-09-30 | 1993-05-27 | Union Carbide Corp | Composiciones de modelo que contienen resina epoxida curable |
| US5208257A (en) | 1986-04-21 | 1993-05-04 | Kabara Jon J | Topical antimicrobial pharmaceutical compositions and methods |
| US5434182A (en) * | 1987-12-31 | 1995-07-18 | Isaacs; Charles E. | Antibacterial fatty acid compositions |
| US5342625A (en) | 1988-09-16 | 1994-08-30 | Sandoz Ltd. | Pharmaceutical compositions comprising cyclosporins |
| NZ250714A (en) * | 1990-10-30 | 1996-05-28 | Mcneil Ppc Inc | Liquid composition comprising esters of higher fatty acids for use as a vaginal douche and to prevent toxic shock toxin production |
| IL104283A (en) | 1992-12-30 | 1996-12-05 | Agis Ind 1983 Ltd | Non-emulsion antiviral topical pharmaceutical composition comprising acyclovir an aqueous gel agent and an alkali oleate |
| IL110380A0 (en) | 1994-07-20 | 1994-10-21 | Agis Ind 1983 Ltd | Antiviral topical pharmaceutical compositions |
| CA2273960C (en) | 1996-09-17 | 2003-12-30 | Avanir Pharmaceuticals | Viral inhibition by long-chain alcohols, alkanes, fatty acids and amides |
-
1997
- 1997-11-14 DE DE69739583T patent/DE69739583D1/de not_active Expired - Lifetime
- 1997-11-14 AU AU49411/97A patent/AU729546B2/en not_active Ceased
- 1997-11-14 CA CA002271843A patent/CA2271843A1/en not_active Abandoned
- 1997-11-14 AP APAP/P/1999/001551A patent/AP1209A/en active
- 1997-11-14 US US09/297,921 patent/US6596763B1/en not_active Expired - Fee Related
- 1997-11-14 WO PCT/DK1997/000524 patent/WO1998020872A1/en not_active Ceased
- 1997-11-14 JP JP52206398A patent/JP2001504461A/ja not_active Ceased
- 1997-11-14 AT AT97912073T patent/ATE442844T1/de not_active IP Right Cessation
- 1997-11-14 EP EP97912073A patent/EP0941087B1/en not_active Expired - Lifetime
-
1999
- 1999-05-12 IS IS5051A patent/IS5051A/is unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0941087A1 (en) | 1999-09-15 |
| US6596763B1 (en) | 2003-07-22 |
| IS5051A (is) | 1999-05-12 |
| DE69739583D1 (de) | 2009-10-29 |
| ATE442844T1 (de) | 2009-10-15 |
| EP0941087B1 (en) | 2009-09-16 |
| AU729546B2 (en) | 2001-02-01 |
| JP2001504461A (ja) | 2001-04-03 |
| WO1998020872A1 (en) | 1998-05-22 |
| AP1209A (en) | 2003-09-30 |
| AU4941197A (en) | 1998-06-03 |
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| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |