CA2238376C - Benzofuran carboxamides and sulphonamides - Google Patents
Benzofuran carboxamides and sulphonamides Download PDFInfo
- Publication number
- CA2238376C CA2238376C CA002238376A CA2238376A CA2238376C CA 2238376 C CA2238376 C CA 2238376C CA 002238376 A CA002238376 A CA 002238376A CA 2238376 A CA2238376 A CA 2238376A CA 2238376 C CA2238376 C CA 2238376C
- Authority
- CA
- Canada
- Prior art keywords
- alkyl
- methoxy
- compound
- benzofuransulphonamide
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9524832.4 | 1995-12-05 | ||
| GBGB9524832.4A GB9524832D0 (en) | 1995-12-05 | 1995-12-05 | Novel compounds |
| GBGB9610515.0A GB9610515D0 (en) | 1996-05-20 | 1996-05-20 | Novel compounds |
| GB9610515.0 | 1996-05-20 | ||
| GBGB9610712.3A GB9610712D0 (en) | 1995-12-05 | 1996-05-22 | Novel compounds |
| GB9610712.3 | 1996-05-22 | ||
| PCT/GB1996/003012 WO1997020833A1 (en) | 1995-12-05 | 1996-12-05 | Benzofuran carboxamides and sulphonamides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2238376A1 CA2238376A1 (en) | 1997-06-12 |
| CA2238376C true CA2238376C (en) | 2006-08-15 |
Family
ID=27268015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002238376A Expired - Fee Related CA2238376C (en) | 1995-12-05 | 1996-12-05 | Benzofuran carboxamides and sulphonamides |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5773467A (enExample) |
| EP (1) | EP0873331B1 (enExample) |
| JP (1) | JP2000501411A (enExample) |
| KR (1) | KR19990071894A (enExample) |
| CN (1) | CN1100773C (enExample) |
| AT (1) | ATE215540T1 (enExample) |
| AU (1) | AU697976B2 (enExample) |
| BR (1) | BR9611897A (enExample) |
| CA (1) | CA2238376C (enExample) |
| CZ (1) | CZ292443B6 (enExample) |
| DE (1) | DE69620458T2 (enExample) |
| ES (1) | ES2172695T3 (enExample) |
| HU (1) | HUP9903797A3 (enExample) |
| NO (1) | NO982570L (enExample) |
| PL (1) | PL327181A1 (enExample) |
| WO (1) | WO1997020833A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ371998A3 (cs) * | 1996-05-20 | 1999-03-17 | Darwin Discovery Limited | Benzofuranové karboxamidy a jejich terapeutické použití |
| EP0923568B9 (en) * | 1996-08-19 | 2003-08-13 | ALTANA Pharma AG | Novel benzofuran-4-carboxamides |
| JP3268236B2 (ja) | 1997-07-22 | 2002-03-25 | シャープ株式会社 | 電子写真感光体、及びビスヒドラゾン化合物およびその中間体、ならびにそれら化合物の製造方法 |
| ATE237612T1 (de) | 1997-10-01 | 2003-05-15 | Kyowa Hakko Kogyo Kk | Benzofuranderivate |
| AU1983599A (en) * | 1998-01-26 | 1999-08-09 | Kyowa Hakko Kogyo Co. Ltd. | Oxygenic heterocyclic compounds |
| JP2002502851A (ja) * | 1998-02-09 | 2002-01-29 | ダーウィン・ディスカバリー・リミテッド | ベンゾフラン−４−カルボキサミドとその治療的使用 |
| FR2778662B1 (fr) * | 1998-05-12 | 2000-06-16 | Adir | Nouveaux composes cycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| TW555759B (en) * | 1998-06-08 | 2003-10-01 | Darwin Discovery Ltd | Heterocyclic compounds and their therapeutic use |
| JP2002517495A (ja) * | 1998-06-10 | 2002-06-18 | ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | ホスホジエステラーゼ４の阻害剤としてのテトラヒドロフラニルオキシ置換基を有するベンズアミド |
| HRP20020158B1 (en) | 1999-08-21 | 2007-08-31 | Altana Pharma Ag | Action of synergistic combination |
| US7217722B2 (en) | 2000-02-01 | 2007-05-15 | Kirin Beer Kabushiki Kaisha | Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same |
| GB0011802D0 (en) * | 2000-05-16 | 2000-07-05 | Smithkline Beecham | Method for enhancing cognitive function |
| EP1624893A2 (en) | 2003-04-01 | 2006-02-15 | Applied Research Systems ARS Holding N.V. | Inhibitors of phosphodiesterases in infertility |
| FR2903106B1 (fr) * | 2006-07-03 | 2010-07-30 | Sanofi Aventis | Utilisations de 2-benzoyl-imidazopyridines en therapeutique |
| EP2196465A1 (en) | 2008-12-15 | 2010-06-16 | Almirall, S.A. | (3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors |
| AR074760A1 (es) * | 2008-12-18 | 2011-02-09 | Metabolex Inc | Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico. |
| EP2226323A1 (en) | 2009-02-27 | 2010-09-08 | Almirall, S.A. | New tetrahydropyrazolo[3,4-c]isoquinolin-5-amine derivatives |
| EP2380890A1 (en) | 2010-04-23 | 2011-10-26 | Almirall, S.A. | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors |
| EP2394998A1 (en) | 2010-05-31 | 2011-12-14 | Almirall, S.A. | 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl derivatives as PDE4 inhibitors |
| WO2012011314A1 (ja) | 2010-07-22 | 2012-01-26 | 扶桑薬品工業株式会社 | ベンゾフラノン化合物およびそれを含む医薬組成物 |
| EP3597186B1 (en) | 2015-01-05 | 2021-12-08 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Myc g-quadruplex stabilizing small molecules and their use |
| CN114149457B (zh) * | 2021-11-03 | 2024-04-12 | 湖北民族大学 | 一种苯并[c][1,2]氧杂硼戊环-1(3H)-醇类合物及其用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4666931A (en) * | 1984-12-29 | 1987-05-19 | Kaken Pharmaceutical Co., Ltd. | Benzofuran derivatives useful in treating diabetic complications |
| EP0685475B1 (en) * | 1994-05-31 | 1999-01-13 | Bayer Ag | Amino-benzofuryl-and thienyl-derivatives |
| DE59508773D1 (de) * | 1994-07-22 | 2000-11-09 | Byk Gulden Lomberg Chem Fab | Dihydrobenzofurane |
| CN1163493C (zh) * | 1995-05-19 | 2004-08-25 | 协和发酵工业株式会社 | 含氧杂环化合物 |
| CZ371998A3 (cs) * | 1996-05-20 | 1999-03-17 | Darwin Discovery Limited | Benzofuranové karboxamidy a jejich terapeutické použití |
-
1996
- 1996-12-05 AT AT96941138T patent/ATE215540T1/de not_active IP Right Cessation
- 1996-12-05 ES ES96941138T patent/ES2172695T3/es not_active Expired - Lifetime
- 1996-12-05 KR KR1019980704179A patent/KR19990071894A/ko not_active Ceased
- 1996-12-05 HU HU9903797A patent/HUP9903797A3/hu unknown
- 1996-12-05 WO PCT/GB1996/003012 patent/WO1997020833A1/en not_active Ceased
- 1996-12-05 JP JP9521090A patent/JP2000501411A/ja not_active Ceased
- 1996-12-05 DE DE69620458T patent/DE69620458T2/de not_active Expired - Fee Related
- 1996-12-05 AU AU10386/97A patent/AU697976B2/en not_active Ceased
- 1996-12-05 CN CN96198844A patent/CN1100773C/zh not_active Expired - Fee Related
- 1996-12-05 CA CA002238376A patent/CA2238376C/en not_active Expired - Fee Related
- 1996-12-05 BR BR9611897-0A patent/BR9611897A/pt active Search and Examination
- 1996-12-05 PL PL96327181A patent/PL327181A1/xx unknown
- 1996-12-05 CZ CZ19981714A patent/CZ292443B6/cs not_active IP Right Cessation
- 1996-12-05 US US08/761,102 patent/US5773467A/en not_active Expired - Fee Related
- 1996-12-05 EP EP96941138A patent/EP0873331B1/en not_active Expired - Lifetime
-
1998
- 1998-06-04 NO NO982570A patent/NO982570L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP9903797A3 (en) | 2001-08-28 |
| CA2238376A1 (en) | 1997-06-12 |
| JP2000501411A (ja) | 2000-02-08 |
| AU697976B2 (en) | 1998-10-22 |
| CZ292443B6 (cs) | 2003-09-17 |
| CN1100773C (zh) | 2003-02-05 |
| DE69620458T2 (de) | 2002-10-02 |
| DE69620458D1 (de) | 2002-05-08 |
| US5773467A (en) | 1998-06-30 |
| HUP9903797A2 (hu) | 2001-04-28 |
| NO982570L (no) | 1998-08-04 |
| CN1208411A (zh) | 1999-02-17 |
| ES2172695T3 (es) | 2002-10-01 |
| MX9804466A (es) | 1998-12-31 |
| KR19990071894A (ko) | 1999-09-27 |
| NO982570D0 (no) | 1998-06-04 |
| EP0873331B1 (en) | 2002-04-03 |
| CZ171498A3 (cs) | 1998-10-14 |
| AU1038697A (en) | 1997-06-27 |
| PL327181A1 (en) | 1998-11-23 |
| WO1997020833A1 (en) | 1997-06-12 |
| BR9611897A (pt) | 1999-12-28 |
| EP0873331A1 (en) | 1998-10-28 |
| ATE215540T1 (de) | 2002-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |