CA2248139C - Methods of alleviating neuropathic pain using prosaposin-derived peptides - Google Patents
Methods of alleviating neuropathic pain using prosaposin-derived peptides Download PDFInfo
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- CA2248139C CA2248139C CA002248139A CA2248139A CA2248139C CA 2248139 C CA2248139 C CA 2248139C CA 002248139 A CA002248139 A CA 002248139A CA 2248139 A CA2248139 A CA 2248139A CA 2248139 C CA2248139 C CA 2248139C
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- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/611,307 | 1996-03-05 | ||
| US08/611,307 US6271196B1 (en) | 1996-03-05 | 1996-03-05 | Methods of alleviating neuropathic pain using prosaposin-derived peptides |
| PCT/US1997/004143 WO1997032895A1 (en) | 1996-03-05 | 1997-03-05 | Methods of alleviating neuropathic pain using prosaposin-derived peptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2248139A1 CA2248139A1 (en) | 1997-09-12 |
| CA2248139C true CA2248139C (en) | 2004-05-18 |
Family
ID=24448513
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002248139A Expired - Fee Related CA2248139C (en) | 1996-03-05 | 1997-03-05 | Methods of alleviating neuropathic pain using prosaposin-derived peptides |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US6271196B1 (OSRAM) |
| EP (1) | EP0929569B1 (OSRAM) |
| JP (1) | JP4138006B2 (OSRAM) |
| KR (1) | KR100507715B1 (OSRAM) |
| AT (1) | ATE340187T1 (OSRAM) |
| AU (1) | AU734566B2 (OSRAM) |
| CA (1) | CA2248139C (OSRAM) |
| CZ (1) | CZ297384B6 (OSRAM) |
| DE (1) | DE69736712T2 (OSRAM) |
| IL (1) | IL126082A0 (OSRAM) |
| NO (1) | NO984093L (OSRAM) |
| NZ (1) | NZ331757A (OSRAM) |
| PL (1) | PL187917B1 (OSRAM) |
| RU (2) | RU2266129C2 (OSRAM) |
| SK (1) | SK122898A3 (OSRAM) |
| WO (1) | WO1997032895A1 (OSRAM) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5571787A (en) * | 1993-07-30 | 1996-11-05 | Myelos Corporation | Prosaposin as a neurotrophic factor |
| US6849602B1 (en) * | 1996-03-05 | 2005-02-01 | The Regents Of The University Of California | Compositions for alleviating neuropathic pain with prosaposin receptor agonists |
| CA2282827A1 (en) * | 1997-03-05 | 1998-09-11 | The Regents Of The University Of California | Method of alleviating neuropathic pain |
| JP2001524944A (ja) * | 1997-03-05 | 2001-12-04 | ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア | 神経障害性疼痛の緩和方法 |
| CA2284105A1 (en) * | 1997-03-24 | 1998-10-01 | John S. O'brien | Synthetic saposin c-derived neurotrophic peptides |
| US6458357B1 (en) * | 1997-09-09 | 2002-10-01 | Myelos Corporation | Retro-inverso neurotrophic and analgesic peptides |
| EP1011709A4 (en) * | 1997-09-09 | 2003-06-18 | Univ California | INHIBITION OF APOPTOSIS USING PROSAPOSIN RECEPTOR AGONISTS |
| CA2341810A1 (en) * | 1998-08-28 | 2000-03-09 | Myelos Corporation | Cyclic prosaposin-derived peptides and uses thereof |
| US20020028783A1 (en) * | 1999-09-09 | 2002-03-07 | O'brien John S. | Method of stimulating prosaposin receptor activity |
| USRE45976E1 (en) * | 1999-02-24 | 2016-04-19 | Tact Ip, Llc | Methods of inhibiting the action of TNF for neurological conditions by administering etanercept intrathecally |
| JP2002544120A (ja) * | 1999-03-30 | 2002-12-24 | ミエロスコーポレーション | 逆・反転化プロサポシン由来ポリペプチドおよびその使用 |
| US7309687B1 (en) | 1999-04-13 | 2007-12-18 | The Kenneth S. Warren Institute, Inc. | Methods for treatment and prevention of neuromuscular and muscular conditions by peripherally administered erythropoietin |
| US7345019B1 (en) | 1999-04-13 | 2008-03-18 | The Kenneth S. Warren Institute, Inc. | Modulation of excitable tissue function by peripherally administered erythropoietin |
| JP4786843B2 (ja) * | 1999-06-16 | 2011-10-05 | マイアロス コーポレイション | インターロイキン−６から誘導されるレトロ−インベルソペプチド |
| US7109168B1 (en) | 2000-06-16 | 2006-09-19 | Myelos Corporation | Retro-inverso peptides derived from leukemia inhibitory factor |
| US7135461B1 (en) | 2000-06-16 | 2006-11-14 | Myelos Corporation | Retro-inverso peptides derived from interleukin-6 |
| CA2376394A1 (en) * | 1999-06-16 | 2000-12-21 | David E. Wright | Retro-inverso peptides derived from interleukin-3 |
| JP2003502341A (ja) * | 1999-06-16 | 2003-01-21 | マイアロス コーポレイション | 白血病阻害因子に由来するレトロ−インベルソなペプチド |
| US20040170955A1 (en) * | 2000-09-08 | 2004-09-02 | Wadih Arap | Human and mouse targeting peptides identified by phage display |
| US7420030B2 (en) * | 2000-09-08 | 2008-09-02 | The Board Of Regents Of The University Of Texas System | Aminopeptidase A (APA) targeting peptides for the treatment of cancer |
| US20050074747A1 (en) * | 2000-09-08 | 2005-04-07 | Wadih Arap | Biopanning and rapid analysis of selective interactive ligands (brasil) |
| US7452964B2 (en) | 2001-09-07 | 2008-11-18 | Board Of Regents, The University Of Texas System | Compositions and methods of use of targeting peptides against placenta and adipose tissues |
| US6531121B2 (en) | 2000-12-29 | 2003-03-11 | The Kenneth S. Warren Institute, Inc. | Protection and enhancement of erythropoietin-responsive cells, tissues and organs |
| US20060287240A1 (en) * | 2001-03-09 | 2006-12-21 | O'brien John S | Method of stimulating prosaposin receptor activity |
| EP1418932A4 (en) * | 2001-07-18 | 2006-03-15 | Univ Texas | ANTIANGIOGENIC CONDITION IN MICE AND PEOPLE WITH RETINAL PHOTOREEPEPTOR DEGENERATION |
| US7671010B2 (en) * | 2002-08-30 | 2010-03-02 | The Board Of Regents Of The University Of Texas System | Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer |
| US20040048243A1 (en) * | 2001-09-07 | 2004-03-11 | Wadih Arap | Methods and compositions for in vitro targeting |
| US8507445B2 (en) * | 2001-09-07 | 2013-08-13 | Board Of Regents, The University Of Texas System | Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer |
| US20040096089A1 (en) * | 2002-08-16 | 2004-05-20 | David Borsook | Non-invasive functional imaging of peripheral nervous system activation in humans and animals |
| US7166691B2 (en) * | 2002-12-20 | 2007-01-23 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Saposin C and receptors as targets for treatment of benign and malignant disorders |
| US20060275274A1 (en) * | 2003-03-26 | 2006-12-07 | Daria Onichtchouk | Use of saposin-related proteins for preventing and treating obesity, diabetes and/or metabolic syndrome |
| BRPI0409523A (pt) * | 2003-03-28 | 2006-04-18 | Acadia Pharm Inc | método para o tratamento da dor neuropática, método de identificação de um composto e composição farmacêutica |
| US7834147B2 (en) * | 2003-04-28 | 2010-11-16 | Childrens Hospital Medical Center | Saposin C-DOPS: a novel anti-tumor agent |
| CN100366286C (zh) * | 2003-04-28 | 2008-02-06 | 常州南云科技有限公司 | Saposin C-DOPS:一种抗癌新药 |
| US9345745B2 (en) * | 2005-04-29 | 2016-05-24 | Bo Wang | Methods for treating inflammatory disorders and traumatic brain injury using stabilized non-hematopoietic EPO short peptides |
| EP1736481A1 (en) * | 2005-05-13 | 2006-12-27 | Charite Universitätsmedizin-Berlin | Erythropoietin variants |
| RU2317829C2 (ru) * | 2005-10-05 | 2008-02-27 | Федеральное государственное учреждение науки "Екатеринбургский медицинский научный центр профилактики и охраны здоровья рабочих промпредприятий" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека | Способ лечения мононевропатий верхних конечностей |
| US7964585B2 (en) * | 2006-03-14 | 2011-06-21 | Case Western Reserve University | Composition and method of treating peripheral neuropathy |
| RU2345786C2 (ru) * | 2007-02-27 | 2009-02-10 | Андрей Евгеньевич Кульчиков | Способ лечения непрерывно-прогредиентных дегенеративных и демиелинизирующих заболеваний |
| CN104689298A (zh) | 2008-01-22 | 2015-06-10 | 阿拉伊姆药品公司 | 用于预防和治疗组织损伤相关疾病和病症的组织保护肽和肽类似物 |
| RU2561582C2 (ru) * | 2010-11-19 | 2015-08-27 | Российская Федерация в лице Министерства промышленности и торговли Российской Федерации | Инъекционная лекарственная форма олигопептидного препарата для лечения рассеянного склероза и способ ее получения |
| US9327012B2 (en) * | 2011-02-23 | 2016-05-03 | Sapporo Medical University | Composition for treating, improving, or preventing pain |
| RU2669692C1 (ru) * | 2017-08-14 | 2018-10-15 | Павел Андреевич Канаев | Способ получения комплекса биологически активных пептидов обладающих нейротропной активностью |
| MX2020009829A (es) | 2018-03-23 | 2021-01-08 | Bexion Pharmaceuticals Inc | Composiciones farmaceuticas de saposina c y metodos para tratar el cancer. |
| RU2020131598A (ru) | 2018-03-29 | 2022-04-29 | Лэйтерал Ип Пти Лтд | Циклические пептиды и их применение |
| MX2023008177A (es) * | 2021-01-09 | 2023-08-30 | Bexion Pharmaceuticals Inc | Métodos para reducir la neuropatía y síntomas neuropáticos y para el tratamiento contra el cáncer. |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE108459T1 (de) | 1986-04-22 | 1994-07-15 | Salk Inst For Biological Studi | Antagonisten des fibroblasten-wachstumsfaktors. |
| DD298412A5 (de) * | 1989-04-28 | 1992-02-20 | ������@���Kk�� | Verfahren zur herstellung von polypeptiden, die geeignet sind als antagonisten exzitatorischer aminosaeure-neurotransmitter und/oder blocker der calciumkanaele |
| US5169764A (en) * | 1990-08-08 | 1992-12-08 | Regeneron Pharmaceuticals, Inc. | Multitrophic and multifunctional chimeric neurotrophic factors, and nucleic acids and plasmids encoding the chimeras |
| US5187151A (en) * | 1991-02-12 | 1993-02-16 | Genentech, Inc. | Use of binding protein with igf-i as an anabolic growth promoting agent |
| RU2007417C1 (ru) * | 1991-06-21 | 1994-02-15 | Российский государственный медицинский университет | Способ получения плацентарного протеина |
| WO1993015722A1 (en) | 1992-02-07 | 1993-08-19 | Syntex (Usa) Inc. | Controlled delivery of pharmaceuticals from preformed porous microparticles |
| US5534495A (en) * | 1993-05-25 | 1996-07-09 | Advanced Peptides And Biotechnology Sciences | Treatment of non-HIV neuropathic pain syndromes |
| US5571787A (en) | 1993-07-30 | 1996-11-05 | Myelos Corporation | Prosaposin as a neurotrophic factor |
| US5700909A (en) * | 1993-07-30 | 1997-12-23 | The Regents Of The University Of California | Prosaposin and cytokine-derived peptides |
| WO1995013823A1 (en) * | 1993-11-15 | 1995-05-26 | Celtrix Pharmaceuticals, Inc. | Method of treating neurological disorders |
| CA2282827A1 (en) * | 1997-03-05 | 1998-09-11 | The Regents Of The University Of California | Method of alleviating neuropathic pain |
| CA2284105A1 (en) * | 1997-03-24 | 1998-10-01 | John S. O'brien | Synthetic saposin c-derived neurotrophic peptides |
-
1996
- 1996-03-05 US US08/611,307 patent/US6271196B1/en not_active Expired - Fee Related
-
1997
- 1997-03-05 SK SK1228-98A patent/SK122898A3/sk unknown
- 1997-03-05 RU RU2003131695/14A patent/RU2266129C2/ru not_active IP Right Cessation
- 1997-03-05 PL PL32870197A patent/PL187917B1/pl not_active IP Right Cessation
- 1997-03-05 CZ CZ0283998A patent/CZ297384B6/cs not_active IP Right Cessation
- 1997-03-05 NZ NZ331757A patent/NZ331757A/en active IP Right Revival
- 1997-03-05 EP EP97916005A patent/EP0929569B1/en not_active Expired - Lifetime
- 1997-03-05 AT AT97916005T patent/ATE340187T1/de not_active IP Right Cessation
- 1997-03-05 IL IL12608297A patent/IL126082A0/xx unknown
- 1997-03-05 CA CA002248139A patent/CA2248139C/en not_active Expired - Fee Related
- 1997-03-05 AU AU23286/97A patent/AU734566B2/en not_active Ceased
- 1997-03-05 WO PCT/US1997/004143 patent/WO1997032895A1/en not_active Ceased
- 1997-03-05 KR KR1019980707151A patent/KR100507715B1/ko not_active Expired - Fee Related
- 1997-03-05 JP JP53205097A patent/JP4138006B2/ja not_active Expired - Fee Related
- 1997-03-05 RU RU98118091/04A patent/RU2223969C2/ru not_active IP Right Cessation
- 1997-03-05 DE DE69736712T patent/DE69736712T2/de not_active Expired - Fee Related
-
1998
- 1998-09-04 NO NO984093A patent/NO984093L/no not_active Application Discontinuation
-
1999
- 1999-01-15 US US09/231,159 patent/US6268347B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6268347B1 (en) | 2001-07-31 |
| AU734566B2 (en) | 2001-06-14 |
| DE69736712T2 (de) | 2007-09-13 |
| NO984093L (no) | 1998-11-04 |
| EP0929569A4 (en) | 2000-08-23 |
| SK122898A3 (en) | 2000-02-14 |
| DE69736712D1 (de) | 2006-11-02 |
| WO1997032895A1 (en) | 1997-09-12 |
| CA2248139A1 (en) | 1997-09-12 |
| NO984093D0 (no) | 1998-09-04 |
| RU2223969C2 (ru) | 2004-02-20 |
| EP0929569B1 (en) | 2006-09-20 |
| RU2003131695A (ru) | 2005-04-10 |
| KR100507715B1 (ko) | 2006-05-26 |
| AU2328697A (en) | 1997-09-22 |
| EP0929569A1 (en) | 1999-07-21 |
| JP2000506853A (ja) | 2000-06-06 |
| IL126082A0 (en) | 1999-05-09 |
| JP4138006B2 (ja) | 2008-08-20 |
| KR19990087686A (ko) | 1999-12-27 |
| US6271196B1 (en) | 2001-08-07 |
| NZ331757A (en) | 1999-10-28 |
| CZ297384B6 (cs) | 2006-11-15 |
| RU2266129C2 (ru) | 2005-12-20 |
| PL187917B1 (pl) | 2004-11-30 |
| CZ283998A3 (cs) | 1999-05-12 |
| PL328701A1 (en) | 1999-02-15 |
| ATE340187T1 (de) | 2006-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |