CA2208939C - Bioabsorbable medical devices from oxidized polysaccharides - Google Patents
Bioabsorbable medical devices from oxidized polysaccharides Download PDFInfo
- Publication number
- CA2208939C CA2208939C CA002208939A CA2208939A CA2208939C CA 2208939 C CA2208939 C CA 2208939C CA 002208939 A CA002208939 A CA 002208939A CA 2208939 A CA2208939 A CA 2208939A CA 2208939 C CA2208939 C CA 2208939C
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- CA
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- Prior art keywords
- cellulose
- oxidized
- bioabsorbable
- water
- process according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- ZFGMDIBRIDKWMY-PASTXAENSA-N heparin Chemical compound CC(O)=N[C@@H]1[C@@H](O)[C@H](O)[C@@H](COS(O)(=O)=O)O[C@@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O[C@H]2[C@@H]([C@@H](OS(O)(=O)=O)[C@@H](O[C@@H]3[C@@H](OC(O)[C@H](OS(O)(=O)=O)[C@H]3O)C(O)=O)O[C@@H]2O)CS(O)(=O)=O)[C@H](O)[C@H]1O ZFGMDIBRIDKWMY-PASTXAENSA-N 0.000 description 1
- 229960001008 heparin sodium Drugs 0.000 description 1
- 229940014041 hyaluronate Drugs 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 208000000509 infertility Diseases 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 231100000535 infertility Toxicity 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 208000003243 intestinal obstruction Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 239000000252 konjac Substances 0.000 description 1
- 235000010485 konjac Nutrition 0.000 description 1
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical compound CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 229940050176 methyl chloride Drugs 0.000 description 1
- 238000007431 microscopic evaluation Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 210000003101 oviduct Anatomy 0.000 description 1
- 239000001254 oxidized starch Substances 0.000 description 1
- 235000013808 oxidized starch Nutrition 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- QUBQYFYWUJJAAK-UHFFFAOYSA-N oxymethurea Chemical compound OCNC(=O)NCO QUBQYFYWUJJAAK-UHFFFAOYSA-N 0.000 description 1
- 229950005308 oxymethurea Drugs 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 238000001050 pharmacotherapy Methods 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 239000003058 plasma substitute Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000036573 scar formation Effects 0.000 description 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 1
- 125000003198 secondary alcohol group Chemical group 0.000 description 1
- 238000007613 slurry method Methods 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229940010747 sodium hyaluronate Drugs 0.000 description 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 210000001179 synovial fluid Anatomy 0.000 description 1
- 238000012385 systemic delivery Methods 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
- 125000001874 trioxidanyl group Chemical group [*]OOO[H] 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 239000002759 woven fabric Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/042—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2075896P | 1996-06-28 | 1996-06-28 | |
| US60/020,758 | 1996-06-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2208939A1 CA2208939A1 (en) | 1997-12-28 |
| CA2208939C true CA2208939C (en) | 2007-09-18 |
Family
ID=21800405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002208939A Expired - Lifetime CA2208939C (en) | 1996-06-28 | 1997-06-26 | Bioabsorbable medical devices from oxidized polysaccharides |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0815879B1 (en, 2012) |
| JP (1) | JPH1066723A (en, 2012) |
| CN (1) | CN1181980A (en, 2012) |
| AU (1) | AU725479B2 (en, 2012) |
| BR (1) | BR9703773A (en, 2012) |
| CA (1) | CA2208939C (en, 2012) |
| DE (1) | DE69738462T2 (en, 2012) |
| ES (1) | ES2299182T3 (en, 2012) |
| IN (1) | IN192791B (en, 2012) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2320502B (en) * | 1996-12-20 | 2000-09-20 | Johnson & Johnson Medical | Bioresorbable alginate derivatives |
| US6440940B1 (en) | 1997-12-18 | 2002-08-27 | Peter J. Doyle | Bioresorbable alginate derivatives |
| GB9810127D0 (en) | 1998-05-13 | 1998-07-08 | Ml Lab Plc | Prevention of surgical adhesions |
| ES2165735T3 (es) * | 1998-05-13 | 2002-03-16 | Ml Lab Plc | Composicion que contiene dextrina para prevenir las adhesiones quirurgicas. |
| ATE491435T1 (de) * | 2000-04-28 | 2011-01-15 | Biolife Llc | Hämostatische wirksubstanz, methode und träger zur verabreichung einer blutgerinnenden wirksubstanz |
| EP1299083B1 (en) * | 2000-06-09 | 2005-04-27 | Genzyme Corporation | Implantable low molecular weight cellulosic compositions |
| US7262181B2 (en) * | 2001-04-30 | 2007-08-28 | Beijing Textile Research Institute | Water soluble cellulose etherified derivatives styptic materials |
| JP4846147B2 (ja) * | 2001-12-17 | 2011-12-28 | 凸版印刷株式会社 | 酸化多糖類材料を被覆又は含浸させた材料の製造方法 |
| US7279177B2 (en) * | 2002-06-28 | 2007-10-09 | Ethicon, Inc. | Hemostatic wound dressings and methods of making same |
| US7252837B2 (en) | 2002-06-28 | 2007-08-07 | Ethicon, Inc. | Hemostatic wound dressing and method of making same |
| US7700500B2 (en) * | 2002-12-23 | 2010-04-20 | Kimberly-Clark Worldwide, Inc. | Durable hydrophilic treatment for a biodegradable polymeric substrate |
| CN1330389C (zh) * | 2003-03-05 | 2007-08-08 | 朱晓明 | 止血凝胶 |
| EP1601388B1 (en) * | 2003-03-10 | 2011-04-27 | Johnson & Johnson Medical Ltd. | Hydrocolloid materials for use in wound healing |
| US7019191B2 (en) | 2003-03-25 | 2006-03-28 | Ethicon, Inc. | Hemostatic wound dressings and methods of making same |
| DE10318802A1 (de) * | 2003-04-17 | 2004-11-04 | Aesculap Ag & Co. Kg | Selbsthaftendes resorbierbares Hämostyptikum |
| US20040241212A1 (en) * | 2003-05-30 | 2004-12-02 | Pendharkar Sanyog Manohar | Biodegradable hemostatic wound dressings |
| US20040265371A1 (en) | 2003-06-25 | 2004-12-30 | Looney Dwayne Lee | Hemostatic devices and methods of making same |
| EP1742692A4 (en) * | 2004-03-17 | 2012-06-27 | Genzyme Corp | ANTI-ADHERENCE SPRAY |
| US7618594B2 (en) | 2004-08-18 | 2009-11-17 | Geno Llc | Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) |
| WO2006023616A2 (en) | 2004-08-18 | 2006-03-02 | Geno Llc | Conversion of nitrogen dioxide (no2) to nitric oxide (no) |
| ES2562727T3 (es) | 2004-10-20 | 2016-03-07 | Ethicon, Inc. | Tejido multicapa absorbible reforzado para su uso en dispositivos médicos y método de fabricación |
| US9358318B2 (en) | 2004-10-20 | 2016-06-07 | Ethicon, Inc. | Method of making a reinforced absorbable multilayered hemostatic wound dressing |
| WO2006044879A2 (en) | 2004-10-20 | 2006-04-27 | Ethicon, Inc. | Absorbable hemostat |
| FR2898502B1 (fr) * | 2006-03-16 | 2012-06-15 | Sofradim Production | Tissu prothetique tridimensionnel a face dense resorbable |
| US8252333B2 (en) | 2006-01-26 | 2012-08-28 | Jorge Cueto-Garcia | Biodegradable, non-toxic biological adhesive for use in abdominal surgery |
| DE102006020498A1 (de) * | 2006-04-20 | 2007-10-25 | Aesculap Ag & Co. Kg | Schichtförmige Wundauflage |
| US8313762B2 (en) | 2006-07-05 | 2012-11-20 | Medtronic Xomed, Inc. | Flexible bioresorbable hemostatic packing and stent |
| CN101313915B (zh) * | 2007-05-30 | 2011-04-20 | 北京泰克美科技有限公司 | 透明质酸及其盐、交联透明质酸及其盐在制备治疗或预防海泡伤药物中的应用 |
| CN101121041A (zh) * | 2007-08-09 | 2008-02-13 | 美国淀粉医疗公司 | 变性淀粉可吸收性止血材料及其制备方法 |
| AU2009209181B2 (en) | 2008-01-28 | 2014-01-16 | VERO Biotech LLC. | Conversion of nitrogen dioxide (NO2) to nitric oxide (NO) |
| US9376648B2 (en) | 2008-04-07 | 2016-06-28 | The Procter & Gamble Company | Foam manipulation compositions containing fine particles |
| CN102883715B (zh) | 2008-04-24 | 2014-11-12 | 麦德托尼克公司 | 包含壳聚糖的保护性组合物 |
| AU2009240510B2 (en) * | 2008-04-24 | 2014-08-21 | Medtronic, Inc. | Rehydratable polysaccharide particles and sponge |
| EP2291524A2 (en) | 2008-04-24 | 2011-03-09 | Medtronic, Inc | Rehydratable thiolated polysaccharide particles and sponge |
| WO2009132227A1 (en) | 2008-04-24 | 2009-10-29 | Medtronic, Inc. | Protective gel based on chitosan and oxidized polysaccharide |
| US8607785B2 (en) | 2008-08-21 | 2013-12-17 | Geno Llc | Systems and devices for generating nitric oxide |
| US8173072B2 (en) | 2008-09-22 | 2012-05-08 | Geno Llc | Conversation of nitrogen dioxide (NO2) to nitric oxide (NO) |
| JP5024262B2 (ja) * | 2008-10-16 | 2012-09-12 | 凸版印刷株式会社 | 酸化多糖類材料を被覆又は含浸させた材料および生体適合材料 |
| AU2010263098B2 (en) | 2009-06-22 | 2016-01-07 | VERO Biotech LLC. | Nitric oxide therapies |
| US8349354B2 (en) * | 2009-09-22 | 2013-01-08 | Ethicon, Inc. | Composite layered hemostasis device |
| DE102009053305A1 (de) | 2009-11-12 | 2011-08-18 | medichema GmbH, 09112 | Verfahren zur Herstellung einer schichtförmigen Wundauflage |
| KR101070358B1 (ko) | 2009-12-24 | 2011-10-05 | 한국생산기술연구원 | 의료용 부직포 및 그의 제조방법 |
| US8409526B2 (en) | 2010-12-09 | 2013-04-02 | General Electric Company | Cellulose substrates, compositions and methods for storage and analysis of biological materials |
| US9987115B2 (en) * | 2011-03-30 | 2018-06-05 | Boston Scientific Scimed, Inc. | Film encapsulated pelvic implant system and method |
| CN102350006A (zh) * | 2011-10-25 | 2012-02-15 | 中国纺织科学研究院 | 医用湿性复合敷料及其制造方法 |
| CN102912622B (zh) * | 2012-10-30 | 2014-07-09 | 威高集团有限公司 | 一种具有表层纳米结构的氧化再生纤维素类止血材料的制备方法 |
| MX2015007771A (es) * | 2012-12-20 | 2015-09-04 | Convatec Technologies Inc | Procesamiento de fibras celulosicas quimicamente modificadas. |
| CN103480033B (zh) * | 2013-10-08 | 2015-10-28 | 江苏昌吉永生物科技有限公司 | 一种医用生物多糖止血愈合海绵及其制备方法 |
| CN103603182B (zh) * | 2013-11-05 | 2016-01-13 | 王学洲 | 可溶性止血纱布及其制备方法 |
| AU2015294612B2 (en) | 2014-07-24 | 2019-07-11 | Arthrocare Corporation | Resilient polysaccharide foams and uses thereof |
| CN104689365A (zh) * | 2015-03-11 | 2015-06-10 | 中南大学 | 一种促创面愈合的复合生物敷料及其制备方法 |
| CN111840633B (zh) * | 2019-04-29 | 2022-08-23 | 上海硅健生物材料有限公司 | 一种皮肤修复膜及其制备方法 |
| CN112107721A (zh) * | 2020-10-22 | 2020-12-22 | 伊索曼(中山)医疗器械有限公司 | 具有生物效应的合成敷料及其制备方法 |
| WO2022177891A1 (en) * | 2021-02-16 | 2022-08-25 | Cornell University | Polysaccharide-glycerol penetration-resistant compositions and surgical barriers made therefrom |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB779820A (en) * | 1954-04-05 | 1957-07-24 | Harry Pauling | Process for the production of cellulose or cellulose containing material having acid properties |
| US4543410A (en) * | 1982-06-21 | 1985-09-24 | Morca, Inc. | Absorbent cellulosic base structures |
| EP0303496A1 (en) * | 1987-08-12 | 1989-02-15 | Ethicon, Inc. | Resorbable surgical meshwork, prostheses of this meshwork and surgical uses thereof |
| US5180398A (en) * | 1990-12-20 | 1993-01-19 | Johnson & Johnson Medical, Inc. | Cellulose oxidation by a perfluorinated hydrocarbon solution of nitrogen dioxide |
-
1997
- 1997-06-25 IN IN1209CA1997 patent/IN192791B/en unknown
- 1997-06-26 AU AU27540/97A patent/AU725479B2/en not_active Expired
- 1997-06-26 CA CA002208939A patent/CA2208939C/en not_active Expired - Lifetime
- 1997-06-27 EP EP97304606A patent/EP0815879B1/en not_active Expired - Lifetime
- 1997-06-27 ES ES97304606T patent/ES2299182T3/es not_active Expired - Lifetime
- 1997-06-27 JP JP9208254A patent/JPH1066723A/ja active Pending
- 1997-06-27 DE DE69738462T patent/DE69738462T2/de not_active Expired - Lifetime
- 1997-06-28 CN CN97117113.0A patent/CN1181980A/zh active Pending
- 1997-06-30 BR BR9703773A patent/BR9703773A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0815879A3 (en) | 1999-12-22 |
| MX9704971A (es) | 1998-05-31 |
| DE69738462D1 (de) | 2008-03-06 |
| EP0815879A2 (en) | 1998-01-07 |
| CA2208939A1 (en) | 1997-12-28 |
| CN1181980A (zh) | 1998-05-20 |
| IN192791B (en, 2012) | 2004-05-22 |
| AU725479B2 (en) | 2000-10-12 |
| EP0815879B1 (en) | 2008-01-16 |
| AU2754097A (en) | 1998-01-22 |
| DE69738462T2 (de) | 2009-01-15 |
| BR9703773A (pt) | 1998-11-10 |
| JPH1066723A (ja) | 1998-03-10 |
| ES2299182T3 (es) | 2008-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20170627 |