DE69723898D1 - Bakterien-Stämme mit verändertem Gallensäuren-Stoffwechsel und deren Verwendung - Google Patents

Bakterien-Stämme mit verändertem Gallensäuren-Stoffwechsel und deren Verwendung

Info

Publication number
DE69723898D1
DE69723898D1 DE69723898T DE69723898T DE69723898D1 DE 69723898 D1 DE69723898 D1 DE 69723898D1 DE 69723898 T DE69723898 T DE 69723898T DE 69723898 T DE69723898 T DE 69723898T DE 69723898 D1 DE69723898 D1 DE 69723898D1
Authority
DE
Germany
Prior art keywords
bile acid
bacterial strains
acid metabolism
strains
altered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69723898T
Other languages
English (en)
Other versions
DE69723898T2 (de
Inventor
Simone Claudio De
Vesely Renata Maria Cavaliere
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VESELY ALESSANDRO
VESELY MARINA EVA
VESELY SARA
Original Assignee
VESELY ALESSANDRO
VESELY MARINA EVA
VESELY SARA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11373572&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69723898(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by VESELY ALESSANDRO, VESELY MARINA EVA, VESELY SARA filed Critical VESELY ALESSANDRO
Publication of DE69723898D1 publication Critical patent/DE69723898D1/de
Application granted granted Critical
Publication of DE69723898T2 publication Critical patent/DE69723898T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016Disaccharides, e.g. lactose, lactulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225Lactobacillus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46Streptococcus ; Enterococcus; Lactococcus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69723898T 1996-03-11 1997-02-05 Bakterien-Stämme mit verändertem Gallensäuren-Stoffwechsel und deren Verwendung Expired - Lifetime DE69723898T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT96MI000468A IT1283225B1 (it) 1996-03-11 1996-03-11 Ceppi di batteri, composizione farmaceutica contenente uno o piu' di tali ceppi e uso dei medesimi per la prevenzione e la terapia delle

Publications (2)

Publication Number Publication Date
DE69723898D1 true DE69723898D1 (de) 2003-09-11
DE69723898T2 DE69723898T2 (de) 2004-01-29

Family

ID=11373572

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69723898T Expired - Lifetime DE69723898T2 (de) 1996-03-11 1997-02-05 Bakterien-Stämme mit verändertem Gallensäuren-Stoffwechsel und deren Verwendung

Country Status (13)

Country Link
US (6) US6225104B1 (de)
EP (1) EP0795604B1 (de)
JP (1) JP4057091B2 (de)
KR (1) KR100472061B1 (de)
CN (1) CN1110547C (de)
AT (1) ATE246509T1 (de)
CA (1) CA2198518C (de)
DE (1) DE69723898T2 (de)
DK (1) DK0795604T3 (de)
ES (1) ES2200145T3 (de)
IT (1) IT1283225B1 (de)
MX (1) MX9701816A (de)
PT (1) PT795604E (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283225B1 (it) * 1996-03-11 1998-04-16 Renata Maria Anna Ve Cavaliere Ceppi di batteri, composizione farmaceutica contenente uno o piu' di tali ceppi e uso dei medesimi per la prevenzione e la terapia delle
IT1309427B1 (it) * 1999-05-28 2002-01-23 Mendes S U R L Composizione dietetica o farmaceutica utile per la prevenzione o iltrattamento dell'iperossaluria e suo uso
IT1306716B1 (it) * 1999-06-21 2001-10-02 Mendes S U R L Associazione di batteri lattici e suo uso per la prevenzione e/o iltrattamento terapeutico di infezioni e di stati infiammatori.
ITRM20010763A1 (it) * 2001-12-21 2003-06-21 Simone Claudio De Nuovo ceppo di batterio lattico e composizioni commestibili, farmaci e prodotti veterinari che lo contengono.
US7374606B2 (en) * 2003-06-27 2008-05-20 Canon Kabushiki Kaisha Water-based ink and ink recording method
EP1687324B1 (de) * 2003-11-21 2012-08-22 Pfenex, Inc. Verbessertes expressionssystem mit sec-system-sekretion
CN1663573B (zh) * 2004-03-04 2010-04-28 青岛东海药业有限公司 一种稳定安全的微生态制剂及其制备方法和用途
TW200536552A (en) * 2004-03-31 2005-11-16 Calpis Co Ltd Hepatopathy preventive or inhibitory agents and functional food for preventing or inhibiting hepatopathy
JP5714230B2 (ja) * 2007-01-31 2015-05-07 フェネックス インコーポレイテッド 発現上昇のための細菌リーダー配列
DK2266619T3 (en) * 2008-03-04 2015-08-24 Dikovskiy Aleksander Vladimirovich PHARMACEUTICAL PREPARATION BASED ON A LIVING PROTECTIVE AGENT AND A PREBIOTIC AGENT, PREPARATION AND USE OF IT
CN104144693A (zh) 2012-01-16 2014-11-12 E·麦肯纳 用于治疗肝脏疾病和障碍的组合物和方法
EP2898073A4 (de) 2012-09-21 2016-03-23 Elizabeth Mckenna Natürlich vorkommende cpg-oligonukleotidzusammensetzungen und therapeutische anwendungen davon
EP3172973B1 (de) * 2015-11-27 2020-04-08 DAFLORN Ltd. Probiotische formel, verfahren zu deren herstellung und verwendung
MX2018007227A (es) * 2015-12-14 2018-08-01 Metabogen Ab Tratamiento de colestasis intrahepatica y enfermedades hepaticas relacionadas.
CN115569141B (zh) * 2022-10-17 2023-10-20 中国农业科学院兰州兽医研究所 脱氧胆酸在制备抗口腔链球菌产品中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1221734B (it) * 1983-02-24 1990-07-12 Schiena Michele Giuseppe Di Ursodesossicolico solfato acido sale sodico
US5079240A (en) * 1990-03-15 1992-01-07 The Regents Of The University Of California Synthetic conjugated bile acid and method of use thereof
US5716615A (en) * 1992-02-10 1998-02-10 Renata Maria Anna Cavaliere Vesely Dietary and pharmaceutical compositions containing lyophilized lactic bacteria, their preparation and use
IT1255241B (it) * 1992-07-22 1995-10-20 Simos Contos Derivato di acido biliare e suo uso in terapia
JP2992945B2 (ja) * 1994-03-11 1999-12-20 カルピス株式会社 ラクトバチルス・アシドフィルス乳酸菌
IT1283225B1 (it) * 1996-03-11 1998-04-16 Renata Maria Anna Ve Cavaliere Ceppi di batteri, composizione farmaceutica contenente uno o piu' di tali ceppi e uso dei medesimi per la prevenzione e la terapia delle
EP0856259B1 (de) * 1996-12-23 1998-08-12 SITIA-YOMO S.p.A. Lyophilisierte, lebende Bakerien enthaltende Nahrungszusammensetzung
IT1309427B1 (it) * 1999-05-28 2002-01-23 Mendes S U R L Composizione dietetica o farmaceutica utile per la prevenzione o iltrattamento dell'iperossaluria e suo uso
ITRM20010763A1 (it) * 2001-12-21 2003-06-21 Simone Claudio De Nuovo ceppo di batterio lattico e composizioni commestibili, farmaci e prodotti veterinari che lo contengono.
TWI241912B (en) * 2002-10-30 2005-10-21 Food Industry Res & Dev Inst Novel Acid-and bile salt-resistant Lactobacillus isolates having the ability to lower and assimilate cholesterol

Also Published As

Publication number Publication date
IT1283225B1 (it) 1998-04-16
ES2200145T3 (es) 2004-03-01
KR100472061B1 (ko) 2005-07-08
US20010012629A1 (en) 2001-08-09
MX9701816A (es) 1998-04-30
PT795604E (pt) 2003-12-31
ATE246509T1 (de) 2003-08-15
EP0795604B1 (de) 2003-08-06
US20040259227A1 (en) 2004-12-23
DK0795604T3 (da) 2003-10-27
US7959911B2 (en) 2011-06-14
US6225104B1 (en) 2001-05-01
DE69723898T2 (de) 2004-01-29
ITMI960468A0 (de) 1996-03-11
CN1165857A (zh) 1997-11-26
EP0795604A2 (de) 1997-09-17
JPH1086A (ja) 1998-01-06
CN1110547C (zh) 2003-06-04
US20030082791A1 (en) 2003-05-01
ITMI960468A1 (it) 1997-09-11
CA2198518C (en) 2010-04-13
EP0795604A3 (de) 1998-04-15
JP4057091B2 (ja) 2008-03-05
USRE41276E1 (en) 2010-04-27
KR970065708A (ko) 1997-10-13
CA2198518A1 (en) 1997-09-11
US20110217759A1 (en) 2011-09-08

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Legal Events

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