CA2221306A1 - Reagents for labeling sh groups, process for the preparation of them, and method for labeling with them - Google Patents

Reagents for labeling sh groups, process for the preparation of them, and method for labeling with them Download PDF

Info

Publication number
CA2221306A1
CA2221306A1 CA002221306A CA2221306A CA2221306A1 CA 2221306 A1 CA2221306 A1 CA 2221306A1 CA 002221306 A CA002221306 A CA 002221306A CA 2221306 A CA2221306 A CA 2221306A CA 2221306 A1 CA2221306 A1 CA 2221306A1
Authority
CA
Canada
Prior art keywords
group
following formula
represented
carbon atoms
defined above
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002221306A
Other languages
English (en)
French (fr)
Inventor
Kazuhiro Imai
Tadashi Narita
Hiromichi Eto
Takeshi Kotsugai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SSP Co Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP08596696A external-priority patent/JP3220000B2/ja
Priority claimed from JP08596596A external-priority patent/JP3174729B2/ja
Application filed by Individual filed Critical Individual
Publication of CA2221306A1 publication Critical patent/CA2221306A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/06—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
    • C09K11/07—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials having chemically interreactive components, e.g. reactive chemiluminescent compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
CA002221306A 1996-03-15 1997-03-14 Reagents for labeling sh groups, process for the preparation of them, and method for labeling with them Abandoned CA2221306A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP08596696A JP3220000B2 (ja) 1996-03-15 1996-03-15 Ｓｈ基標識用試薬、その製法及びそれを用いた標識法
JP85966/1996 1996-03-15
JP08596596A JP3174729B2 (ja) 1996-03-15 1996-03-15 アクリジン誘導体、その製法およびこれを用いた標識法
JP85965/1996 1996-03-15

Publications (1)

Publication Number Publication Date
CA2221306A1 true CA2221306A1 (en) 1997-09-18

Family

ID=26426974

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002221306A Abandoned CA2221306A1 (en) 1996-03-15 1997-03-14 Reagents for labeling sh groups, process for the preparation of them, and method for labeling with them

Country Status (5)

Country Link
US (1) US6171520B1 (ko)
EP (1) EP0844246A4 (ko)
KR (1) KR100259761B1 (ko)
CA (1) CA2221306A1 (ko)
WO (1) WO1997033884A1 (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998054578A1 (en) * 1997-05-29 1998-12-03 Bio-Rad Laboratories, Inc. Chemiluminescent hemoglobin assay
GB9923146D0 (en) * 1999-09-30 1999-12-01 Imperial College Detector array
CA2448824A1 (en) 2001-06-01 2002-12-12 F. Hoffmann-La Roche Ag Novel compounds for chemiluminescense procedures
ATE423318T1 (de) 2002-10-16 2009-03-15 Univ Duke Biosensor zum nachweis von glukose
US7897787B2 (en) * 2005-09-13 2011-03-01 The University Of Tokyo Maleimide derivative
US8293908B2 (en) * 2007-11-20 2012-10-23 Siemens Healthcare Diagnostics Inc. Facile N-alkylation of acridine compounds in ionic liquids
US8241915B2 (en) * 2009-01-14 2012-08-14 Abbott Laboratories Methods and kits for detecting hemoglobin in test samples
SG174220A1 (en) * 2009-03-05 2011-10-28 Mithridion Inc Compounds and compositions for cognition-enhancement, methods of making, and methods of treating
WO2012033956A1 (en) 2010-09-08 2012-03-15 Mithridion, Inc. Cognition enhancing compounds and compositions, methods of making, and methods of treating
KR20170074178A (ko) * 2015-12-21 2017-06-29 제이엔씨 주식회사 중합성 액정 화합물, 조성물, 그 액정 중합막류 및 이들의 용도

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2112779B (en) * 1981-12-11 1986-10-15 Welsh Nat School Med Aryl acridinium esters as luminescent labelling materials
JPS6261969A (ja) * 1985-09-06 1987-03-18 アモコ・コーポレーション アクリジニウムエステルの合成法
DE3628573C2 (de) * 1986-08-22 1994-10-13 Hoechst Ag Chemilumineszierende Acridinderivate, Verfahren zu deren Herstellung und ihre Verwendung in Lumineszenzimmunoassays
US4745181A (en) 1986-10-06 1988-05-17 Ciba Corning Diagnostics Corp. Polysubstituted aryl acridinium esters
GB2233450B (en) 1989-06-24 1993-06-30 Univ Wales Medicine Detecting or quantifing multiple analytes with luminescent reagents
JP3057887B2 (ja) * 1992-03-03 2000-07-04 和光純薬工業株式会社 新規なマレイミド誘導体、及びこれを用いたチオール基を有する化合物の蛍光標識化方法
JPH05255263A (ja) * 1992-03-10 1993-10-05 Kyowa Medex Co Ltd アクリジウム化合物を用いた物質の測定法
JPH06158039A (ja) * 1992-11-20 1994-06-07 Sanyo Chem Ind Ltd 化学発光性標識剤
US5688642A (en) * 1994-12-01 1997-11-18 The United States Of America As Represented By The Secretary Of The Navy Selective attachment of nucleic acid molecules to patterned self-assembled surfaces

Also Published As

Publication number Publication date
KR100259761B1 (ko) 2000-07-01
KR19990014715A (ko) 1999-02-25
EP0844246A4 (en) 1999-06-02
WO1997033884A1 (fr) 1997-09-18
US6171520B1 (en) 2001-01-09
EP0844246A1 (en) 1998-05-27

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Legal Events

Date Code Title Description
FZDE Discontinued