CN1110547C - 细菌菌株和包含它们的药物组合物以及该菌株在预防和治疗疾病上的用途 - Google Patents

细菌菌株和包含它们的药物组合物以及该菌株在预防和治疗疾病上的用途 Download PDF

Info

Publication number
CN1110547C
CN1110547C CN97103444A CN97103444A CN1110547C CN 1110547 C CN1110547 C CN 1110547C CN 97103444 A CN97103444 A CN 97103444A CN 97103444 A CN97103444 A CN 97103444A CN 1110547 C CN1110547 C CN 1110547C
Authority
CN
China
Prior art keywords
bacterial strain
cncm
institut pasteur
microorganisms
deposited
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CN97103444A
Other languages
English (en)
Chinese (zh)
Other versions
CN1165857A (zh
Inventor
Ｒ·Ｍ·Ａ·卡维里尔井伟斯丽
C·德斯墨尼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11373572&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1110547(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CN1165857A publication Critical patent/CN1165857A/zh
Application granted granted Critical
Publication of CN1110547C publication Critical patent/CN1110547C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46—Streptococcus ; Enterococcus; Lactococcus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN97103444A 1996-03-11 1997-03-10 细菌菌株和包含它们的药物组合物以及该菌株在预防和治疗疾病上的用途 Expired - Lifetime CN1110547C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT96MI000468A IT1283225B1 (it) 1996-03-11 1996-03-11 Ceppi di batteri, composizione farmaceutica contenente uno o piu' di tali ceppi e uso dei medesimi per la prevenzione e la terapia delle
ITMI96A000468 1996-03-11

Publications (2)

Publication Number Publication Date
CN1165857A CN1165857A (zh) 1997-11-26
CN1110547C true CN1110547C (zh) 2003-06-04

Family

ID=11373572

Family Applications (1)

Application Number Title Priority Date Filing Date
CN97103444A Expired - Lifetime CN1110547C (zh) 1996-03-11 1997-03-10 细菌菌株和包含它们的药物组合物以及该菌株在预防和治疗疾病上的用途

Country Status (13)

Country Link
US (6) US6225104B1 (enExample)
EP (1) EP0795604B1 (enExample)
JP (1) JP4057091B2 (enExample)
KR (1) KR100472061B1 (enExample)
CN (1) CN1110547C (enExample)
AT (1) ATE246509T1 (enExample)
CA (1) CA2198518C (enExample)
DE (1) DE69723898T2 (enExample)
DK (1) DK0795604T3 (enExample)
ES (1) ES2200145T3 (enExample)
IT (1) IT1283225B1 (enExample)
MX (1) MX9701816A (enExample)
PT (1) PT795604E (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283225B1 (it) * 1996-03-11 1998-04-16 Renata Maria Anna Ve Cavaliere Ceppi di batteri, composizione farmaceutica contenente uno o piu' di tali ceppi e uso dei medesimi per la prevenzione e la terapia delle
IT1309427B1 (it) 1999-05-28 2002-01-23 Mendes S U R L Composizione dietetica o farmaceutica utile per la prevenzione o iltrattamento dell'iperossaluria e suo uso
IT1306716B1 (it) * 1999-06-21 2001-10-02 Mendes S U R L Associazione di batteri lattici e suo uso per la prevenzione e/o iltrattamento terapeutico di infezioni e di stati infiammatori.
ITRM20010763A1 (it) * 2001-12-21 2003-06-21 Simone Claudio De Nuovo ceppo di batterio lattico e composizioni commestibili, farmaci e prodotti veterinari che lo contengono.
US7374606B2 (en) * 2003-06-27 2008-05-20 Canon Kabushiki Kaisha Water-based ink and ink recording method
CN1882605B (zh) * 2003-11-21 2012-07-11 陶氏环球技术公司 使用Sec-系统分泌的改进的表达系统
CN1663573B (zh) * 2004-03-04 2010-04-28 青岛东海药业有限公司 一种稳定安全的微生态制剂及其制备方法和用途
EP1736164A4 (en) * 2004-03-31 2009-06-24 Calpis Co Ltd AGENT TO PREVENT OR REMOVE HEPATOPATHY AND FUNCTIONAL FEED TO PREVENT OR DELETE HEPATOPATHY
CA2677179C (en) * 2007-01-31 2016-02-16 Dow Global Technologies Inc. Bacterial leader sequences for increased expression
SI2266619T1 (sl) * 2008-03-04 2015-11-30 Dikovskiy, Aleksander Vladimirovich Farmacevtski sestavek na osnovi hepatoprotektorja in prebiotika, njegova izdelava in uporaba
US12268718B2 (en) 2012-01-16 2025-04-08 Labyrinth Holdings Llc Control of cellular redox levels
US20140086849A1 (en) 2012-09-21 2014-03-27 Elizabeth McKenna Naturally-Occurring CpG Oligonucleotide Compositions and Therapeutic Applications Thereof
AU2013209887B2 (en) 2012-01-16 2021-02-18 Elizabeth Mckenna Compositions and methods for the treatment of hepatic diseases and disorders
EP3172973B1 (en) * 2015-11-27 2020-04-08 DAFLORN Ltd. Probiotic formula, process of its preparation and use
CA3008195A1 (en) * 2015-12-14 2017-06-22 Metabogen Ab Treatment of intrahepatic cholestasis and related liver diseases
CN115569141B (zh) * 2022-10-17 2023-10-20 中国农业科学院兰州兽医研究所 脱氧胆酸在制备抗口腔链球菌产品中的应用
WO2025094993A1 (ja) * 2023-10-31 2025-05-08 国立大学法人大阪大学 Ｍａｉｔ細胞リガンドの同定のための細胞、および当該細胞を用いるｍａｉｔ細胞リガンドのスクリーニング方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0671468A1 (en) * 1994-03-11 1995-09-13 The Calpis Food Industry Co., Ltd. Lactic acid bacteria of the genus lactobacillus

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1221734B (it) * 1983-02-24 1990-07-12 Schiena Michele Giuseppe Di Ursodesossicolico solfato acido sale sodico
US5079240A (en) * 1990-03-15 1992-01-07 The Regents Of The University Of California Synthetic conjugated bile acid and method of use thereof
US5716615A (en) * 1992-02-10 1998-02-10 Renata Maria Anna Cavaliere Vesely Dietary and pharmaceutical compositions containing lyophilized lactic bacteria, their preparation and use
IT1255241B (it) * 1992-07-22 1995-10-20 Simos Contos Derivato di acido biliare e suo uso in terapia
IT1283225B1 (it) * 1996-03-11 1998-04-16 Renata Maria Anna Ve Cavaliere Ceppi di batteri, composizione farmaceutica contenente uno o piu' di tali ceppi e uso dei medesimi per la prevenzione e la terapia delle
EP0856259B1 (en) * 1996-12-23 1998-08-12 SITIA-YOMO S.p.A. Composition for feed use comprising lyophilized live lactic bacteria
IT1309427B1 (it) * 1999-05-28 2002-01-23 Mendes S U R L Composizione dietetica o farmaceutica utile per la prevenzione o iltrattamento dell'iperossaluria e suo uso
ITRM20010763A1 (it) * 2001-12-21 2003-06-21 Simone Claudio De Nuovo ceppo di batterio lattico e composizioni commestibili, farmaci e prodotti veterinari che lo contengono.
TWI241912B (en) * 2002-10-30 2005-10-21 Food Industry Res & Dev Inst Novel Acid-and bile salt-resistant Lactobacillus isolates having the ability to lower and assimilate cholesterol

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0671468A1 (en) * 1994-03-11 1995-09-13 The Calpis Food Industry Co., Ltd. Lactic acid bacteria of the genus lactobacillus

Also Published As

Publication number Publication date
US20040259227A1 (en) 2004-12-23
PT795604E (pt) 2003-12-31
ES2200145T3 (es) 2004-03-01
EP0795604B1 (en) 2003-08-06
US20110217759A1 (en) 2011-09-08
EP0795604A3 (en) 1998-04-15
DE69723898T2 (de) 2004-01-29
DE69723898D1 (de) 2003-09-11
USRE41276E1 (en) 2010-04-27
JPH1086A (ja) 1998-01-06
KR100472061B1 (ko) 2005-07-08
US7959911B2 (en) 2011-06-14
CA2198518A1 (en) 1997-09-11
DK0795604T3 (da) 2003-10-27
ITMI960468A0 (enExample) 1996-03-11
CA2198518C (en) 2010-04-13
ITMI960468A1 (it) 1997-09-11
EP0795604A2 (en) 1997-09-17
ATE246509T1 (de) 2003-08-15
US6225104B1 (en) 2001-05-01
CN1165857A (zh) 1997-11-26
US20030082791A1 (en) 2003-05-01
IT1283225B1 (it) 1998-04-16
KR970065708A (ko) 1997-10-13
MX9701816A (es) 1998-04-30
US20010012629A1 (en) 2001-08-09
JP4057091B2 (ja) 2008-03-05

Similar Documents

Publication Publication Date Title
US20110217759A1 (en) Strains of bacteria and pharmaceutical composition containing one or more of such strains and use of same for preventing and treating diseases associated with or caused by altered metabolism of bile acids
AU673525B2 (en) Lactic acid bacterium
Hentges Human intestinal microflora in health and disease
EP0199535B1 (en) Lactobacillus acidophilus strains of bacteria and compositions thereof
Dickinson et al. Determination of bile acid conversion potencies of intestinal bacteria by screening in vitro and subsequent establishment in germfree rats
EP1481681A1 (en) Lactic acid bacteria combination and compositions thereof
US20220331378A1 (en) Compositions and methods for treating autism spectrum disorder
JPS60149527A (ja) 生体内脱臭剤
Stotzer et al. Probiotic treatment of small intestinal bacterial overgrowth by Lactobacillus fermentum KLD
MXPA97001816A (en) Bacterials and pharmaceutical composition containing such strains and using the same to prevent and treat diseases associated with metabolism altered biliary deactives or caused by my
CN113755409A (zh) 一种缓解胰岛素抵抗的长双歧杆菌及其应用
Ma et al. A postbiotic exopolysaccharide synergizes with Lactobacillus acidophilus to reduce intestinal inflammation in a mouse model of colitis
US20120121753A1 (en) Compositions and methods for prevention and treatment of obesity and obesity related metabolic syndrome
CN115074277A (zh) 一株可缓解肥胖的普拉梭菌及其应用
CN113637603A (zh) 赋予食物成分抗癌效能的肠道乳杆菌及其应用
WO2021097288A1 (en) Compositions and methods for treating neurodegenerative diseases
CN111172054B (zh) 一种干酪乳杆菌组合制剂及其应用
WO2021142353A1 (en) Compositions and methods for treating hepatitis b (hbv) and hepatitis d (hdv)
Narushima et al. Caecal bile acid compositions in gnotobiotic mice associated with human intestinal bacteria with the ability to transform bile acids in vitro
WO2021142347A1 (en) Compositions and methods for non-alcoholic steatohepatitis (nash)
EP3370751B1 (en) Lentil extract with cholesterol lowering and prebiotic activity
Pistoli et al. Differences in the faecal flora of healthy individuals and patients with irritable bowel syndrome, and in vitro effects of a synbiotic upon gut flora composition
CN119120275A (zh) 一种丁酸产生菌及其应用
WO2008026444A1 (en) Aid for irrigating gastrointestinal tract comprising butyric acid bacteria and/or lactic acid bacteria
Santarpia et al. Stable reversal of primitive intestinal lymphangiectasia

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CI01 Publication of corrected invention patent application

Correction item: Patentee

Correct: R M A says Lille Wei Rita

False: R - M - A - kaavi wells of Lille Wei Rita

Number: 23

Page: 331

Volume: 19

Correction item: Inventor

Correct: R M A says Lille Wei Rita

False: R - M - A - kaavi wells of Lille Wei Rita

Number: 23

Page: 331

Volume: 19

CI03 Correction of invention patent

Correction item: Patentee

Correct: R M A says Lille Wei Rita

False: R - M - A - kaavi wells of Lille Wei Rita

Number: 23

Page: The title page

Volume: 19

Correction item: Inventor

Correct: R M A says Lille Wei Rita

False: R - M - A - kaavi wells of Lille Wei Rita

Number: 23

Page: The title page

Volume: 19

COR Change of bibliographic data

Free format text: CORRECT: PATENTEE INVENTOR; FROM: R M A KAWI LILLE WELL RITA WEI R M A KAWI LILLE WELL RITA WEI TO: RENATA MARIA ANNA CAVALIERE VESELY RENATA MARIA ANNA CAVALIERE VESELY

ERR Gazette correction

Free format text: CORRECT: PATENTEE INVENTOR; FROM: R M A KAWI LILLE WELL RITA WEI R M A KAWI LILLE WELL RITA WEI TO: RENATA MARIA ANNA CAVALIERE VESELY RENATA MARIA ANNA CAVALIERE VESELY

REG Reference to a national code

Ref country code: HK

Ref legal event code: GR

Ref document number: 1027182

Country of ref document: HK

CX01 Expiry of patent term

Granted publication date: 20030604

CX01 Expiry of patent term