SG11201403618PA - A sterol derivative and preparation method and uses thereof - Google Patents

A sterol derivative and preparation method and uses thereof

Info

Publication number
SG11201403618PA
SG11201403618PA SG11201403618PA SG11201403618PA SG11201403618PA SG 11201403618P A SG11201403618P A SG 11201403618PA SG 11201403618P A SG11201403618P A SG 11201403618PA SG 11201403618P A SG11201403618P A SG 11201403618PA SG 11201403618P A SG11201403618P A SG 11201403618PA
Authority
SG
Singapore
Prior art keywords
preparation
sterol derivative
sterol
derivative
Prior art date
Application number
SG11201403618PA
Inventor
Zhenwen Duan
Shuren Guo
Xuemei Li
Original Assignee
Univ Beijing Peking Wbl Biotech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN201110442009.4A external-priority patent/CN103169713B/en
Priority claimed from CN201110441993.2A external-priority patent/CN103172693B/en
Priority claimed from CN201210015475.9A external-priority patent/CN103211822B/en
Application filed by Univ Beijing Peking Wbl Biotech Co Ltd filed Critical Univ Beijing Peking Wbl Biotech Co Ltd
Publication of SG11201403618PA publication Critical patent/SG11201403618PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG11201403618PA 2011-12-26 2012-12-25 A sterol derivative and preparation method and uses thereof SG11201403618PA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN201110442009.4A CN103169713B (en) 2011-12-26 2011-12-26 A kind of sterol derivative is preparing the purposes in cancer therapy drug
CN201110441993.2A CN103172693B (en) 2011-12-26 2011-12-26 A kind of sterol derivative, Preparation Method And The Use
CN201210015475.9A CN103211822B (en) 2012-01-18 2012-01-18 A kind of purposes of the suppression lipase of sterol derivative
PCT/CN2012/087360 WO2013097681A1 (en) 2011-12-26 2012-12-25 Sterols derivative, and preparation method and purpose thereof

Publications (1)

Publication Number Publication Date
SG11201403618PA true SG11201403618PA (en) 2014-09-26

Family

ID=48696334

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201403618PA SG11201403618PA (en) 2011-12-26 2012-12-25 A sterol derivative and preparation method and uses thereof

Country Status (9)

Country Link
US (6) US10889612B2 (en)
EP (1) EP2799444B1 (en)
CN (1) CN104024270B (en)
ES (1) ES2666459T3 (en)
HK (1) HK1198539A1 (en)
MY (1) MY172011A (en)
SG (1) SG11201403618PA (en)
TW (1) TWI518094B (en)
WO (1) WO2013097681A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2666459T3 (en) 2011-12-26 2018-05-04 Beijing Peking University Wbl Biotech Co., Ltd Sterol derivative, preparation procedure and purpose thereof
CN109371053B (en) * 2018-12-24 2021-08-06 江西科技师范大学 Construction method of monascus pigment producing strain

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046022A (en) * 1996-09-30 2000-04-04 Peking University Methods and compositions employing red rice fermentation products
US7238348B2 (en) * 1996-09-30 2007-07-03 Beijing Peking University Wbl Corporation Ltd. Method of treatment of osteoporosis with compositions of red rice fermentation products
AU4658797A (en) * 1996-09-30 1998-04-24 Peking University Methods and compositions employing red yeast fermentation products
US6020383A (en) * 1999-01-11 2000-02-01 Eastman Chemicals Company Method for reducing blood cholesterol and/or blood triglycerides
US6436406B1 (en) * 2000-06-15 2002-08-20 A. Glenn Braswell Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides and atherosclerosis
CN1982327B (en) 2005-12-13 2010-05-05 北京师范大学 Phytosterin compound and its use
CN101104003A (en) 2006-07-11 2008-01-16 北京北大维信生物科技有限公司 Xuezhikang purpose-made monascus anti-cancer new use
CN101313919B (en) * 2007-05-31 2012-08-08 北京北大维信生物科技有限公司 Rice fermented with red yeast extract, preparation method and quality detection method thereof
US20090004290A1 (en) 2007-06-30 2009-01-01 Voelker Kirk G Red yeast rice compound for cancer chemoprevention
CN101469014B (en) 2007-12-27 2011-06-15 北京北大维信生物科技有限公司 Novel compound and separation method thereof
US7993666B2 (en) 2008-04-18 2011-08-09 Warsaw Orthopedic, Inc. Methods and compositions for treating pain comprising a statin
CN101942003A (en) * 2009-07-09 2011-01-12 北京北大维信生物科技有限公司 Compound and preparation method thereof
WO2011003284A1 (en) 2009-07-09 2011-01-13 北京北大维信生物科技有限公司 Compound and preparation method and use thereof
CN102617533B (en) * 2011-02-01 2014-08-27 北京北大维信生物科技有限公司 Compound separated from red yeast rice, its preparation method and application
CN103169713B (en) * 2011-12-26 2015-07-29 北京北大维信生物科技有限公司 A kind of sterol derivative is preparing the purposes in cancer therapy drug
CN103211822B (en) * 2012-01-18 2017-09-22 北京北大维信生物科技有限公司 A kind of purposes of the suppression lipase of sterol derivative
CN103172693B (en) * 2011-12-26 2016-01-27 北京北大维信生物科技有限公司 A kind of sterol derivative, Preparation Method And The Use
ES2666459T3 (en) * 2011-12-26 2018-05-04 Beijing Peking University Wbl Biotech Co., Ltd Sterol derivative, preparation procedure and purpose thereof
CN104159910B (en) * 2012-02-02 2017-02-15 北京北大维信生物科技有限公司 Sterol derivative, preparation method therefor and use thereof
CN105985244A (en) * 2015-02-04 2016-10-05 北京北大维信生物科技有限公司 Compound as well as separation method, synthetic method and application thereof

Also Published As

Publication number Publication date
EP2799444A1 (en) 2014-11-05
US20220389051A1 (en) 2022-12-08
US20210047364A1 (en) 2021-02-18
US20220402967A1 (en) 2022-12-22
US20210024570A1 (en) 2021-01-28
US10889612B2 (en) 2021-01-12
US11634454B2 (en) 2023-04-25
TW201345920A (en) 2013-11-16
EP2799444B1 (en) 2018-01-24
CN104024270A (en) 2014-09-03
WO2013097681A1 (en) 2013-07-04
TWI518094B (en) 2016-01-21
US11845774B2 (en) 2023-12-19
US20150031657A1 (en) 2015-01-29
MY172011A (en) 2019-11-11
ES2666459T3 (en) 2018-05-04
CN104024270B (en) 2016-07-06
US11845775B2 (en) 2023-12-19
US20220387453A1 (en) 2022-12-08
EP2799444A4 (en) 2015-07-01
HK1198539A1 (en) 2015-05-15

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