CA2267657A1 - Derives hydroxyphenyliques ayant des proprietes inhibitrices de vih-integrase - Google Patents

Derives hydroxyphenyliques ayant des proprietes inhibitrices de vih-integrase Download PDF

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Publication number
CA2267657A1
CA2267657A1 CA 2267657 CA2267657A CA2267657A1 CA 2267657 A1 CA2267657 A1 CA 2267657A1 CA 2267657 CA2267657 CA 2267657 CA 2267657 A CA2267657 A CA 2267657A CA 2267657 A1 CA2267657 A1 CA 2267657A1
Authority
CA
Canada
Prior art keywords
group
dopamine
formula
compound
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2267657
Other languages
English (en)
Inventor
Sauve Gilles
Jocelyn Yelle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacor Inc
Original Assignee
Sauve Gilles
Jocelyn Yelle
Pharmacor Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sauve Gilles, Jocelyn Yelle, Pharmacor Inc. filed Critical Sauve Gilles
Priority to CA 2267657 priority Critical patent/CA2267657A1/fr
Priority to AU35461/00A priority patent/AU3546100A/en
Priority to PCT/CA2000/000327 priority patent/WO2000059867A1/fr
Priority to CA002302144A priority patent/CA2302144A1/fr
Priority to EP00913980A priority patent/EP1165492A1/fr
Publication of CA2267657A1 publication Critical patent/CA2267657A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA 2267657 1999-03-30 1999-03-30 Derives hydroxyphenyliques ayant des proprietes inhibitrices de vih-integrase Abandoned CA2267657A1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA 2267657 CA2267657A1 (fr) 1999-03-30 1999-03-30 Derives hydroxyphenyliques ayant des proprietes inhibitrices de vih-integrase
AU35461/00A AU3546100A (en) 1999-03-30 2000-03-27 Hydroxyphenyl derivatives with hiv integrase inhibitory properties
PCT/CA2000/000327 WO2000059867A1 (fr) 1999-03-30 2000-03-27 Derives d'hydroxyphenyle possedant des proprietes inhibitrices de l'integrase du vih
CA002302144A CA2302144A1 (fr) 1999-03-30 2000-03-27 Derives hydroxyphenyliques ayant des proprietes inhibitrices de vih-integrase
EP00913980A EP1165492A1 (fr) 1999-03-30 2000-03-27 Derives d'hydroxyphenyle possedant des proprietes inhibitrices de l'integrase du vih

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA 2267657 CA2267657A1 (fr) 1999-03-30 1999-03-30 Derives hydroxyphenyliques ayant des proprietes inhibitrices de vih-integrase

Publications (1)

Publication Number Publication Date
CA2267657A1 true CA2267657A1 (fr) 2000-09-30

Family

ID=29588663

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2267657 Abandoned CA2267657A1 (fr) 1999-03-30 1999-03-30 Derives hydroxyphenyliques ayant des proprietes inhibitrices de vih-integrase

Country Status (1)

Country Link
CA (1) CA2267657A1 (fr)

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Legal Events

Date Code Title Description
FZDE Dead