CA2267340A1 - Procede et compositions mettant en oeuvre des produits de fermentation a base de levure rouge - Google Patents
Procede et compositions mettant en oeuvre des produits de fermentation a base de levure rouge Download PDFInfo
- Publication number
- CA2267340A1 CA2267340A1 CA002267340A CA2267340A CA2267340A1 CA 2267340 A1 CA2267340 A1 CA 2267340A1 CA 002267340 A CA002267340 A CA 002267340A CA 2267340 A CA2267340 A CA 2267340A CA 2267340 A1 CA2267340 A1 CA 2267340A1
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- Prior art keywords
- red yeast
- monascus
- human
- yeast fermentation
- fermentation product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
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- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 description 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 1
- 201000001421 hyperglycemia Diseases 0.000 description 1
- 230000000999 hypotriglyceridemic effect Effects 0.000 description 1
- 239000003701 inert diluent Substances 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
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- 238000002955 isolation Methods 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 231100000861 limb weakness Toxicity 0.000 description 1
- 208000027905 limb weakness Diseases 0.000 description 1
- 229960004844 lovastatin Drugs 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
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- 238000005259 measurement Methods 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
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- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
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- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
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- GFSMXLMQRWMHON-UHFFFAOYSA-N monascin Natural products CCCCCC(=O)C1C2C=C3C=C(OC=C3C(=O)C2(C)OC1=O)C=CC GFSMXLMQRWMHON-UHFFFAOYSA-N 0.000 description 1
- GIKQHOXMDCDAPT-UHFFFAOYSA-N monascusone B Natural products CC=CC1=CC2=C(CO1)C(=O)C3(C)OC(=O)C(C3C2)C(=O)C GIKQHOXMDCDAPT-UHFFFAOYSA-N 0.000 description 1
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- 239000003921 oil Substances 0.000 description 1
- 229940127234 oral contraceptive Drugs 0.000 description 1
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- 239000003960 organic solvent Substances 0.000 description 1
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- 239000002245 particle Substances 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 229950000688 phenothiazine Drugs 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000003784 poor nutrition Nutrition 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 229920001592 potato starch Polymers 0.000 description 1
- 239000000955 prescription drug Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 1
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical class CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000001054 red pigment Substances 0.000 description 1
- 235000021067 refined food Nutrition 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000000518 rheometry Methods 0.000 description 1
- 235000019991 rice wine Nutrition 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 239000004460 silage Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 229940079832 sodium starch glycolate Drugs 0.000 description 1
- 239000008109 sodium starch glycolate Substances 0.000 description 1
- 229920003109 sodium starch glycolate Polymers 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
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- 239000007858 starting material Substances 0.000 description 1
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- 239000000375 suspending agent Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
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- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- 231100000041 toxicology testing Toxicity 0.000 description 1
- 238000009603 uroscopy Methods 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
- 239000001052 yellow pigment Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/145—Fungal isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Heart & Thoracic Surgery (AREA)
- Botany (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Microbiology (AREA)
- Diabetes (AREA)
- Food Science & Technology (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Nutrition Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Polymers & Plastics (AREA)
Abstract
On décrit des procédés et compositions mettant en oeuvre des produits de fermentation à base de levure rouge, que l'on peut utiliser en tant que compléments diététiques naturels et/ou médicaments destinés au traitement ou à la prévention de l'hyperlipidémie et des états et symptômes associés, tels que les maladies cardio-vasculaires et cérébro-vasculaires, le diabète, l'hypertension, l'obésité, la respiration asthénique, les maux de tête chroniques, les douleurs thoraciques et l'oppression, l'oedème et le gonflement des membres, la perte d'appétit et les expectorations importantes. Ces procédés et compositions sont efficaces pour abaisser les taux à la fois du cholestérol et des triglycérides sériques, et on peut les utiliser pour maintenir une bonne santé cardio-vasculaire. L'invention concerne également des souches de champignon Monascus, lesquelles donnent des produits de fermentation possédant les activités biologiques voulues.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72054896A | 1996-09-30 | 1996-09-30 | |
| US08/720,548 | 1996-09-30 | ||
| PCT/US1997/017574 WO1998014177A1 (fr) | 1996-09-30 | 1997-09-29 | Procede et compositions mettant en oeuvre des produits de fermentation a base de levure rouge |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2267340A1 true CA2267340A1 (fr) | 1998-04-09 |
Family
ID=24894390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002267340A Abandoned CA2267340A1 (fr) | 1996-09-30 | 1997-09-29 | Procede et compositions mettant en oeuvre des produits de fermentation a base de levure rouge |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0932395A1 (fr) |
| JP (1) | JP2001501621A (fr) |
| KR (1) | KR20000048765A (fr) |
| AU (1) | AU4658797A (fr) |
| BR (1) | BR9712168A (fr) |
| CA (1) | CA2267340A1 (fr) |
| HU (1) | HUP9904650A2 (fr) |
| IL (1) | IL129216A0 (fr) |
| WO (1) | WO1998014177A1 (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6436406B1 (en) | 2000-06-15 | 2002-08-20 | A. Glenn Braswell | Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides and atherosclerosis |
| KR100426880B1 (ko) * | 2002-02-04 | 2004-04-13 | 학교법인 영광학원 | 모나스쿠스 피로수스를 이용한 적색 메주색소의 제조방법 |
| KR20020093147A (ko) * | 2002-05-30 | 2002-12-13 | 지니스생명공학 주식회사 | 성인병 예방 및 치료 보조제 |
| CN1812801A (zh) * | 2003-06-24 | 2006-08-02 | 大塚制药株式会社 | 降低血清尿酸水平的组合物 |
| US20100119600A1 (en) * | 2007-06-01 | 2010-05-13 | Joar Opheim | Substances for reducing occurrence of major cardiac events comprising red yeast rice extract and omega-3 polyunsaturated fatty acid or derivative thereof |
| TW201038205A (en) * | 2009-04-29 | 2010-11-01 | Sunway Biotech Co Ltd | The compositions of Monascus fermented products with a function that reduces body fatness formation and the method for manufacturing the same |
| JP2010273569A (ja) * | 2009-05-26 | 2010-12-09 | Wasaburo Sato | メタボリックシンドローム改善作用を有する飲料及びサプリメント |
| JP5912361B2 (ja) * | 2011-09-16 | 2016-04-27 | 晨暉生物科技股▲分▼有限公司 | 血液脂質を引き下げ、ｈｄｌコレステロールを引き上げることができる混合物とその製造方法 |
| SG11201403618PA (en) | 2011-12-26 | 2014-09-26 | Univ Beijing Peking Wbl Biotech Co Ltd | A sterol derivative and preparation method and uses thereof |
| CN113171316B (zh) * | 2021-04-23 | 2022-06-14 | 科丝美诗(中国)化妆品有限公司 | 一种修复、缓解皮肤刺激化妆品及制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56150037A (en) * | 1980-04-22 | 1981-11-20 | Sankyo Co Ltd | Hydronaphthalene compound |
| JP3168298B2 (ja) * | 1993-02-05 | 2001-05-21 | 有限会社フジ・バイオ研究所 | 紅麹を使用した酒精飲料の製造法 |
-
1997
- 1997-09-29 IL IL12921697A patent/IL129216A0/xx unknown
- 1997-09-29 AU AU46587/97A patent/AU4658797A/en not_active Abandoned
- 1997-09-29 WO PCT/US1997/017574 patent/WO1998014177A1/fr not_active Application Discontinuation
- 1997-09-29 EP EP97945365A patent/EP0932395A1/fr not_active Withdrawn
- 1997-09-29 JP JP10516787A patent/JP2001501621A/ja active Pending
- 1997-09-29 KR KR1019990702751A patent/KR20000048765A/ko not_active Application Discontinuation
- 1997-09-29 BR BR9712168-1A patent/BR9712168A/pt unknown
- 1997-09-29 CA CA002267340A patent/CA2267340A1/fr not_active Abandoned
- 1997-09-29 HU HU9904650A patent/HUP9904650A2/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUP9904650A2 (hu) | 2000-05-28 |
| JP2001501621A (ja) | 2001-02-06 |
| KR20000048765A (ko) | 2000-07-25 |
| IL129216A0 (en) | 2000-02-17 |
| AU4658797A (en) | 1998-04-24 |
| BR9712168A (pt) | 2000-01-18 |
| EP0932395A1 (fr) | 1999-08-04 |
| WO1998014177A1 (fr) | 1998-04-09 |
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