CA2221784A1 - Composition pharmaceutique favorisant l'osteogenese - Google Patents

Composition pharmaceutique favorisant l'osteogenese Download PDF

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Publication number
CA2221784A1
CA2221784A1 CA002221784A CA2221784A CA2221784A1 CA 2221784 A1 CA2221784 A1 CA 2221784A1 CA 002221784 A CA002221784 A CA 002221784A CA 2221784 A CA2221784 A CA 2221784A CA 2221784 A1 CA2221784 A1 CA 2221784A1
Authority
CA
Canada
Prior art keywords
pharmaceutical composition
composition according
acid
groups
biodegradable polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002221784A
Other languages
English (en)
Inventor
Shigehisa Taketomi
Tetsuo Hoshino
Hiroya Muranishi
Susumu Iwasa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2221784A1 publication Critical patent/CA2221784A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/67—Phosphorus compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Polyethers (AREA)

Abstract

La composition pharmaceutique décrite contient une substance non peptidique favorisant de l'ostéogénèse et un polymère biodégradable. Cette composition peut être utilisée sans danger comme agent prophylactique/thérapeutique de diverses maladies des os (par exemple fractures).
CA002221784A 1995-06-05 1996-06-04 Composition pharmaceutique favorisant l'osteogenese Abandoned CA2221784A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP13803695 1995-06-05
JP7/138036 1995-06-05
JP8/011686 1996-01-26
JP1168696 1996-01-26

Publications (1)

Publication Number Publication Date
CA2221784A1 true CA2221784A1 (fr) 1996-12-12

Family

ID=26347166

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002221784A Abandoned CA2221784A1 (fr) 1995-06-05 1996-06-04 Composition pharmaceutique favorisant l'osteogenese

Country Status (11)

Country Link
EP (1) EP0831808A1 (fr)
KR (1) KR19990022514A (fr)
AR (1) AR003001A1 (fr)
AU (1) AU717260B2 (fr)
CA (1) CA2221784A1 (fr)
HU (1) HUP9802573A3 (fr)
NO (1) NO975636L (fr)
NZ (1) NZ308658A (fr)
RU (1) RU2188011C2 (fr)
TW (1) TW420608B (fr)
WO (1) WO1996039134A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3868997A (en) * 1996-08-26 1998-03-19 Takeda Chemical Industries Ltd. Pharmaceutical composition containing osteogenesis-promoting substance and a polyethylene glycol
EP1087774A2 (fr) * 1998-06-15 2001-04-04 Takeda Chemical Industries, Ltd. Composition traitant une maladie du cartilage
EP1103552A4 (fr) 1998-08-07 2003-01-15 Takeda Chemical Industries Ltd Derives de benzothiepine, leur procede de preparation et leurs utilisations
WO2000009100A2 (fr) * 1998-08-12 2000-02-24 Takeda Chemical Industries, Ltd. Renforçateur du facteur d'induction de la differenciation cellulaire
WO2001089521A1 (fr) * 2000-05-23 2001-11-29 Takeda Chemical Industries, Ltd. Compositions medicinales contenant des derives du tiophene
US6926903B2 (en) 2001-12-04 2005-08-09 Inion Ltd. Resorbable polymer composition, implant and method of making implant
AU2003289444A1 (en) * 2002-12-19 2004-09-28 Yasuo Hatate Agricultural-chemical microcapsule preparation made by oil/water liquid drying and process for producing the same
EP2424488B1 (fr) 2009-04-27 2023-06-07 Premier Dental Products Company Compositions microencapsulées et procédés de minéralisation tissulaire
US9814657B2 (en) 2009-04-27 2017-11-14 Premier Dental Products Company Buffered microencapsulated compositions and methods
TWI458503B (zh) * 2013-04-22 2014-11-01 Medical & Pharm Ind Tech & Dev 維生素ｋ微球、其製造方法、用途、及藥劑

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0460488T3 (da) * 1990-05-30 2001-09-17 Takeda Chemical Industries Ltd Svovlholdige heterocykliske forbindelser
ATE199721T1 (de) * 1994-07-04 2001-03-15 Takeda Chemical Industries Ltd Phosphonsäure verbindungen imre herstellung und verwendung
TW403757B (en) * 1994-12-28 2000-09-01 Takeda Chemical Industries Ltd Optically active benzothiepin derivative, its preparation and use

Also Published As

Publication number Publication date
NO975636D0 (no) 1997-12-04
AU5845796A (en) 1996-12-24
NO975636L (no) 1998-01-28
HUP9802573A2 (hu) 1999-09-28
AU717260B2 (en) 2000-03-23
TW420608B (en) 2001-02-01
AR003001A1 (es) 1998-05-27
NZ308658A (en) 1999-10-28
EP0831808A1 (fr) 1998-04-01
HUP9802573A3 (en) 2000-04-28
KR19990022514A (ko) 1999-03-25
WO1996039134A1 (fr) 1996-12-12
RU2188011C2 (ru) 2002-08-27

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued