CA2193236A1 - Improved chichibabin aminations of pyridine bases - Google Patents

Improved chichibabin aminations of pyridine bases

Info

Publication number
CA2193236A1
CA2193236A1 CA 2193236 CA2193236A CA2193236A1 CA 2193236 A1 CA2193236 A1 CA 2193236A1 CA 2193236 CA2193236 CA 2193236 CA 2193236 A CA2193236 A CA 2193236A CA 2193236 A1 CA2193236 A1 CA 2193236A1
Authority
CA
Canada
Prior art keywords
alkyl
lower alkyl
pyridine
reaction mixture
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2193236
Other languages
English (en)
French (fr)
Inventor
Phillip B. Lawin
Angela R. Sherman
Martin P. Grendze
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vertellus Specialties Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2193236A1 publication Critical patent/CA2193236A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA 2193236 1994-06-24 1995-06-26 Improved chichibabin aminations of pyridine bases Abandoned CA2193236A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US26532194A 1994-06-24 1994-06-24
US08/265,321 1994-06-24
US48044095A 1995-06-07 1995-06-07
US08/480,440 1995-06-07

Publications (1)

Publication Number Publication Date
CA2193236A1 true CA2193236A1 (en) 1996-01-04

Family

ID=26951123

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2193236 Abandoned CA2193236A1 (en) 1994-06-24 1995-06-26 Improved chichibabin aminations of pyridine bases

Country Status (11)

Country Link
EP (1) EP0766675A4 (zh)
JP (1) JPH10502089A (zh)
CN (1) CN1156990A (zh)
AU (1) AU703530B2 (zh)
BR (1) BR9508123A (zh)
CA (1) CA2193236A1 (zh)
HU (1) HU217172B (zh)
IL (1) IL114314A (zh)
MX (1) MX9606724A (zh)
TW (1) TW306915B (zh)
WO (1) WO1996000216A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2952504B1 (en) * 2013-02-01 2017-10-11 Sophia School Corporation Method for producing desmosine, isodesmosine and derivatives thereof
CN104447523B (zh) * 2014-11-27 2017-05-17 安徽星宇化工有限公司 一种由吡啶碱混合物合成氨基吡啶的方法及其分离纯化方法
CN114409593B (zh) * 2022-01-20 2024-02-23 上海泾维化工科技有限公司 一种2-氨基-5-甲基吡啶的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405790A (en) * 1982-04-08 1983-09-20 Reilly Tar & Chemical Corp. Process for preparing 2-alkylamino- and 2-amino-5-alkylpyridines
US4386209A (en) * 1982-04-08 1983-05-31 Reilly Tar & Chemical Corporation Chichibabin reaction

Also Published As

Publication number Publication date
AU703530B2 (en) 1999-03-25
BR9508123A (pt) 1997-08-12
EP0766675A1 (en) 1997-04-09
TW306915B (zh) 1997-06-01
HU217172B (hu) 1999-12-28
HUT76424A (en) 1997-08-28
CN1156990A (zh) 1997-08-13
WO1996000216A1 (en) 1996-01-04
EP0766675A4 (en) 1997-09-24
AU2910095A (en) 1996-01-19
MX9606724A (es) 1997-03-29
IL114314A (en) 2000-12-06
JPH10502089A (ja) 1998-02-24
HU9603557D0 (en) 1997-02-28

Similar Documents

Publication Publication Date Title
Ritter et al. Synthesis and reactions of dinitrated amino and diaminopyridines
WO2007069685A1 (ja) 選択的一級アミン化合物の製造方法
Parrot et al. Synthesis of substituted 3-amino-6-arylpyridazines via Suzuki reaction
US4386209A (en) Chichibabin reaction
US4158093A (en) Process for substituting and dequaternizing pyridylethyl quaternary salts of pyridine and bypyridine bases
CA2193236A1 (en) Improved chichibabin aminations of pyridine bases
JP2006070034A (ja) ２−アミノピリジン誘導体の製造方法
CN111732536A (zh) 氨基吡啶类化合物的合成方法
US5808081A (en) Chichibabin aminations of pyridine bases
EP0331899B1 (en) A method for the sequential oxidation of substituted-8-hydroxy-quinolines to produce substituted-pyridine-2,3-dicarboxylic acids
US5614636A (en) Process for the preparation of 2,4-pyridine dicarboxylic acid
JPS62209063A (ja) ピリジン−２，３−ジカルボン酸の製造方法
RU2165414C2 (ru) Усовершенствованный способ аминирования пиридиновых оснований по чичибабину
EP0973704B1 (en) Process for the manufacture of arylsulfonyl chloride
Peereboom et al. Ring transformations in reactions of heterocyclic halogeno compounds with nucleophiles (XXXIV): Ring contraction of 4‐chloropyrimidine‐1‐oxides into isoxazoles in liquid ammonia
JPS59144759A (ja) ２−クロロニコチン酸の製造方法
US3787426A (en) Manufacture of 1,1-disubstituted-4,4-bipyridylium salts
JP3516454B2 (ja) ３‐アミノ‐２‐クロロ‐４‐アルキルピリジン又は‐４‐アリールピリジンの製造方法
CA2382861A1 (en) Process for preparing a 1-substituted 5-hydroxymethyl imidazole
JPH03223252A (ja) 置換メチルアミン類の製造方法
JPS5818383A (ja) ベンゾジアゼピン化合物の新規製造方法
Hirota et al. Pyrimidine derivatives and related compounds. Part 37. Novel nucleophilic substitutions of 5-bromo-6-methyluracils or 5-bromo-6-bromomethyluracils with aromatic amines
Vajda et al. Direct substitution in pyridine ring systems by basic reagents
US2310172A (en) Vitamin b6 intermediate
EP0226558A2 (en) Chemical intermediates and methods for their preparation

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead