CA2302144A1 - Derives hydroxyphenyliques ayant des proprietes inhibitrices de vih-integrase - Google Patents

Derives hydroxyphenyliques ayant des proprietes inhibitrices de vih-integrase Download PDF

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Publication number
CA2302144A1
CA2302144A1 CA002302144A CA2302144A CA2302144A1 CA 2302144 A1 CA2302144 A1 CA 2302144A1 CA 002302144 A CA002302144 A CA 002302144A CA 2302144 A CA2302144 A CA 2302144A CA 2302144 A1 CA2302144 A1 CA 2302144A1
Authority
CA
Canada
Prior art keywords
formula
group
compound
dopamine
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002302144A
Other languages
English (en)
Inventor
Jocelyn Yelle
Gilles Sauve
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacor Inc
Original Assignee
Jocelyn Yelle
Gilles Sauve
Pharmacor Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA 2267657 external-priority patent/CA2267657A1/fr
Application filed by Jocelyn Yelle, Gilles Sauve, Pharmacor Inc. filed Critical Jocelyn Yelle
Priority to CA002302144A priority Critical patent/CA2302144A1/fr
Publication of CA2302144A1 publication Critical patent/CA2302144A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
CA002302144A 1999-03-30 2000-03-27 Derives hydroxyphenyliques ayant des proprietes inhibitrices de vih-integrase Abandoned CA2302144A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002302144A CA2302144A1 (fr) 1999-03-30 2000-03-27 Derives hydroxyphenyliques ayant des proprietes inhibitrices de vih-integrase

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA 2267657 CA2267657A1 (fr) 1999-03-30 1999-03-30 Derives hydroxyphenyliques ayant des proprietes inhibitrices de vih-integrase
CA2,267,657 1999-03-30
CA002302144A CA2302144A1 (fr) 1999-03-30 2000-03-27 Derives hydroxyphenyliques ayant des proprietes inhibitrices de vih-integrase

Publications (1)

Publication Number Publication Date
CA2302144A1 true CA2302144A1 (fr) 2000-09-30

Family

ID=25680872

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002302144A Abandoned CA2302144A1 (fr) 1999-03-30 2000-03-27 Derives hydroxyphenyliques ayant des proprietes inhibitrices de vih-integrase

Country Status (1)

Country Link
CA (1) CA2302144A1 (fr)

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Legal Events

Date Code Title Description
FZDE Dead