CA2198518C - Strains of bacteria and pharmaceutical composition containing such strains and use of same for preventing and treating diseases associated with or caused by alterated metabolism of bile acid - Google Patents

Strains of bacteria and pharmaceutical composition containing such strains and use of same for preventing and treating diseases associated with or caused by alterated metabolism of bile acid

Info

Publication number
CA2198518C
CA2198518C CA2198518A CA2198518A CA2198518C CA 2198518 C CA2198518 C CA 2198518C CA 2198518 A CA2198518 A CA 2198518A CA 2198518 A CA2198518 A CA 2198518A CA 2198518 C CA2198518 C CA 2198518C
Authority
CA
Canada
Prior art keywords
strain
cultures
microorganismes
cncm
deposited
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2198518A
Other languages
English (en)
French (fr)
Other versions
CA2198518A1 (en
Inventor
Renata Maria Anna Cavaliere Vesely
Claudio De Simone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11373572&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2198518(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CA2198518A1 publication Critical patent/CA2198518A1/en
Application granted granted Critical
Publication of CA2198518C publication Critical patent/CA2198518C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016Disaccharides, e.g. lactose, lactulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225Lactobacillus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46Streptococcus ; Enterococcus; Lactococcus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2198518A 1996-03-11 1997-02-26 Strains of bacteria and pharmaceutical composition containing such strains and use of same for preventing and treating diseases associated with or caused by alterated metabolism of bile acid Expired - Fee Related CA2198518C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI96A000468 1996-03-11
IT96MI000468A IT1283225B1 (it) 1996-03-11 1996-03-11 Ceppi di batteri, composizione farmaceutica contenente uno o piu' di tali ceppi e uso dei medesimi per la prevenzione e la terapia delle

Publications (2)

Publication Number Publication Date
CA2198518A1 CA2198518A1 (en) 1997-09-11
CA2198518C true CA2198518C (en) 2010-04-13

Family

ID=11373572

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2198518A Expired - Fee Related CA2198518C (en) 1996-03-11 1997-02-26 Strains of bacteria and pharmaceutical composition containing such strains and use of same for preventing and treating diseases associated with or caused by alterated metabolism of bile acid

Country Status (13)

Country Link
US (6) US6225104B1 (enExample)
EP (1) EP0795604B1 (enExample)
JP (1) JP4057091B2 (enExample)
KR (1) KR100472061B1 (enExample)
CN (1) CN1110547C (enExample)
AT (1) ATE246509T1 (enExample)
CA (1) CA2198518C (enExample)
DE (1) DE69723898T2 (enExample)
DK (1) DK0795604T3 (enExample)
ES (1) ES2200145T3 (enExample)
IT (1) IT1283225B1 (enExample)
MX (1) MX9701816A (enExample)
PT (1) PT795604E (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283225B1 (it) * 1996-03-11 1998-04-16 Renata Maria Anna Ve Cavaliere Ceppi di batteri, composizione farmaceutica contenente uno o piu' di tali ceppi e uso dei medesimi per la prevenzione e la terapia delle
IT1309427B1 (it) * 1999-05-28 2002-01-23 Mendes S U R L Composizione dietetica o farmaceutica utile per la prevenzione o iltrattamento dell'iperossaluria e suo uso
IT1306716B1 (it) * 1999-06-21 2001-10-02 Mendes S U R L Associazione di batteri lattici e suo uso per la prevenzione e/o iltrattamento terapeutico di infezioni e di stati infiammatori.
ITRM20010763A1 (it) * 2001-12-21 2003-06-21 Simone Claudio De Nuovo ceppo di batterio lattico e composizioni commestibili, farmaci e prodotti veterinari che lo contengono.
US7374606B2 (en) * 2003-06-27 2008-05-20 Canon Kabushiki Kaisha Water-based ink and ink recording method
US7985564B2 (en) * 2003-11-21 2011-07-26 Pfenex, Inc. Expression systems with sec-system secretion
CN1663573B (zh) * 2004-03-04 2010-04-28 青岛东海药业有限公司 一种稳定安全的微生态制剂及其制备方法和用途
WO2005094848A1 (ja) * 2004-03-31 2005-10-13 Calpis Co., Ltd. 肝障害予防又は抑制剤及び肝障害予防又は抑制用機能性食品
EP2468869B1 (en) * 2007-01-31 2015-03-18 Pfenex Inc. Bacterial leader sequences for increased expression
PL2266619T3 (pl) * 2008-03-04 2015-10-30 Dikovskiy Aleksander Vladimirovich Kompozycja farmaceutyczna na bazie środków chroniących wątrobę i środków prebiotycznych, ich wytwarzanie i zastosowanie
KR20220042485A (ko) * 2012-01-16 2022-04-05 엘라자베스 맥켄나 간 질환들 및 장애들의 치료를 위한 조성물들 및 방법들
US12268718B2 (en) 2012-01-16 2025-04-08 Labyrinth Holdings Llc Control of cellular redox levels
EP2898073A4 (en) 2012-09-21 2016-03-23 Elizabeth Mckenna Naturally-occurring CPG-oligonucleotide compositions and therapeutic applications thereof
EP3172973B1 (en) * 2015-11-27 2020-04-08 DAFLORN Ltd. Probiotic formula, process of its preparation and use
BR112018012022A2 (pt) * 2015-12-14 2018-12-04 Metabogen Ab ?composição, e, método para tratamento ou redução do risco de colestase intra-hepática?
CN115569141B (zh) * 2022-10-17 2023-10-20 中国农业科学院兰州兽医研究所 脱氧胆酸在制备抗口腔链球菌产品中的应用
WO2025094993A1 (ja) * 2023-10-31 2025-05-08 国立大学法人大阪大学 Mait細胞リガンドの同定のための細胞、および当該細胞を用いるmait細胞リガンドのスクリーニング方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1221734B (it) * 1983-02-24 1990-07-12 Schiena Michele Giuseppe Di Ursodesossicolico solfato acido sale sodico
US5079240A (en) * 1990-03-15 1992-01-07 The Regents Of The University Of California Synthetic conjugated bile acid and method of use thereof
US5716615A (en) * 1992-02-10 1998-02-10 Renata Maria Anna Cavaliere Vesely Dietary and pharmaceutical compositions containing lyophilized lactic bacteria, their preparation and use
IT1255241B (it) * 1992-07-22 1995-10-20 Simos Contos Derivato di acido biliare e suo uso in terapia
JP2992945B2 (ja) * 1994-03-11 1999-12-20 カルピス株式会社 ラクトバチルス・アシドフィルス乳酸菌
IT1283225B1 (it) * 1996-03-11 1998-04-16 Renata Maria Anna Ve Cavaliere Ceppi di batteri, composizione farmaceutica contenente uno o piu' di tali ceppi e uso dei medesimi per la prevenzione e la terapia delle
DE69600525T2 (de) * 1996-12-23 1998-12-10 Sitia-Yomo S.P.A., Mailand/Milano Lyophilisierte, lebende Bakerien enthaltende Nahrungszusammensetzung
IT1309427B1 (it) * 1999-05-28 2002-01-23 Mendes S U R L Composizione dietetica o farmaceutica utile per la prevenzione o iltrattamento dell'iperossaluria e suo uso
ITRM20010763A1 (it) * 2001-12-21 2003-06-21 Simone Claudio De Nuovo ceppo di batterio lattico e composizioni commestibili, farmaci e prodotti veterinari che lo contengono.
TWI241912B (en) * 2002-10-30 2005-10-21 Food Industry Res & Dev Inst Novel Acid-and bile salt-resistant Lactobacillus isolates having the ability to lower and assimilate cholesterol

Also Published As

Publication number Publication date
ITMI960468A1 (it) 1997-09-11
DK0795604T3 (da) 2003-10-27
EP0795604B1 (en) 2003-08-06
ITMI960468A0 (enExample) 1996-03-11
US20030082791A1 (en) 2003-05-01
US6225104B1 (en) 2001-05-01
JPH1086A (ja) 1998-01-06
CN1165857A (zh) 1997-11-26
PT795604E (pt) 2003-12-31
ATE246509T1 (de) 2003-08-15
US20110217759A1 (en) 2011-09-08
KR100472061B1 (ko) 2005-07-08
DE69723898D1 (de) 2003-09-11
MX9701816A (es) 1998-04-30
US20040259227A1 (en) 2004-12-23
US20010012629A1 (en) 2001-08-09
CN1110547C (zh) 2003-06-04
JP4057091B2 (ja) 2008-03-05
US7959911B2 (en) 2011-06-14
USRE41276E1 (en) 2010-04-27
CA2198518A1 (en) 1997-09-11
IT1283225B1 (it) 1998-04-16
DE69723898T2 (de) 2004-01-29
KR970065708A (ko) 1997-10-13
EP0795604A2 (en) 1997-09-17
ES2200145T3 (es) 2004-03-01
EP0795604A3 (en) 1998-04-15

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