CA2221784A1 - Osteogenetic promoting pharmaceutical composition - Google Patents

Osteogenetic promoting pharmaceutical composition Download PDF

Info

Publication number
CA2221784A1
CA2221784A1 CA002221784A CA2221784A CA2221784A1 CA 2221784 A1 CA2221784 A1 CA 2221784A1 CA 002221784 A CA002221784 A CA 002221784A CA 2221784 A CA2221784 A CA 2221784A CA 2221784 A1 CA2221784 A1 CA 2221784A1
Authority
CA
Canada
Prior art keywords
pharmaceutical composition
composition according
acid
groups
biodegradable polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002221784A
Other languages
English (en)
French (fr)
Inventor
Shigehisa Taketomi
Tetsuo Hoshino
Hiroya Muranishi
Susumu Iwasa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2221784A1 publication Critical patent/CA2221784A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/67—Phosphorus compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Polyethers (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002221784A 1995-06-05 1996-06-04 Osteogenetic promoting pharmaceutical composition Abandoned CA2221784A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP13803695 1995-06-05
JP7/138036 1995-06-05
JP8/011686 1996-01-26
JP1168696 1996-01-26

Publications (1)

Publication Number Publication Date
CA2221784A1 true CA2221784A1 (en) 1996-12-12

Family

ID=26347166

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002221784A Abandoned CA2221784A1 (en) 1995-06-05 1996-06-04 Osteogenetic promoting pharmaceutical composition

Country Status (11)

Country Link
EP (1) EP0831808A1 (zh)
KR (1) KR19990022514A (zh)
AR (1) AR003001A1 (zh)
AU (1) AU717260B2 (zh)
CA (1) CA2221784A1 (zh)
HU (1) HUP9802573A3 (zh)
NO (1) NO975636L (zh)
NZ (1) NZ308658A (zh)
RU (1) RU2188011C2 (zh)
TW (1) TW420608B (zh)
WO (1) WO1996039134A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2264131A1 (en) * 1996-08-26 1998-03-05 Takeda Chemical Industries, Ltd. Pharmaceutical composition containing osteogenesis-promoting substance
WO1999065474A2 (en) * 1998-06-15 1999-12-23 Takeda Chemical Industries, Ltd. Compositions for treating cartilage disease comprising certain sulfur-containing heterocyclic compounds
EP1103552A4 (en) 1998-08-07 2003-01-15 Takeda Chemical Industries Ltd BENZOTHIEPINE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE
EP1105140A2 (en) * 1998-08-12 2001-06-13 Takeda Chemical Industries, Ltd. Benzothiepine compounds as enhancer of cell differentiation induction factor
WO2001089521A1 (fr) * 2000-05-23 2001-11-29 Takeda Chemical Industries, Ltd. Compositions medicinales contenant des derives du tiophene
US6926903B2 (en) * 2001-12-04 2005-08-09 Inion Ltd. Resorbable polymer composition, implant and method of making implant
WO2004077948A1 (ja) * 2002-12-19 2004-09-16 Nippon Soda Co., Ltd. Oil/Water液中乾燥法による農薬マイクロカプセル製剤及びその製造方法
JP5960593B2 (ja) 2009-04-27 2016-08-02 プレミア デンタル プロダクツ カンパニー マイクロカプセル化組成物及び組織石灰化の方法
US9814657B2 (en) 2009-04-27 2017-11-14 Premier Dental Products Company Buffered microencapsulated compositions and methods
TWI458503B (zh) * 2013-04-22 2014-11-01 Medical & Pharm Ind Tech & Dev 維生素ｋ微球、其製造方法、用途、及藥劑

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE203020T1 (de) * 1990-05-30 2001-07-15 Takeda Chemical Industries Ltd Schwefel enthaltende heterocyclische verbindungen
US5716944A (en) * 1994-07-04 1998-02-10 Takeda Chemical Industries, Ltd. Phosphonic acid compounds, their production and use
TW403757B (en) * 1994-12-28 2000-09-01 Takeda Chemical Industries Ltd Optically active benzothiepin derivative, its preparation and use

Also Published As

Publication number Publication date
HUP9802573A3 (en) 2000-04-28
AU5845796A (en) 1996-12-24
AR003001A1 (es) 1998-05-27
NZ308658A (en) 1999-10-28
KR19990022514A (ko) 1999-03-25
HUP9802573A2 (hu) 1999-09-28
WO1996039134A1 (en) 1996-12-12
EP0831808A1 (en) 1998-04-01
RU2188011C2 (ru) 2002-08-27
TW420608B (en) 2001-02-01
AU717260B2 (en) 2000-03-23
NO975636L (no) 1998-01-28
NO975636D0 (no) 1997-12-04

Similar Documents

Publication Publication Date Title
JP2992677B2 (ja) 骨形成促進医薬組成物
US6022564A (en) Method for producing a microparticle
US6344209B1 (en) Apatite-coated solid composition
US5910492A (en) Osteogenic promoting pharmaceutical composition
AU717260B2 (en) Osteogenetic promoting pharmaceutical composition
EP0949927A2 (en) Pharmaceutical composition containing osteogenesis-promoting substance and a polyethylene glycol
WO2001010463A1 (fr) Pates a liberation prolongee d'un promoteur de l'osteogenese
JPH115751A (ja) アパタイト被覆固形組成物およびその製造法
CA2345791A1 (en) Bone repair materials and artificial bone compositions
US20030185878A1 (en) Process for producing phospholipid-containing drug
CA2334815A1 (en) Composition for treating cartilage disease
JP2000169375A (ja) 骨修復材・人工骨組成物
JPH10167968A (ja) マイクロパーティクルの製造法
JP2002356419A (ja) 微粒薬物の製造法
JP2001302496A (ja) リポソーム製剤
WO2002078673A1 (fr) Procede de production d'un medicament sous forme de granules fins
JPH10338646A (ja) 骨形成促進医薬組成物
JP2000072678A (ja) 軟骨疾患予防治療剤
CA2340165A1 (en) Enhancer of cell differentiation induction factor
JPH09291040A (ja) 後発白内障治療予防剤
WO2001089521A1 (fr) Compositions medicinales contenant des derives du tiophene
JP2002080400A (ja) リン脂質含有薬物の製造法
JP2002047184A (ja) チオフェン誘導体含有医薬組成物
JPH09235239A (ja) 抗後発白内障剤

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued